PDB: 45459 件ウェブページステータス検索Chemie searchBIRD

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4WX7	Crystal structure of adenovirus 8 protease with a nitrile inhibitor 分子名称: 3-[2-(3,5-dichlorophenyl)-2-methylpropanoyl]-N-(2-{[(2Z)-2-iminoethyl]amino}-2-oxoethyl)-4-methoxybenzamide, PVI, Protease 著者 Grosche, P, Sirockin, F, Mac Sweeney, A, Ramage, P, Erbel, P, Melkko, S, Bernardi, A, Hughes, N, Ellis, D, Combrink, K, Jarousse, N, Altmann, E. 登録日 2014-11-13 公開日 2015-01-14 最終更新日 2015-01-28 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure-based design and optimization of potent inhibitors of the adenoviral protease. Bioorg.Med.Chem.Lett., 25, 2015
6U1I	Thermus thermophilus D-alanine-D-alanine ligase in complex with ADP, phosphorylated D-cycloserine, Mg2+ and K+ 分子名称: ADENOSINE-5'-DIPHOSPHATE, D-alanine--D-alanine ligase, MAGNESIUM ION, ... 著者 Pederick, J.L, Bruning, J.B, Thompson, A.P. 登録日 2019-08-15 公開日 2020-05-06 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 d-Alanine-d-alanine ligase as a model for the activation of ATP-grasp enzymes by monovalent cations. J.Biol.Chem., 295, 2020
5G4X	The crystal structure of the SHANK3 N-terminus 分子名称: 1,2-ETHANEDIOL, SH3 AND MULTIPLE ANKYRIN REPEAT DOMAINS PROTEIN 3 著者 Zacharchenko, T, Barsukov, I. 登録日 2016-05-17 公開日 2017-01-25 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.166 Å) 主引用文献 SHANK proteins limit integrin activation by directly interacting with Rap1 and R-Ras. Nat. Cell Biol., 19, 2017
5G2Q	The crystal structure of a S-selective transaminase from Arthrobacter sp. with alanine bound 分子名称: 2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-PROPIONIC ACID, TRANSAMINASE 著者 van Oosterwijk, N, Willies, S, Hekelaar, J, Terwisscha van Scheltinga, A.C, Turner, N.J, Dijkstra, B.W. 登録日 2016-04-12 公開日 2016-07-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural Basis of Substrate Range and Enantioselectivity of Two S-Selective Omega- Transaminases Biochemistry, 55, 2016
4WXZ	PdxS (G. stearothermophilus) co-crystallized with R5P 分子名称: Pyridoxal biosynthesis lyase PdxS 著者 Smith, J.L, Smith, A.M. 登録日 2014-11-14 公開日 2015-01-14 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structures capture three states in the catalytic cycle of a pyridoxal phosphate (PLP) synthase. J.Biol.Chem., 290, 2015
6U7V	xRRM structure of spPof8 分子名称: NITRATE ION, Protein pof8 著者 Kim, J.-K, Hu, X, Yu, C, Jun, H.-I, Liu, J, Sankaran, B, Huang, L, Qiao, F. 登録日 2019-09-03 公開日 2020-09-09 最終更新日 2021-03-24 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 Quality-Control Mechanism for Telomerase RNA Folding in the Cell. Cell Rep, 33, 2020
5G39	PsbO subunit of Photosystem II, beta barrel domain at 297K, pH 6 分子名称: CALCIUM ION, PHOTOSYSTEM II MANGANESE-STABILIZING POLYPEPTIDE 著者 Bommer, M, Bondar, A.N, Zouni, A, Dobbek, H, Dau, H. 登録日 2016-04-24 公開日 2016-08-10 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystallographic and Computational Analysis of the Barrel Part of the Psbo Protein of Photosystem II -Carboxylate-Water Clusters as Putative Proton Transfer Relays and Structural Switches Biochemistry, 55, 2016
4X7L	Co-crystal Structure of PERK bound to 4-{2-amino-4-methyl-3-[2-(methylamino)-1,3-benzothiazol-6-yl]benzoyl}-1-methyl-2,5-diphenyl-1,2-dihydro-3H-pyrazol-3-one inhibitor 分子名称: 4-{2-amino-4-methyl-3-[2-(methylamino)-1,3-benzothiazol-6-yl]benzoyl}-1-methyl-2,5-diphenyl-1,2-dihydro-3H-pyrazol-3-one, Eukaryotic translation initiation factor 2-alpha kinase 3,Eukaryotic translation initiation factor 2-alpha kinase 3, GLYCEROL, ... 著者 Shaffer, P.L, Long, A.M, Chen, H. 登録日 2014-12-09 公開日 2015-01-28 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Discovery of 1H-Pyrazol-3(2H)-ones as Potent and Selective Inhibitors of Protein Kinase R-like Endoplasmic Reticulum Kinase (PERK). J.Med.Chem., 58, 2015
