PDB: 45677 件ウェブページステータス検索Chemie searchBIRD

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4CDF	Human DPP1 in complex with (2S,4S)-N-((1S)-1-cyano-2-(4-(4- cyanophenyl)phenyl)ethyl)-4-hydroxy-piperidine-2-carboxamide 分子名称: (2S,4S)-N-[(2S)-1-azanylidene-3-[4-(4-cyanophenyl)phenyl]propan-2-yl]-4-oxidanyl-piperidine-2-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... 著者 Debreczeni, J, Edman, K, Furber, M, Tiden, A, Gardiner, P, Mete, T, Ford, R, Millichip, I, Stein, L, Mather, A, Kinchin, E, Luckhurst, C, Cage, P, Sanghanee, H, Breed, J, Wissler, L. 登録日 2013-10-31 公開日 2014-03-19 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Cathepsin C Inhibitors: Property Optimization and Identification of a Clinical Candidate. J.Med.Chem., 57, 2014
3VQ1	Crystal structure of mouse TLR4/MD-2/lipid IVa complex 分子名称: (R)-((2R,3S,4R,5R,6R)-3-HYDROXY-2-(HYDROXYMETHYL)-5-((R)-3-HYDROXYTETRADECANAMIDO)-6-(PHOSPHONOOXY)TETRAHYDRO-2H-PYRAN-4-YL) 3-HYDROXYTETRADECANOATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Ohto, U, Shimizu, T. 登録日 2012-03-17 公開日 2012-05-09 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural basis of species-specific endotoxin sensing by innate immune receptor TLR4/MD-2 Proc.Natl.Acad.Sci.USA, 109, 2012
3VIB	Structural basis for multidrug recognition and antimicrobial resistance by MTRR, an efflux pump regulator from Neisseria Gonorrhoeae 分子名称: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, MtrR, PHOSPHATE ION 著者 Kumaraswami, M, Shafer, W.M, Brennan, R.G. 登録日 2011-09-27 公開日 2012-10-03 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural basis for multidrug recognitionand antimicrobial resistance by MTRR, an efflux pump regulator from Neisseria Gonorrhoeae TO BE PUBLISHED
4BLY	CRYSTAL STRUCTURE OF FUNGAL VERSATILE PEROXIDASE I FROM PLEUROTUS OSTREATUS - CRYSTAL FORM V 分子名称: CALCIUM ION, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, ... 著者 Medrano, F.J, Romero, A. 登録日 2013-05-05 公開日 2014-01-15 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.794 Å) 主引用文献 Ligninolytic Peroxidase Genes in the Oyster Mushroom Genome: Heterologous Expression, Molecular Structure, Catalytic and Stability Properties, and Lignin-Degrading Ability. Biotechnol.Biofuels, 7, 2014
4C2X	Human N-myristoyltransferase isoform 2 (NMT2) 分子名称: 2-oxopentadecyl-CoA, GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE 2, MAGNESIUM ION 著者 Thinon, E, Serwa, R.A, Brannigan, J.A, Brassat, U, Wright, M.H, Heal, W.P, Wilkinson, A.J, Mann, D.J, Tate, E.W. 登録日 2013-08-20 公開日 2014-10-01 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.33 Å) 主引用文献 Global Profiling of Co- and Post-Translationally N-Myristoylated Proteomes in Human Cells. Nat.Commun., 5, 2014
3VN9	Rifined Crystal structure of non-phosphorylated MAP2K6 in a putative auto-inhibition state 分子名称: 9-{5-O-[(R)-hydroxy{[(S)-hydroxy(phosphonoamino)phosphoryl]oxy}phosphoryl]-beta-L-ribofuranosyl}-9H-purin-6-amine, Dual specificity mitogen-activated protein kinase kinase 6, MAGNESIUM ION 著者 Kinoshita, T, Matsuzaka, H, Nakai, R, Kirii, Y, Yokota, K, Tada, T, Matsumoto, T. 登録日 2012-01-05 公開日 2012-02-29 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal structure of non-phosphorylated MAP2K6 in a putative auto-inhibition state J.Biochem., 151, 2012
4BPQ	Structure and substrate induced conformational changes of the secondary citrate-sodium symporter CitS revealed by electron crystallography 分子名称: CITRATE:SODIUM SYMPORTER 著者 Kebbel, F, Kurz, M, Arheit, M, Gruetter, M.G, Stahlberg, H. 登録日 2013-05-27 公開日 2013-07-17 最終更新日 2024-05-08 実験手法 ELECTRON CRYSTALLOGRAPHY (6 Å) 主引用文献 Structure and Substrate-Induced Conformational Changes of the Secondary Citrate/Sodium Symporter Cits Revealed by Electron Crystallography. Structure, 21, 2013
