2OEA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2oea by Molmil](/molmil-images/mine/2oea) | High-pressure structure of pseudo-WT T4 Lysozyme | 分子名称: | BETA-MERCAPTOETHANOL, CHLORIDE ION, Lysozyme | 著者 | Collins, M.D, Quillin, M.L, Matthews, B.W, Gruner, S.M. | 登録日 | 2006-12-28 | 公開日 | 2007-01-30 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Structural Rigidity of a Large Cavity-containing Protein Revealed by High-pressure Crystallography. J.Mol.Biol., 367, 2007
|
|
2OEB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2oeb by Molmil](/molmil-images/mine/2oeb) | The crystal structure of gene product Af1862 from Archaeoglobus fulgidus | 分子名称: | Hypothetical protein | 著者 | Zhang, R, Evdokimova, E, Kagan, O, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2006-12-28 | 公開日 | 2007-01-30 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | 主引用文献 | The crystal structure of gene product Af1862 from Archaeoglobus fulgidus To be Published
|
|
2OE7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2oe7 by Molmil](/molmil-images/mine/2oe7) | High-Pressure T4 Lysozyme | 分子名称: | BETA-MERCAPTOETHANOL, CHLORIDE ION, Lysozyme | 著者 | Collins, M.D, Quillin, M.L, Matthews, B.W, Gruner, S.M. | 登録日 | 2006-12-28 | 公開日 | 2007-01-30 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural Rigidity of a Large Cavity-containing Protein Revealed by High-pressure Crystallography. J.Mol.Biol., 367, 2007
|
|
4BK6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4bk6 by Molmil](/molmil-images/mine/4bk6) | |
4BLD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4bld by Molmil](/molmil-images/mine/4bld) | Crystal structure of a human Suppressor of fused (SUFU)-GLI3p complex | 分子名称: | MALTOSE-BINDING PERIPLASMIC PROTEIN, SUPPRESSOR OF FUSED HOMOLOG, TRANSCRIPTIONAL ACTIVATOR GLI3, ... | 著者 | Cherry, A.L, Finta, C, Karlstrom, M, De Sanctis, D, Toftgard, R, Jovine, L. | 登録日 | 2013-05-02 | 公開日 | 2013-11-27 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.802 Å) | 主引用文献 | Structural Basis of Sufu-GLI Interaction in Hedgehog Signalling Regulation Acta Crystallogr.,Sect.D, 69, 2013
|
|
2JSK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2jsk by Molmil](/molmil-images/mine/2jsk) | Monomeric Human Telomere DNA Tetraplex with 3+1 Strand Fold Topology, Two Edgewise Loops and Double-Chain Reversal Loop, 16 G Form 1, NMR, 10 Structures | 分子名称: | HUMAN TELOMERE DNA | 著者 | Kuryavyi, V.V, Phan, A.T, Luu, K.N, Patel, D.J. | 登録日 | 2007-07-07 | 公開日 | 2008-07-08 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of two intramolecular G-quadruplexes formed by natural human telomere sequences in K+ solution. Nucleic Acids Res., 35, 2007
|
|
4BIB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4bib by Molmil](/molmil-images/mine/4bib) | Crystal Structures of Ask1-inhibitor Complexes | 分子名称: | 3-cyano-4-(piperidin-4-yloxy)-1H-indole-7-carboxamide, ACETATE ION, GLYCEROL, ... | 著者 | Singh, O, Shillings, A, Craggs, P, Wall, I, Rowland, P, Skarzynski, T, Hobbs, C.I, Hardwick, P, Tanner, R, Blunt, M, Witty, D.R, Smith, K.J. | 登録日 | 2013-04-10 | 公開日 | 2013-07-03 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | 主引用文献 | Crystal Structures of Ask1-Inhibtor Complexes Provide a Platform for Structure Based Drug Design. Protein Sci., 22, 2013
|
|
