PDB: 45677 件ウェブページステータス検索Chemie searchBIRD

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5IU5	Lambda-[Ru(TAP)2(dppz)]2+ bound to d(TCGGCICCGA)2 分子名称: BARIUM ION, DNA (5'-D(*TP*CP*GP*GP*CP*IP*CP*CP*GP*A)-3'), Ru(tap)2(dppz) complex 著者 Hall, J.P, Cardin, C.J. 登録日 2016-03-17 公開日 2017-06-21 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Unexpected enhancement of sensitised photo-oxidation by a Ru(II) complex on replacement of guanine with inosine in DNA To Be Published
5JO0	Structure of Plasmodium falciparum DXR in complex with a beta-substituted fosmidomycin analogue, LC56 and manganese 分子名称: 1,2-ETHANEDIOL, 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic, ... 著者 Sooriyaarachchi, S, Bergfors, T, Jones, T.A, Mowbray, S.L. 登録日 2016-05-01 公開日 2016-08-24 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Targeting an Aromatic Hotspot in Plasmodium falciparum 1-Deoxy-d-xylulose-5-phosphate Reductoisomerase with beta-Arylpropyl Analogues of Fosmidomycin. Chemmedchem, 11, 2016
7SK0	TWIK1 in MSP1D1 lipid nanodisc at pH 7.4 分子名称: N-OCTANE, POTASSIUM ION, Potassium channel subfamily K member 1 著者 Turney, T.S, Brohawn, S.G. 登録日 2021-10-19 公開日 2021-11-24 最終更新日 2022-06-22 実験手法 ELECTRON MICROSCOPY (3.33 Å) 主引用文献 Structural Basis for pH-gating of the K + channel TWIK1 at the selectivity filter. Nat Commun, 13, 2022
7SK1	TWIK1 in MSP1E3D1 Lipid Nanodisc at pH 5.5 分子名称: N-OCTANE, POTASSIUM ION, Potassium channel subfamily K member 1, ... 著者 Turney, T.S, Brohawn, S.G. 登録日 2021-10-19 公開日 2021-11-24 最終更新日 2022-06-22 実験手法 ELECTRON MICROSCOPY (3.43 Å) 主引用文献 Structural Basis for pH-gating of the K + channel TWIK1 at the selectivity filter. Nat Commun, 13, 2022
6D87	Structure of the Bovine p85alpha BH domain, R262T mutant 分子名称: Phosphatidylinositol 3-kinase regulatory subunit alpha, SULFATE ION 著者 Moore, S.A, Marshall, J.D, Anderson, D.H. 登録日 2018-04-25 公開日 2018-05-23 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Patient-derived mutations within the N-terminal domains of p85 alpha impact PTEN or Rab5 binding and regulation. Sci Rep, 8, 2018
5IGS	Macrolide 2'-phosphotransferase type I - complex with guanosine and oleandomycin 分子名称: (3S,5R,6S,7R,8R,11R,12S,13R,14S,15S)-6-HYDROXY-5,7,8,11,13,15-HEXAMETHYL-4,10-DIOXO-14-{[3,4,6-TRIDEOXY-3-(DIMETHYLAMINO)-BETA-D-XYLO-HEXOPYRANOSYL]OXY}-1,9-DIOXASPIRO[2.13]HEXADEC-12-YL 2,6-DIDEOXY-3-O-METHYL-ALPHA-L-ARABINO-HEXOPYRANOSIDE, GUANOSINE, ISOPROPYL ALCOHOL, ... 著者 Berghuis, A.M, Fong, D.H. 登録日 2016-02-28 公開日 2017-04-26 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 Structural Basis for Kinase-Mediated Macrolide Antibiotic Resistance. Structure, 25, 2017
7SC2	CRYSTAL STRUCTURE OF THE N-DOMAIN OF CARDIAC MUSCLE TROPONIN C TETHERED TO THE SWITCH REGION OF CARDIAC MUSCLE TROPONIN I (TETRAGONAL FORM) 分子名称: CALCIUM ION, Troponin C, slow skeletal and cardiac muscles,Troponin I, ... 著者 Sack, J.S. 登録日 2021-09-27 公開日 2021-12-01 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.814 Å) 主引用文献 X-ray structure of a human cardiac muscle troponin C/troponin I chimera in two crystal forms. Acta Crystallogr.,Sect.F, 78, 2022
5II1	Crystal Structure of the fifth bromodomain of human polybromo (PB1) in complex with 1-methylisochromeno[3,4-c]pyrazol-5(3H)-one 分子名称: 1-methyl[2]benzopyrano[3,4-c]pyrazol-5(3H)-one, Protein polybromo-1 著者 Filippakopoulos, P, Picaud, S, Felletar, I, Myrianthopoulos, V, Mikros, E, von Delft, F, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2016-03-01 公開日 2016-06-29 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Discovery and Optimization of a Selective Ligand for the Switch/Sucrose Nonfermenting-Related Bromodomains of Polybromo Protein-1 by the Use of Virtual Screening and Hydration Analysis. J.Med.Chem., 59, 2016
