PDB: 45459 件ウェブページステータス検索Chemie searchBIRD

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6TCH	Binary complex of 14-3-3 sigma and a high-affinity non-canonical 9-mer peptide binder 分子名称: 14-3-3 protein sigma, CHLORIDE ION, DLY-NVA-PPN-KCJ-SEP-PPN-B3S-BAL-PPN-LYS, ... 著者 Somsen, B.A, Ottmann, C. 登録日 2019-11-06 公開日 2020-07-01 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.801 Å) 主引用文献 Ultra-large chemical libraries for the discovery of high-affinity peptide binders. Nat Commun, 11, 2020
5NCR	OH1 from the Orf virus: a tyrosine phosphatase that displays distinct structural features and triple substrate specificity 分子名称: PHOSPHATE ION, SULFATE ION, tyrosine phosphatase 著者 Segovia, D, Haouz, A, Berois, M, Villarino, A, Andre-Leroux, G. 登録日 2017-03-06 公開日 2017-08-09 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 OH1 from Orf Virus: A New Tyrosine Phosphatase that Displays Distinct Structural Features and Triple Substrate Specificity. J. Mol. Biol., 429, 2017
5H2P	A three dimensional movie of structural changes in bacteriorhodopsin: structure obtained 657 us after photoexcitation 分子名称: 2,3-DI-PHYTANYL-GLYCEROL, Bacteriorhodopsin, DECANE, ... 著者 Royant, A, Nango, E, Nakane, T, Tanaka, T, Arima, T, Neutze, R, Iwata, S. 登録日 2016-10-15 公開日 2016-12-21 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 A three-dimensional movie of structural changes in bacteriorhodopsin Science, 354, 2016
5GRJ	Crystal structure of human PD-L1 with monoclonal antibody avelumab 分子名称: Programmed cell death 1 ligand 1, avelumab H chain, avelumab L chain 著者 Liu, K, Tan, S, Chai, Y, Chen, D, Song, H, Zhang, C.W.-H, Shi, Y, Liu, J, Tan, W, Lyu, J, Gao, S, Yan, J, Qi, J, Gao, G.F. 登録日 2016-08-11 公開日 2016-11-02 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.206 Å) 主引用文献 Structural basis of anti-PD-L1 monoclonal antibody avelumab for tumor therapy. Cell Res., 27, 2017
5H54	Mdm12 from K. lactis 1-239 分子名称: Mitochondrial distribution and morphology protein 12 著者 Kawano, S, Quinbara, S, Endo, T. 登録日 2016-11-04 公開日 2017-11-08 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structure-function insights into direct lipid transfer between membranes by Mmm1-Mdm12 of ERMES J. Cell Biol., 217, 2018
5N1C	Iodinated form of the Mycobacterium tuberculosis repressor EthR2 分子名称: IODIDE ION, Probable transcriptional regulatory protein 著者 Wintjens, R, Wohlkonig, A. 登録日 2017-02-06 公開日 2017-04-26 最終更新日 2023-03-01 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Reversion of antibiotic resistance in Mycobacterium tuberculosis by spiroisoxazoline SMARt-420. Science, 355, 2017
5GVB	SepB domain of human AND-1 分子名称: WD repeat and HMG-box DNA-binding protein 1 著者 Guan, C.C, Li, J. 登録日 2016-09-05 公開日 2017-04-19 最終更新日 2017-06-21 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 The structure and polymerase-recognition mechanism of the crucial adaptor protein AND-1 in the human replisome. J. Biol. Chem., 292, 2017
5N5W	14-3-3 sigma in complex with TAZ pS89 peptide and fragment NV3 分子名称: 14-3-3 protein sigma, 4-[3,5-bis(chloranyl)pyridin-2-yl]oxyaniline, CALCIUM ION, ... 著者 Sijbesma, E, Leysen, S, Ottmann, C. 登録日 2017-02-14 公開日 2017-07-19 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.37 Å) 主引用文献 Identification of Two Secondary Ligand Binding Sites in 14-3-3 Proteins Using Fragment Screening. Biochemistry, 56, 2017
5GLW	Tl-gal with LacNAc 分子名称: beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, galectin 著者 Jang, S.B, Hwang, E.Y. 登録日 2016-07-12 公開日 2016-11-09 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural Basis for Carbohydrate Recognition and Anti-inflammatory Modulation by Gastrointestinal Nematode Parasite Toxascaris leonina Galectin J. Biol. Chem., 291, 2016
