PDB: 499 件ウェブページステータス検索Chemie searchBIRD

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2MJV	Solution structures of second bromodomain of Brd4 with di-acetylated Twist peptide 分子名称: Bromodomain-containing protein 4, Twist-related protein 1 著者 Zeng, L, Zhou, M. 登録日 2014-01-16 公開日 2014-03-19 最終更新日 2023-11-15 実験手法 SOLUTION NMR 主引用文献 Disrupting the Interaction of BRD4 with Diacetylated Twist Suppresses Tumorigenesis in Basal-like Breast Cancer. Cancer Cell, 25, 2014
4OC7	Retinoic acid receptor alpha in complex with (E)-3-(3'-allyl-6-hydroxy-[1,1'-biphenyl]-3-yl)acrylic acid and a fragment of the coactivator TIF2 分子名称: (2E)-3-[6-hydroxy-3'-(prop-2-en-1-yl)biphenyl-3-yl]prop-2-enoic acid, Nuclear receptor coactivator 2, Retinoic acid receptor RXR-alpha 著者 Leysen, S, Scheepstra, M, Brunsveld, L, Milroy, L.G, Ottmann, C. 登録日 2014-01-08 公開日 2014-10-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 A natural-product switch for a dynamic protein interface. Angew.Chem.Int.Ed.Engl., 53, 2014
4NQA	Crystal structure of liganded hRXR-alpha/hLXR-beta heterodimer on DNA 分子名称: (9cis)-retinoic acid, 5'-D(*TP*AP*AP*GP*GP*TP*CP*AP*CP*TP*TP*CP*AP*GP*GP*TP*CP*A)-3', 5'-D(*TP*AP*TP*GP*AP*CP*CP*TP*GP*AP*AP*GP*TP*GP*AP*CP*CP*T)-3', ... 著者 Lou, X.H, Toresson, G, Benod, C, Suh, J.H, Phillips, K.J, Webb, P, Gustafsson, J.A. 登録日 2013-11-24 公開日 2014-02-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.102 Å) 主引用文献 Structure of the retinoid X receptor alpha-liver X receptor beta (RXR alpha-LXR beta ) heterodimer on DNA. Nat.Struct.Mol.Biol., 21, 2014
2MH3	NMR structure of the basic helix-loop-helix region of the transcriptional repressor HES-1 分子名称: Transcription factor HES-1 著者 Wienk, H, Popovic, M, Coglievina, M, Boelens, R, Pongor, S, Pintar, A. 登録日 2013-11-15 公開日 2014-02-05 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 The basic helix-loop-helix region of the transcriptional repressor hairy and enhancer of split 1 is preorganized to bind DNA. Proteins, 82, 2014
2MH0	Solution NMR structure of the p300 Taz2:ETAD1 complex 分子名称: Histone acetyltransferase p300, Transcription factor E2-alpha 著者 Langelaan, D.N, Smith, S.P, Chitayat, S. 登録日 2013-11-12 公開日 2014-11-12 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structural insights into TAZ2 domain-mediated CBP/p300 recruitment by transactivation domain 1 of the lymphopoietic transcription factor E2A. J.Biol.Chem., 295, 2020
4C7N	Crystal Structure of the synthetic peptide iM10 in complex with the coiled-coil region of MITF 分子名称: MERCURY (II) ION, MICROPHTHALMIA ASSOCIATED TRANSCRIPTION FACTOR, SYNTHETIC ALPHA-HELIX, ... 著者 Wohlwend, D, Gerhardt, S, Kuekenshoener, T, Einsle, O. 登録日 2013-09-23 公開日 2014-04-02 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Improving Coiled Coil Stability While Maintaining Specificity by a Bacterial Hitchhiker Selection System. J.Struct.Biol., 186, 2014
4MGC	Crystal structure of hERa-LBD (Y537S) in complex with benzophenone-2 分子名称: Estrogen receptor, GLYCEROL, Nuclear receptor coactivator 1, ... 著者 Delfosse, V, Grimaldi, M, Bourguet, W. 登録日 2013-08-28 公開日 2014-09-03 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structural and functional profiling of environmental ligands for estrogen receptors. Environ.Health Perspect., 122, 2014
4MG6	Crystal structure of hERa-LBD (Y537S) in complex with benzylbutylphtalate 分子名称: Estrogen receptor, GLYCEROL, Nuclear receptor coactivator 1, ... 著者 Delfosse, V, Grimaldi, M, Bourguet, W. 登録日 2013-08-28 公開日 2014-09-03 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural and functional profiling of environmental ligands for estrogen receptors. Environ.Health Perspect., 122, 2014
