4IVE
| |
4YVV
| Crystal structure of AKR1C3 complexed with glibenclamide | 分子名称: | 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, Aldo-keto reductase family 1 member C3, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Zhao, Y, Zheng, X, Zhang, H, Hu, X. | 登録日 | 2015-03-20 | 公開日 | 2015-11-25 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | In vitro inhibition of AKR1Cs by sulphonylureas and the structural basis Chem.Biol.Interact., 240, 2015
|
|
4YVX
| Crystal structure of AKR1C3 complexed with glimepiride | 分子名称: | 3-ethyl-4-methyl-N-[2-(4-{[(cis-4-methylcyclohexyl)carbamoyl]sulfamoyl}phenyl)ethyl]-2-oxo-2,5-dihydro-1H-pyrrole-1-car boxamide, Aldo-keto reductase family 1 member C3, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Zhao, Y, Zheng, X, Zhang, H, Hu, X. | 登録日 | 2015-03-20 | 公開日 | 2015-11-25 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | In vitro inhibition of AKR1Cs by sulphonylureas and the structural basis Chem.Biol.Interact., 240, 2015
|
|
4K0A
| |
5HHX
| |
5HIW
| Sorangium cellulosum So Ce56 cytochrome P450 260B1 | 分子名称: | Cytochrome P450 CYP260B1, MAGNESIUM ION, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Salamanca-Pinzon, S.G, Carius, Y, Khatri, Y, Bernhardt, R, Lancaster, C.R.D. | 登録日 | 2016-01-12 | 公開日 | 2016-08-03 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structure-function analysis for the hydroxylation of Delta 4 C21-steroids by the myxobacterial CYP260B1. Febs Lett., 590, 2016
|
|
2RR4
| Complex structure of the zf-CW domain and the H3K4me3 peptide | 分子名称: | Histone H3, ZINC ION, Zinc finger CW-type PWWP domain protein 1 | 著者 | He, F, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2010-03-24 | 公開日 | 2010-09-15 | 最終更新日 | 2011-07-13 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural insight into the zinc finger CW domain as a histone modification reader Structure, 18, 2010
|
|
4K3V
| Structure of Staphylococcus aureus MntC | 分子名称: | ABC superfamily ATP binding cassette transporter, binding protein, MANGANESE (II) ION | 著者 | Parris, K.D, Mosyak, L. | 登録日 | 2013-04-11 | 公開日 | 2013-07-17 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Three-Dimensional Structure and Biophysical Characterization of Staphylococcus aureus Cell Surface Antigen-Manganese Transporter MntC. J.Mol.Biol., 425, 2013
|
|
5HQX
| Crystal structure of maize cytokinin oxidase/dehydrogenase 4 (ZmCKO4) in complex with phenylurea inhibitor HETDZ | 分子名称: | 1-[2-(2-hydroxyethyl)phenyl]-3-(1,2,3-thiadiazol-5-yl)urea, Cytokinin dehydrogenase 4, FLAVIN-ADENINE DINUCLEOTIDE | 著者 | Kopecny, D, Koncitikova, R, Briozzo, P. | 登録日 | 2016-01-22 | 公開日 | 2016-07-27 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Novel thidiazuron-derived inhibitors of cytokinin oxidase/dehydrogenase. Plant Mol.Biol., 92, 2016
|
|
1EQU
| TYPE 1 17-BETA HYDROXYSTEROID DEHYDROGENASE EQUILIN COMPLEXED WITH NADP+ | 分子名称: | EQUILIN, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PROTEIN (ESTRADIOL 17 BETA-DEHYDROGENASE 1) | 著者 | Sawicki, M.W, Erman, M, Puranen, T, Vihko, P, Ghosh, D. | 登録日 | 1998-12-02 | 公開日 | 1999-12-02 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structure of the ternary complex of human 17beta-hydroxysteroid dehydrogenase type 1 with 3-hydroxyestra-1,3,5,7-tetraen-17-one (equilin) and NADP+. Proc.Natl.Acad.Sci.USA, 96, 1999
|
|
5HV9
| Human LTC4S mutant-S36E | 分子名称: | GLUTATHIONE, Leukotriene C4 synthase, SULFATE ION | 著者 | Thulasingam, M, Ahmad, H.R.S, Rinaldo-Matthis, A, Haeggstrom, J.Z. | 登録日 | 2016-01-28 | 公開日 | 2016-07-13 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Phosphorylation of Leukotriene C4 Synthase at Serine 36 Impairs Catalytic Activity. J.Biol.Chem., 291, 2016
|
|
5HWE
| high resolution structure of barbiturase | 分子名称: | (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, Barbiturase, MAGNESIUM ION, ... | 著者 | Peat, T.S, Scott, C. | 登録日 | 2016-01-29 | 公開日 | 2017-02-01 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | 主引用文献 | High-Resolution X-Ray Structures of Two Functionally Distinct Members of the Cyclic Amide Hydrolase Family of Toblerone Fold Enzymes. Appl. Environ. Microbiol., 83, 2017
|
|
5HY2
| Structure-function analysis of functionally diverse members of the cyclic amide hydrolase family of Toblerone fold enzymes | 分子名称: | Ring-opening amidohydrolase | 著者 | Peat, T.S, Balotra, S, Wilding, M, Newman, J, Scott, C. | 登録日 | 2016-02-01 | 公開日 | 2017-02-01 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | High-Resolution X-Ray Structures of Two Functionally Distinct Members of the Cyclic Amide Hydrolase Family of Toblerone Fold Enzymes. Appl. Environ. Microbiol., 83, 2017
|
|
5HXZ
| Structure-function analysis of functionally diverse members of the cyclic amide hydrolase family of Toblerone fold enzymes | 分子名称: | (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, Barbiturase, CHLORIDE ION, ... | 著者 | Peat, T.S, Balotra, S, Wilding, M, Newman, J, Scott, C. | 登録日 | 2016-01-31 | 公開日 | 2017-02-01 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | 主引用文献 | High-Resolution X-Ray Structures of Two Functionally Distinct Members of the Cyclic Amide Hydrolase Family of Toblerone Fold Enzymes. Appl. Environ. Microbiol., 83, 2017
|
|
5HXU
| Structure-function analysis of functionally diverse members of the cyclic amide hydrolase family of Toblerone fold enzymes | 分子名称: | (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, Barbiturase, CHLORIDE ION, ... | 著者 | Peat, T.S, Balotra, S, Wilding, M, Newman, J, Scott, C. | 登録日 | 2016-01-31 | 公開日 | 2017-02-01 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | High-Resolution X-Ray Structures of Two Functionally Distinct Members of the Cyclic Amide Hydrolase Family of Toblerone Fold Enzymes. Appl. Environ. Microbiol., 83, 2017
|
|
5HY1
| high resolution structure of barbiturase | 分子名称: | 1,3,5-triazine-2,4,6-triol, Barbiturase, CHLORIDE ION, ... | 著者 | Peat, T.S, Scott, C, Balotra, S, Wilding, M, Newman, J. | 登録日 | 2016-02-01 | 公開日 | 2017-02-01 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | High-Resolution X-Ray Structures of Two Functionally Distinct Members of the Cyclic Amide Hydrolase Family of Toblerone Fold Enzymes. Appl. Environ. Microbiol., 83, 2017
|
|
4KF5
| Crystal Structure of Split GFP complexed with engineered sfCherry with an insertion of GFP fragment | 分子名称: | fluorescent protein GFP1-9, fluorescent protein sfCherry+GFP10-11 | 著者 | Nguyen, H.B, Hung, L.-W, Yeates, T.O, Waldo, G.S, Terwilliger, T.C. | 登録日 | 2013-04-26 | 公開日 | 2013-12-18 | 実験手法 | X-RAY DIFFRACTION (2.599 Å) | 主引用文献 | Split green fluorescent protein as a modular binding partner for protein crystallization. Acta Crystallogr.,Sect.D, 69, 2013
|
|
5I2E