5G3A	PsbO subunit of Photosystem II, beta barrel domain at 100K, pH 10 分子名称: CALCIUM ION, PHOTOSYSTEM II MANGANESE-STABILIZING POLYPEPTIDE 著者 Bommer, M, Bondar, A.N, Zouni, A, Dobbek, H, Dau, H. 登録日 2016-04-25 公開日 2016-08-10 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.224 Å) 主引用文献 Crystallographic and Computational Analysis of the Barrel Part of the Psbo Protein of Photosystem II -Carboxylate-Water Clusters as Putative Proton Transfer Relays and Structural Switches Biochemistry, 55, 2016
4X2H	Sac3N peptide bound to Mex67:Mtr2 分子名称: Putative mRNA export protein, Putative uncharacterized protein, SER-SER-VAL-PHE-GLY-ALA-PRO-ALA 著者 Aibara, S, Valkov, E, Stewart, M. 登録日 2014-11-26 公開日 2015-06-17 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural Characterization of the Chaetomium thermophilum TREX-2 Complex and its Interaction with the mRNA Nuclear Export Factor Mex67:Mtr2. Structure, 23, 2015
4X96	Low resolution crystal structure of Lecithin:Cholesterol Acyltransferase (LCAT; residues 21-397) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Phosphatidylcholine-sterol acyltransferase, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose 著者 Glukhova, A, Tesmer, J.J.G. 登録日 2014-12-11 公開日 2015-03-25 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (8.69 Å) 主引用文献 Structure and function of lysosomal phospholipase A2 and lecithin:cholesterol acyltransferase. Nat Commun, 6, 2015
6K5I	Crystal structure of the E148D/R147A/F317A mutant CLC-ec1 in the presence of 20 mM NaBr 分子名称: BROMIDE ION, Fab fragment, heavy chain, ... 著者 Park, K, Lim, H.H. 登録日 2019-05-29 公開日 2019-08-28 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.022 Å) 主引用文献 Mutation of external glutamate residue reveals a new intermediate transport state and anion binding site in a CLC Cl-/H+antiporter. Proc.Natl.Acad.Sci.USA, 116, 2019
5G20	Leishmania major N-myristoyltransferase in complex with a quinoline inhibitor (compound 19). 分子名称: 6-(BENZYLOXY)-4-(ETHYLSULFANYL)-3-[(MORPHOLIN-4-YL), DIMETHYL SULFOXIDE, GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE, ... 著者 Goncalves, V, Brannigan, J.A, Laporte, A, Bell, A.S, Roberts, S.M, Wilkinson, A.J, Leatherbarrow, R.J, Tate, E.W. 登録日 2016-04-06 公開日 2017-02-15 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.52 Å) 主引用文献 Structure-guided optimization of quinoline inhibitors of Plasmodium N-myristoyltransferase. Medchemcomm, 8, 2017
7CWK	Structure of a triple-helix region of human collagen type I 分子名称: Collagen type I 著者 Zhu, Y, Yang, X, Sun, F. 登録日 2020-08-29 公開日 2021-09-01 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.539 Å) 主引用文献 Conformation in a triple-helix region of human collagen type I To Be Published
6UDG	Crystal structure of a Probable thiol peroxidase from Elizabethkingia anophelis NUHP1 分子名称: Thiol peroxidase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2019-09-19 公開日 2019-10-16 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Crystal structure of a Probable thiol peroxidase from Elizabethkingia anophelis NUHP1 TO BE PUBLISHED
4X4W	Crystal structure of the full-length human mitochondrial CCA-adding enzyme 分子名称: CCA tRNA nucleotidyltransferase 1, mitochondrial, CHLORIDE ION, ... 著者 Kuhn, C.-D, Joshua-Tor, L. 登録日 2014-12-03 公開日 2015-02-11 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 On-Enzyme Refolding Permits Small RNA and tRNA Surveillance by the CCA-Adding Enzyme. Cell, 160, 2015
4X5W	HLA-DR1 with CLIP102-120(M107W) 分子名称: HLA class II histocompatibility antigen gamma chain, HLA class II histocompatibility antigen, DR alpha chain, ... 著者 Guenther, S, Freund, C. 登録日 2014-12-06 公開日 2016-03-09 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.34 Å) 主引用文献 MHC class II complexes sample intermediate states along the peptide exchange pathway. Nat Commun, 7, 2016
5HAX	Crystal structure of Chaetomium thermophilum Nup170 NTD-Nup53 complex 分子名称: 1,2-ETHANEDIOL, GLYCEROL, Nucleoporin NUP170, ... 著者 Lin, D.H, Mobbs, G, Hoelz, A. 登録日 2015-12-31 公開日 2016-04-20 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Architecture of the symmetric core of the nuclear pore. Science, 352, 2016
5A5F	CRYSTAL STRUCTURE OF MURD LIGASE FROM ESCHERICHIA COLI IN COMPLEX WITH UMA AND ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, MALONATE ION, UDP-N-ACETYLMURAMOYLALANINE--D-GLUTAMATE LIGASE, ... 著者 Sink, R, Kotnik, M, Zega, A, Barreteau, H, Gobec, S, Blanot, D, Dessen, A, Contreras-Martel, C. 登録日 2015-06-17 公開日 2016-04-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystallographic Study of Peptidoglycan Biosynthesis Enzyme MurD: Domain Movement Revisited. PLoS ONE, 11, 2016
5IN2	Crystal structure of extra cellular Cu/Zn Superoxide Dismutase from Onchocerca volvulus at 1.5 Angstrom; Insight into novel binding site and new inhibitors 分子名称: AZIDE ION, CHLORIDE ION, COPPER (II) ION, ... 著者 Moustafa, A, Betzel, C, Perbandt, M. 登録日 2016-03-07 公開日 2017-03-29 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Crystal structure of extracellular Cu/Zn Superoxide Dismutase from Onchocerca volvulus at 1.5 Angstrom; Insight into novel binding site and new inhibitors To Be Published
5I1G	CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV3-53/IGKV3-11 分子名称: FAB HEAVY CHAIN, FAB LIGHT CHAIN, SULFATE ION 著者 Teplyakov, A, Obmolova, G, Malia, T, Luo, J, Gilliland, G. 登録日 2016-02-05 公開日 2016-06-08 最終更新日 2016-08-03 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural diversity in a human antibody germline library. Mabs, 8, 2016
5I2K	Structure of the human GluN1/GluN2A LBD in complex with 7-{[ethyl(4-fluorophenyl)amino]methyl}-N,2-dimethyl-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-3-carboxamide (compound 19) 分子名称: 7-{[ethyl(4-fluorophenyl)amino]methyl}-N,2-dimethyl-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-3-carboxamide, GLUTAMIC ACID, GLYCINE, ... 著者 Wallweber, H.J.A, Lupardus, P.J. 登録日 2016-02-09 公開日 2016-03-16 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.86 Å) 主引用文献 Discovery of GluN2A-Selective NMDA Receptor Positive Allosteric Modulators (PAMs): Tuning Deactivation Kinetics via Structure-Based Design. J.Med.Chem., 59, 2016
5I0K	Insights into Substrate Modification by Dehydratases from Type I Polyketide Synthases 分子名称: CROTONYL COENZYME A, Phthiocerol synthesis polyketide synthase type I PpsC 著者 Faille, A, Mourey, L, Pedelacq, J.D. 登録日 2016-02-04 公開日 2017-08-09 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.197 Å) 主引用文献 Insights into Substrate Modification by Dehydratases from Type I Polyketide Synthases. J. Mol. Biol., 429, 2017
5AIE	Not4 ring domain in complex with Ubc4 分子名称: GENERAL NEGATIVE REGULATOR OF TRANSCRIPTION SUBUNIT 4, UBIQUITIN-CONJUGATING ENZYME E2 4, ZINC ION 著者 Bhaskar, V, Basquin, J, Conti, E. 登録日 2015-02-12 公開日 2015-04-29 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Architecture of the Ubiquitylation Module of the Yeast Ccr4-not Complex. Structure, 23, 2015
5A64	Crystal structure of mouse thiamine triphosphatase in complex with thiamine triphosphate. 分子名称: 1,2-ETHANEDIOL, THIAMINE TRIPHOSPHATASE, TRIETHYLENE GLYCOL, ... 著者 Martinez, J, Truffault, V, Hothorn, M. 登録日 2015-06-24 公開日 2015-08-05 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural Determinants for Substrate Binding and Catalysis in Triphosphate Tunnel Metalloenzymes. J.Biol.Chem., 290, 2015

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