8GLK
 
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8GLJ
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8GLH
 | | Crystal Structure of Human CD1b in Complex with Endogenous PC C40:5 | | 分子名称: | (11E)-hexadec-11-enoic acid, 1,2-ETHANEDIOL, Beta-2-microglobulin, ... | | 著者 | Farquhar, R, Rossjohn, J, Shahine, A. | | 登録日 | 2023-03-22 | | 公開日 | 2023-09-20 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | CD1 lipidomes reveal lipid-binding motifs and size-based antigen-display mechanisms.
Cell, 186, 2023
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8GLG
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8GL8
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8GL7
 | | AncAR1 - progesterone - Tif2 | | 分子名称: | Ancestral androgen receptor, GLYCEROL, Nuclear receptor coactivator 2, ... | | 著者 | Little, M.M, Ortlund, E.A. | | 登録日 | 2023-03-21 | | 公開日 | 2024-06-26 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Evolutionary tuning of a key helix drove androgen selectivity
To Be Published
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8GL6
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8GKZ
 | | Human mitochondrial serine hydroxymethyltransferase (SHMT2) Y105F in complex with PLP, glycine and AGF362 inhibitor | | 分子名称: | GLYCINE, N-{4-[4-(2-amino-4-oxo-3,4-dihydro-5H-pyrrolo[3,2-d]pyrimidin-5-yl)butyl]-3-fluorothiophene-2-carbonyl}-L-glutamic acid, PYRIDOXAL-5'-PHOSPHATE, ... | | 著者 | Katinas, J.M, Dann III, C.E. | | 登録日 | 2023-03-20 | | 公開日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Structural Characterization of 5-Substituted Pyrrolo[3,2- d ]pyrimidine Antifolate Inhibitors in Complex with Human Serine Hydroxymethyl Transferase 2.
Biochemistry, 2024
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8GKY
 | | Human mitochondrial serine hydroxymethyltransferase (SHMT2) Y105F in complex with PLP, glycine and AGF359 inhibitor | | 分子名称: | GLYCINE, N-{4-[3-(2-amino-4-oxo-3,4-dihydro-5H-pyrrolo[3,2-d]pyrimidin-5-yl)propyl]-2-fluorobenzoyl}-L-glutamic acid, PYRIDOXAL-5'-PHOSPHATE, ... | | 著者 | Katinas, J.M, Dann III, C.E. | | 登録日 | 2023-03-20 | | 公開日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.77 Å) | | 主引用文献 | Structural Characterization of 5-Substituted Pyrrolo[3,2- d ]pyrimidine Antifolate Inhibitors in Complex with Human Serine Hydroxymethyl Transferase 2.
Biochemistry, 2024
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8GKW
 | | Human mitochondrial serine hydroxymethyltransferase (SHMT2) in complex with PLP, glycine and AGF359 inhibitor | | 分子名称: | GLYCINE, N-{4-[3-(2-amino-4-oxo-3,4-dihydro-5H-pyrrolo[3,2-d]pyrimidin-5-yl)propyl]-2-fluorobenzoyl}-L-glutamic acid, PYRIDOXAL-5'-PHOSPHATE, ... | | 著者 | Katinas, J.M, Dann III, C.E. | | 登録日 | 2023-03-20 | | 公開日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | | 主引用文献 | Structural Characterization of 5-Substituted Pyrrolo[3,2- d ]pyrimidine Antifolate Inhibitors in Complex with Human Serine Hydroxymethyl Transferase 2.