4BL0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4bl0 by Molmil](/molmil-images/mine/4bl0) | Crystal structure of yeast Bub3-Bub1 bound to phospho-Spc105 | 分子名称: | CELL CYCLE ARREST PROTEIN BUB3, CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1, MAGNESIUM ION, ... | 著者 | Primorac, I, Weir, J.R, Musacchio, A. | 登録日 | 2013-04-30 | 公開日 | 2013-09-18 | 最終更新日 | 2013-10-09 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Bub3 Reads Phosphorylated Melt Repeats to Promote Spindle Assembly Checkpoint Signaling Elife, 2, 2013
|
|
2O2V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2o2v by Molmil](/molmil-images/mine/2o2v) | Crystal Structure of the Complex of Human Mitogen Activated Protein Kinase Kinase 5 Phox Domain (MAP2K5-phox) with Human Mitogen Activated Protein Kinase Kinase Kinase 3 (MAP3K3B-phox) | 分子名称: | Dual specificity mitogen-activated protein kinase kinase 5, Mitogen-activated protein kinase kinase kinase 3 | 著者 | Filippakopoulos, P, Savitsky, P, Ugochukwu, E, Edwards, A, Arrowsmith, C, Sundstrom, M, von Delft, F, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2006-11-30 | 公開日 | 2006-12-12 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Crystal Structure of the Complex of Human Mitogen Activated Protein Kinase Kinase 5 Phox Domain (MAP2K5-phox) with Human Mitogen Activated Protein Kinase Kinase Kinase 3 (MAP3K3B-phox) To be Published
|
|
2O3D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2o3d by Molmil](/molmil-images/mine/2o3d) | Structure of human SF2/ASF RNA recognition motif 2 (RRM2) | 分子名称: | Splicing factor, arginine/serine-rich 1 | 著者 | Tintaru, A.M, Hautbergue, G.M, Hounslow, A.M, Lian, L.Y, Craven, C.J, Wilson, S.A. | 登録日 | 2006-12-01 | 公開日 | 2007-10-16 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural and functional analysis of RNA and TAP binding to SF2/ASF. Embo Rep., 8, 2007
|
|
4BL8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4bl8 by Molmil](/molmil-images/mine/4bl8) | Crystal structure of full-length human Suppressor of fused (SUFU) | 分子名称: | MALTOSE-BINDING PERIPLASMIC PROTEIN, SUPPRESSOR OF FUSED HOMOLOG, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | 著者 | Karlstrom, M, Finta, C, Cherry, A.L, Toftgard, R, Jovine, L. | 登録日 | 2013-05-02 | 公開日 | 2013-11-27 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.04 Å) | 主引用文献 | Structural Basis of Sufu-GLI Interaction in Hedgehog Signalling Regulation Acta Crystallogr.,Sect.D, 69, 2013
|
|
4BLG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4blg by Molmil](/molmil-images/mine/4blg) | Crystal structure of MHV-68 Latency-associated nuclear antigen (LANA) C-terminal DNA binding domain | 分子名称: | LATENCY-ASSOCIATED NUCLEAR ANTIGEN, PHOSPHATE ION | 著者 | Correia, B, Cerqueira, S.A, Beauchemin, C, Pires De Miranda, M, Li, S, Ponnusamy, R, Rodrigues, L, Schneider, T.R, Carrondo, M.A, Kaye, K.M, Simas, J.P, McVey, C.E. | 登録日 | 2013-05-02 | 公開日 | 2013-10-30 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal Structure of the Gamma-2 Herpesvirus Lana DNA Binding Domain Identifies Charged Surface Residues which Impact Viral Latency Plos Pathog., 9, 2013
|
|
