7L67
 
 | |
7NL7
 | | Crystal Structure of DC-SIGN in complex with a triazole-based glycomimetic ligand | | 分子名称: | 3-Aminopropyl 2-deoxy-2-(4-phenyl-1,2,3-triazol-1-yl)-alpha-D-mannopyranoside, CALCIUM ION, DC-SIGN, ... | | 著者 | Jakob, R.P, Cramer, J, Lakkaichi, A, Aliu, B, Cattaneo, I, Klein, S, Jiang, X, Rabbani, S, Schwardt, O, Ernst, B, Maier, T. | | 登録日 | 2021-02-22 | | 公開日 | 2021-10-27 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Sweet Drugs for Bad Bugs: A Glycomimetic Strategy against the DC-SIGN-Mediated Dissemination of SARS-CoV-2.
J.Am.Chem.Soc., 143, 2021
|
|
7NL6
 | | Crystal Structure of DC-SIGN in complex with a triazole-based glycomimetic ligand | | 分子名称: | CALCIUM ION, DC-SIGN, CRD domain, ... | | 著者 | Jakob, R.P, Cramer, J, Lakkaichi, A, Aliu, B, Cattaneo, I, Klein, S, Jiang, X, Rabbani, S, Schwardt, O, Ernst, B, Maier, T. | | 登録日 | 2021-02-22 | | 公開日 | 2021-10-27 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Sweet Drugs for Bad Bugs: A Glycomimetic Strategy against the DC-SIGN-Mediated Dissemination of SARS-CoV-2.
J.Am.Chem.Soc., 143, 2021
|
|
7ODU
 | | Natural killer cell receptor NKR-P1B from Rattus norvegicus in complex with its cognate ligand Clr-11 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C-type lectin domain family 2 member D11, ... | | 著者 | Skalova, T, Blaha, J, Kalouskova, B, Skorepa, O, Vanek, O, Dohnalek, J. | | 登録日 | 2021-04-30 | | 公開日 | 2022-06-01 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Natural killer cell receptor NKR-P1B from Rattus norvegicus in complex with its cognate ligand Clr-11
To Be Published
|
|
7R8U
 | |
7FI6
 | | Crystal structure of human MICA mutants in complex with natural killer cell receptor NKG2D | | 分子名称: | MHC class I polypeptide-related sequence A, NKG2-D type II integral membrane protein | | 著者 | Cai, W, Peng, S, Xu, T, Tian, Y, Li, Y, Liu, J. | | 登録日 | 2021-07-30 | | 公開日 | 2022-08-31 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal structure of human MICA mutants in complex with natural killer cell receptor NKG2D
to be published
|
|
7FI7
 | | Crystal structure of human MICA mutants in complex with natural killer cell receptor NKG2D | | 分子名称: | MHC class I polypeptide-related sequence A, NKG2-D type II integral membrane protein | | 著者 | Cai, W, Peng, S, Xu, T, Tian, Y, Li, Y, Liu, J. | | 登録日 | 2021-07-30 | | 公開日 | 2022-08-31 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.78 Å) | | 主引用文献 | Crystal structure of human MICA mutants in complex with natural killer cell receptor NKG2D
to be published
|
|
7FI8
 | | Crystal structure of human MICA mutants in complex with natural killer cell receptor NKG2D | | 分子名称: | MHC class I polypeptide-related sequence A, NKG2-D type II integral membrane protein | | 著者 | Cai, W, Peng, S, Xu, T, Tian, Y, Li, Y, Liu, J. | | 登録日 | 2021-07-30 | | 公開日 | 2022-08-31 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure of human MICA mutants in complex with natural killer cell receptor NKG2D
to be published
|
|
7FI9
 | | Crystal structure of human MICA mutants in complex with natural killer cell receptor NKG2D | | 分子名称: | GLYCEROL, MHC class I polypeptide-related sequence A, NKG2-D type II integral membrane protein | | 著者 | Cai, W, Peng, S, Xu, T, Tian, Y, Li, Y, Liu, J. | | 登録日 | 2021-07-30 | | 公開日 | 2022-08-31 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | | 主引用文献 | Crystal structure of human MICA mutants in complex with natural killer cell receptor NKG2D
