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4IVE
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Crystal structure of a polyadenylate-binding protein 3 (PABPC3) from Homo sapiens at 2.30 A resolution
分子名称: CHLORIDE ION, Polyadenylate-binding protein 3
著者Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL)
登録日2013-01-22
公開日2013-02-06
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of a polyadenylate-binding protein 3 (PABPC3) from Homo sapiens at 2.30 A resolution
To be published
4YVV
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BU of 4yvv by Molmil
Crystal structure of AKR1C3 complexed with glibenclamide
分子名称: 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, Aldo-keto reductase family 1 member C3, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Zhao, Y, Zheng, X, Zhang, H, Hu, X.
登録日2015-03-20
公開日2015-11-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献In vitro inhibition of AKR1Cs by sulphonylureas and the structural basis
Chem.Biol.Interact., 240, 2015
4YVX
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BU of 4yvx by Molmil
Crystal structure of AKR1C3 complexed with glimepiride
分子名称: 3-ethyl-4-methyl-N-[2-(4-{[(cis-4-methylcyclohexyl)carbamoyl]sulfamoyl}phenyl)ethyl]-2-oxo-2,5-dihydro-1H-pyrrole-1-car boxamide, Aldo-keto reductase family 1 member C3, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Zhao, Y, Zheng, X, Zhang, H, Hu, X.
登録日2015-03-20
公開日2015-11-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献In vitro inhibition of AKR1Cs by sulphonylureas and the structural basis
Chem.Biol.Interact., 240, 2015
4K0A
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BU of 4k0a by Molmil
Crystal structure of CD4-mimetic miniprotein M48U7 in complex with HIV-1 YU2 gp120
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CD4-MIMETIC MINIPROTEIN M48U7, CITRATE ANION, ...
著者Acharya, P, Kwong, P.D.
登録日2013-04-03
公開日2013-06-12
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Structural Basis for Highly Effective HIV-1 Neutralization by CD4-Mimetic Miniproteins Revealed by 1.5 A Cocrystal Structure of gp120 and M48U1.
Structure, 21, 2013
5HHX
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BU of 5hhx by Molmil
Inhibiting complex IL-17A and IL-17RA interactions with a linear peptide
分子名称: CAT-2000 FAB heavy chain, CAT-2000 FAB light chain, IL-17A peptide inhibitor, ...
著者Liu, S.
登録日2016-01-11
公開日2016-06-01
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Inhibiting complex IL-17A and IL-17RA interactions with a linear peptide.
Sci Rep, 6, 2016
5HIW
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BU of 5hiw by Molmil
Sorangium cellulosum So Ce56 cytochrome P450 260B1
分子名称: Cytochrome P450 CYP260B1, MAGNESIUM ION, PROTOPORPHYRIN IX CONTAINING FE
著者Salamanca-Pinzon, S.G, Carius, Y, Khatri, Y, Bernhardt, R, Lancaster, C.R.D.
登録日2016-01-12
公開日2016-08-03
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structure-function analysis for the hydroxylation of Delta 4 C21-steroids by the myxobacterial CYP260B1.
Febs Lett., 590, 2016
2RR4
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BU of 2rr4 by Molmil
Complex structure of the zf-CW domain and the H3K4me3 peptide
分子名称: Histone H3, ZINC ION, Zinc finger CW-type PWWP domain protein 1
著者He, F, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2010-03-24
公開日2010-09-15
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structural insight into the zinc finger CW domain as a histone modification reader
Structure, 18, 2010
4K3V
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BU of 4k3v by Molmil
Structure of Staphylococcus aureus MntC
分子名称: ABC superfamily ATP binding cassette transporter, binding protein, MANGANESE (II) ION
著者Parris, K.D, Mosyak, L.
登録日2013-04-11
公開日2013-07-17
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Three-Dimensional Structure and Biophysical Characterization of Staphylococcus aureus Cell Surface Antigen-Manganese Transporter MntC.
J.Mol.Biol., 425, 2013
5HQX
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BU of 5hqx by Molmil
Crystal structure of maize cytokinin oxidase/dehydrogenase 4 (ZmCKO4) in complex with phenylurea inhibitor HETDZ
分子名称: 1-[2-(2-hydroxyethyl)phenyl]-3-(1,2,3-thiadiazol-5-yl)urea, Cytokinin dehydrogenase 4, FLAVIN-ADENINE DINUCLEOTIDE
著者Kopecny, D, Koncitikova, R, Briozzo, P.
登録日2016-01-22
公開日2016-07-27
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Novel thidiazuron-derived inhibitors of cytokinin oxidase/dehydrogenase.