4BTY	Crystal structure of human vascular adhesion protein-1 in complex with pyridazinone inhibitors 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-[4-(4-methylpiperazin-1-yl)phenylamino]-2-(4-chlorophenyl)-6-(1H-1,2,4-triazol-5-yl)-3(2H)-pyridazinone, ... 著者 Bligt-Linden, E, Pihlavisto, M, Szatmari, I, Otwinowski, Z, Smith, D.J, Lazar, L, Fulop, F, Salminen, T.A. 登録日 2013-06-19 公開日 2013-12-18 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Novel Pyridazinone Inhibitors for Vascular Adhesion Protein- 1 (Vap-1): Old Target - New Inhibition Mode. J.Med.Chem., 56, 2013
3W05	Crystal structure of Oryza sativa DWARF14 (D14) in complex with PMSF 分子名称: 1,2-ETHANEDIOL, Dwarf 88 esterase, phenylmethanesulfonic acid 著者 Kagiyama, M, Hirano, Y, Mori, T, Kim, S.Y, Kyozuka, J, Seto, Y, Yamaguchi, S, Hakoshima, T. 登録日 2012-10-19 公開日 2013-01-23 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 Structures of D14 and D14L in the strigolactone and karrikin signaling pathways Genes Cells, 18, 2013
3W0T	Human Glyoxalase I with an N-hydroxypyridone derivative inhibitor 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Lactoylglutathione lyase, N-[3-(1-hydroxy-6-oxo-4-phenyl-1,6-dihydropyridin-2-yl)phenyl]methanesulfonamide, ... 著者 Fukami, T.A, Irie, M, Matsuura, T. 登録日 2012-11-02 公開日 2013-11-06 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.351 Å) 主引用文献 N-Hydroxypyridone-based glyoxalase I inhibitors mimicking binding interactions of the substrate To be Published
3VF8	Crystal Structure of Spleen Tyrosine Kinase Syk Catalytic Domain with Pyrazolylbenzimidazole Inhibitor 416 分子名称: 3-[5-(5-ethoxy-6-fluoro-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-1,1-diethylurea, Tyrosine-protein kinase SYK 著者 McLean, L.R, Zhang, Y. 登録日 2012-01-09 公開日 2012-05-02 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 X-ray crystallographic structure-based design of selective thienopyrazole inhibitors for interleukin-2-inducible tyrosine kinase. Bioorg.Med.Chem.Lett., 22, 2012
4AJT	The crystal structure of mouse protein-Z dependent protease inhibitor(mZPI) 分子名称: PROTEIN Z-DEPENDENT PROTEASE INHIBITOR 著者 Yan, Y, Zhou, A. 登録日 2012-02-19 公開日 2012-12-05 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural Basis for Catalytic Activation of Protein Z-Dependent Protease Inhibitor (Zpi) by Protein Z. Blood, 120, 2012
4AHN	R121H - Angiogenin mutants and amyotrophic lateral sclerosis - a biochemical and biological analysis 分子名称: ANGIOGENIN, CHLORIDE ION 著者 Thiyagarajan, N, Ferguson, R, Saha, S, Pham, T, Subramanian, V, Acharya, K.R. 登録日 2012-02-06 公開日 2012-10-10 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.977 Å) 主引用文献 Structural and Molecular Insights Into the Mechanism of Action of Human Angiogenin-Als Variants in Neurons. Nat.Commun., 3, 2012
4AOH	Structural snapshots and functional analysis of human angiogenin variants associated with Amyotrophic Lateral Sclerosis (ALS) 分子名称: ANGIOGENIN, D(-)-TARTARIC ACID, L(+)-TARTARIC ACID 著者 Thiyagarajan, N, Ferguson, R, Subramanian, V, Acharya, K.R. 登録日 2012-03-27 公開日 2012-10-10 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.041 Å) 主引用文献 Structural and Molecular Insights Into the Mechanism of Action of Human Angiogenin-Als Variants in Neurons Nat.Commun., 3, 2012
3V93	unliganded structure of TcrPDEC1 catalytic domain 分子名称: Cyclic nucleotide specific phosphodiesterase, MAGNESIUM ION, ZINC ION 著者 Wang, H, Kunz, S, Chen, G, Seebeck, T, Wan, Y, Robinson, H, Martinelli, S, Ke, H. 登録日 2011-12-23 公開日 2012-02-22 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Biological and structural characterization of Trypanosoma cruzi phosphodiesterase C and Implications for design of parasite selective inhibitors. J.Biol.Chem., 287, 2012
3VMR	Crystal structure of Staphylococcus aureus membrane-bound transglycosylase in complex with moenomycin 分子名称: MOENOMYCIN, Monofunctional glycosyltransferase 著者 Huang, C.Y, Shih, H.W, Lin, L.Y, Tien, Y.W, Cheng, T.J.R, Cheng, W.C, Wong, C.H, Ma, C. 登録日 2011-12-15 公開日 2012-04-18 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.688 Å) 主引用文献 Crystal structure of Staphylococcus aureus transglycosylase in complex with a lipid II analog and elucidation of peptidoglycan synthesis mechanism Proc.Natl.Acad.Sci.USA, 109, 2012
