PDB: 45459 件ウェブページステータス検索Chemie searchBIRD

---

7YXJ	Drosophila melanogaster JMJD7 (dmJMJD7) in complex with Mn and 2,4-PDCA 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GH14974p, ... 著者 Chowdhury, R, Schofield, C.J. 登録日 2022-02-16 公開日 2022-04-27 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Conservation of the unusual dimeric JmjC fold of JMJD7 from Drosophila melanogaster to humans. Sci Rep, 12, 2022
7YXG	Drosophila melanogaster JMJD7 (dmJMJD7) in complex with Mn and 2OG 分子名称: 1,2-ETHANEDIOL, 2-OXOGLUTARIC ACID, GH14974p, ... 著者 Chowdhury, R, Schofield, C.J. 登録日 2022-02-16 公開日 2022-04-27 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.641 Å) 主引用文献 Conservation of the unusual dimeric JmjC fold of JMJD7 from Drosophila melanogaster to humans. Sci Rep, 12, 2022
7YXK	Drosophila melanogaster JMJD7 (dmJMJD7) in complex with Mn and N-oxalyl-D-alanine (NODA) 分子名称: (2~{R})-2-(carboxycarbonylamino)propanoic acid, 1,2-ETHANEDIOL, ACETATE ION, ... 著者 Chowdhury, R, Schofield, C.J. 登録日 2022-02-16 公開日 2022-04-27 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.43 Å) 主引用文献 Conservation of the unusual dimeric JmjC fold of JMJD7 from Drosophila melanogaster to humans. Sci Rep, 12, 2022
7ZEJ	Crystal structure of the human MGC45594 gene product in complex with celecoxib. 分子名称: 4-[5-(4-METHYLPHENYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL]BENZENESULFONAMIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Prostaglandin reductase 3 著者 Shafqat, N, Yue, W.W, Koekemoer, L, Niesen, F, Ugochukwu, E, Vollmar, M, Weigelt, J, Krojer, T, Pike, A, Chaikaud, A, Von Delft, F, Arrowsmith, C, Bountra, C, Edwards, A, Opperman, U, Structural Genomics Consortium (SGC) 登録日 2022-03-31 公開日 2022-05-04 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Human prostaglandin/alkenal reductases: substrate specificities, inhibitor profiles, structural insights and subcellular localization suggest protective roles in inflammatory and oxidative stress conditions. To Be Published
7Z60	Human transthyretin (TTR) complexed with Quercetin 3-O-beta-D-galactoside 分子名称: 1,2-ETHANEDIOL, 2-[3,4-bis(oxidanyl)phenyl]-3-[(2S,3R,4S,5R,6R)-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-5,7-bis(oxidanyl)chromen-4-one, IMIDAZOLE, ... 著者 Ciccone, L, Braca, A, Orlandini, E, Nencetti, S. 登録日 2022-03-10 公開日 2022-05-18 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Antioxidant Quercetin 3-O-Glycosylated Plant Flavonols Contribute to Transthyretin Stabilization Crystals, 12, 2022
7YZ9	Structure of catalytic domain of Rv1625c bound to nanobody NB4 分子名称: 3'-O-(N-METHYLANTHRANILOYL)-GUANOSINE-5'-TRIPHOSPHATE, Adenylate cyclase, GLYCEROL, ... 著者 Khanppnavar, B, Mehta, V.J, Iype, T, Korkhov, V.M. 登録日 2022-02-19 公開日 2022-08-31 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Structure of Mycobacterium tuberculosis Cya, an evolutionary ancestor of the mammalian membrane adenylyl cyclases. Elife, 11, 2022
4ID1	HIV-1 Integrase Catalytic Core Domain Complexed with Allosteric Inhibitor 分子名称: (2S)-tert-butoxy[4-(3,4-dihydro-2H-chromen-6-yl)-2-methylquinolin-3-yl]ethanoic acid, Gag-Pol polyprotein, SULFATE ION 著者 Feng, L, Kvaratskhelia, M. 登録日 2012-12-11 公開日 2013-05-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Allosteric integrase inhibitor potency is determined through the inhibition of HIV-1 particle maturation. Proc.Natl.Acad.Sci.USA, 110, 2013
4IH6	Hepatitis C Virus polymerase NS5B (BK) with fragment-based compounds 分子名称: (5S)-3-(4-tert-butylbenzyl)-5-(propan-2-yl)imidazolidine-2,4-dione, RNA-directed RNA polymerase 著者 Harris, S.F, Wong, A. 登録日 2012-12-18 公開日 2013-07-03 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 De novo fragment design: a medicinal chemistry approach to fragment-based lead generation. J.Med.Chem., 56, 2013