Plant Mol.Biol., 92, 2016
1EQU
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BU of 1equ by Molmil
TYPE 1 17-BETA HYDROXYSTEROID DEHYDROGENASE EQUILIN COMPLEXED WITH NADP+
分子名称: EQUILIN, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PROTEIN (ESTRADIOL 17 BETA-DEHYDROGENASE 1)
著者Sawicki, M.W, Erman, M, Puranen, T, Vihko, P, Ghosh, D.
登録日1998-12-02
公開日1999-12-02
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of the ternary complex of human 17beta-hydroxysteroid dehydrogenase type 1 with 3-hydroxyestra-1,3,5,7-tetraen-17-one (equilin) and NADP+.
Proc.Natl.Acad.Sci.USA, 96, 1999
5HV9
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BU of 5hv9 by Molmil
Human LTC4S mutant-S36E
分子名称: GLUTATHIONE, Leukotriene C4 synthase, SULFATE ION
著者Thulasingam, M, Ahmad, H.R.S, Rinaldo-Matthis, A, Haeggstrom, J.Z.
登録日2016-01-28
公開日2016-07-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Phosphorylation of Leukotriene C4 Synthase at Serine 36 Impairs Catalytic Activity.
J.Biol.Chem., 291, 2016
5HWE
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BU of 5hwe by Molmil
high resolution structure of barbiturase
分子名称: (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, Barbiturase, MAGNESIUM ION, ...
著者Peat, T.S, Scott, C.
登録日2016-01-29
公開日2017-02-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献High-Resolution X-Ray Structures of Two Functionally Distinct Members of the Cyclic Amide Hydrolase Family of Toblerone Fold Enzymes.
Appl. Environ. Microbiol., 83, 2017
5HY2
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BU of 5hy2 by Molmil
Structure-function analysis of functionally diverse members of the cyclic amide hydrolase family of Toblerone fold enzymes
分子名称: Ring-opening amidohydrolase
著者Peat, T.S, Balotra, S, Wilding, M, Newman, J, Scott, C.
登録日2016-02-01
公開日2017-02-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献High-Resolution X-Ray Structures of Two Functionally Distinct Members of the Cyclic Amide Hydrolase Family of Toblerone Fold Enzymes.
Appl. Environ. Microbiol., 83, 2017
5HXZ
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BU of 5hxz by Molmil
Structure-function analysis of functionally diverse members of the cyclic amide hydrolase family of Toblerone fold enzymes
分子名称: (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, Barbiturase, CHLORIDE ION, ...
著者Peat, T.S, Balotra, S, Wilding, M, Newman, J, Scott, C.
登録日2016-01-31
公開日2017-02-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献High-Resolution X-Ray Structures of Two Functionally Distinct Members of the Cyclic Amide Hydrolase Family of Toblerone Fold Enzymes.
Appl. Environ. Microbiol., 83, 2017
5HXU
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BU of 5hxu by Molmil
Structure-function analysis of functionally diverse members of the cyclic amide hydrolase family of Toblerone fold enzymes
分子名称: (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, Barbiturase, CHLORIDE ION, ...
著者Peat, T.S, Balotra, S, Wilding, M, Newman, J, Scott, C.
登録日2016-01-31
公開日2017-02-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献High-Resolution X-Ray Structures of Two Functionally Distinct Members of the Cyclic Amide Hydrolase Family of Toblerone Fold Enzymes.
Appl. Environ. Microbiol., 83, 2017
5HY1
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BU of 5hy1 by Molmil
high resolution structure of barbiturase
分子名称: 1,3,5-triazine-2,4,6-triol, Barbiturase, CHLORIDE ION, ...
著者Peat, T.S, Scott, C, Balotra, S, Wilding, M, Newman, J.
登録日2016-02-01
公開日2017-02-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献High-Resolution X-Ray Structures of Two Functionally Distinct Members of the Cyclic Amide Hydrolase Family of Toblerone Fold Enzymes.
Appl. Environ. Microbiol., 83, 2017
4KF5
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BU of 4kf5 by Molmil
Crystal Structure of Split GFP complexed with engineered sfCherry with an insertion of GFP fragment
分子名称: fluorescent protein GFP1-9, fluorescent protein sfCherry+GFP10-11
著者Nguyen, H.B, Hung, L.-W, Yeates, T.O, Waldo, G.S, Terwilliger, T.C.
登録日2013-04-26
公開日2013-12-18
実験手法X-RAY DIFFRACTION (2.599 Å)
主引用文献Split green fluorescent protein as a modular binding partner for protein crystallization.
