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2HZ9
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Crystal structure of Lys12Val/Asn95Val/Cys117Val mutant of human acidic fibroblast growth factor at 1.70 angstrom resolution.
分子名称: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
著者Dubey, V.K, Lee, J, Somasundaram, T, Blaber, M.
登録日2006-08-08
公開日2007-06-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Spackling the Crack: Stabilizing Human Fibroblast Growth Factor-1 by Targeting the N and C terminus beta-Strand Interactions
J.Mol.Biol., 371, 2007
2HZA
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BU of 2hza by Molmil
Nickel-bound full-length Escherichia coli NikR
分子名称: 3-CYCLOHEXYLPROPYL 4-O-ALPHA-D-GLUCOPYRANOSYL-BETA-D-GLUCOPYRANOSIDE, NICKEL (II) ION, Nickel-responsive regulator
著者Schreiter, E.R, Drennan, C.L.
登録日2006-08-08
公開日2006-08-22
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献NikR-operator complex structure and the mechanism of repressor activation by metal ions.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2HZB
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X-Ray Crystal Structure of Protein BH3568 from Bacillus halodurans. Northeast Structural Genomics Consortium BhR60.
分子名称: Hypothetical UPF0052 protein BH3568
著者Kuzin, A.P, Chen, Y, Seetharaman, J, Benach, J, Shastry, R, Conover, K, Ma, L.C, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
登録日2006-08-08
公開日2006-08-22
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献X-Ray structure of the hypothetical UPF0052 protein BH3568 from Bacillus halodurans. Northeast Structural Genomics Consortium BhR60.
To be Published
2HZC
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Crystal structure of the N-terminal RRM of the U2AF large subunit
分子名称: HEXAETHYLENE GLYCOL, Splicing factor U2AF 65 kDa subunit, ZINC ION
著者Thickman, K.R, Sickmier, E.A, Kielkopf, C.L.
登録日2006-08-08
公開日2006-08-29
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Alternative Conformations at the RNA-binding Surface of the N-terminal U2AF(65) RNA Recognition Motif.
J.Mol.Biol., 366, 2007
2HZD
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BU of 2hzd by Molmil
NMR structure of the DNA-binding TEA domain and insights into TEF-1 function
分子名称: Transcriptional enhancer factor TEF-1
著者Anbanandam, A, Veeraraghavan, S.
登録日2006-08-08
公開日2006-10-24
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Insights into transcription enhancer factor 1 (TEF-1) activity from the solution structure of the TEA domain.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2HZE
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BU of 2hze by Molmil
Crystal structures of a poxviral glutaredoxin in the oxidized and reduced states show redox-correlated structural changes
分子名称: Glutaredoxin-1
著者Bacik, J.P, Hazes, B.
登録日2006-08-08
公開日2006-11-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structures of a Poxviral Glutaredoxin in the Oxidized and Reduced States Show Redox-correlated Structural Changes.
J.Mol.Biol., 365, 2007
2HZF
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Crystal structures of a poxviral glutaredoxin in the oxidized and reduced states show redox-correlated structural changes
分子名称: Glutaredoxin-1
著者Bacik, J.P, Hazes, B.
登録日2006-08-08
公開日2006-11-21
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structures of a Poxviral Glutaredoxin in the Oxidized and Reduced States Show Redox-correlated Structural Changes.
J.Mol.Biol., 365, 2007
2HZG
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Crystal structure of predicted Mandelate racemase from Rhodobacter sphaeroides
分子名称: GLYCEROL, Mandelate racemase/muconate lactonizing enzyme/Enolase superfamily, SODIUM ION
著者Ramagopal, U.A, Toro, R, Almo, S.C, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2006-08-08
公開日2006-08-29
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Crystal structure of predicted Mandelate racemase from Rhodobacter sphaeroides
To be Published
2HZH
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Crystal structure of laccase from Coriolus zonatus at 2.6 A resolution
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, COPPER (II) ION, ...
著者Lyashenko, A.V, Mikhailov, A.M.
登録日2006-08-09
公開日2007-08-14
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of laccase from Coriolus zonatus at 2.6 A resolution
To be published
2HZI
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Abl kinase domain in complex with PD180970
分子名称: 6-(2,6-DICHLOROPHENYL)-2-[(4-FLUORO-3-METHYLPHENYL)AMINO]-8-METHYLPYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE, Proto-oncogene tyrosine-protein kinase ABL1
著者Cowan-Jacob, S.W, Fendrich, G, Liebetanz, J, Fabbro, D, Manley, P.
