PDB: 222415 件ウェブページステータス検索Chemie searchBIRD

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5SPS	PanDDA analysis group deposition -- Crystal structure of SARS-CoV-2 NSP3 macrodomain in complex with FRESH00012962804 - (S) isomer 分子名称: (3S)-6,6-dimethyl-1-(7H-pyrrolo[2,3-d]pyrimidine-4-carbonyl)piperidine-3-carboxylic acid, Non-structural protein 3 著者 Correy, G.J, Fraser, J.S. 登録日 2022-06-09 公開日 2022-07-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.05 Å) 主引用文献 Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 120, 2023
5SPV	PanDDA analysis group deposition -- Crystal structure of SARS-CoV-2 NSP3 macrodomain in complex with REAL250003774401 分子名称: 2-[methyl-[(9-oxidanylidene-1$l^{4},7,8-triazabicyclo[4.3.0]nona-1(6),2,4-trien-3-yl)carbonyl]amino]ethanoic acid, Non-structural protein 3 著者 Correy, G.J, Fraser, J.S. 登録日 2022-06-09 公開日 2022-07-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.05 Å) 主引用文献 Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 120, 2023
5SPQ	PanDDA analysis group deposition -- Crystal structure of SARS-CoV-2 NSP3 macrodomain in complex with FRESH00014134848 - (R) isomer 分子名称: (3R)-1-[(4-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)acetyl]-3-methylpyrrolidine-3-carboxylic acid, Non-structural protein 3 著者 Correy, G.J, Fraser, J.S. 登録日 2022-06-09 公開日 2022-07-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.05 Å) 主引用文献 Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 120, 2023
5SPW	PanDDA analysis group deposition -- Crystal structure of SARS-CoV-2 NSP3 macrodomain in complex with FRESH00004674769 - (R,S,R) isomer 分子名称: (1R,5S,6R)-3-(7H-purin-6-yl)-3-azabicyclo[3.2.2]nonane-6-carboxylic acid, Non-structural protein 3 著者 Correy, G.J, Fraser, J.S. 登録日 2022-06-09 公開日 2022-07-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.05 Å) 主引用文献 Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 120, 2023
3F6N	Crystal structure of the virion-associated protein P3 from Caulimovirus 分子名称: Virion-associated protein 著者 Hoh, F, Uzest, M, Blanc, S, Dumas, C. 登録日 2008-11-06 公開日 2009-11-24 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural insights into the molecular mechanisms of cauliflower mosaic virus transmission by its insect vector. J.Virol., 84, 2010
3EZH	Crystal Structure of the E. coli Histidine Kinase NarX Sensor Domain in Complex with Nitrate 分子名称: NITRATE ION, Nitrate/nitrite sensor protein narX 著者 Cheung, J, Hendrickson, W.A. 登録日 2008-10-22 公開日 2008-12-23 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural Analysis of Ligand Stimulation of the Histidine Kinase NarX. Structure, 17, 2009
3F8C	Crystal structure of multidrug binding transcriptional regulator LmrR complexed with Hoechst 33342 分子名称: 2'-(4-ETHOXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE, Transcriptional regulator, PadR-like family 著者 Madoori, P.K, Agustiandari, H, Driessen, A.J.M, Thunnissen, A.-M.W.H. 登録日 2008-11-12 公開日 2008-12-30 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure of the transcriptional regulator LmrR and its mechanism of multidrug recognition. Embo J., 28, 2009
2RFX	Crystal Structure of HLA-B*5701, presenting the self peptide, LSSPVTKSF 分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... 著者 Archbold, J.K, Macdonald, W.A, Rossjohn, J, McCluskey, J. 登録日 2007-10-02 公開日 2008-07-08 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Human leukocyte antigen class I-restricted activation of CD8+ T cells provides the immunogenetic basis of a systemic drug hypersensitivity Immunity, 28, 2008
