6CQO
| Crystal Structure of mitochondrial single-stranded DNA binding proteins from S. cerevisiae (SeMet Labeled), Rim1 (Form2) | 分子名称: | Single-stranded DNA-binding protein RIM1, mitochondrial | 著者 | Singh, S.P, Kukshal, V, Bona, P.D, Lytle, A.K, Edwin, A, Galletto, R. | 登録日 | 2018-03-15 | 公開日 | 2018-05-30 | 最終更新日 | 2020-02-26 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | The mitochondrial single-stranded DNA binding protein from S. cerevisiae, Rim1, does not form stable homo-tetramers and binds DNA as a dimer of dimers. Nucleic Acids Res., 46, 2018
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5YKT
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7KBQ
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4OBC
| Crystal structure of HCV polymerase NS5b genotype 2a JFH-1 isolate with the S15G, C223H, V321I resistance mutations against the guanosine analog GS-0938 (PSI-3529238) | 分子名称: | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ... | 著者 | Edwards, T.E, Abendroth, J, Appleby, T.C. | 登録日 | 2014-01-07 | 公開日 | 2014-09-10 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Molecular and Structural Basis for the Roles of Hepatitis C Virus Polymerase NS5B Amino Acids 15, 223, and 321 in Viral Replication and Drug Resistance. Antimicrob.Agents Chemother., 58, 2014
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6GEI
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2VVO
| Crystal structure of Mycobacterium tuberculosis ribose-5-phosphate isomerase B in complex with alpha d-allose 6-phosphate | 分子名称: | 6-O-phosphono-alpha-D-allopyranose, RIBOSE-5-PHOSPHATE ISOMERASE B | 著者 | Roos, A.K, Mariano, S, Kowalinski, E, Salmon, L, Mowbray, S.L. | 登録日 | 2008-06-10 | 公開日 | 2008-07-01 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | D-Ribose-5-Phosphate Isomerase B from Escherichia Coli is Also a Functional D-Allose-6-Phosphate Isomerase, While the Mycobacterium Tuberculosis Enzyme is not. J.Mol.Biol., 382, 2008
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7KS0
| GluK2/K5 with 6-Cyano-7-nitroquinoxaline-2,3-dione (CNQX) | 分子名称: | Glutamate receptor ionotropic, kainate 2, kainate 5,Green fluorescent protein chimera | 著者 | Khanra, N, Brown, P.M.G.E, Perozzo, A.M, Bowie, D, Meyerson, J.R. | 登録日 | 2020-11-20 | 公開日 | 2021-03-24 | 最終更新日 | 2021-07-07 | 実験手法 | ELECTRON MICROSCOPY (5.3 Å) | 主引用文献 | Architecture and structural dynamics of the heteromeric GluK2/K5 kainate receptor. Elife, 10, 2021
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7KS3
| GluK2/K5 with L-Glu | 分子名称: | Glutamate receptor ionotropic, kainate 2, kainate 5,Green fluorescent protein chimera | 著者 | Khanra, N, Brown, P.M.G.E, Perozzo, A.M, Bowie, D, Meyerson, J.R. | 登録日 | 2020-11-20 | 公開日 | 2021-03-24 | 最終更新日 | 2021-07-07 | 実験手法 | ELECTRON MICROSCOPY (5.8 Å) | 主引用文献 | Architecture and structural dynamics of the heteromeric GluK2/K5 kainate receptor. Elife, 10, 2021
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6WJN
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7P3T
| Transaminase of gamma-proteobacterium | 分子名称: | Branched-chain amino acid aminotransferase, GLYCEROL, PYRIDOXAL-5'-PHOSPHATE | 著者 | Ermler, U. | 登録日 | 2021-07-08 | 公開日 | 2021-12-15 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Rational engineering of Luminiphilus syltensis ( R )-selective amine transaminase for the acceptance of bulky substrates. Chem.Commun.(Camb.), 57, 2021
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2VVP
| Crystal structure of Mycobacterium tuberculosis ribose-5-phosphate isomerase B in complex with its substrates ribose 5-phosphate and ribulose 5-phosphate | 分子名称: | 5-O-phosphono-D-ribose, RIBOSE-5-PHOSPHATE ISOMERASE B, RIBULOSE-5-PHOSPHATE | 著者 | Kowalinski, E, Roos, A.K, Mariano, S, Salmon, L, Mowbray, S.L. | 登録日 | 2008-06-10 | 公開日 | 2008-07-01 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | D-Ribose-5-Phosphate Isomerase B from Escherichia Coli is Also a Functional D-Allose-6-Phosphate Isomerase, While the Mycobacterium Tuberculosis Enzyme is not. J.Mol.Biol., 382, 2008
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6WGI
| Atomic model of the mutant OCCM (ORC-Cdc6-Cdt1-Mcm2-7 with Mcm6 WHD truncation) loaded on DNA at 10.5 A resolution | 分子名称: | Cell division control protein 6, Cell division cycle protein CDT1, DNA (34-MER), ... | 著者 | Yuan, Z, Schneider, S, Dodd, T, Riera, A, Bai, L, Yan, C, Magdalou, I, Ivanov, I, Stillman, B, Li, H, Speck, C. | 登録日 | 2020-04-05 | 公開日 | 2020-07-15 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (10 Å) | 主引用文献 | Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6. Proc.Natl.Acad.Sci.USA, 117, 2020
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5DEX