6BWP	Crystal structure of Deoxy Hemoglobin in complex with beta Cys93 modifying agent, TD3 分子名称: 1H-1,2,3-triazole-5-thiol, Hemoglobin subunit alpha, Hemoglobin subunit beta, ... 著者 Musayev, F.N, Safo, R.M, Safo, M.K. 登録日 2017-12-15 公開日 2018-01-03 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 A Triazole Disulfide Compound Increases the Affinity of Hemoglobin for Oxygen and Reduces the Sickling of Human Sickle Cells. Mol. Pharm., 15, 2018
7SC3	CRYSTAL STRUCTURE OF THE N-DOMAIN OF CARDIAC MUSCLE TROPONIN C TETHERED TO THE SWITCH REGION OF CARDIAC MUSCLE TROPONIN I (ORTHORHOMBIC FORM) 分子名称: CALCIUM ION, Troponin C, slow skeletal and cardiac muscles,Troponin I, ... 著者 Sack, J.S. 登録日 2021-09-27 公開日 2021-12-01 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.229 Å) 主引用文献 X-ray structure of a human cardiac muscle troponin C/troponin I chimera in two crystal forms. Acta Crystallogr.,Sect.F, 78, 2022
7S0I	CRYSTAL STRUCTURE OF N1 NEURAMINIDASE FROM A/Michigan/45/2015(H1N1) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neuraminidase, ... 著者 Zhu, X, Wilson, I.A. 登録日 2021-08-30 公開日 2021-12-08 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.892 Å) 主引用文献 A Novel Recombinant Influenza Virus Neuraminidase Vaccine Candidate Stabilized by a Measles Virus Phosphoprotein Tetramerization Domain Provides Robust Protection from Virus Challenge in the Mouse Model. Mbio, 12, 2021
2NNU	Crystal Structure of the Papillomavirus DNA Tethering Complex E2:Brd4 分子名称: Bromodomain-containing protein 4, Regulatory protein E2 著者 Abbate, E.A, Voitenleitner, C, Botchan, M.R. 登録日 2006-10-24 公開日 2007-01-09 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 Structure of the Papillomavirus DNA-Tethering Complex E2:Brd4 and a Peptide that Ablates HPV Chromosomal Association. Mol.Cell, 24, 2006
5IR6	The structure of bd oxidase from Geobacillus thermodenitrificans 分子名称: Bd-type quinol oxidase subunit I, Bd-type quinol oxidase subunit II, CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE, ... 著者 Safarian, S, Mueller, H, Rajendran, C, Preu, J, Ovchinnikov, S, Kusumoto, T, Hirose, T, Langer, J, Sakamoto, J, Michel, H. 登録日 2016-03-12 公開日 2016-05-04 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 Structure of a bd oxidase indicates similar mechanisms for membrane-integrated oxygen reductases. Science, 352, 2016
7SL9	CryoEM structure of SMCT1 分子名称: Sodium-coupled monocarboxylate transporter 1, butanoic acid, nanobody Nb2 著者 Qu, Q, Han, L, Panova, O, Feng, L, Skiniotis, G. 登録日 2021-10-23 公開日 2021-12-15 最終更新日 2022-01-26 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structure and mechanism of the SGLT family of glucose transporters. Nature, 601, 2022
5IOR	Flavin-dependent thymidylate synthase in complex with FAD and 2'-deoxyuridine-5'-monosulfate 分子名称: 2'-deoxy-5'-O-sulfouridine, FLAVIN-ADENINE DINUCLEOTIDE, RIBOFLAVIN, ... 著者 Bernard, S.M, Stull, F.W, Smith, J.L. 登録日 2016-03-08 公開日 2016-06-08 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Deprotonations in the Reaction of Flavin-Dependent Thymidylate Synthase. Biochemistry, 55, 2016
5ISL	Linked KDM5A Jmj Domain Bound to the Inhibitor C49 (2-{[(2-{[(E)-2-(dimethylamino)ethenyl](ethyl)amino}-2-oxoethyl)amino]methyl}pyridine-4-carboxylic acid) 分子名称: 1,2-ETHANEDIOL, 2-{[(2-{[(E)-2-(dimethylamino)ethenyl](ethyl)amino}-2-oxoethyl)amino]methyl}pyridine-4-carboxylic acid, GLYCEROL, ... 著者 Horton, J.R, Cheng, X. 登録日 2016-03-15 公開日 2016-07-27 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.694 Å) 主引用文献 Structural Basis for KDM5A Histone Lysine Demethylase Inhibition by Diverse Compounds. Cell Chem Biol, 23, 2016
