6FPS

Crystal structure of 4-oxalocrotonate tautomerase triple mutant L8Y/M45Y/F50A

Summary for 6FPS

Entry DOI	10.2210/pdb6fps/pdb
Descriptor	2-hydroxymuconate tautomerase, PHOSPHATE ION, GLYCEROL, ... (4 entities in total)
Functional Keywords	2-hydroxymuconate tautomerase, isomerase
Biological source	Pseudomonas putida (Arthrobacter siderocapsulatus)
Total number of polymer chains	18
Total formula weight	123086.31
Authors	Pijning, T.,Thunnissen, A.M.W.H. (deposition date: 2018-02-12, release date: 2019-03-06, Last modification date: 2024-01-17)
Primary citation	Biewenga, L.,Saravanan, T.,Kunzendorf, A.,van der Meer, J.Y.,Pijning, T.,Tepper, P.G.,van Merkerk, R.,Charnock, S.J.,Thunnissen, A.W.H.,Poelarends, G.J. Enantioselective Synthesis of Pharmaceutically Active gamma-Aminobutyric Acids Using a Tailor-Made Artificial Michaelase in One-Pot Cascade Reactions. ACS Catal, 9:1503-1513, 2019 Cited by PubMed: 30740262 DOI: 10.1021/acscatal.8b04299 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation