6TCH
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5NCR
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![BU of 5ncr by Molmil](/molmil-images/mine/5ncr) | OH1 from the Orf virus: a tyrosine phosphatase that displays distinct structural features and triple substrate specificity | 分子名称: | PHOSPHATE ION, SULFATE ION, tyrosine phosphatase | 著者 | Segovia, D, Haouz, A, Berois, M, Villarino, A, Andre-Leroux, G. | 登録日 | 2017-03-06 | 公開日 | 2017-08-09 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | OH1 from Orf Virus: A New Tyrosine Phosphatase that Displays Distinct Structural Features and Triple Substrate Specificity. J. Mol. Biol., 429, 2017
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5H2P
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![BU of 5h2p by Molmil](/molmil-images/mine/5h2p) | A three dimensional movie of structural changes in bacteriorhodopsin: structure obtained 657 us after photoexcitation | 分子名称: | 2,3-DI-PHYTANYL-GLYCEROL, Bacteriorhodopsin, DECANE, ... | 著者 | Royant, A, Nango, E, Nakane, T, Tanaka, T, Arima, T, Neutze, R, Iwata, S. | 登録日 | 2016-10-15 | 公開日 | 2016-12-21 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A three-dimensional movie of structural changes in bacteriorhodopsin Science, 354, 2016
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5GRJ
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![BU of 5grj by Molmil](/molmil-images/mine/5grj) | Crystal structure of human PD-L1 with monoclonal antibody avelumab | 分子名称: | Programmed cell death 1 ligand 1, avelumab H chain, avelumab L chain | 著者 | Liu, K, Tan, S, Chai, Y, Chen, D, Song, H, Zhang, C.W.-H, Shi, Y, Liu, J, Tan, W, Lyu, J, Gao, S, Yan, J, Qi, J, Gao, G.F. | 登録日 | 2016-08-11 | 公開日 | 2016-11-02 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.206 Å) | 主引用文献 | Structural basis of anti-PD-L1 monoclonal antibody avelumab for tumor therapy. Cell Res., 27, 2017
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5H54
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![BU of 5h54 by Molmil](/molmil-images/mine/5h54) | Mdm12 from K. lactis 1-239 | 分子名称: | Mitochondrial distribution and morphology protein 12 | 著者 | Kawano, S, Quinbara, S, Endo, T. | 登録日 | 2016-11-04 | 公開日 | 2017-11-08 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structure-function insights into direct lipid transfer between membranes by Mmm1-Mdm12 of ERMES J. Cell Biol., 217, 2018
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5N1C
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5GVB
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![BU of 5gvb by Molmil](/molmil-images/mine/5gvb) | SepB domain of human AND-1 | 分子名称: | WD repeat and HMG-box DNA-binding protein 1 | 著者 | Guan, C.C, Li, J. | 登録日 | 2016-09-05 | 公開日 | 2017-04-19 | 最終更新日 | 2017-06-21 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | The structure and polymerase-recognition mechanism of the crucial adaptor protein AND-1 in the human replisome. J. Biol. Chem., 292, 2017
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5N5W
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![BU of 5n5w by Molmil](/molmil-images/mine/5n5w) | 14-3-3 sigma in complex with TAZ pS89 peptide and fragment NV3 | 分子名称: | 14-3-3 protein sigma, 4-[3,5-bis(chloranyl)pyridin-2-yl]oxyaniline, CALCIUM ION, ... | 著者 | Sijbesma, E, Leysen, S, Ottmann, C. | 登録日 | 2017-02-14 | 公開日 | 2017-07-19 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | 主引用文献 | Identification of Two Secondary Ligand Binding Sites in 14-3-3 Proteins Using Fragment Screening. Biochemistry, 56, 2017
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5GLW
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![BU of 5glw by Molmil](/molmil-images/mine/5glw) | Tl-gal with LacNAc | 分子名称: | beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, galectin | 著者 | Jang, S.B, Hwang, E.Y. | 登録日 | 2016-07-12 | 公開日 | 2016-11-09 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural Basis for Carbohydrate Recognition and Anti-inflammatory Modulation by Gastrointestinal Nematode Parasite Toxascaris leonina Galectin J. Biol. Chem., 291, 2016
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6JLF
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6JEZ
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![BU of 6jez by Molmil](/molmil-images/mine/6jez) | Covalent labeling of rVDR-LBD by turn-on fluorescent probe mediated by conjugate addition and cyclization | 分子名称: | (1R,3R)-5-(2-((1R,3aS,7aR,E)-1-((R)-6-hydroxy-6-methylheptan-2-yl)-7a-methyloctahydro-4H-inden-4-ylidene)ethylidene)-2- methylenecyclohexane-1,3-diol, 7-(diethylamino)chromen-2-one, Mediator of RNA polymerase II transcription subunit 1, ... | 著者 | Kojima, H, Yamamoto, K, Itoh, T. | 登録日 | 2019-02-07 | 公開日 | 2020-02-12 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Cyclization Reaction-Based Turn-on Probe for Covalent Labeling of Target Proteins. Cell Chem Biol, 27, 2020
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6TOM
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![BU of 6tom by Molmil](/molmil-images/mine/6tom) | Crystal structure of human BCL6 BTB domain in complex with compound 1 | 分子名称: | 1,2-ETHANEDIOL, 5-[[2-[(3~{S},5~{R})-4,4-bis(fluoranyl)-3,5-dimethyl-piperidin-1-yl]-5-chloranyl-pyrimidin-4-yl]amino]-1-methyl-3-(3-methyl-3-oxidanyl-butyl)benzimidazol-2-one, B-cell lymphoma 6 protein | 著者 | Rodrigues, M.J, Le Bihan, Y.-V, van Montfort, R.L.M. | 登録日 | 2019-12-11 | 公開日 | 2020-04-22 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | AchievingIn VivoTarget Depletion through the Discovery and Optimization of Benzimidazolone BCL6 Degraders. J.Med.Chem., 63, 2020