Biochemistry, 2024
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8GKV
 | | Crystal structure of anti-adaptor IraP that regulates RpoS proteolysis | | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | | 著者 | Shaw, G.X, Gan, J, Suburaman, P, Battesti, A, Zhou, Y.N, Wickner, S, Gottesman, S, Ji, X. | | 登録日 | 2023-03-20 | | 公開日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.351 Å) | | 主引用文献 | Structural and functional study of anti-adaptor IraP-mediated regulation of RpoS proteolysis
to be published
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8GKU
 | | Human mitochondrial serine hydroxymethyltransferase (SHMT2) in complex with PLP, glycine and AGF355 inhibitor | | 分子名称: | GLYCINE, N-{4-[5-(2-amino-4-oxo-3,4-dihydro-5H-pyrrolo[3,2-d]pyrimidin-5-yl)pentyl]-2-fluorobenzoyl}-D-glutamic acid, PYRIDOXAL-5'-PHOSPHATE, ... | | 著者 | Katinas, J.M, Dann III, C.E. | | 登録日 | 2023-03-20 | | 公開日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (3.06 Å) | | 主引用文献 | Structural Characterization of 5-Substituted Pyrrolo[3,2- d ]pyrimidine Antifolate Inhibitors in Complex with Human Serine Hydroxymethyl Transferase 2.
Biochemistry, 2024
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8GKT
 | | Human mitochondrial serine hydroxymethyltransferase (SHMT2) in complex with PLP, glycine and AGF320 inhibitor | | 分子名称: | N-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE], N-{5-[5-(2-amino-4-oxo-3,4-dihydro-5H-pyrrolo[3,2-d]pyrimidin-5-yl)pentyl]thiophene-2-carbonyl}-L-glutamic acid, Serine hydroxymethyltransferase, ... | | 著者 | Katinas, J.M, Dann III, C.E. | | 登録日 | 2023-03-20 | | 公開日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | | 主引用文献 | Structural Characterization of 5-Substituted Pyrrolo[3,2- d ]pyrimidine Antifolate Inhibitors in Complex with Human Serine Hydroxymethyl Transferase 2.
Biochemistry, 2024
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8GKS
 | | Human mitochondrial serine hydroxymethyltransferase (SHMT2) in complex with PLP, glycine and AGF291 inhibitor | | 分子名称: | GLYCINE, N-{4-[3-(2-amino-4-oxo-3,4-dihydro-5H-pyrrolo[3,2-d]pyrimidin-5-yl)propyl]benzoyl}-L-glutamic acid, PYRIDOXAL-5'-PHOSPHATE, ... | | 著者 | Katinas, J.M, Dann III, C.E. | | 登録日 | 2023-03-20 | | 公開日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | | 主引用文献 | Structural Characterization of 5-Substituted Pyrrolo[3,2- d ]pyrimidine Antifolate Inhibitors in Complex with Human Serine Hydroxymethyl Transferase 2.
Biochemistry, 2024
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8GKR
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8GKF
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8GKC
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8GK8
 | | R21A Staphylococcus aureus pyruvate carboxylase | | 分子名称: | 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ACETYL COENZYME *A, COENZYME A, ... | | 著者 | Laseke, A.J, St.Maurice, M. | | 登録日 | 2023-03-17 | | 公開日 | 2023-08-30 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | | 主引用文献 | Allosteric Site at the Biotin Carboxylase Dimer Interface Mediates Activation and Inhibition in Staphylococcus aureus Pyruvate Carboxylase.
Biochemistry, 62, 2023
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8GK5
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8GJV
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8GJR
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8GJB
 | | L-threonine 3-Dehydrogenase from Trypanosoma cruzi in complex with NAD and acetate | | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, GLYCEROL, ... | | 著者 | Mercaldi, G.F, Faria, J.N, Fagundes, M, Bezerra, E.H.S, Cordeiro, A.T. | | 登録日 | 2023-03-15 | | 公開日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Structure, allosteric regulation and metabolic activity of L-threonine 3-Dehydrogenase from Trypanosoma cruzi
To Be Published
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8GJ8
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8GJ4
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8GIX
 | | Chaetomium thermophilum Hir3 | | 分子名称: | 3,3',3''-phosphanetriyltripropanoic acid, Histone transcription regulator 3 homolog | | 著者 | Szurgot, M.R, van Eeuwen, T, Kim, H.J, Marmorstein, R. | | 登録日 | 2023-03-14 | | 公開日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structure of the Hir histone chaperone complex.
Mol.Cell, 2024
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