Acta Crystallogr.,Sect.D, 69, 2013
5I2E
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BU of 5i2e by Molmil
Human Histidine Triad Nucleotide Binding Protein 1 (Hint1) with Bound Sulfamate Inhibitor 3a:3-(5-O-{[3-(1H-indol-3-yl)propanoyl]sulfamoyl}-beta-D-ribofuranosyl)-3H-imidazo[2,1-i]purine
分子名称: 3-(5-O-{[3-(1H-indol-3-yl)propanoyl]sulfamoyl}-beta-D-ribofuranosyl)-3H-imidazo[2,1-i]purine, GLYCEROL, Histidine triad nucleotide-binding protein 1
著者Strom, A.M, Finzel, B.C, Wagner, C.R.
登録日2016-02-08
公開日2016-06-22
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Design, Synthesis, and Characterization of Sulfamide and Sulfamate Nucleotidomimetic Inhibitors of hHint1.
Acs Med.Chem.Lett., 7, 2016
5I2A
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BU of 5i2a by Molmil
1,2-propanediol Dehydration in Roseburia inulinivorans; Structural Basis for Substrate and Enantiomer Selectivity
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Diol-dehydratase
著者LaMattina, J.W, Reitzer, P, Kapoor, S, Galzerani, F, Koch, D.J, Gouvea, I.E, Lanzilotta, W.N.
登録日2016-02-08
公開日2016-06-01
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献1,2-Propanediol Dehydration in Roseburia inulinivorans: STRUCTURAL BASIS FOR SUBSTRATE AND ENANTIOMER SELECTIVITY.
J.Biol.Chem., 291, 2016
5T0G
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BU of 5t0g by Molmil
Structural basis for dynamic regulation of the human 26S proteasome
分子名称: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ...
著者Chen, S, Wu, J, Lu, Y, Ma, Y.B, Lee, B.H, Yu, Z, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y.
登録日2016-08-16
公開日2016-10-19
最終更新日2016-11-30
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Structural basis for dynamic regulation of the human 26S proteasome.
Proc.Natl.Acad.Sci.USA, 113, 2016
4KF4
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Crystal Structure of sfCherry
分子名称: fluorescent protein sfCherry
著者Nguyen, H.B, Hung, L.-W, Yeates, T.O, Waldo, G.S, Terwilliger, T.C.
登録日2013-04-26
公開日2013-12-18
実験手法X-RAY DIFFRACTION (1.994 Å)
主引用文献Split green fluorescent protein as a modular binding partner for protein crystallization.
Acta Crystallogr.,Sect.D, 69, 2013
5I2F
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Human Histidine Triad Nucleotide Binding Protein 1 (hHint1) with bound sulfamide inhibitor Bio-AMS
分子名称: 1,2-ETHANEDIOL, 5'-deoxy-5'-[({5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}sulfamoyl)amino]adenosine, Histidine triad nucleotide-binding protein 1
著者Maize, K.M, Finzel, B.C.
登録日2016-02-08
公開日2016-06-22
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Design, Synthesis, and Characterization of Sulfamide and Sulfamate Nucleotidomimetic Inhibitors of hHint1.
Acs Med.Chem.Lett., 7, 2016
4KJY
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Complex of high-affinity SIRP alpha variant FD6 with CD47
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, High-affinity SIRPa variant FD6, Leukocyte surface antigen CD47, ...
著者Ring, A.M, Ozkan, E, Ho, C.C.M, Garcia, K.C.
登録日2013-05-04
公開日2013-06-12
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Engineered SIRP alpha variants as immunotherapeutic adjuvants to anticancer antibodies.
Science, 341, 2013
5I8F
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BU of 5i8f by Molmil
Crystal structure of St. John's wort Hyp-1 protein in complex with melatonin
分子名称: GLYCEROL, N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide, Phenolic oxidative coupling protein, ...
著者Sliwiak, J, Dauter, Z, Jaskolski, M.
登録日2016-02-18
公開日2016-05-25
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Crystal Structure of Hyp-1, a Hypericum perforatum PR-10 Protein, in Complex with Melatonin.
Front Plant Sci, 7, 2016
4KM4
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E. coli alkaline phosphatase mutant S102G/R166S in complex with inorganic phosphate
分子名称: Alkaline phosphatase, PHOSPHATE ION, ZINC ION
著者Andrews, L.D, Fenn, T.D, Herschlag, D.
登録日2013-05-08
公開日2013-07-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Ground state destabilization by anionic nucleophiles contributes to the activity of phosphoryl transfer enzymes.
Plos Biol., 11, 2013

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