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5GMM
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5H2H
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![BU of 5h2h by Molmil](/molmil-images/mine/5h2h) | A three dimensional movie of structural changes in bacteriorhodopsin: structure obtained 40 ns after photoexcitation | 分子名称: | 2,3-DI-PHYTANYL-GLYCEROL, Bacteriorhodopsin, DECANE, ... | 著者 | Royant, A, Nango, E, Nakane, T, Tanaka, T, Arima, T, Neutze, R, Iwata, S. | 登録日 | 2016-10-15 | 公開日 | 2016-12-21 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A three-dimensional movie of structural changes in bacteriorhodopsin Science, 354, 2016
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5NCL
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![BU of 5ncl by Molmil](/molmil-images/mine/5ncl) | Crystal structure of the Cbk1-Mob2 kinase-coactivator complex with an SSD1 peptide | 分子名称: | CBK1 kinase activator protein MOB2, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Protein SSD1, ... | 著者 | Gogl, G, Remenyi, A, Parker, B, Weiss, E. | 登録日 | 2017-03-06 | 公開日 | 2018-05-16 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | Ndr/Lats Kinases Bind Specific Mob-Family Coactivators through a Conserved and Modular Interface. Biochemistry, 2020
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6JHB
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5GKY
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![BU of 5gky by Molmil](/molmil-images/mine/5gky) | Structure of RyR1 in a closed state (C1 conformer) | 分子名称: | Peptidyl-prolyl cis-trans isomerase FKBP1A, Ryanodine receptor 1, ZINC ION | 著者 | Bai, X.C, Yan, Z, Wu, J.P, Yan, N. | 登録日 | 2016-07-07 | 公開日 | 2016-08-24 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | The Central domain of RyR1 is the transducer for long-range allosteric gating of channel opening Cell Res., 26, 2016
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6T38
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![BU of 6t38 by Molmil](/molmil-images/mine/6t38) | Pseudomonas aeruginosa RmlA in complex with allosteric inhibitor | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, BROMIDE ION, CHLORIDE ION, ... | 著者 | Alphey, M.S, Xiao, G, Westwood, J.N. | 登録日 | 2019-10-10 | 公開日 | 2020-08-19 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Next generation Glucose-1-phosphate thymidylyltransferase (RmlA) inhibitors: An extended SAR study to direct future design. Bioorg.Med.Chem., 50, 2021
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7BBD
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![BU of 7bbd by Molmil](/molmil-images/mine/7bbd) | Crystal structure of monoubiquitinated TRIM21 RING (Ub-RING) In complex with ubiquitin charged Ube2N (Ube2N~Ub) and Ube2V2 | 分子名称: | Polyubiquitin-B,E3 ubiquitin-protein ligase TRIM21, Polyubiquitin-C, Ubiquitin-conjugating enzyme E2 N, ... | 著者 | Kiss, L, Neuhaus, D, James, L.C. | 登録日 | 2020-12-17 | 公開日 | 2021-01-27 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | RING domains act as both substrate and enzyme in a catalytic arrangement to drive self-anchored ubiquitination. Nat Commun, 12, 2021
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6T3Y
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![BU of 6t3y by Molmil](/molmil-images/mine/6t3y) | Improved High Resolution Structure of MHC Class II complex | 分子名称: | ACETATE ION, GLYCEROL, MHC class II alpha chain, ... | 著者 | Halabi, S, Moncrieffe, M.C, Kaufman, J. | 登録日 | 2019-10-11 | 公開日 | 2020-11-25 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The dominantly expressed class II molecule from a resistant MHC haplotype presents only a few Marek's disease virus peptides by using an unprecedented binding motif. Plos Biol., 19, 2021
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5GRH
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6HFO
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![BU of 6hfo by Molmil](/molmil-images/mine/6hfo) | Human Hsp90 co-chaperone TTC4 C-domain | 分子名称: | PHOSPHATE ION, Tetratricopeptide repeat protein 4 | 著者 | Huber, E.M, Groll, M. | 登録日 | 2018-08-21 | 公開日 | 2019-03-27 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | The Co-chaperone Cns1 and the Recruiter Protein Hgh1 Link Hsp90 to Translation Elongation via Chaperoning Elongation Factor 2. Mol.Cell, 74, 2019
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5H3T
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![BU of 5h3t by Molmil](/molmil-images/mine/5h3t) | m7G cap bound to GEMIN5-WD | 分子名称: | 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, GLYCEROL, Gem-associated protein 5 | 著者 | Bharath, S.R, Tang, X, Song, H. | 登録日 | 2016-10-27 | 公開日 | 2016-12-28 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.571 Å) | 主引用文献 | Structural basis for specific recognition of pre-snRNA by Gemin5 Cell Res., 26, 2016
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7BVY
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7BXZ
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