to be published
|
|
7FI5
 | | Crystal structure of human MICA mutants in complex with natural killer cell receptor NKG2D | | 分子名称: | GLYCEROL, MHC class I polypeptide-related sequence A, NKG2-D type II integral membrane protein | | 著者 | Cai, W, Peng, S, Xu, T, Tian, Y, Li, Y, Liu, J. | | 登録日 | 2021-07-30 | | 公開日 | 2022-08-31 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | | 主引用文献 | Crystal structure of human MICA mutants in complex with natural killer cell receptor NKG2D
to be published
|
|
7QAJ
 | | ZK002 with Anti-angiogenic and Anti-inflamamtory Properties | | 分子名称: | SULFATE ION, Snaclec clone 2100755 alpha, Snaclec clone 2100755 beta | | 著者 | Wong, W.Y, Chan, B.D, Muk Lan Lee, M, Dai, X, Tsim, K.W.K, Hsiao, W.L.W, Li, M, Li, X.Y, Tai, W.C.S. | | 登録日 | 2021-11-17 | | 公開日 | 2023-06-14 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Isolation and characterization of ZK002, a novel dual function snake venom protein from Deinagkistrodon acutus with anti-angiogenic and anti-inflammatory properties.
Front Pharmacol, 14, 2023
|
|
7W5D
 | |
7T4R
 | | CryoEM structure of the HCMV Pentamer gH/gL/UL128/UL130/UL131A in complex with THBD and neutralizing fabs MSL-109 and 13H11 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein H, Envelope glycoprotein L, ... | | 著者 | Kschonsak, M, Johnson, M.C, Schelling, R, Green, E.M, Rouge, L, Ho, H, Patel, N, Kilic, C, Kraft, E, Arthur, C.P, Rohou, A.L, Comps-Agrar, L, Martinez-Martin, N, Perez, L, Payandeh, J, Ciferri, C. | | 登録日 | 2021-12-10 | | 公開日 | 2022-03-23 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural basis for HCMV Pentamer receptor recognition and antibody neutralization.
Sci Adv, 8, 2022
|
|
7QSR
 | | CryoEM structure of the Ectodomain of Human PLA2R | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Secretory phospholipase A2 receptor, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Briggs, D.C, Lockhart-Cairns, M.P, Baldock, C. | | 登録日 | 2022-01-14 | | 公開日 | 2022-07-20 | | 最終更新日 | 2022-08-03 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structure of PLA2R reveals presentation of the dominant membranous nephropathy epitope and an immunogenic patch.
Proc.Natl.Acad.Sci.USA, 119, 2022
|
|
7WZ8
 | |
7XMP
 | |
8A59
 | | C-type lectin-like domain (CTLD) and Sushi-like domain of human CD93 | | 分子名称: | Complement component C1q receptor, GLYCEROL, SULFATE ION | | 著者 | Tassone, G, Barbera, S, Raucci, L, Orlandini, M, Pozzi, C. | | 登録日 | 2022-06-14 | | 公開日 | 2022-11-02 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | Dimerization of the C-type lectin-like receptor CD93 promotes its binding to Multimerin-2 in endothelial cells.
Int.J.Biol.Macromol., 224, 2023
|
|
7Y5N
 | | Structure of 1:1 PAPP-A.ProMBP complex(half map) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Bone marrow proteoglycan, ... | | 著者 | Zhong, Q.H, Chu, H.L, Wang, G.P, Zhang, C, Wei, Y, Qiao, J, Hang, J. | | 登録日 | 2022-06-17 | | 公開日 | 2023-01-11 | | 実験手法 | ELECTRON MICROSCOPY (3.45 Å) | | 主引用文献 | Structural insights into the covalent regulation of PAPP-A activity by proMBP and STC2.