4IH7	Hepatitis C Virus polymerase NS5B (BK) with fragment-based compounds 分子名称: 3-(3-tert-butylphenyl)pyridin-2(1H)-one, RNA-directed RNA polymerase, ZINC ION 著者 Harris, S.F, Wong, A. 登録日 2012-12-18 公開日 2013-07-03 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 De novo fragment design: a medicinal chemistry approach to fragment-based lead generation. J.Med.Chem., 56, 2013
4IHL	Human 14-3-3 isoform zeta in complex with a diphoyphorylated C-RAF peptide and Cotylenin A 分子名称: (1R,3aS,4R,5R,6R,9aR,10E)-6-({(1S,2R,4S,5R,6R,8S,9S)-5-hydroxy-2-(methoxymethyl)-9-methyl-9-[(2S)-oxiran-2-yl]-3,7,10,1 1-tetraoxatricyclo[6.2.1.0~1,6~]undec-4-yl}oxy)-1-(methoxymethyl)-4,9a-dimethyl-7-(propan-2-yl)-1,2,3,3a,4,5,6,8,9,9a-de cahydrodicyclopenta[a,d][8]annulene-1,5-diol, 14-3-3 protein zeta/delta, POTASSIUM ION, ... 著者 Molzan, M, Ottmann, C. 登録日 2012-12-19 公開日 2013-09-25 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Stabilization of Physical RAF/14-3-3 Interaction by Cotylenin A as Treatment Strategy for RAS Mutant Cancers. Acs Chem.Biol., 8, 2013
4IF8	Structure Of Vaspin 分子名称: SULFATE ION, Serpin A12 著者 Kuettner, E.B, Strater, N, Heiker, J.T, Kloting, N, Kovacs, P, Schultz, S, Kern, M, Stumvoll, M, Bluher, M, Beck-Sickinger, A.G. 登録日 2012-12-14 公開日 2013-02-13 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 Vaspin inhibits kallikrein 7 by serpin mechanism Cell.Mol.Life Sci., 70, 2013
4IQS	RNA 8mer duplex modified with 4-Se-Uridine 分子名称: RNA (5'-R(*GP*UP*GP*(S5)P*AP*CP*AP*C)-3') 著者 Sheng, J, Gan, J, Soares, A, Huang, Z. 登録日 2013-01-13 公開日 2013-12-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural insights of non-canonical U*U pair and Hoogsteen interaction probed with Se atom. Nucleic Acids Res., 41, 2013
4IQ4	Structure of a 16 nm protein cage designed by fusing symmetric oligomeric domains, triple mutant, P21212 form 分子名称: Non-haem bromoperoxidase BPO-A2, Matrix protein 1 著者 Lai, Y.-T, Sawaya, M.R, Yeates, T.O. 登録日 2013-01-10 公開日 2013-07-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.495 Å) 主引用文献 Structure and flexibility of nanoscale protein cages designed by symmetric self-assembly. J.Am.Chem.Soc., 135, 2013
4IRA	CobR in complex with FAD 分子名称: 4-hydroxyphenylacetate 3-monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION 著者 Lawrence, A.D, Scott, A.F, Warren, M.J, Pickersgill, R.W. 登録日 2013-01-14 公開日 2014-01-29 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Biophysical characterisation and structure-function analysis of Brucella melitensis CobR: Protein-flavin interactions determine function and stability To be Published
4IZQ	GGGCATGCCC in the A-DNA Form 分子名称: DNA (5'-D(*GP*GP*GP*CP*AP*TP*GP*CP*CP*C)-3') 著者 Hall, J.P, Ruiz-Morte, S, Murray, C.A, Cardin, C.J. 登録日 2013-01-30 公開日 2014-02-05 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 GGGCATGCCC in the A-DNA Form To be Published
4ISR	Binding domain of Botulinum neurotoxin DC in complex with rat synaptotagmin II 分子名称: Neurotoxin, SULFATE ION, Synaptotagmin-2 著者 Berntsson, R.P.-A, Peng, L, Svensson, L.M, Dong, M, Stenmark, P. 登録日 2013-01-17 公開日 2013-08-14 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.59 Å) 主引用文献 Crystal Structures of Botulinum Neurotoxin DC in Complex with Its Protein Receptors Synaptotagmin I and II. Structure, 21, 2013
