PDB: 45522 件ウェブページステータス検索Chemie searchBIRD

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3VKA	Crystal structure of MoeO5 soaked for 3 hours in FsPP 分子名称: (2R)-3-(phosphonooxy)-2-{[(2Z,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]oxy}propanoic acid, MAGNESIUM ION, MoeO5 著者 Ren, F, Ko, T.-P, Huang, C.-H, Guo, R.-T. 登録日 2011-11-11 公開日 2012-05-09 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 Insights into the mechanism of the antibiotic-synthesizing enzyme MoeO5 from crystal structures of different complexes Angew.Chem.Int.Ed.Engl., 51, 2012
3LPB	Crystal structure of Jak2 complexed with a potent 2,8-diaryl-quinoxaline inhibitor 分子名称: N-methyl-4-[3-(3,4,5-trimethoxyphenyl)quinoxalin-5-yl]benzenesulfonamide, Tyrosine-protein kinase JAK2 著者 Tavares, G.A, Pissot-Soldermann, C, Gerspacher, M, Furet, P, Kroemer, M. 登録日 2010-02-05 公開日 2010-04-28 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Discovery and SAR of potent, orally available 2,8-diaryl-quinoxalines as a new class of JAK2 inhibitors Bioorg.Med.Chem.Lett., 20, 2010
3L9D	The Crystal Structure of smu.1046c from Streptococcus mutans UA159 分子名称: Putative GTP pyrophosphokinase 著者 Su, X.-D, Huang, Y.H, Liu, X. 登録日 2010-01-05 公開日 2011-01-12 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.484 Å) 主引用文献 The Crystal Structure of smu.1046c from Streptococcus mutans UA159 TO BE PUBLISHED
3VA2	Crystal structure of human Interleukin-5 in complex with its alpha receptor 分子名称: Interleukin-5, Interleukin-5 receptor subunit alpha 著者 Kusano, S, Kukimoto-Niino, M, Shirouzu, M, Yokoyama, S. 登録日 2011-12-28 公開日 2012-07-25 実験手法 X-RAY DIFFRACTION (2.703 Å) 主引用文献 Structural basis of interleukin-5 dimer recognition by its alpha receptor Protein Sci., 21, 2012
3VHD	Hsp90 alpha N-terminal domain in complex with a macrocyclic inhibitor, CH5164840 分子名称: 4-amino-18,20-dimethyl-7-thia-3,5,11,15-tetraazatricyclo[15.3.1.1(2,6)]docosa-1(20),2,4,6(22),17(21),18-hexaene-10,16-dione, Heat shock protein HSP 90-alpha 著者 Fukami, T.A, Ono, N. 登録日 2011-08-24 公開日 2012-07-18 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.52 Å) 主引用文献 Design and synthesis of novel macrocyclic 2-amino-6-arylpyrimidine Hsp90 inhibitors Bioorg.Med.Chem.Lett., 22, 2012
3VKB	Crystal structure of MoeO5 soaked with FsPP overnight 分子名称: CHLORIDE ION, MAGNESIUM ION, MoeO5, ... 著者 Ren, F, Ko, T.-P, Huang, C.-H, Guo, R.-T. 登録日 2011-11-11 公開日 2012-05-09 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Insights into the mechanism of the antibiotic-synthesizing enzyme MoeO5 from crystal structures of different complexes Angew.Chem.Int.Ed.Engl., 51, 2012
3VF9	Crystal Structure of Spleen Tyrosine Kinase Syk Catalytic Domain with Thienopyrazolylindole Inhibitor 027 分子名称: 3-{2-[5-(difluoromethyl)-2H-thieno[3,2-c]pyrazol-3-yl]-1H-indol-6-yl}pentan-3-ol, Tyrosine-protein kinase SYK 著者 McLean, L.R, Zhang, Y. 登録日 2012-01-09 公開日 2012-05-02 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 X-ray crystallographic structure-based design of selective thienopyrazole inhibitors for interleukin-2-inducible tyrosine kinase. Bioorg.Med.Chem.Lett., 22, 2012
3LIC	Crystal Structure of the extracellular domain of the putative histidine kinase soHK1S-Z6 分子名称: 1,2-ETHANEDIOL, Sensor protein 著者 Zhang, Z, Hendrickson, W.A. 登録日 2010-01-24 公開日 2010-05-05 最終更新日 2017-11-01 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural characterization of the predominant family of histidine kinase sensor domains. J.Mol.Biol., 400, 2010
3VQ1	Crystal structure of mouse TLR4/MD-2/lipid IVa complex 分子名称: (R)-((2R,3S,4R,5R,6R)-3-HYDROXY-2-(HYDROXYMETHYL)-5-((R)-3-HYDROXYTETRADECANAMIDO)-6-(PHOSPHONOOXY)TETRAHYDRO-2H-PYRAN-4-YL) 3-HYDROXYTETRADECANOATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Ohto, U, Shimizu, T. 登録日 2012-03-17 公開日 2012-05-09 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural basis of species-specific endotoxin sensing by innate immune receptor TLR4/MD-2 Proc.Natl.Acad.Sci.USA, 109, 2012
3VIB	Structural basis for multidrug recognition and antimicrobial resistance by MTRR, an efflux pump regulator from Neisseria Gonorrhoeae 分子名称: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, MtrR, PHOSPHATE ION 著者 Kumaraswami, M, Shafer, W.M, Brennan, R.G. 登録日 2011-09-27 公開日 2012-10-03 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural basis for multidrug recognitionand antimicrobial resistance by MTRR, an efflux pump regulator from Neisseria Gonorrhoeae TO BE PUBLISHED
3LIB	Crystal Structure of the extracellular domain of the putative histidine kinase mmHK1S-Z3 分子名称: Hypothetical sensory transduction histidine kinase, POTASSIUM ION 著者 Zhang, Z, Hendrickson, W.A. 登録日 2010-01-24 公開日 2010-05-05 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.99 Å) 主引用文献 Structural characterization of the predominant family of histidine kinase sensor domains. J.Mol.Biol., 400, 2010
3LKS	Crystal Structure of HLA B*3501 in complex with influenza NP418 epitope from 1980 strain 分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-35 alpha chain, ... 著者 Gras, S, Kedzierski, L, Valkenburg, S.A, Liu, Y.C, Denholm, J, Richards, M, Rimmelzwaan, G.F, Doherty, P.C, Turner, S.J, Rossjohn, J, Kedzierska, K. 登録日 2010-01-27 公開日 2010-07-07 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Cross-reactive CD8+ T-cell immunity between the pandemic H1N1-2009 and H1N1-1918 influenza A viruses. Proc.Natl.Acad.Sci.USA, 107, 2010
3VUY	Crystal structure of A20 ZF7 in complex with linear tetraubiquitin 分子名称: POTASSIUM ION, Polyubiquitin-C, Tumor necrosis factor alpha-induced protein 3, ... 著者 Nishimasu, H, Ishitani, R, Nureki, O. 登録日 2012-07-09 公開日 2013-02-13 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.981 Å) 主引用文献 Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-kappaB regulation Embo J., 31, 2012
3L6H	Crystal structure of lactococcal OpuAC in its closed-liganded conformation complexed with glycine betaine 分子名称: Betaine ABC transporter permease and substrate binding protein, CHLORIDE ION, TRIMETHYL GLYCINE 著者 Berntsson, R.P.A, Wolters, J.C, Gul, N, Karasawa, A, Thunnissen, A.M.W.H, Slotboom, D.J, Poolman, B. 登録日 2009-12-23 公開日 2010-05-19 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Ligand binding and crystal structures of the substrate-binding domain of the ABC transporter OpuA. Plos One, 5, 2010
3LRB	Structure of E. coli AdiC 分子名称: Arginine/agmatine antiporter 著者 Gao, X, Lu, F, Zhou, L, Shi, Y. 登録日 2010-02-10 公開日 2010-02-23 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (3.61 Å) 主引用文献 Structure and mechanism of an amino acid antiporter Science, 324, 2009
3L7N	Crystal structure of SMU.1228c 分子名称: Putative uncharacterized protein 著者 Fan, X.-X, Wang, K.-T, Su, X.-D. 登録日 2009-12-29 公開日 2010-12-29 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structure of SMU.1228c TO BE PUBLISHED
3VQ5	HIV-1 IN core domain in complex with N-METHYL-1-(4-METHYL-2-PHENYL-1,3-THIAZOL-5-YL)METHANAMINE 分子名称: CADMIUM ION, CHLORIDE ION, N-methyl-1-(4-methyl-2-phenyl-1,3-thiazol-5-yl)methanamine, ... 著者 Wielens, J, Chalmers, D.K, Parker, M.W, Scanlon, M.J. 登録日 2012-03-20 公開日 2013-01-30 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Parallel screening of low molecular weight fragment libraries: do differences in methodology affect hit identification? J Biomol Screen, 18, 2013