4AT4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4at4 by Molmil](/molmil-images/mine/4at4) | CRYSTAL STRUCTURE OF TRKB KINASE DOMAIN IN COMPLEX WITH EX429 | 分子名称: | 1-[4-(4-aminothieno[2,3-d]pyrimidin-5-yl)phenyl]-3-[2-fluoro-5-(trifluoromethyl)phenyl]urea, BDNF/NT-3 GROWTH FACTORS RECEPTOR | 著者 | Bertrand, T, Kothe, M, Liu, J, Dupuy, A, Rak, A, Berne, P.F, Davis, S, Gladysheva, T, Valtre, C, Crenne, J.Y, Mathieu, M. | 登録日 | 2012-05-03 | 公開日 | 2012-08-22 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | 主引用文献 | The Crystal Structures of Trka and Trkb Suggest Key Regions for Achieving Selective Inhibition. J.Mol.Biol., 423, 2012
|
|
4AW0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4aw0 by Molmil](/molmil-images/mine/4aw0) | Human PDK1 Kinase Domain in Complex with Allosteric Compound PS182 Bound to the PIF-Pocket | 分子名称: | 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1, ADENOSINE-5'-TRIPHOSPHATE, DIMETHYL SULFOXIDE, ... | 著者 | Schulze, J.O, Busschots, K, Lopez-Garcia, L.A, Lammi, C, Stroba, A, Zeuzem, S, Piiper, A, Alzari, P.M, Neimanis, S, Arencibia, J.M, Engel, M, Biondi, R.M. | 登録日 | 2012-05-30 | 公開日 | 2012-10-03 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | 主引用文献 | Substrate-Selective Inhibition of Protein Kinase Pdk1 by Small Compounds that Bind to the Pif-Pocket Allosteric Docking Site. Chem.Biol., 19, 2012
|
|
2JED
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2jed by Molmil](/molmil-images/mine/2jed) | The crystal structure of the kinase domain of the protein kinase C theta in complex with NVP-XAA228 at 2.32A resolution. | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 3-(8-DIMETHYLAMINOMETHYL-6,7,8,9-TETRAHYDRO-PYRIDO[1,2-A]INDOL-10-YL)-4-(1-METHYL-1H-INDOL-3-YL)-PYRROLE-2,5-DIONE, PROTEIN KINASE C THETA | 著者 | Stark, W, Bitsch, F, Berner, A, Buelens, F, Graff, P, Depersin, H, Geiser, M, Knecht, R, Rahuel, J, Rummel, G, Schlaeppi, J.M, Schmitz, R, Strauss, A, Wagner, J. | 登録日 | 2007-01-16 | 公開日 | 2008-02-05 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | 主引用文献 | The Crystal Structure of the Kinase Domain of the Protein Kinase C Theta in Complex with Nvp-Xaa228 To be Published
|
|
2JF1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2jf1 by Molmil](/molmil-images/mine/2jf1) | |
4AZF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4azf by Molmil](/molmil-images/mine/4azf) | Human DYRK2 in complex with Leucettine L41 | 分子名称: | 1,2-ETHANEDIOL, 5-(1,3-benzodioxol-5-ylmethyl)-2-(phenylamino)-4H-imidazol-4-one, DYRK2 DUAL-SPECIFICITY TYROSINE-PHOSPHORYLATION REGULATED KINASE 2, ... | 著者 | Elkins, J.M, Soundararajan, M, Muniz, J.R.C, Tahtouh, T, Burgy, G, Durieu, E, Lozach, O, Cochet, C, Schmid, R.S, Lo, D.C, Delhommel, F, Carreaux, F, Bazureau, J.P, Meijer, L, Edwards, A, Bountra, C, Knapp, S. | 登録日 | 2012-06-25 | 公開日 | 2012-09-05 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Selectivity, Co-Crystal Structures and Neuroprotective Properties of Leucettines, a Family of Protein Kinase Inhibitors Derived from the Marine Sponge Alkaloid Leucettamine B. J.Med.Chem., 55, 2012
|
|
4ASI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4asi by Molmil](/molmil-images/mine/4asi) | Crystal structure of human ACACA C-terminal domain | 分子名称: | ACETYL-COA CARBOXYLASE 1 | 著者 | Froese, D.S, Muniz, J.R.C, Kiyani, W, Krojer, T, Vollmar, M, von Delft, F, Bountra, C, Arrowsmith, C.H, Edwards, A, Oppermann, U, Yue, W.W. | 登録日 | 2012-05-01 | 公開日 | 2012-08-29 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal Structure of Human Acaca C-Terminal Domain To be Published
|
|