2RGI	Crystal structure of Ca2+-free S100A2 at 1.6 A resolution 分子名称: ISOPROPYL ALCOHOL, Protein S100-A2, SODIUM ION 著者 Koch, M, Diez, J, Fritz, G. 登録日 2007-10-03 公開日 2008-01-29 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structure of Ca2+ -free S100A2 at 1.6-A resolution. J.Mol.Biol., 378, 2008
2RGR	Topoisomerase IIA bound to G-segment DNA 分子名称: DNA, DNA topoisomerase 2, MAGNESIUM ION 著者 Dong, K.C, Berger, J.M. 登録日 2007-10-04 公開日 2007-12-25 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural basis for gate-DNA recognition and bending by type IIA topoisomerases. Nature, 450, 2007
4HMD	Crystal structure of cold-adapted chitinase from Moritella marina with a reaction intermediate - oxazolinium ion (NGO) 分子名称: 2-METHYL-4,5-DIHYDRO-(1,2-DIDEOXY-ALPHA-D-GLUCOPYRANOSO)[2,1-D]-1,3-OXAZOLE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Chitinase 60, ... 著者 Malecki, P.H, Vorgias, C.E, Raczynska, J.E, Rypniewski, W. 登録日 2012-10-18 公開日 2013-05-01 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 Structure of a complete four-domain chitinase from Moritella marina, a marine psychrophilic bacterium Acta Crystallogr.,Sect.D, 69, 2013
4HNM	Crystal structure of human catenin-beta-like 1 56 kDa fragment 分子名称: Beta-catenin-like protein 1 著者 Du, Z, Huang, X, Wang, G, Wu, Y. 登録日 2012-10-19 公開日 2013-07-31 最終更新日 2013-08-21 実験手法 X-RAY DIFFRACTION (2.9001 Å) 主引用文献 The structure of full-length human CTNNBL1 reveals a distinct member of the armadillo-repeat protein family. Acta Crystallogr.,Sect.D, 69, 2013
4HIL	1.25A Resolution Structure of Rat Type B Cytochrome b5 分子名称: Cytochrome b5 type B, PROTOPORPHYRIN IX CONTAINING FE, SODIUM ION 著者 Lovell, S, Battaile, K.P, Parthasarathy, S, Sun, N, Terzyan, S, Zhang, X, Rivera, M, Kuczera, K, Benson, D.R. 登録日 2012-10-11 公開日 2013-10-16 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 1.25A Resolution Structure of Rat Type B Cytochrome b5 To be Published
4HIX	Crystal structure of a humanised 3D6 Fab bound to amyloid beta peptide 分子名称: Beta-amyloid protein 40, Humanized 3D6 Fab heavy chain, Humanized 3D6 Fab light chain 著者 Miles, L.A, Crespi, G.A.N, Parker, M.W. 登録日 2012-10-12 公開日 2013-03-13 最終更新日 2014-03-19 実験手法 X-RAY DIFFRACTION (2.204 Å) 主引用文献 Bapineuzumab captures the N-terminus of the Alzheimer's disease amyloid-beta peptide in a helical conformation. Sci Rep, 3, 2013
2RIE	Crystal structure of the trimeric neck and carbohydrate recognition domain of human surfactant protein D in complex with 2-deoxy-L-glycero-D-manno-heptose 分子名称: 2-deoxy-beta-L-galacto-heptopyranose, CALCIUM ION, Pulmonary surfactant-associated protein D 著者 Wang, H, Head, J, Kosma, P, Sheikh, S, McDonald, B, Smith, K, Cafarella, T, Seaton, B, Crouch, E. 登録日 2007-10-10 公開日 2008-01-15 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Recognition of heptoses and the inner core of bacterial lipopolysaccharides by surfactant protein d. Biochemistry, 47, 2008
4HJC	Crystal structure of glycoprotein C from Rift Valley Fever Virus (non-glycosylated) 分子名称: ENVELOPE GLYCOPROTEIN 著者 Dessau, M, Modis, Y. 登録日 2012-10-12 公開日 2013-01-16 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (4.15 Å) 主引用文献 Crystal structure of glycoprotein C from Rift Valley fever virus. Proc.Natl.Acad.Sci.USA, 110, 2013
3F6Z	Crystal structure of Pseudomonas aeruginosa MliC in complex with hen egg white lysozyme 分子名称: Lysozyme C, Putative uncharacterized protein 著者 Ha, N.C, Yum, S. 登録日 2008-11-07 公開日 2008-12-23 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural basis for the recognition of lysozyme by MliC, a periplasmic lysozyme inhibitor in Gram-negative bacteria. Biochem.Biophys.Res.Commun., 378, 2009
