4BHN
Crystal Structures of Ask1-inhibitor Complexes
Summary for 4BHN
Entry DOI | 10.2210/pdb4bhn/pdb |
Related | 4BF2 4BIB 4BIC 4BID 4BIE |
Descriptor | MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 5, 4-tert-butyl-N-[6-(1H-pyrazol-4-yl)imidazo[1,2-a]pyridin-2-yl]benzamide, GLYCEROL, ... (4 entities in total) |
Functional Keywords | transferase, structure based design |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Cytoplasm: Q99683 |
Total number of polymer chains | 2 |
Total formula weight | 75939.94 |
Authors | Singh, O.,Shillings, A.,Craggs, P.,Wall, I.,Rowland, P.,Skarzynski, T.,Hobbs, C.I.,Hardwick, P.,Tanner, R.,Blunt, M.,Witty, D.R.,Smith, K.J. (deposition date: 2013-04-04, release date: 2013-07-03, Last modification date: 2023-12-20) |
Primary citation | Singh, O.,Shillings, A.,Craggs, P.,Wall, I.,Rowland, P.,Skarzynski, T.,Hobbs, C.I.,Hardwick, P.,Tanner, R.,Blunt, M.,Witty, D.R.,Smith, K.J. Crystal Structures of Ask1-Inhibtor Complexes Provide a Platform for Structure Based Drug Design. Protein Sci., 22:1071-, 2013 Cited by PubMed: 23776076DOI: 10.1002/PRO.2298 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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