2PCJ
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![BU of 2pcj by Molmil](/molmil-images/mine/2pcj) | Crystal structure of ABC transporter (aq_297) From Aquifex Aeolicus VF5 | 分子名称: | Lipoprotein-releasing system ATP-binding protein lolD, SULFITE ION | 著者 | Jeyakanthan, J, Kanaujia, S.P, Vasuki Ranjani, C, Sekar, K, Nakagawa, N, Ebihara, A, Kuramitsu, S, Shinkai, A, Shiro, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-03-30 | 公開日 | 2007-10-02 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal structure of ABC transporter (aq_297) From Aquifex Aeolicus VF5 To be Published
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2GUJ
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![BU of 2guj by Molmil](/molmil-images/mine/2guj) | Three dimensional structure of the protein P54332 from Bacillus Subtilis. Northeast Structural Genomics Consortium target sr353. | 分子名称: | Phage-like element PBSX protein xkdM | 著者 | Kuzin, A.P, Zhou, W, Seetharaman, J, Cunningham, K, Janjua, H, Konover, K, Ma, L.C, Xiao, R, Acton, T, Montelione, G, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2006-04-30 | 公開日 | 2006-05-23 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Three dimensional structure of the protein P54332 from Bacillus Subtilis. Northeast Structural Genomics Consortium target sr353. To be Published
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2GP0
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4DHS
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![BU of 4dhs by Molmil](/molmil-images/mine/4dhs) | Small-molecule inhibitors of 14-3-3 protein-protein interactions from virtual screening | 分子名称: | (2-{2-[(3,5-dichlorophenyl)amino]-2-oxoethoxy}phenyl)phosphonic acid, 14-3-3 PROTEIN SIGMA, CHLORIDE ION, ... | 著者 | Thiel, P, Roeglin, L, Kohlbacher, O, Ottmann, C. | 登録日 | 2012-01-30 | 公開日 | 2013-07-31 | 最終更新日 | 2013-09-04 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | Virtual screening and experimental validation reveal novel small-molecule inhibitors of 14-3-3 protein-protein interactions. Chem.Commun.(Camb.), 49, 2013
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2OMZ
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4DMN
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![BU of 4dmn by Molmil](/molmil-images/mine/4dmn) | HIV-1 Integrase Catalytical Core Domain | 分子名称: | (2S)-[6-bromo-4-(4-chlorophenyl)-2-methylquinolin-3-yl](methoxy)ethanoic acid, ARSENIC, HIV-1 Integrase, ... | 著者 | Feng, L, Kvaratskhelia, M. | 登録日 | 2012-02-08 | 公開日 | 2012-03-21 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Multimode, cooperative mechanism of action of allosteric HIV-1 integrase inhibitors. J.Biol.Chem., 287, 2012
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4DNB
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![BU of 4dnb by Molmil](/molmil-images/mine/4dnb) | METHYLATION OF THE ECORI RECOGNITION SITE DOES NOT ALTER DNA CONFORMATION. THE CRYSTAL STRUCTURE OF D(CGCGAM6ATTCGCG) AT 2.0 ANGSTROMS RESOLUTION | 分子名称: | DNA (5'-D(*CP*GP*CP*GP*AP*(6MA)P*TP*TP*CP*GP*CP*G)-3') | 著者 | Frederick, C.A, Quigley, G.J, Van Der Marel, G.A, Van Boom, J.H, Wang, A.H.-J, Rich, A. | 登録日 | 1988-08-29 | 公開日 | 1989-01-09 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Methylation of the EcoRI recognition site does not alter DNA conformation: the crystal structure of d(CGCGAm6ATTCGCG) at 2.0-A resolution. J.Biol.Chem., 263, 1988
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2GV3
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![BU of 2gv3 by Molmil](/molmil-images/mine/2gv3) | Translocation of a tRNA with an extended anticodon through the ribosome | 分子名称: | 5'-R(*GP*GP*CP*CP*AP*GP*AP*CP*UP*CP*CP*CP*GP*AP*AP*UP*CP*UP*GP*GP*CP*C)-3' | 著者 | Phelps, S.S, Gaudin, C, Yoshizawa, S, Benitez, C, Fourmy, D, Joseph, S. | 登録日 | 2006-05-02 | 公開日 | 2006-08-08 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Translocation of a tRNA with an Extended Anticodon Through the Ribosome. J.Mol.Biol., 360, 2006
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2OU8
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![BU of 2ou8 by Molmil](/molmil-images/mine/2ou8) | Structure of Spin-labeled T4 Lysozyme Mutant T115R1 at Room Temperature | 分子名称: | BETA-MERCAPTOETHANOL, Lysozyme, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate | 著者 | Guo, Z, Cascio, D, Hideg, K, Hubbell, W.L. | 登録日 | 2007-02-09 | 公開日 | 2007-06-12 | 最終更新日 | 2023-08-30 | 実験手法 | EPR (1.8 Å), X-RAY DIFFRACTION | 主引用文献 | Structural determinants of nitroxide motion in spin-labeled proteins: Tertiary contact and solvent-inaccessible sites in helix G of T4 lysozyme. Protein Sci., 16, 2007