4ITV	Structure of a 16 nm protein cage designed by fusing symmetric oligomeric domains, triple mutant, P212121 form 分子名称: Non-haem bromoperoxidase BPO-A2, Matrix protein 1 著者 Lai, Y.-T, Sawaya, M.R, Yeates, T.O. 登録日 2013-01-18 公開日 2013-07-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.598 Å) 主引用文献 Structure and flexibility of nanoscale protein cages designed by symmetric self-assembly. J.Am.Chem.Soc., 135, 2013
4ISC	Crystal structure of a putative Methyltransferase from Pseudomonas syringae 分子名称: BETA-MERCAPTOETHANOL, Methyltransferase 著者 Filippova, E.V, Wawrzak, Z, Minasov, G, Shuvalova, L, Kiryukhina, O, Clancy, S, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) 登録日 2013-01-16 公開日 2013-02-20 最終更新日 2018-01-24 実験手法 X-RAY DIFFRACTION (2.78 Å) 主引用文献 Crystal structure of a putative Methyltransferase from Pseudomonas syringae To be Published
4J3H	Ring cycle for dilating and constricting the nuclear pore: structure of a Nup54 homo-tetramer. 分子名称: CALCIUM ION, Nuclear pore complex protein Nup54 著者 Solmaz, S.R, Blobel, G, Melcak, I. 登録日 2013-02-05 公開日 2013-04-10 最終更新日 2013-04-17 実験手法 X-RAY DIFFRACTION (1.5002 Å) 主引用文献 Ring cycle for dilating and constricting the nuclear pore. Proc.Natl.Acad.Sci.USA, 110, 2013
4ISQ	Binding domain of Botulinum neurotoxin DC in complex with human synaptotagmin I 分子名称: GLYCEROL, Neurotoxin, SULFATE ION, ... 著者 Berntsson, R.P.-A, Peng, L, Svensson, L.M, Dong, M, Stenmark, P. 登録日 2013-01-17 公開日 2013-08-14 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Crystal Structures of Botulinum Neurotoxin DC in Complex with Its Protein Receptors Synaptotagmin I and II. Structure, 21, 2013
4IV8	Crystal structure of N-methyl transferase from Plasmodium knowlesi complexed with S-adenosyl methionine 分子名称: BETA-MERCAPTOETHANOL, Phosphoethanolamine N-methyltransferase,putative, S-ADENOSYLMETHIONINE 著者 Lukk, T, Nair, S.K. 登録日 2013-01-22 公開日 2014-02-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Phosphoethanolamine N-methyl transferase is a Malarial drug target. To be Published
4IVJ	Structure of a 16 nm protein cage designed by fusing symmetric oligomeric domains, triple mutant, I222 form 分子名称: Non-haem bromoperoxidase BPO-A2, Matrix protein 1 著者 Lai, Y.-T, Sawaya, M.R, Yeates, T.O. 登録日 2013-01-23 公開日 2013-07-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (7.351 Å) 主引用文献 Structure and flexibility of nanoscale protein cages designed by symmetric self-assembly. J.Am.Chem.Soc., 135, 2013
4J0S	Crystal Structure of the first bromodomain of human BRD4 in complex with a 3,5-dimethylisoxazol ligand 分子名称: 1,2-ETHANEDIOL, 3-(3,5-dimethyl-1,2-oxazol-4-yl)-5-[(S)-hydroxy(phenyl)methyl]phenol, Bromodomain-containing protein 4 著者 Filippakopoulos, P, Picaud, S, Qi, J, Felletar, I, Hewings, D.S, von Delft, F, Conway, S.J, Bountra, C, Arrowsmith, C.H, Edwards, A, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2013-01-31 公開日 2013-02-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Optimization of 3,5-dimethylisoxazole derivatives as potent bromodomain ligands. J.Med.Chem., 56, 2013
4IYP	structure of the nPP2Ac-alpha4 complex 分子名称: Immunoglobulin-binding protein 1, Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform 著者 Jiang, L, Stanevich, V, Satyshur, K.A, Xing, Y. 登録日 2013-01-29 公開日 2013-04-17 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (2.797 Å) 主引用文献 Structural basis of protein phosphatase 2A stable latency. Nat Commun, 4, 2013
4IZH	Crystal Structure of the Alpha1 dimer of Thermus thermophilus Transhydrogenase in P6 分子名称: GLYCEROL, NAD/NADP transhydrogenase alpha subunit 1 著者 Stout, C.D, Yamaguchi, M, Leung, J. 登録日 2013-01-29 公開日 2014-01-29 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure analysis of Thermus thermophilus transhydrogenase soluble domains To be Published

<1632163316341635163616371638163916401641164216431644164516461647>