4AQ0	Structure of the Gh92 Family Glycosyl Hydrolase Ccman5 in complex with deoxymannojirimycin 分子名称: 1-DEOXYMANNOJIRIMYCIN, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ... 著者 Baranova, E, Tiels, P, Callewaert, N, Remaut, H. 登録日 2012-04-12 公開日 2013-02-06 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 A Bacterial Glycosidase Enables Mannose-6-Phosphate Modification and Improved Cellular Uptake of Yeast-Produced Recombinant Human Lysosomal Enzymes. Nat.Biotechnol., 30, 2012
4A55	Crystal structure of p110alpha in complex with iSH2 of p85alpha and the inhibitor PIK-108 分子名称: PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT ALPHA, PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT ALPHA ISOFORM, PIK-108 著者 Hon, W.-C, Berndt, A, Williams, R.L. 登録日 2011-10-24 公開日 2011-12-28 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Regulation of Lipid Binding Underlies the Activation Mechanism of Class Ia Pi3-Kinases. Oncogene, 31, 2012
4AH6	Human mitochondrial aspartyl-tRNA synthetase 分子名称: ASPARTATE--TRNA LIGASE, MITOCHONDRIAL 著者 Neuenfeldt, A, Sissler, M, Lorber, B, Florentz, C, Sauter, C. 登録日 2012-02-03 公開日 2013-01-09 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.7 Å) 主引用文献 Thermodynamic Properties Distinguish Human Mitochondrial Aspartyl-tRNA Synthetase from Bacterial Homolog with Same 3D Architecture Nucleic Acids Res., 41, 2013
4AHJ	I46V - Angiogenin mutants and amyotrophic lateral sclerosis - a biochemical and biological analysis 分子名称: ANGIOGENIN, D(-)-TARTARIC ACID 著者 Thiyagarajan, N, Ferguson, R, Saha, S, Pham, T, Subramanian, V, Acharya, K.R. 登録日 2012-02-06 公開日 2012-10-10 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.032 Å) 主引用文献 Structural and Molecular Insights Into the Mechanism of Action of Human Angiogenin-Als Variants in Neurons. Nat.Commun., 3, 2012
4A63	Crystal structure of the p73-ASPP2 complex at 2.6A resolution 分子名称: ACETATE ION, APOPTOSIS STIMULATING OF P53 PROTEIN 2, TUMOUR PROTEIN 73, ... 著者 Canning, P, Sharpe, T, Krojer, T, Savitsky, P, Cooper, C.D.O, Salah, E, Keates, T, Muniz, J, Vollmar, M, von Delft, F, Weigelt, J, Arrowsmith, C, Bountra, C, Edwards, A, Bullock, A.N. 登録日 2011-10-31 公開日 2011-12-21 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Structural Basis for Aspp2 Recognition by the Tumor Suppressor P73. J.Mol.Biol., 423, 2012
3VHZ	Crystal structure of the trans isomer of the L93A mutant of bacteriorhodopsin 分子名称: 2,3-DI-PHYTANYL-GLYCEROL, 3-O-sulfo-beta-D-galactopyranose-(1-6)-alpha-D-mannopyranose-(1-2)-alpha-D-glucopyranose, Bacteriorhodopsin, ... 著者 Kouyama, T, Zhang, J. 登録日 2011-09-13 公開日 2012-06-13 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of the O intermediate of the Leu93Ala mutant of bacteriorhodopsin Proteins, 80, 2012
4AHF	K17E - Angiogenin mutants and amyotrophic lateral sclerosis - a biochemical and biological analysis 分子名称: 1,2-ETHANEDIOL, ANGIOGENIN, SULFATE ION 著者 Thiyagarajan, N, Ferguson, R, Saha, S, Pham, T, Subramanian, V, Acharya, K.R. 登録日 2012-02-06 公開日 2012-10-10 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.115 Å) 主引用文献 Structural and Molecular Insights Into the Mechanism of Action of Human Angiogenin-Als Variants in Neurons. Nat.Commun., 3, 2012
3SP5	Crystal structure of human 14-3-3 sigma C38V/N166H in complex with TASK-3 peptide and stabilizer Cotylenol 分子名称: 14-3-3 protein sigma, Cotylenol, MAGNESIUM ION, ... 著者 Anders, C, Schumacher, B, Ottmann, C. 登録日 2011-07-01 公開日 2016-05-04 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface. Chem.Biol., 20, 2013
3ZZR	Crystal structure of the CG11501 protein in P21212 spacegroup 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, ... 著者 Coste, F, Roussel, A. 登録日 2011-09-02 公開日 2012-07-11 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Crystal Structure of Diedel, a Marker of the Immune Response of Drosophila Melanogaster. Plos One, 7, 2012

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