PDB: 19040 件ウェブページステータス検索Chemie searchBIRD

---

6EPO	RAS GUANINE EXCHANGE FACTOR SOS1 (REM-CDC25) IN COMPLEX WITH KRAS(G12C) AND FRAGMENT SCREENING HIT F3 分子名称: 3-(4-chlorophenyl)propan-1-amine, GLYCEROL, GTPase KRas, ... 著者 Hillig, R.C, Moosmayer, D, Hilpmann, A, Bader, B, Schroeder, J, Wortmann, L, Sautier, B, Kahmann, J, Wegener, D, Briem, H, Petersen, K, Badock, V. 登録日 2017-10-12 公開日 2019-02-06 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Discovery of potent SOS1 inhibitors that block RAS activation via disruption of the RAS-SOS1 interaction. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6EKM	Crystal structure of mammalian Rev7 in complex with human Rev3 second binding site 分子名称: DNA polymerase zeta catalytic subunit, Mitotic spindle assembly checkpoint protein MAD2B 著者 Huber, F, Tropia, L, Emamzadah, S, Halazonetis, T. 登録日 2017-09-26 公開日 2018-10-10 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.76 Å) 主引用文献 Crystal structure of mammalian Rev7 in complex with human Rev3 To Be Published
6ETD	The Structure of the Mo-insertase domain Cnx1E from Arabidopsis thaliana in complex with AMP 分子名称: 1,2-ETHANEDIOL, ACETYL GROUP, ADENOSINE MONOPHOSPHATE, ... 著者 Krausze, J. 登録日 2017-10-26 公開日 2018-07-18 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.723 Å) 主引用文献 The functional principle of eukaryotic molybdenum insertases. Biochem. J., 475, 2018
3DKB	Crystal Structure of A20, 2.5 angstrom 分子名称: Tumor necrosis factor, alpha-induced protein 3 著者 Lin, S.-C, Chung, J.Y, Lo, Y.-C, Wu, H. 登録日 2008-06-24 公開日 2008-07-08 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Molecular basis for the unique deubiquitinating activity of the NF-kappaB inhibitor A20 J.Mol.Biol., 376, 2008
6FAF	Crystal structure of human carbonic anhydrase I in complex with the 3-(2,5-dimethylphenyl)-1-(2-hydroxy-5-sulfamoylphenyl)urea inhibitor 分子名称: 1-(2,5-dimethylphenyl)-3-(2-oxidanyl-5-sulfamoyl-phenyl)urea, Carbonic anhydrase 1, GLYCEROL, ... 著者 Ferraroni, M, Supuran, C.T, Bozdag, M, Chiapponi, D. 登録日 2017-12-15 公開日 2018-10-10 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Discovery of 4-Hydroxy-3-(3-(phenylureido)benzenesulfonamides as SLC-0111 Analogues for the Treatment of Hypoxic Tumors Overexpressing Carbonic Anhydrase IX. J. Med. Chem., 61, 2018
6FEC	Human cap-dependent 48S pre-initiation complex 分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Schaffitzel, C, Schaffitzel, C. 登録日 2017-12-31 公開日 2018-03-14 最終更新日 2018-10-03 実験手法 ELECTRON MICROSCOPY (6.3 Å) 主引用文献 Structure of a human cap-dependent 48S translation pre-initiation complex. Nucleic Acids Res., 46, 2018
3DVM	Crystal Structure of Ca2+/CaM-CaV2.1 IQ domain complex 分子名称: CALCIUM ION, Calmodulin, Voltage-dependent P/Q-type calcium channel subunit alpha-1A 著者 Kim, E.Y, Rumpf, C.H, Fujiwara, Y, Cooley, E.S, Van Petegem, F, Minor, D.L. 登録日 2008-07-18 公開日 2008-11-04 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structures of Ca(V)2 Ca(2+)/CaM-IQ Domain Complexes Reveal Binding Modes that Underlie Calcium-Dependent Inactivation and Facilitation. Structure, 16, 2008
3DGF	Structure of a histidine kinase-response regulator complex reveals insights into Two-component signaling and a novel cis-autophosphorylation mechanism 分子名称: Response regulator 著者 Casino, P, Marina, A. 登録日 2008-06-13 公開日 2009-07-07 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural Insight into Partner Specificity and Phosphoryl Transfer in Two-Component Signal Transduction. Cell(Cambridge,Mass.), 139, 2009