7CD6	mAPE1-recessed dsDNA product complex 分子名称: DNA (5'-D(*GP*CP*GP*TP*AP*AP*TP*AP*C)-3'), DNA-(apurinic or apyrimidinic site) endonuclease 著者 Liu, T.C, Hsiao, Y.Y. 登録日 2020-06-18 公開日 2021-01-13 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.701 Å) 主引用文献 APE1 distinguishes DNA substrates in exonucleolytic cleavage by induced space-filling. Nat Commun, 12, 2021
7CJ3	Crystal structure of the transmembrane domain of Salpingoeca rosetta rhodopsin phosphodiesterase 分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Phosphodiesterase, RETINAL 著者 Ikuta, T, Shihoya, W, Yamashita, K, Nureki, O. 登録日 2020-07-09 公開日 2020-11-25 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural insights into the mechanism of rhodopsin phosphodiesterase. Nat Commun, 11, 2020
5ITC	2.2-Angstrom in meso crystal structure of Haloquadratum Walsbyi Bacteriorhodopsin (HwBR) from Styrene Maleic Acid (SMA) Polymer Nanodiscs 分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Bacteriorhodopsin-I, ... 著者 Broecker, J, Eger, B.T, Ernst, O.P. 登録日 2016-03-16 公開日 2017-01-25 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.999 Å) 主引用文献 Crystallogenesis of Membrane Proteins Mediated by Polymer-Bounded Lipid Nanodiscs. Structure, 25, 2017
7RTG	Crystal Structure of the Human Adenosine Deaminase 1 分子名称: Adenosine deaminase, ZINC ION 著者 Ma, M.T, Lieberman, R.L, Blazeck, J, Jennings, M.R. 登録日 2021-08-13 公開日 2022-01-12 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.591 Å) 主引用文献 Catalytically active holo Homo sapiens adenosine deaminase I adopts a closed conformation. Acta Crystallogr D Struct Biol, 78, 2022
5J4P	DIY G-Quadruplexes: Solution structure of d(GGTTTGGTTTTGGTTTGG) in sodium 分子名称: DNA (5'-D(*GP*GP*TP*TP*TP*GP*GP*TP*TP*TP*TP*GP*GP*TP*TP*TP*GP*G)-3') 著者 Dvorkin, S.A, Webba da Silva, M. 登録日 2016-04-01 公開日 2017-06-14 最終更新日 2024-06-19 実験手法 SOLUTION NMR 主引用文献 Encoding canonical DNA quadruplex structure. Sci Adv, 4, 2018
5J4W	DIY G-Quadruplexes: Solution structure of d(GGTTTGGTTTTGGTTGG) in sodium 分子名称: DNA (5'-D(*GP*GP*TP*TP*TP*GP*GP*TP*TP*TP*TP*GP*GP*TP*TP*GP*G)-3') 著者 Dvorkin, S.A, Webba da Silva, M. 登録日 2016-04-01 公開日 2017-04-12 最終更新日 2024-06-19 実験手法 SOLUTION NMR 主引用文献 Encoding canonical DNA quadruplex structure. Sci Adv, 4, 2018
2NY4	HIV-1 gp120 Envelope Glycoprotein (K231C, T257S, E268C, S334A, S375W) Complexed with CD4 and Antibody 17b 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY 17B, HEAVY CHAIN, ... 著者 Zhou, T, Xu, L, Dey, B, Hessell, A.J, Van Ryk, D, Xiang, S.H, Yang, X, Zhang, M.Y, Zwick, M.B, Arthos, J, Burton, D.R, Dimitrov, D.S, Sodroski, J, Wyatt, R, Nabel, G.J, Kwong, P.D. 登録日 2006-11-20 公開日 2007-02-06 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural definition of a conserved neutralization epitope on HIV-1 gp120. Nature, 445, 2007
5FLH	Free state of Ni-quercetinase 分子名称: DIMETHYL SULFOXIDE, NICKEL (II) ION, NITRATE ION, ... 著者 Jeoung, J.-H, Nianios, D, Fetzner, S, Dobbek, H. 登録日 2015-10-26 公開日 2016-06-01 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.802 Å) 主引用文献 Quercetin 2,4-Dioxygenase Activates Dioxygen in a Side-on O2 -Ni Complex. Angew.Chem.Int.Ed.Engl., 55, 2016
2O1C	Structure of the E. coli dihydroneopterin triphosphate pyrophosphohydrolase 分子名称: PYROPHOSPHATE, SULFATE ION, dATP pyrophosphohydrolase 著者 Gabelli, S.B, Bianchet, M.A, Amzel, L.M. 登録日 2006-11-28 公開日 2007-08-28 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure and function of the E. coli dihydroneopterin triphosphate pyrophosphatase: a Nudix enzyme involved in folate biosynthesis. Structure, 15, 2007

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