4MGA	Crystal structure of hERa-LBD (Y537S) in complex with 4-tert-octylphenol 分子名称: 4-(2,4,4-trimethylpentan-2-yl)phenol, Estrogen receptor, Nuclear receptor coactivator 1 著者 Delfosse, V, Grimaldi, M, Bourguet, W. 登録日 2013-08-28 公開日 2014-09-03 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural and functional profiling of environmental ligands for estrogen receptors. Environ.Health Perspect., 122, 2014
4MG5	Crystal structure of hERa-LBD (Y537S) in complex with chlordecone 分子名称: Estrogen receptor, GLYCEROL, Nuclear receptor coactivator 1, ... 著者 Delfosse, V, Grimaldi, M, Bourguet, W. 登録日 2013-08-28 公開日 2014-09-03 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structural and functional profiling of environmental ligands for estrogen receptors. Environ.Health Perspect., 122, 2014
4MGB	Crystal structure of hERa-LBD (Y537S) in complex with TCBPA 分子名称: 4,4'-propane-2,2-diylbis(2,6-dichlorophenol), Estrogen receptor, GLYCEROL, ... 著者 Delfosse, V, Grimaldi, M, Bourguet, W. 登録日 2013-08-28 公開日 2014-09-03 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structural and functional profiling of environmental ligands for estrogen receptors. Environ.Health Perspect., 122, 2014
4MG8	Crystal structure of hERa-LBD (Y537S) in complex with alpha-zearalanol 分子名称: 1,2-ETHANEDIOL, Estrogen receptor, GLYCEROL, ... 著者 Delfosse, V, Grimaldi, M, Bourguet, W. 登録日 2013-08-28 公開日 2014-09-03 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structural and functional profiling of environmental ligands for estrogen receptors. Environ.Health Perspect., 122, 2014
4MG9	Crystal structure of hERa-LBD (Y537S) in complex with butylparaben 分子名称: Estrogen receptor, GLYCEROL, Nuclear receptor coactivator 1, ... 著者 Delfosse, V, Grimaldi, M, Bourguet, W. 登録日 2013-08-28 公開日 2014-09-03 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural and functional profiling of environmental ligands for estrogen receptors. Environ.Health Perspect., 122, 2014
4MG7	Crystal structure of hERa-LBD (Y537S) in complex with ferutinine 分子名称: 1,2-ETHANEDIOL, Estrogen receptor, Nuclear receptor coactivator 1, ... 著者 Delfosse, V, Grimaldi, M, Bourguet, W. 登録日 2013-08-28 公開日 2014-09-03 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structural and functional profiling of environmental ligands for estrogen receptors. Environ.Health Perspect., 122, 2014
4MGD	Crystal structure of hERa-LBD (Y537S) in complex with HPTE 分子名称: 1,2-ETHANEDIOL, 4,4'-(2,2,2-trichloroethane-1,1-diyl)diphenol, Estrogen receptor, ... 著者 Delfosse, V, Grimaldi, M, Bourguet, W. 登録日 2013-08-28 公開日 2014-09-03 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural and functional profiling of environmental ligands for estrogen receptors. Environ.Health Perspect., 122, 2014
4M8H	CRYSTAL STRUCTURE OF HUMAN RETINOID X RECEPTOR ALPHA-LIGAND BINDING DOMAIN COMPLEX WITH (R)4-METHYL 9cUAB30 AND COACTIVATOR PEPTIDE GRIP-1 分子名称: (2E,6Z,8E)-3,7-dimethyl-8-[(4R)-4-methyl-3,4-dihydronaphthalen-1(2H)-ylidene]octa-2,6-dienoic acid, Nuclear receptor coactivator 2, Retinoic acid receptor RXR-alpha 著者 Xia, G, Smith, C.D, Muccio, D.D. 登録日 2013-08-13 公開日 2014-01-22 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Methyl-substituted conformationally constrained rexinoid agonists for the retinoid X receptors demonstrate improved efficacy for cancer therapy and prevention. Bioorg.Med.Chem., 22, 2014
4M8E	CRYSTAL STRUCTURE OF HUMAN RETINOID X RECEPTOR ALPHA-LIGAND BINDING DOMAIN COMPLEX WITH (S) 4-Methyl 9cUAB30 COACTIVATOR PEPTIDE GRIP-1 分子名称: (3E,6Z,8E)-3,7-dimethyl-8-[(4S)-4-methyl-3,4-dihydronaphthalen-1(2H)-ylidene]octa-3,6-dienoic acid, Nuclear receptor coactivator 2, Retinoic acid receptor RXR-alpha 著者 Xia, G, Smith, C.D, Muccio, D.D. 登録日 2013-08-13 公開日 2014-01-22 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Methyl-substituted conformationally constrained rexinoid agonists for the retinoid X receptors demonstrate improved efficacy for cancer therapy and prevention. Bioorg.Med.Chem., 22, 2014