4ASO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4aso by Molmil](/molmil-images/mine/4aso) | |
2JSM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2jsm by Molmil](/molmil-images/mine/2jsm) | MONOMERIC HUMAN TELOMERE DNA TETRAPLEX WITH 3+1 STRAND FOLD TOPOLOGY, TWO EDGEWISE LOOPS AND DOUBLE-CHAIN REVERSAL LOOP, NMR, 10 STRUCTURES, Form 1 Natural | 分子名称: | HUMAN TELOMERE DNA | 著者 | Kuryavyi, V.V, Phan, A.T, Luu, K.N, Patel, D.J. | 登録日 | 2007-07-09 | 公開日 | 2008-07-08 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of two intramolecular G-quadruplexes formed by natural human telomere sequences in K+ solution Nucleic Acids Res., 35, 2007
|
|
2NTF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ntf by Molmil](/molmil-images/mine/2ntf) | |
4C6V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4c6v by Molmil](/molmil-images/mine/4c6v) | Crystal structure of M. tuberculosis KasA in complex with TLM5 (Soak for 5 min) | 分子名称: | (5R)-3-acetyl-4-hydroxy-5-methyl-5-[(1Z)-2-methylbuta-1,3-dien-1-yl]thiophen-2(5H)-one, 1,2-ETHANEDIOL, 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE 1, ... | 著者 | Schiebel, J, Kapilashrami, K, Fekete, A, Bommineni, G.R, Schaefer, C.M, Mueller, M.J, Tonge, P.J, Kisker, C. | 登録日 | 2013-09-19 | 公開日 | 2013-10-09 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural Basis for the Recognition of Mycolic Acid Precursors by Kasa, a Condensing Enzyme and Drug Target from Mycobacterium Tuberculosis J.Biol.Chem., 288, 2013
|
|
2NV4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2nv4 by Molmil](/molmil-images/mine/2nv4) | Crystal structure of UPF0066 protein AF0241 in complex with S-adenosylmethionine. Northeast Structural Genomics Consortium target GR27 | 分子名称: | ACETATE ION, S-ADENOSYLMETHIONINE, UPF0066 protein AF_0241 | 著者 | Kuzin, A.P, Abashidze, M, Seetharaman, J, Vorobiev, S.M, Fang, Y, Cunningham, K, Ma, L.C, Xiao, R, Liu, J, Baran, M, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2006-11-10 | 公開日 | 2006-11-21 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Functional insights from structural genomics. J.Struct.Funct.Genom., 8, 2007
|
|
2NY2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ny2 by Molmil](/molmil-images/mine/2ny2) | HIV-1 gp120 Envelope Glycoprotein (T123C, T257S, S334A, S375W, G431C) Complexed with CD4 and Antibody 17b | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY 17B, ... | 著者 | Zhou, T, Xu, L, Dey, B, Hessell, A.J, Van Ryk, D, Xiang, S.H, Yang, X, Zhang, M.Y, Zwick, M.B, Arthos, J, Burton, D.R, Dimitrov, D.S, Sodroski, J, Wyatt, R, Nabel, G.J, Kwong, P.D. | 登録日 | 2006-11-20 | 公開日 | 2007-02-06 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural definition of a conserved neutralization epitope on HIV-1 gp120. Nature, 445, 2007
|
|
4BNG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4bng by Molmil](/molmil-images/mine/4bng) | Crystal structure of S. aureus FabI in complex with NADP and 5-pentyl- 2-phenoxyphenol | 分子名称: | 5-PENTYL-2-PHENOXYPHENOL, ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADPH], GLUTAMIC ACID, ... | 著者 | Schiebel, J, Chang, A, Bommineni, G.R, Tonge, P.J, Kisker, C. | 登録日 | 2013-05-15 | 公開日 | 2013-06-05 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Rational Optimization of Drug-Target Residence Time: Insights from Inhibitor Binding to the S. Aureus Fabi Enzyme-Product Complex. Biochemistry, 52, 2013
|
|