6JLF	Crystal structure of a bacterial Bestrophin homolog from Klebsiella pneumoniae D179A mutation - HR 分子名称: Bestrophin homolog, ZINC ION 著者 Kittredge, A, Chen, S, Yang, T. 登録日 2019-03-05 公開日 2019-11-13 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.548 Å) 主引用文献 Dual Ca2+-dependent gates in human Bestrophin1 underlie disease-causing mechanisms of gain-of-function mutations. Commun Biol, 2, 2019
6JEZ	Covalent labeling of rVDR-LBD by turn-on fluorescent probe mediated by conjugate addition and cyclization 分子名称: (1R,3R)-5-(2-((1R,3aS,7aR,E)-1-((R)-6-hydroxy-6-methylheptan-2-yl)-7a-methyloctahydro-4H-inden-4-ylidene)ethylidene)-2- methylenecyclohexane-1,3-diol, 7-(diethylamino)chromen-2-one, Mediator of RNA polymerase II transcription subunit 1, ... 著者 Kojima, H, Yamamoto, K, Itoh, T. 登録日 2019-02-07 公開日 2020-02-12 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Cyclization Reaction-Based Turn-on Probe for Covalent Labeling of Target Proteins. Cell Chem Biol, 27, 2020
6TOM	Crystal structure of human BCL6 BTB domain in complex with compound 1 分子名称: 1,2-ETHANEDIOL, 5-[[2-[(3~{S},5~{R})-4,4-bis(fluoranyl)-3,5-dimethyl-piperidin-1-yl]-5-chloranyl-pyrimidin-4-yl]amino]-1-methyl-3-(3-methyl-3-oxidanyl-butyl)benzimidazol-2-one, B-cell lymphoma 6 protein 著者 Rodrigues, M.J, Le Bihan, Y.-V, van Montfort, R.L.M. 登録日 2019-12-11 公開日 2020-04-22 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 AchievingIn VivoTarget Depletion through the Discovery and Optimization of Benzimidazolone BCL6 Degraders. J.Med.Chem., 63, 2020
5GMM	Crystal structure of human Carbonic anhydrase I in complex with polmacoxib 分子名称: 4-[3-(3-fluorophenyl)-5,5-dimethyl-4-oxidanylidene-furan-2-yl]benzenesulfonamide, Carbonic anhydrase 1, ZINC ION 著者 Kim, H.T, Hwang, K.Y. 登録日 2016-07-14 公開日 2017-05-24 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.003 Å) 主引用文献 Structural insight into the inhibition of carbonic anhydrase by the COX-2-selective inhibitor polmacoxib (CG100649). Biochem. Biophys. Res. Commun., 478, 2016
5H2H	A three dimensional movie of structural changes in bacteriorhodopsin: structure obtained 40 ns after photoexcitation 分子名称: 2,3-DI-PHYTANYL-GLYCEROL, Bacteriorhodopsin, DECANE, ... 著者 Royant, A, Nango, E, Nakane, T, Tanaka, T, Arima, T, Neutze, R, Iwata, S. 登録日 2016-10-15 公開日 2016-12-21 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 A three-dimensional movie of structural changes in bacteriorhodopsin Science, 354, 2016
5NCL	Crystal structure of the Cbk1-Mob2 kinase-coactivator complex with an SSD1 peptide 分子名称: CBK1 kinase activator protein MOB2, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Protein SSD1, ... 著者 Gogl, G, Remenyi, A, Parker, B, Weiss, E. 登録日 2017-03-06 公開日 2018-05-16 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Ndr/Lats Kinases Bind Specific Mob-Family Coactivators through a Conserved and Modular Interface. Biochemistry, 2020
6JHB	Crystal structure of NADPH and 4-hydroxyphenylpyruvic acid bound AerF from Microcystis aeruginosa 分子名称: 3-(4-HYDROXY-PHENYL)PYRUVIC ACID, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Short chain dehydrogenase family protein 著者 Qiu, X, Wei, Y, Zhu, W. 登録日 2019-02-17 公開日 2019-11-27 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Structural and functional investigation of AerF, a NADPH-dependent alkenal double bond reductase participating in the biosynthesis of Choi moiety of aeruginosin J.Struct.Biol., 2019
