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2RJ6

B-specific alpha-1,3-galactosyltransferase G176R S235G mutant (AABB) + H-antigen disaccharide

Summary for 2RJ6
Entry DOI10.2210/pdb2rj6/pdb
Related2RIT 2RIX 2RIY 2RIZ 2RJ0 2RJ1 2RJ4 2RJ5 2RJ7 2RJ8 2RJ9
DescriptorGlycoprotein-fucosylgalactoside alpha-galactosyltransferase, octyl 2-O-(6-deoxy-alpha-L-galactopyranosyl)-beta-D-galactopyranoside (3 entities in total)
Functional Keywordsaabb+ha, blood group antigen, glycoprotein, glycosyltransferase, golgi apparatus, manganese, membrane, metal-binding, secreted, signal-anchor, transferase, transmembrane
Biological sourceHomo sapiens (human)
Cellular locationGolgi apparatus, Golgi stack membrane; Single-pass type II membrane protein: P16442
Total number of polymer chains1
Total formula weight34794.18
Authors
Evans, S.V.,Alfaro, J.A. (deposition date: 2007-10-14, release date: 2008-02-05, Last modification date: 2024-02-21)
Primary citationAlfaro, J.A.,Zheng, R.B.,Persson, M.,Letts, J.A.,Polakowski, R.,Bai, Y.,Borisova, S.N.,Seto, N.O.,Lowary, T.L.,Palcic, M.M.,Evans, S.V.
ABO(H) blood group A and B glycosyltransferases recognize substrate via specific conformational changes.
J.Biol.Chem., 283:10097-10108, 2008
Cited by
PubMed: 18192272
DOI: 10.1074/jbc.M708669200
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.41 Å)
Structure validation

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