4ISR

Binding domain of Botulinum neurotoxin DC in complex with rat synaptotagmin II

Summary for 4ISR

• Entry DOI: 10.2210/pdb4isr/pdb
• Related: 4ISQ
• Descriptor: Neurotoxin, Synaptotagmin-2, SULFATE ION, ... (4 entities in total)
• Functional Keywords: membrane binding, synaptotagmin and ganglioside binding, toxin
• Biological source: Clostridium botulinum; More
• Cellular location: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass membrane protein: P29101
• Total number of polymer chains: 6
• Total formula weight: 158917.37

Authors

Berntsson, R.P.-A.,Peng, L.,Svensson, L.M.,Dong, M.,Stenmark, P. (deposition date: 2013-01-17, release date: 2013-08-14, Last modification date: 2024-02-28)

• Primary citation: Berntsson, R.P.,Peng, L.,Svensson, L.M.,Dong, M.,Stenmark, P.; Crystal Structures of Botulinum Neurotoxin DC in Complex with Its Protein Receptors Synaptotagmin I and II.; Structure, 21:1602-1611, 2013; PubMed: 23932591; DOI: 10.1016/j.str.2013.06.026

Experimental method

X-RAY DIFFRACTION (2.59 Å)