| Human Histidine Triad Nucleotide Binding Protein 1 (Hint1) with Bound Sulfamate Inhibitor 3a:3-(5-O-{[3-(1H-indol-3-yl)propanoyl]sulfamoyl}-beta-D-ribofuranosyl)-3H-imidazo[2,1-i]purine | 分子名称: | 3-(5-O-{[3-(1H-indol-3-yl)propanoyl]sulfamoyl}-beta-D-ribofuranosyl)-3H-imidazo[2,1-i]purine, GLYCEROL, Histidine triad nucleotide-binding protein 1 | 著者 | Strom, A.M, Finzel, B.C, Wagner, C.R. | 登録日 | 2016-02-08 | 公開日 | 2016-06-22 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Design, Synthesis, and Characterization of Sulfamide and Sulfamate Nucleotidomimetic Inhibitors of hHint1. Acs Med.Chem.Lett., 7, 2016
|
|
5I2A
| 1,2-propanediol Dehydration in Roseburia inulinivorans; Structural Basis for Substrate and Enantiomer Selectivity | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Diol-dehydratase | 著者 | LaMattina, J.W, Reitzer, P, Kapoor, S, Galzerani, F, Koch, D.J, Gouvea, I.E, Lanzilotta, W.N. | 登録日 | 2016-02-08 | 公開日 | 2016-06-01 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | 1,2-Propanediol Dehydration in Roseburia inulinivorans: STRUCTURAL BASIS FOR SUBSTRATE AND ENANTIOMER SELECTIVITY. J.Biol.Chem., 291, 2016
|
|
5T0G
| Structural basis for dynamic regulation of the human 26S proteasome | 分子名称: | 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ... | 著者 | Chen, S, Wu, J, Lu, Y, Ma, Y.B, Lee, B.H, Yu, Z, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y. | 登録日 | 2016-08-16 | 公開日 | 2016-10-19 | 最終更新日 | 2016-11-30 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Structural basis for dynamic regulation of the human 26S proteasome. Proc.Natl.Acad.Sci.USA, 113, 2016
|
|
4KF4
| Crystal Structure of sfCherry | 分子名称: | fluorescent protein sfCherry | 著者 | Nguyen, H.B, Hung, L.-W, Yeates, T.O, Waldo, G.S, Terwilliger, T.C. | 登録日 | 2013-04-26 | 公開日 | 2013-12-18 | 実験手法 | X-RAY DIFFRACTION (1.994 Å) | 主引用文献 | Split green fluorescent protein as a modular binding partner for protein crystallization. Acta Crystallogr.,Sect.D, 69, 2013
|
|
5I2F
| Human Histidine Triad Nucleotide Binding Protein 1 (hHint1) with bound sulfamide inhibitor Bio-AMS | 分子名称: | 1,2-ETHANEDIOL, 5'-deoxy-5'-[({5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}sulfamoyl)amino]adenosine, Histidine triad nucleotide-binding protein 1 | 著者 | Maize, K.M, Finzel, B.C. | 登録日 | 2016-02-08 | 公開日 | 2016-06-22 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Design, Synthesis, and Characterization of Sulfamide and Sulfamate Nucleotidomimetic Inhibitors of hHint1. Acs Med.Chem.Lett., 7, 2016
|
|
4KJY
| Complex of high-affinity SIRP alpha variant FD6 with CD47 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, High-affinity SIRPa variant FD6, Leukocyte surface antigen CD47, ... | 著者 | Ring, A.M, Ozkan, E, Ho, C.C.M, Garcia, K.C. | 登録日 | 2013-05-04 | 公開日 | 2013-06-12 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Engineered SIRP alpha variants as immunotherapeutic adjuvants to anticancer antibodies. Science, 341, 2013
|
|
5I8F
| Crystal structure of St. John's wort Hyp-1 protein in complex with melatonin | 分子名称: | GLYCEROL, N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide, Phenolic oxidative coupling protein, ... | 著者 | Sliwiak, J, Dauter, Z, Jaskolski, M. | 登録日 | 2016-02-18 | 公開日 | 2016-05-25 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Crystal Structure of Hyp-1, a Hypericum perforatum PR-10 Protein, in Complex with Melatonin. Front Plant Sci, 7, 2016
|
|
4KM4
| |