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4DUM
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![BU of 4dum by Molmil](/molmil-images/mine/4dum) | Co-crystal structure of eIF4E with inhibitor | 分子名称: | (4-{7-[2-(4-chlorophenoxy)ethyl]-2-(methylamino)-6-oxo-6,7-dihydro-1H-purin-8-yl}phenyl)phosphonic acid, 1,2-ETHANEDIOL, Eukaryotic translation initiation factor 4E | 著者 | Min, X, Johnstone, S, Walker, N, Wang, Z. | 登録日 | 2012-02-22 | 公開日 | 2012-04-11 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Structure-Guided Design, Synthesis, and Evaluation of Guanine-Derived Inhibitors of the eIF4E mRNA-Cap Interaction. J.Med.Chem., 55, 2012
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2HA5
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![BU of 2ha5 by Molmil](/molmil-images/mine/2ha5) | Crystal structure of mutant S203A of acetylcholinesterase complexed with acetylthiocholine | 分子名称: | 2-(TRIMETHYLAMMONIUM)ETHYL THIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... | 著者 | Bourne, Y, Radic, Z, Sulzenbacher, G, Kim, E, Taylor, P, Marchot, P. | 登録日 | 2006-06-12 | 公開日 | 2006-07-18 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Substrate and product trafficking through the active center gorge of acetylcholinesterase analyzed by crystallography and equilibrium binding J.Biol.Chem., 281, 2006
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4DVJ
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![BU of 4dvj by Molmil](/molmil-images/mine/4dvj) | Crystal structure of a putative zinc-dependent alcohol dehydrogenase protein from Rhizobium etli CFN 42 | 分子名称: | Putative zinc-dependent alcohol dehydrogenase protein | 著者 | Agarwal, R, Chamala, S, Evans, B, Foti, R, Gizzi, A, Hellerich, B, Kar, A, Lafleur, J, Siedel, R, Villigas, G, Zencheck, W, Almo, S.C, Swaminathan, S, New York Structural Genomics Research Consortium (NYSGRC) | 登録日 | 2012-02-23 | 公開日 | 2012-03-07 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Crystal structure of a putative zinc-dependent alcohol dehydrogenase protein from Rhizobium etli CFN 42 To be Published
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2PBE
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2PNJ
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![BU of 2pnj by Molmil](/molmil-images/mine/2pnj) | Crystal structure of human ferrochelatase mutant with Phe 337 replaced by Ala | 分子名称: | CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, Ferrochelatase, ... | 著者 | Dailey, H.A, Wu, C.-K, Horanyi, P, Medlock, A.E, Najahi-Missaoui, W, Burden, A.E, Dailey, T.A, Rose, J.P. | 登録日 | 2007-04-24 | 公開日 | 2007-10-02 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Altered orientation of active site residues in variants of human ferrochelatase. Evidence for a hydrogen bond network involved in catalysis Biochemistry, 46, 2007
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4BHN
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![BU of 4bhn by Molmil](/molmil-images/mine/4bhn) | Crystal Structures of Ask1-inhibitor Complexes | 分子名称: | 4-tert-butyl-N-[6-(1H-pyrazol-4-yl)imidazo[1,2-a]pyridin-2-yl]benzamide, GLYCEROL, MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 5 | 著者 | Singh, O, Shillings, A, Craggs, P, Wall, I, Rowland, P, Skarzynski, T, Hobbs, C.I, Hardwick, P, Tanner, R, Blunt, M, Witty, D.R, Smith, K.J. | 登録日 | 2013-04-04 | 公開日 | 2013-07-03 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal Structures of Ask1-Inhibtor Complexes Provide a Platform for Structure Based Drug Design. Protein Sci., 22, 2013
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4BIC
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![BU of 4bic by Molmil](/molmil-images/mine/4bic) | Crystal Structures of Ask1-inhibitor Complexes | 分子名称: | GLYCEROL, MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 5, N-(2-aminoethyl)-5-{1H-pyrrolo[2,3-b]pyridin-3-yl}thiophene-2-sulfonamide | 著者 | Singh, O, Shillings, A, Craggs, P, Wall, I, Rowland, P, Skarzynski, T, Hobbs, C.I, Hardwick, P, Tanner, R, Blunt, M, Witty, D.R, Smith, K.J. | 登録日 | 2013-04-10 | 公開日 | 2013-07-03 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | 主引用文献 | Crystal Structures of Ask1-Inhibtor Complexes Provide a Platform for Structure Based Drug Design. Protein Sci., 22, 2013
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4AYC