登録日2006-08-09
公開日2007-01-16
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural biology contributions to the discovery of drugs to treat chronic myelogenous leukaemia.
ACTA CRYSTALLOGR.,SECT.D, 63, 2007
2HZK
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BU of 2hzk by Molmil
Crystal structures of a sodium-alpha-keto acid binding subunit from a TRAP transporter in its open form
分子名称: GLYCEROL, TRAP-T family sorbitol/mannitol transporter, periplasmic binding protein, ...
著者Gonin, S, Arnoux, P, Pierru, B, Alonso, B, Sabaty, M, Pignol, D.
登録日2006-08-09
公開日2007-04-03
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structures of an Extracytoplasmic Solute Receptor from a TRAP transporter in its open and closed forms reveal a helix-swapped dimer requiring a cation for alpha-keto acid binding.
Bmc Struct.Biol., 7, 2007
2HZL
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BU of 2hzl by Molmil
Crystal structures of a sodium-alpha-keto acid binding subunit from a TRAP transporter in its closed forms
分子名称: PYRUVIC ACID, SODIUM ION, TRAP-T family sorbitol/mannitol transporter, ...
著者Gonin, S, Arnoux, P, Pierru, B, Alonso, B, Sabaty, M, Pignol, D.
登録日2006-08-09
公開日2007-04-03
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystal structures of an Extracytoplasmic Solute Receptor from a TRAP transporter in its open and closed forms reveal a helix-swapped dimer requiring a cation for alpha-keto acid binding.
Bmc Struct.Biol., 7, 2007
2HZM
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BU of 2hzm by Molmil
Structure of the Mediator head subcomplex Med18/20
分子名称: PHOSPHATE ION, RNA polymerase II mediator complex subunit 18, RNA polymerase II mediator complex subunit 20
著者Lariviere, L, Geiger, S, Hoeppner, S, Rother, S, Straesser, K, Cramer, P.
登録日2006-08-09
公開日2006-09-12
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure and TBP binding of the Mediator head subcomplex Med8-Med18-Med20.
Nat.Struct.Mol.Biol., 13, 2006
2HZN
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BU of 2hzn by Molmil
Abl kinase domain in complex with NVP-AFG210
分子名称: 1-[4-(PYRIDIN-4-YLOXY)PHENYL]-3-[3-(TRIFLUOROMETHYL)PHENYL]UREA, Proto-oncogene tyrosine-protein kinase ABL1
著者Cowan-Jacob, S.W, Fendrich, G, Liebetanz, J, Fabbro, D, Manley, P.
登録日2006-08-09
公開日2007-01-16
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural biology contributions to the discovery of drugs to treat chronic myelogenous leukaemia.
ACTA CRYSTALLOGR.,SECT.D, 63, 2007
2HZP
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BU of 2hzp by Molmil
Crystal Structure of Homo Sapiens Kynureninase
分子名称: Kynureninase, PYRIDOXAL-5'-PHOSPHATE
著者Lima, S, Khristoforov, R, Momany, C, Phillips, R.S.
登録日2006-08-09
公開日2006-11-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of Homo sapiens Kynureninase.
Biochemistry, 46, 2007
2HZQ
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Crystal structure of human apolipoprotein D (ApoD) in complex with progesterone
分子名称: Apolipoprotein D, PROGESTERONE
著者Eichinger, A, Skerra, A.
登録日2006-08-09
公開日2007-08-14
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural insight into the dual ligand specificity and mode of high density lipoprotein association of apolipoprotein d.
J.Biol.Chem., 282, 2007
2HZR
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Crystal structure of human apolipoprotein D (ApoD)
分子名称: Apolipoprotein D
著者Eichinger, A, Skerra, A.
登録日2006-08-09
公開日2007-08-14
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural insight into the dual ligand specificity and mode of high density lipoprotein association of apolipoprotein d.
J.Biol.Chem., 282, 2007
2HZS
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Structure of the Mediator head submodule Med8C/18/20
分子名称: RNA polymerase II mediator complex subunit 18, RNA polymerase II mediator complex subunit 20, RNA polymerase II mediator complex subunit 8
著者Lariviere, L, Geiger, S, Hoeppner, S, Rother, S, Straesser, K, Cramer, P.