| Crystal structure of GluN1/GluN2A NMDA receptor agonist binding domains with glycine and antagonist, phenyl-ACEPC | 分子名称: | 5-[(2R)-2-amino-2-carboxyethyl]-1-phenyl-1H-pyrazole-3-carboxylic acid, GLYCINE, Glutamate receptor ionotropic, ... | 著者 | Mou, T.-C, Conti, P, Pinto, A, Tamborini, L, Sprang, S.R, Hansen, K.B. | 登録日 | 2015-08-26 | 公開日 | 2016-09-14 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural basis of subunit selectivity for competitive NMDA receptor antagonists with preference for GluN2A over GluN2B subunits. Proc. Natl. Acad. Sci. U.S.A., 2017
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6WJD
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6LX1
| Potato D-enzyme complexed with Acarbose | 分子名称: | 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-1,5-anhydro-D-glucitol, 4-alpha-glucanotransferase, chloroplastic/amyloplastic, ... | 著者 | Unno, H, Imamura, K. | 登録日 | 2020-02-10 | 公開日 | 2020-08-26 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Structural analysis and reaction mechanism of the disproportionating enzyme (D-enzyme) from potato. Protein Sci., 29, 2020
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7SAB
| Phencyclidine-bound GluN1a-GluN2B NMDA receptors | 分子名称: | 1-(PHENYL-1-CYCLOHEXYL)PIPERIDINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Chou, T.-H, Furukawa, H. | 登録日 | 2021-09-22 | 公開日 | 2022-07-20 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Structural insights into binding of therapeutic channel blockers in NMDA receptors. Nat.Struct.Mol.Biol., 29, 2022
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7SAD
| Memantine-bound GluN1a-GluN2B NMDA receptors | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... | 著者 | Chou, T.-H, Furukawa, H. | 登録日 | 2021-09-22 | 公開日 | 2022-07-20 | 実験手法 | ELECTRON MICROSCOPY (3.96 Å) | 主引用文献 | Structural insights into binding of therapeutic channel blockers in NMDA receptors. Nat.Struct.Mol.Biol., 29, 2022
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7SAA
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7SAC
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2VVQ
| Crystal structure of Mycobacterium tuberculosis ribose-5-phosphate isomerase B in complex with the inhibitor 5-deoxy-5-phospho-D- ribonate | 分子名称: | 5-O-phosphono-D-ribonic acid, RIBOSE-5-PHOSPHATE ISOMERASE B, SULFATE ION | 著者 | Kowalinski, E, Roos, A.K, Mariano, S, Salmon, L, Mowbray, S.L. | 登録日 | 2008-06-10 | 公開日 | 2008-07-01 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | D-Ribose-5-Phosphate Isomerase B from Escherichia Coli is Also a Functional D-Allose-6-Phosphate Isomerase, While the Mycobacterium Tuberculosis Enzyme is not. J.Mol.Biol., 382, 2008
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4CAA
| CLEAVED ANTICHYMOTRYPSIN T345R | 分子名称: | ANTICHYMOTRYPSIN | 著者 | Lukacs, C.M, Christianson, D.W. | 登録日 | 1997-08-14 | 公開日 | 1998-02-25 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Engineering an anion-binding cavity in antichymotrypsin modulates the "spring-loaded" serpin-protease interaction. Biochemistry, 37, 1998
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2BJF
| Crystal Structure of Conjugated Bile Acid Hydrolase from Clostridium perfringens in Complex with Reaction Products Taurine and Deoxycholate | 分子名称: | (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, 2-AMINOETHANESULFONIC ACID, CHOLOYLGLYCINE HYDROLASE, ... | 著者 | Rossocha, M, Schultz-Heienbrok, R, Von Moeller, H, Coleman, J.P, Saenger, W. | 登録日 | 2005-02-02 | 公開日 | 2005-03-03 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | Conjugated Bile Acid Hydrolase is a Tetrameric N-Terminal Thiol Hydrolase with Specific Recognition of its Cholyl But not of its Tauryl Product Biochemistry, 44, 2005
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8FR3
| E. coli EF-Tu in complex with KKL-55 | 分子名称: | 3-chloro-N-(1-propyl-1H-tetrazol-5-yl)benzamide, Elongation factor Tu, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Nguyen, H.A, Kuzmishin Nagy, A.B, Dunham, C.M. | 登録日 | 2023-01-06 | 公開日 | 2023-09-20 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | 主引用文献 | Antibiotic that inhibits trans -translation blocks binding of EF-Tu to tmRNA but not to tRNA. Mbio, 14, 2023
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8AHW
| Structure of DCS-resistant variant D322N of alanine racemase from Mycobacterium tuberculosis | 分子名称: | 1,2-ETHANEDIOL, Alanine racemase, GLYCEROL | 著者 | de Chiara, C, Prosser, G, Ogrodowicz, R.W, de Carvalho, L.P.S. | 登録日 | 2022-07-22 | 公開日 | 2023-04-05 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | 主引用文献 | Structure of the d-Cycloserine-Resistant Variant D322N of Alanine Racemase from Mycobacterium tuberculosis . Acs Bio Med Chem Au, 3, 2023
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6U59
| HIV-1 B41 SOSIP.664 in complex with rabbit antibody 13B | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SOSIP.664 gp120,SOSIP.664 gp120, ... | 著者 | Yang, Y.R, Ward, A.B. | 登録日 | 2019-08-27 | 公開日 | 2020-01-29 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.86 Å) | 主引用文献 | Autologous Antibody Responses to an HIV Envelope Glycan Hole Are Not Easily Broadened in Rabbits. J.Virol., 94, 2020
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