4MG6

Crystal structure of hERa-LBD (Y537S) in complex with benzylbutylphtalate

Summary for 4MG6

Entry DOI	10.2210/pdb4mg6/pdb
Related	3UU7 3UUA 3UUC 3UUD 4MG5 4MG7 4MG8 4MG9 4MGA 4MGB 4MGC 4MGD
Descriptor	Estrogen receptor, Nuclear receptor coactivator 1, benzyl butyl benzene-1,2-dicarboxylate, ... (5 entities in total)
Functional Keywords	ligand-binding domain of nuclear hormone receptor, hormone receptor
Biological source	Homo sapiens (human) More
Cellular location	Isoform 1: Nucleus . Isoform 3: Nucleus. Nucleus: P03372 Nucleus : Q15788
Total number of polymer chains	4
Total formula weight	62041.01
Authors	Delfosse, V.,Grimaldi, M.,Bourguet, W. (deposition date: 2013-08-28, release date: 2014-09-03, Last modification date: 2023-12-06)
Primary citation	Delfosse, V.,Grimaldi, M.,Cavailles, V.,Balaguer, P.,Bourguet, W. Structural and functional profiling of environmental ligands for estrogen receptors. Environ.Health Perspect., 122:1306-1313, 2014 Cited by PubMed: 25260197 DOI: 10.1289/ehp.1408453 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation