4HTI

Crystallographic structure of the membrane-proximal ectodomain of the human receptor-type protein-tyrosine phosphatase phogrin

Summary for 4HTI

Entry DOI	10.2210/pdb4hti/pdb
Descriptor	Receptor-type tyrosine-protein phosphatase N2 (2 entities in total)
Functional Keywords	phogrin, ia-2beta, protein-tyrosine phosphatase, transmembrane protein, diabetes, autoimmunity, glycoprotein, receptor, hydrolase, ferredoxin-like fold
Biological source	Homo sapiens (human)
Cellular location	Cytoplasmic vesicle, secretory vesicle membrane ; Single-pass type I membrane protein . IA-2beta60: Cytoplasmic vesicle, secretory vesicle membrane : Q92932
Total number of polymer chains	1
Total formula weight	10826.07
Authors	Noguera, M.E.,Jakoncic, J.,Poskus, E.,Ermacora, M.R. (deposition date: 2012-11-01, release date: 2012-11-28, Last modification date: 2023-09-20)
Primary citation	Noguera, M.E.,Primo, M.E.,Jakoncic, J.,Poskus, E.,Solimena, M.,Ermacora, M.R. X-ray structure of the mature ectodomain of phogrin. J.Struct.Funct.Genom., 16:1-9, 2015 Cited by PubMed: 25421040 DOI: 10.1007/s10969-014-9191-0 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.954 Å)

Structure validation