登録日2006-08-09
公開日2006-09-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure and TBP binding of the Mediator head subcomplex Med8-Med18-Med20.
Nat.Struct.Mol.Biol., 13, 2006
2HZT
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Crystal Structure of a putative HTH-type transcriptional regulator ytcD
分子名称: Putative HTH-type transcriptional regulator ytcD
著者Madegowda, M, Eswaramoorthy, S, Desigan, K, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2006-08-09
公開日2006-08-29
最終更新日2021-02-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of a putative HTH-type transcription regulator ytcD
To be Published
2HZV
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NikR-operator DNA complex
分子名称: 5'-D(*AP*GP*TP*AP*TP*GP*AP*CP*GP*AP*AP*TP*AP*CP*TP*TP*AP*AP*AP*AP*TP*CP*GP*TP*CP*AP*TP*AP*CP*T)-3', 5'-D(*AP*GP*TP*AP*TP*GP*AP*CP*GP*AP*TP*TP*TP*TP*AP*AP*GP*TP*AP*TP*TP*CP*GP*TP*CP*AP*TP*AP*CP*T)-3', NICKEL (II) ION, ...
著者Schreiter, E.R, Drennan, C.L.
登録日2006-08-09
公開日2006-08-22
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献NikR-operator complex structure and the mechanism of repressor activation by metal ions.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2HZY
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Mouse fumarylacetoacetate hydrolase complexes with a transition-state mimic of the complete substrate
分子名称: 4-(2-CARBOXYETHYL)(HYDROXY)PHOSPHORYL]-3-OXOBUTANOIC ACID, CALCIUM ION, Fumarylacetoacetase, ...
著者Hurley, T.D, Timm, D.E.
登録日2006-08-09
公開日2006-08-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Slow-onset inhibition of fumarylacetoacetate hydrolase by phosphinate mimics of the tetrahedral intermediate: kinetics, crystal structure and pharmacokinetics.
Biochem.J., 402, 2007
2I00
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Crystal structure of acetyltransferase (GNAT family) from Enterococcus faecalis
分子名称: Acetyltransferase, GNAT family
著者Zhang, R, Zhou, M, Moy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2006-08-09
公開日2006-09-19
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The crystal structure of the acetyltransferase (GNAT family) from Enterococcus faecalis
To be Published, 2006
2I02
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CRYSTAL STRUCTURE OF a pyridoxamine 5'-phosphate oxidase-like family protein (NPUN_R6570) FROM NOSTOC PUNCTIFORME PCC 73102 AT 1.80 A RESOLUTION
分子名称: 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, CHLORIDE ION, FLAVIN MONONUCLEOTIDE, ...
著者Joint Center for Structural Genomics (JCSG)
登録日2006-08-09
公開日2006-08-29
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of general stress protein of COG3871 (ZP_00108720.1) from Nostoc punctiforme PCC 73102 at 1.80 A resolution
To be published
2I03
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Crystal structure of human dipeptidyl peptidase 4 (DPP IV) with potent alkynyl cyanopyrrolidine (ABT-279)
分子名称: 2-[4-({2-[(2S,5R)-2-(AMINOMETHYL)-5-ETHYNYLPYRROLIDIN-1-YL]-2-OXOETHYL}AMINO)-4-METHYLPIPERIDIN-1-YL]ISONICOTINIC ACID, Dipeptidyl peptidase 4
著者Longenecker, K.L, Madar, D.J.
登録日2006-08-09
公開日2006-12-12
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Discovery of 2-[4-{{2-(2S,5R)-2-cyano-5-ethynyl-1-pyrrolidinyl]-2-oxoethyl]amino]- 4-methyl-1-piperidinyl]-4-pyridinecarboxylic acid (ABT-279): a very potent, selective, effective, and well-tolerated inhibitor of dipeptidyl peptidase-IV, useful for the treatment of diabetes.
J.Med.Chem., 49, 2006
2I04
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X-ray crystal structure of MAGI-1 PDZ1 bound to the C-terminal peptide of HPV18 E6
分子名称: Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1, SULFATE ION, ...
著者Chen, X.S, Zhang, Y, Dasgupta, J, Banks, L, Thomas, M.
登録日2006-08-09
公開日2007-02-20
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structures of a Human Papillomavirus (HPV) E6 Polypeptide Bound to MAGUK Proteins: Mechanisms of Targeting Tumor Suppressors by a High-Risk HPV Oncoprotein.
J.Virol., 81, 2007

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