1EQU
TYPE 1 17-BETA HYDROXYSTEROID DEHYDROGENASE EQUILIN COMPLEXED WITH NADP+
Summary for 1EQU
Entry DOI | 10.2210/pdb1equ/pdb |
Descriptor | PROTEIN (ESTRADIOL 17 BETA-DEHYDROGENASE 1), NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, EQUILIN, ... (4 entities in total) |
Functional Keywords | hydroxysteroid dehydrogenase, short chain dehydrogenase, reductase, oxidoreductase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P14061 |
Total number of polymer chains | 2 |
Total formula weight | 71530.82 |
Authors | Sawicki, M.W.,Erman, M.,Puranen, T.,Vihko, P.,Ghosh, D. (deposition date: 1998-12-02, release date: 1999-12-02, Last modification date: 2023-08-09) |
Primary citation | Sawicki, M.W.,Erman, M.,Puranen, T.,Vihko, P.,Ghosh, D. Structure of the ternary complex of human 17beta-hydroxysteroid dehydrogenase type 1 with 3-hydroxyestra-1,3,5,7-tetraen-17-one (equilin) and NADP+. Proc.Natl.Acad.Sci.USA, 96:840-845, 1999 Cited by PubMed: 9927655DOI: 10.1073/pnas.96.3.840 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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