4M4X	Structure and Dimerization Properties of the Aryl Hydrocarbon Receptor (AHR) PAS-A Domain 分子名称: Aryl hydrocarbon receptor 著者 Wu, D, Potluri, N, Kim, Y, Rastinejad, F. 登録日 2013-08-07 公開日 2013-09-18 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.551 Å) 主引用文献 Structure and dimerization properties of the aryl hydrocarbon receptor PAS-A domain. Mol.Cell.Biol., 33, 2013
4LPZ	ARNT transcription factor/coactivator complex 分子名称: Aryl hydrocarbon receptor nuclear translocator, Transforming acidic coiled-coil-containing protein 3 著者 Guo, Y, Scheuermann, T.H, Gardner, K.H. 登録日 2013-07-16 公開日 2014-07-16 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Coiled-coil coactivators play a structural role mediating interactions in hypoxia-inducible factor heterodimerization. J.Biol.Chem., 290, 2015
4KFZ	Crystal structure of LMO2 and anti-LMO2 VH complex 分子名称: Anti-LMO2 VH, LMO-2, ZINC ION 著者 Sewell, H, Tanaka, T, El Omari, K, Cruz-Migoni, A, Mancini, E.J, Fuentes-Fernandez, N, Chambers, J, Rabbitts, T.H. 登録日 2013-04-28 公開日 2014-01-22 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Conformational flexibility of the oncogenic protein LMO2 primes the formation of the multi-protein transcription complex. Sci Rep, 4, 2014
4K6I	Crystal structure of human retinoid X receptor alpha-ligand binding domain complex with Targretin and the coactivator peptide GRIP-1 分子名称: 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethenyl]benzoic acid, Nuclear receptor coactivator 2, Retinoic acid receptor RXR-alpha 著者 Xia, G, Smith, C.D, Muccio, D.D. 登録日 2013-04-15 公開日 2013-11-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Defining the Communication between Agonist and Coactivator Binding in the Retinoid X Receptor alpha Ligand Binding Domain. J.Biol.Chem., 289, 2014
4K4J	Crystal structure of human Retinoid X Receptor alpha-ligand binding domain complex with 9cUAB30 and the coactivator peptide GRIP-1 分子名称: (2E,4E,6Z,8E)-8-(3,4-dihydronaphthalen-1(2H)-ylidene)-3,7-dimethylocta-2,4,6-trienoic acid, Nuclear receptor coactivator 2 peptide, Retinoic acid receptor RXR-alpha 著者 Xia, G, Smith, C.D, Muccio, D.D. 登録日 2013-04-12 公開日 2013-11-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Defining the Communication between Agonist and Coactivator Binding in the Retinoid X Receptor alpha Ligand Binding Domain. J.Biol.Chem., 289, 2014
4JOL	Complex structure of AML1-ETO NHR2 domain with HEB fragment 分子名称: Protein CBFA2T1, Transcription factor 12 著者 Wang, Z, Patel, D.J. 登録日 2013-03-18 公開日 2013-06-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.906 Å) 主引用文献 A stable transcription factor complex nucleated by oligomeric AML1-ETO controls leukaemogenesis. Nature, 500, 2013
4J5X	Crystal Structure of the SR12813-bound PXR/RXRalpha LBD Heterotetramer Complex 分子名称: Nuclear receptor subfamily 1 group I member 2, Nuclear receptor coactivator 1, Retinoic acid receptor RXR-alpha, ... 著者 Wallace, B.D, Betts, L, Redinbo, M.R. 登録日 2013-02-10 公開日 2013-08-21 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural and Functional Analysis of the Human Nuclear Xenobiotic Receptor PXR in Complex with RXRalpha. J.Mol.Biol., 425, 2013
4J5W	Crystal Structure of the apo-PXR/RXRalpha LBD Heterotetramer Complex 分子名称: MAGNESIUM ION, Nuclear receptor subfamily 1 group I member 2, Nuclear receptor coactivator 1, ... 著者 Wallace, B.D, Betts, L, Redinbo, M.R. 登録日 2013-02-10 公開日 2013-08-21 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural and Functional Analysis of the Human Nuclear Xenobiotic Receptor PXR in Complex with RXRalpha. J.Mol.Biol., 425, 2013

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