3LBY	Crystal structure of SMU.1697c, a putative methyltransferase from streptococcus mutans in complex with SAH 分子名称: Putative uncharacterized protein SMU.1697c, S-ADENOSYL-L-HOMOCYSTEINE 著者 Wang, K.-T, Nan, J, Su, X.-D. 登録日 2010-01-08 公開日 2011-01-12 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of SMU.1697c, a putative methyltransferase from streptococcus mutans in complex with SAH To be published
3VVP	Crystal structure of MATE in complex with Br-NRF 分子名称: 6-bromo-1-ethyl-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid, Putative uncharacterized protein 著者 Tanaka, Y, Ishitani, R, Nureki, O. 登録日 2012-07-27 公開日 2013-04-03 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.91 Å) 主引用文献 Structural basis for the drug extrusion mechanism by a MATE multidrug transporter. Nature, 496, 2013
3LPT	HIV integrase 分子名称: (6-chloro-2-oxo-4-phenyl-1,2-dihydroquinolin-3-yl)acetic acid, 2-[3-[3-(2-hydroxyethoxy)propoxy]propoxy]ethanol, CALCIUM ION, ... 著者 Nicolet, S, Christ, F, Voet, A, Marchand, A, Strelkov, S.V, de Maeyer, M, Chaltin, P, Debyzer, Z. 登録日 2010-02-05 公開日 2010-05-12 最終更新日 2021-11-10 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Rational design of small-molecule inhibitors of the LEDGF/p75-integrase interaction and HIV replication. Nat.Chem.Biol., 6, 2010
3LR0	Periplasmic domain of the risS sensor protein from Burkholderia pseudomallei, iodide phased at low pH 分子名称: IODIDE ION, Sensor protein 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2010-02-10 公開日 2010-06-16 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural basis for pH sensing by the periplasmic domain of the risS histidine kinase from Bukholderia pseudomallei To be Published
3V8T	Crystal Structure of Interleukin-2 Inducible T-cell Kinase Itk Catalytic Domain with Thienopyrazolylindole Inhibitor 477 分子名称: 3-{2-[5-(difluoromethyl)-2H-thieno[3,2-c]pyrazol-3-yl]-1H-indol-6-yl}pentan-3-ol, SULFATE ION, Tyrosine-protein kinase ITK/TSK 著者 McLean, L.R, Zhang, Y. 登録日 2011-12-23 公開日 2012-05-02 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 X-ray crystallographic structure-based design of selective thienopyrazole inhibitors for interleukin-2-inducible tyrosine kinase. Bioorg.Med.Chem.Lett., 22, 2012
3LVB	Crystal structure of the Ferredoxin:NADP+ reductase from maize root at 1.7 angstroms - Test Set Withheld 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Ferredoxin-NADP reductase 著者 Faber, H.R, Karplus, P.A, Aliverti, A, Ferioli, C, Spinola, M. 登録日 2010-02-19 公開日 2010-03-16 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Biochemical and crystallographic characterization of ferredoxin-NADP(+) reductase from nonphotosynthetic tissues Biochemistry, 40, 2001
3LPU	HIV integrase 分子名称: (2S)-2-(6-chloro-2-methyl-4-phenylquinolin-3-yl)pentanoic acid, 2-[3-[3-(2-hydroxyethoxy)propoxy]propoxy]ethanol, CALCIUM ION, ... 著者 Nicolet, S, Christ, F, Voet, A, Marchand, A, Strelkov, S.V, de Maeyer, M, Chaltin, P, Debyzer, Z. 登録日 2010-02-06 公開日 2010-05-12 最終更新日 2021-11-10 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Rational design of small-molecule inhibitors of the LEDGF/p75-integrase interaction and HIV replication. Nat.Chem.Biol., 6, 2010
3LQU	Crystal structure of 3,4-Dihydroxy-2-butanone 4-phosphate synthase complexed with Ribulose-5 phosphate 分子名称: 3,4-dihydroxy-2-butanone 4-phosphate synthase, 5-O-phosphono-D-xylulose 著者 Kumar, P, Karthikeyan, S. 登録日 2010-02-10 公開日 2010-09-15 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.522 Å) 主引用文献 Potential anti-bacterial drug target: structural characterization of 3,4-dihydroxy-2-butanone-4-phosphate synthase from Salmonella typhimurium LT2. Proteins, 78, 2010

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