2RJ6	B-specific alpha-1,3-galactosyltransferase G176R S235G mutant (AABB) + H-antigen disaccharide 分子名称: Glycoprotein-fucosylgalactoside alpha-galactosyltransferase, octyl 2-O-(6-deoxy-alpha-L-galactopyranosyl)-beta-D-galactopyranoside 著者 Evans, S.V, Alfaro, J.A. 登録日 2007-10-14 公開日 2008-02-05 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.41 Å) 主引用文献 ABO(H) blood group A and B glycosyltransferases recognize substrate via specific conformational changes. J.Biol.Chem., 283, 2008
2RJ5	B-specific alpha-1,3-galactosyltransferase G176R S235G mutant (AABB) +UDP 分子名称: GLYCEROL, Glycoprotein-fucosylgalactoside alpha-galactosyltransferase, MANGANESE (II) ION, ... 著者 Evans, S.V, Alfaro, J.A. 登録日 2007-10-14 公開日 2008-02-05 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 ABO(H) blood group A and B glycosyltransferases recognize substrate via specific conformational changes. J.Biol.Chem., 283, 2008
4HKB	CH67 Fab (unbound) from the CH65-67 Lineage 分子名称: CH67 heavy chain, CH67 light chain 著者 Schmidt, A.G, Harrison, S.C. 登録日 2012-10-15 公開日 2012-11-21 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody. Proc.Natl.Acad.Sci.USA, 110, 2013
2RKJ	Cocrystal structure of a tyrosyl-tRNA synthetase splicing factor with a group I intron RNA 分子名称: RNA (238-MER), RNA (5'-R(P*GP*CP*UP*U)-3'), Tyrosyl-tRNA synthetase 著者 Paukstelis, P.J, Chen, J.-H, Chase, E, Lambowitz, A.M, Golden, B.L. 登録日 2007-10-16 公開日 2008-01-08 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (4.5 Å) 主引用文献 Structure of a tyrosyl-tRNA synthetase splicing factor bound to a group I intron RNA. Nature, 451, 2008
4HKL	Crystal Structures of Mutant Endo-beta-1,4-xylanase II Complexed with substrate (1.15 A) and Products (1.6 A) 分子名称: Endo-1,4-beta-xylanase 2, IODIDE ION 著者 Langan, P, Wan, Q, Coates, L, Kovalevsky, A. 登録日 2012-10-15 公開日 2014-01-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 X-ray crystallographic studies of family 11 xylanase Michaelis and product complexes: implications for the catalytic mechanism. Acta Crystallogr.,Sect.D, 70, 2014
4HP3	Crystal structure of Tet3 in complex with a CpG dsDNA 分子名称: DNA (5'-D(*GP*CP*CP*AP*AP*CP*GP*TP*TP*GP*GP*C)-3'), LOC100036628 protein, UNKNOWN ATOM OR ION, ... 著者 Chao, X, Tempel, W, Bian, C, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) 登録日 2012-10-23 公開日 2012-12-05 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Tet3 CXXC Domain and Dioxygenase Activity Cooperatively Regulate Key Genes for Xenopus Eye and Neural Development. Cell(Cambridge,Mass.), 151, 2012
4HTI	Crystallographic structure of the membrane-proximal ectodomain of the human receptor-type protein-tyrosine phosphatase phogrin 分子名称: Receptor-type tyrosine-protein phosphatase N2 著者 Noguera, M.E, Jakoncic, J, Poskus, E, Ermacora, M.R. 登録日 2012-11-01 公開日 2012-11-28 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.954 Å) 主引用文献 X-ray structure of the mature ectodomain of phogrin. J.Struct.Funct.Genom., 16, 2015
4HTQ	Mitigation of X-ray damage in macromolecular crystallography by submicrometer line focusing; total dose 6.70 x 10e+11 X-ray photons 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Lysozyme C, ... 著者 Duke, N.E.C, Finfrock, Y.Z, Stern, E.Z, Alkire, R.W, Lazarski, K, Joachimiak, A. 登録日 2012-11-01 公開日 2013-05-15 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (1.399 Å) 主引用文献 Mitigation of X-ray damage in macromolecular crystallography by submicrometre line focusing. Acta Crystallogr.,Sect.D, 69, 2013

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