5GKY	Structure of RyR1 in a closed state (C1 conformer) 分子名称: Peptidyl-prolyl cis-trans isomerase FKBP1A, Ryanodine receptor 1, ZINC ION 著者 Bai, X.C, Yan, Z, Wu, J.P, Yan, N. 登録日 2016-07-07 公開日 2016-08-24 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 The Central domain of RyR1 is the transducer for long-range allosteric gating of channel opening Cell Res., 26, 2016
6T38	Pseudomonas aeruginosa RmlA in complex with allosteric inhibitor 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, BROMIDE ION, CHLORIDE ION, ... 著者 Alphey, M.S, Xiao, G, Westwood, J.N. 登録日 2019-10-10 公開日 2020-08-19 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Next generation Glucose-1-phosphate thymidylyltransferase (RmlA) inhibitors: An extended SAR study to direct future design. Bioorg.Med.Chem., 50, 2021
7BBD	Crystal structure of monoubiquitinated TRIM21 RING (Ub-RING) In complex with ubiquitin charged Ube2N (Ube2N~Ub) and Ube2V2 分子名称: Polyubiquitin-B,E3 ubiquitin-protein ligase TRIM21, Polyubiquitin-C, Ubiquitin-conjugating enzyme E2 N, ... 著者 Kiss, L, Neuhaus, D, James, L.C. 登録日 2020-12-17 公開日 2021-01-27 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 RING domains act as both substrate and enzyme in a catalytic arrangement to drive self-anchored ubiquitination. Nat Commun, 12, 2021
6T3Y	Improved High Resolution Structure of MHC Class II complex 分子名称: ACETATE ION, GLYCEROL, MHC class II alpha chain, ... 著者 Halabi, S, Moncrieffe, M.C, Kaufman, J. 登録日 2019-10-11 公開日 2020-11-25 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 The dominantly expressed class II molecule from a resistant MHC haplotype presents only a few Marek's disease virus peptides by using an unprecedented binding motif. Plos Biol., 19, 2021
5GRH	Crystal structure of the alpha gamma heterodimer of human IDH3 in complex with Mg(2+) 分子名称: Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, Isocitrate dehydrogenase [NAD] subunit gamma, ... 著者 Ma, T, Peng, Y. 登録日 2016-08-11 公開日 2017-02-15 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Molecular mechanism of the allosteric regulation of the alpha gamma heterodimer of human NAD-dependent isocitrate dehydrogenase. Sci Rep, 7, 2017
6HFO	Human Hsp90 co-chaperone TTC4 C-domain 分子名称: PHOSPHATE ION, Tetratricopeptide repeat protein 4 著者 Huber, E.M, Groll, M. 登録日 2018-08-21 公開日 2019-03-27 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 The Co-chaperone Cns1 and the Recruiter Protein Hgh1 Link Hsp90 to Translation Elongation via Chaperoning Elongation Factor 2. Mol.Cell, 74, 2019
5H3T	m7G cap bound to GEMIN5-WD 分子名称: 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, GLYCEROL, Gem-associated protein 5 著者 Bharath, S.R, Tang, X, Song, H. 登録日 2016-10-27 公開日 2016-12-28 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.571 Å) 主引用文献 Structural basis for specific recognition of pre-snRNA by Gemin5 Cell Res., 26, 2016
7BVY	Crystal structure of MreB 5 of Spiroplasma citri bound to AMPPNP 分子名称: Cell shape determining protein MreB, MAGNESIUM ION, PHOSPHATE ION, ... 著者 Pande, V, Gayathri, P. 登録日 2020-04-12 公開日 2020-10-14 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 MreB5 Is a Determinant of Rod-to-Helical Transition in the Cell-Wall-less Bacterium Spiroplasma. Curr.Biol., 30, 2020
7BXZ	Crystal structure of the aminoglycoside 6'-N-acetyltransferase from Enterococcus faecium 分子名称: Aminoglycoside 6'-N-acetyltransferase 著者 Kwon, S, Park, H.H. 登録日 2020-04-21 公開日 2020-08-12 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.502 Å) 主引用文献 Structural analysis of a novel substrate-free form of the aminoglycoside 6'-N-acetyltransferase from Enterococcus faecium. Acta Crystallogr.,Sect.F, 76, 2020

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