3E9C	Structure of a tryptic core fragment of TIGAR from Danio rerio 分子名称: POTASSIUM ION, Zgc:56074 著者 Li, H, Jogl, G. 登録日 2008-08-21 公開日 2008-12-16 最終更新日 2017-10-25 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 TIGAR (TP53 induced glycolysis and apoptosis regulator) is a fructose-2,6- and fructose-1,6-bisphosphatase To be Published
3ENB	Crystal Structure of PRP8 core domain IV 分子名称: Pre-mRNA-processing-splicing factor 8 著者 Schellenberg, M.J, Ritchie, D.B, MacMillan, A.M. 登録日 2008-09-25 公開日 2008-10-07 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structural elucidation of a PRP8 core domain from the heart of the spliceosome. Nat.Struct.Mol.Biol., 15, 2008
6FNC	Mono- and bivalent 14-3-3 inhibitors for characterizing supramolecular lysine-PEG interactions in proteins 分子名称: 14-3-3 protein zeta/delta, BENZOIC ACID, CALCIUM ION, ... 著者 Bier, D, Ottann, C. 登録日 2018-02-02 公開日 2018-07-04 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 Mono- and Bivalent 14-3-3 Inhibitors for Characterizing Supramolecular "Lysine Wrapping" of Oligoethylene Glycol (OEG) Moieties in Proteins. Chemistry, 24, 2018
6FPS	Crystal structure of 4-oxalocrotonate tautomerase triple mutant L8Y/M45Y/F50A 分子名称: 2-hydroxymuconate tautomerase, GLYCEROL, PHOSPHATE ION 著者 Pijning, T, Thunnissen, A.M.W.H. 登録日 2018-02-12 公開日 2019-03-06 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Enantioselective Synthesis of Pharmaceutically Active gamma-Aminobutyric Acids Using a Tailor-Made Artificial Michaelase in One-Pot Cascade Reactions. ACS Catal, 9, 2019
3E57	Crystal structure of Tm1382, a putative Nudix hydrolase 分子名称: uncharacterized protein Tm1382 著者 Choi, W, Cooper, D.R, Derewenda, Z.S, Integrated Center for Structure and Function Innovation (ISFI) 登録日 2008-08-13 公開日 2008-09-30 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Crystal structure of Tm1382, a putative Nudix hydrolase To be Published
6FN9	Mono- and bivalent 14-3-3 inhibitors for characterizing supramolecular lysine-PEG interactions in proteins 分子名称: 14-3-3 protein zeta/delta, BENZOIC ACID, GLYCEROL, ... 著者 Bier, D, Ottmann, C. 登録日 2018-02-02 公開日 2018-07-04 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Mono- and Bivalent 14-3-3 Inhibitors for Characterizing Supramolecular "Lysine Wrapping" of Oligoethylene Glycol (OEG) Moieties in Proteins. Chemistry, 24, 2018
6G5I	Cryo-EM structure of a late human pre-40S ribosomal subunit - State R 分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R. 登録日 2018-03-29 公開日 2018-06-06 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Visualizing late states of human 40S ribosomal subunit maturation. Nature, 558, 2018
6GB0	The Structure of variant K294A of the Mo-insertase domain Cnx1E from Arabidopsis thaliana in complex with AMP 分子名称: 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, CHLORIDE ION, ... 著者 Krausze, J. 登録日 2018-04-13 公開日 2018-07-18 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.814 Å) 主引用文献 The functional principle of eukaryotic molybdenum insertases. Biochem. J., 475, 2018
6GBC	The Structure of variant R369A of the Mo-insertase domain Cnx1E from Arabidopsis thaliana in complex with AMP and molybdate 分子名称: 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, ... 著者 Krausze, J. 登録日 2018-04-13 公開日 2018-07-18 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 The functional principle of eukaryotic molybdenum insertases. Biochem. J., 475, 2018