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![BU of 4ayc by Molmil](/molmil-images/mine/4ayc) | RNF8 RING domain structure | 分子名称: | CHLORIDE ION, E3 UBIQUITIN-PROTEIN LIGASE RNF8, GLYCEROL, ... | 著者 | Mattiroli, F, Vissers, J.H.A, Van Dijk, W.J, Ikpa, P, Citterio, E, Vermeulen, W, Marteijn, J.A, Sixma, T.K. | 登録日 | 2012-06-20 | 公開日 | 2012-09-26 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Rnf168 Ubiquitinates K13-15 on H2A/H2Ax to Drive DNA Damage Signaling Cell(Cambridge,Mass.), 150, 2012
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4B96
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![BU of 4b96 by Molmil](/molmil-images/mine/4b96) | Family 3b carbohydrate-binding module from the biomass sensoring system of Clostridium clariflavum | 分子名称: | CALCIUM ION, CELLULOSE BINDING DOMAIN-CONTAINING PROTEIN, CHLORIDE ION | 著者 | Yaniv, O, Reddy, Y.H.K, Yoffe, H, Shimon, L.J.W, Bayer, E.A, Lamed, R, Frolow, F. | 登録日 | 2012-09-02 | 公開日 | 2013-09-18 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.911 Å) | 主引用文献 | Structure of Cbm3B from the Biomass Sensoring System of Clostridium Clarifalvum To be Published
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4B9K
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![BU of 4b9k by Molmil](/molmil-images/mine/4b9k) | pVHL-ELOB-ELOC complex_(2S,4R)-1-(3-amino-2-methylbenzoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide bound | 分子名称: | (2S,4R)-1-(3-amino-2-methylbenzoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide, ACETATE ION, TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 1, ... | 著者 | Buckley, D.L, Gustafson, J.L, VanMolle, I, Roth, A.G, SeopTae, H, Gareiss, P.C, Jorgensen, W.L, Ciulli, A, Crews, C.M. | 登録日 | 2012-09-05 | 公開日 | 2012-10-24 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Small-Molecule Inhibitors of the Interaction between the E3 Ligase Vhl and Hif1 Alpha Angew.Chem.Int.Ed.Engl., 51, 2012
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4B46
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2Q0R
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![BU of 2q0r by Molmil](/molmil-images/mine/2q0r) | Structure of Pectenotoxin-2 Bound to Actin | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Actin, CALCIUM ION, ... | 著者 | Allingham, J.S, Miles, C.O, Rayment, I. | 登録日 | 2007-05-22 | 公開日 | 2007-07-17 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | A structural basis for regulation of actin polymerization by pectenotoxins. J.Mol.Biol., 371, 2007
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2PQD
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![BU of 2pqd by Molmil](/molmil-images/mine/2pqd) | A100G CP4 EPSPS liganded with (R)-difluoromethyl tetrahedral reaction intermediate analog | 分子名称: | (3R,4S,5R)-5-[(1R)-1-CARBOXY-2,2-DIFLUORO-1-(PHOSPHONOOXY)ETHOXY]-4-HYDROXY-3-(PHOSPHONOOXY)CYCLOHEX-1-ENE-1-CARBOXYLIC ACID, 3-phosphoshikimate 1-carboxyvinyltransferase | 著者 | Healy-Fried, M.L, Funke, T, Han, H, Schonbrunn, E. | 登録日 | 2007-05-01 | 公開日 | 2008-03-11 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Differential inhibition of class I and class II 5-enolpyruvylshikimate-3-phosphate synthases by tetrahedral reaction intermediate analogues. Biochemistry, 46, 2007
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2Q8G
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![BU of 2q8g by Molmil](/molmil-images/mine/2q8g) | Structure of pyruvate dehydrogenase kinase isoform 1 in complex with glucose-lowering drug AZD7545 | 分子名称: | 4-[(3-CHLORO-4-{[(2R)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANOYL]AMINO}PHENYL)SULFONYL]-N,N-DIMETHYLBENZAMIDE, POTASSIUM ION, [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1 | 著者 | Kato, M, Li, J, Chuang, J.L, Chuang, D.T. | 登録日 | 2007-06-10 | 公開日 | 2007-07-24 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Distinct Structural Mechanisms for Inhibition of Pyruvate Dehydrogenase Kinase Isoforms by AZD7545, Dichloroacetate, and Radicicol. Structure, 15, 2007
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2HSY
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2HTT
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![BU of 2htt by Molmil](/molmil-images/mine/2htt) | Ruthenium Hexammine ion interactions with Z-DNA | 分子名称: | DNA (5'-D(*DCP*DGP*DCP*DGP*DCP*DA)-3'), DNA (5'-D(*DTP*DGP*DCP*DGP*DCP*DG)-3'), DNA (5'-D(P*DTP*DG)-3'), ... | 著者 | Bharanidharan, D, Thiyagarajan, S, Gautham, N. | 登録日 | 2006-07-26 | 公開日 | 2006-08-08 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Hexammineruthenium(III) ion interactions with Z-DNA Acta Crystallogr.,Sect.F, 63, 2007
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