Cell Discov, 8, 2022
|
|
7YTQ
 | |
8EA9
 | | NKG2D complexed with inhibitor 4d | | 分子名称: | DI(HYDROXYETHYL)ETHER, N-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]-2-(dimethylamino)-2-oxoethyl]-4-[4-(trifluoromethyl)phenyl]pyridine-3-carboxamide, NKG2-D type II integral membrane protein, ... | | 著者 | Thompson, A.A, Grant, J.C, Karpowich, N.K, Sharma, S. | | 登録日 | 2022-08-28 | | 公開日 | 2023-05-03 | | 最終更新日 | 2023-05-10 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | Identification of small-molecule protein-protein interaction inhibitors for NKG2D.
Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
8EA6
 | | NKG2D complexed with inhibitor 3e | | 分子名称: | N-{(1S)-2-(dimethylamino)-2-oxo-1-[3-(trifluoromethyl)phenyl]ethyl}-4'-(trifluoromethyl)[1,1'-biphenyl]-2-carboxamide, NKG2-D type II integral membrane protein | | 著者 | Thompson, A.A, Grant, J.C, Karpowich, N.K, Sharma, S. | | 登録日 | 2022-08-28 | | 公開日 | 2023-05-03 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | Identification of small-molecule protein-protein interaction inhibitors for NKG2D.
Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
8EA5
 | | NKG2D complexed with inhibitor 1a | | 分子名称: | (3S,5aS,8aR)-3-benzyl-6-[(3,5-dichlorophenyl)methyl]-1,4-dimethyloctahydropyrrolo[3,2-e][1,4]diazepine-2,5-dione, NKG2-D type II integral membrane protein, TRIETHYLENE GLYCOL | | 著者 | Thompson, A.A, Grant, J.C, Karpowich, N.K, Sharma, S. | | 登録日 | 2022-08-28 | | 公開日 | 2023-05-03 | | 最終更新日 | 2023-05-10 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | Identification of small-molecule protein-protein interaction inhibitors for NKG2D.
Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
8EA8
 | | NKG2D complexed with inhibitor 4a | | 分子名称: | DI(HYDROXYETHYL)ETHER, N-{(1S)-2-(dimethylamino)-2-oxo-1-[3-(trifluoromethyl)phenyl]ethyl}-4-[4-(trifluoromethyl)phenyl]pyridine-3-carboxamide, NKG2-D type II integral membrane protein, ... | | 著者 | Thompson, A.A, Grant, J.C, Karpowich, N.K, Sharma, S. | | 登録日 | 2022-08-28 | | 公開日 | 2023-05-03 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | Identification of small-molecule protein-protein interaction inhibitors for NKG2D.
Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
8EA7
 | | NKG2D complexed with inhibitor 3g | | 分子名称: | (4M)-N-{(1S)-2-(dimethylamino)-2-oxo-1-[3-(trifluoromethyl)phenyl]ethyl}-4-(1-methyl-1H-pyrazol-5-yl)-4'-(trifluoromethyl)[1,1'-biphenyl]-2-carboxamide, DI(HYDROXYETHYL)ETHER, NKG2-D type II integral membrane protein | | 著者 | Thompson, A.A, Grant, J.C, Karpowich, N.K, Sharma, S. | | 登録日 | 2022-08-28 | | 公開日 | 2023-05-03 | | 最終更新日 | 2023-05-10 | | 実験手法 | X-RAY DIFFRACTION (1.28 Å) | | 主引用文献 | Identification of small-molecule protein-protein interaction inhibitors for NKG2D.
Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
8EAB
 | | NKG2D complexed with inhibitor 4f | | 分子名称: | DI(HYDROXYETHYL)ETHER, N-[(1S)-2-oxo-1-[3-(trifluoromethyl)phenyl]-2-({4-[4-(trifluoromethyl)phenyl]pyridin-3-yl}amino)ethyl]-4-[4-(trifluoromethyl)phenyl]pyridine-3-carboxamide, NKG2-D type II integral membrane protein | | 著者 | Thompson, A.A, Grant, J.C, Karpowich, N.K, Sharma, S. | | 登録日 | 2022-08-28 | | 公開日 | 2023-05-03 | | 最終更新日 | 2023-05-10 | | 実験手法 | X-RAY DIFFRACTION (1.44 Å) | | 主引用文献 | Identification of small-molecule protein-protein interaction inhibitors for NKG2D.
Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