6FNB	Mono- and bivalent 14-3-3 inhibitors for characterizing supramolecular lysine-PEG interactions in proteins 分子名称: 14-3-3 protein zeta/delta, BENZOIC ACID, CALCIUM ION, ... 著者 Bier, D, Ottmann, C. 登録日 2018-02-02 公開日 2018-07-04 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Mono- and Bivalent 14-3-3 Inhibitors for Characterizing Supramolecular "Lysine Wrapping" of Oligoethylene Glycol (OEG) Moieties in Proteins. Chemistry, 24, 2018
4N4S	A Double Mutant Rat Erk2 in Complex With a Pyrazolo[3,4-d]pyrimidine Inhibitor 分子名称: 3-[2-(benzyloxy)-8-methylquinolin-6-yl]-1-(propan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Mitogen-activated protein kinase 1 著者 Hari, S.B, Maly, D.J, Merritt, E.A. 登録日 2013-10-08 公開日 2014-04-16 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Conformation-Selective ATP-Competitive Inhibitors Control Regulatory Interactions and Noncatalytic Functions of Mitogen-Activated Protein Kinases. Chem.Biol., 21, 2014
3N9J	Structure of human Glutathione Transferase Pi class in complex with Ethacraplatin 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ... 著者 Parker, L.J, Parker, M.W. 登録日 2010-05-30 公開日 2011-05-11 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Studies of glutathione transferase P1-1 bound to a platinum(IV)-based anticancer compound reveal the molecular basis of its activation. To be Published
3ENU	Crystal structure of Nitrollin, a betagamma-crystallin from Nitrosospira multiformis 分子名称: Putative uncharacterized protein 著者 Aravind, P, Sankaranarayanan, R. 登録日 2008-09-26 公開日 2009-03-31 最終更新日 2017-10-25 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Three-dimensional domain swapping in nitrollin, a single-domain betagamma-crystallin from Nitrosospira multiformis, controls protein conformation and stability but not dimerization J.Mol.Biol., 385, 2009
6G53	Cryo-EM structure of a late human pre-40S ribosomal subunit - State E 分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R. 登録日 2018-03-28 公開日 2018-06-06 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Visualizing late states of human 40S ribosomal subunit maturation. Nature, 558, 2018
6G9X	Crystal structure of a MFS transporter at 2.54 Angstroem resolution 分子名称: 2-sulfanylbenzoic acid, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, MERCURY (II) ION, ... 著者 Kalbermatter, D, Bosshart, P, Bonetti, S, Fotiadis, D. 登録日 2018-04-11 公開日 2019-07-03 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Mechanistic basis of L-lactate transport in the SLC16 solute carrier family. Nat Commun, 10, 2019
6G9T	CRYSTAL STRUCTURE OF CMY-136 class C BETA-LACTAMASE 分子名称: Beta-lactamase, GLYCEROL, ISOPROPYL ALCOHOL, ... 著者 Zavala, A, Retailleau, P, Naas, T, Iorga, B. 登録日 2018-04-11 公開日 2019-02-27 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Genetic, Biochemical, and Structural Characterization of CMY-136 beta-Lactamase, a Peculiar CMY-2 Variant. Acs Infect Dis., 5, 2019
6GBF	The Structure of variant R369A of the Mo-insertase domain Cnx1E from Arabidopsis thaliana in complex with AMP 分子名称: 1,2-ETHANEDIOL, ACETATE ION, ADENOSINE MONOPHOSPHATE, ... 著者 Krausze, J. 登録日 2018-04-13 公開日 2018-07-18 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.712 Å) 主引用文献 The functional principle of eukaryotic molybdenum insertases. Biochem. J., 475, 2018

<153154155156157158159160161162163164165166167168>