PDB: 45817 件ウェブページステータス検索Chemie searchBIRD

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6CVR	Human Aprataxin (Aptx) S242N bound to RNA-DNA, AMP and Zn product complex 分子名称: ADENOSINE MONOPHOSPHATE, Aprataxin, DNA (5'-D(*GP*AP*AP*TP*CP*AP*TP*AP*AP*C)-3'), ... 著者 Schellenberg, M.J, Tumbale, P.S, Williams, R.S. 登録日 2018-03-28 公開日 2018-07-04 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Mechanism of APTX nicked DNA sensing and pleiotropic inactivation in neurodegenerative disease. EMBO J., 37, 2018
5NFV	Crystal structure of catalytically inactive FnCas12 mutant bound to an R-loop structure containing a pre-crRNA mimic and full-length DNA target 分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CRISPR-associated endonuclease Cpf1, DNA non-target strand, ... 著者 Swarts, D.C, van der Oost, J, Jinek, M. 登録日 2017-03-16 公開日 2017-06-14 実験手法 X-RAY DIFFRACTION (2.501 Å) 主引用文献 Structural Basis for Guide RNA Processing and Seed-Dependent DNA Targeting by CRISPR-Cas12a. Mol. Cell, 66, 2017
6C1A	MBD2 in complex with methylated DNA 分子名称: Methyl-CpG-binding domain protein 2, UNKNOWN ATOM OR ION, complement to dna strand 1, ... 著者 Liu, K, Xu, C, Tempel, W, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) 登録日 2018-01-04 公開日 2018-02-14 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structural basis for the ability of MBD domains to bind methyl-CG and TG sites in DNA. J. Biol. Chem., 293, 2018
7ATG	Crystal structure of Z-DNA in complex with putrescinium and potassium cations at ultrahigh-resolution 分子名称: 4-azaniumylbutylazanium, DNA (5'-D(*CP*GP*CP*GP*CP*G)-3'), POTASSIUM ION 著者 Drozdzal, P, Gilski, M, Jaskolski, M. 登録日 2020-10-30 公開日 2021-08-11 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (0.6 Å) 主引用文献 Crystal structure of Z-DNA in complex with the polyamine putrescine and potassium cations at ultra-high resolution. Acta Crystallogr.,Sect.B, 77, 2021
3QNO	RB69 DNA Polymerase (Y567A) Ternary Complex with dATP Opposite 3tCo 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA Polymerase, ... 著者 Xia, S, Wang, M, Wang, J, Konigsberg, W.H. 登録日 2011-02-08 公開日 2012-03-14 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Using a Fluorescent Cytosine Analogue tC(o) To Probe the Effect of the Y567 to Ala Substitution on the Preinsertion Steps of dNMP Incorporation by RB69 DNA Polymerase. Biochemistry, 51, 2012
5HT2	Mouse Tdp2 reaction product (5'-phosphorylated DNA)-Mg2+ complex with 1-N6-etheno-adenine 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, DNA, ... 著者 Schellenberg, M.J, Vilas, C.K, Williams, R.S. 登録日 2016-01-26 公開日 2016-04-27 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.43 Å) 主引用文献 Reversal of DNA damage induced Topoisomerase 2 DNA-protein crosslinks by Tdp2. Nucleic Acids Res., 44, 2016
5ZKJ	Human EXOG-H140A in complex with RNA/DNA hybrid duplex 分子名称: CHLORIDE ION, DNA (5'-D(*CP*GP*TP*GP*AP*CP*AP*TP*CP*CP*CP*G)-3'), MAGNESIUM ION, ... 著者 Wu, C.C, Lin, J.L.J, Yuan, H.S. 登録日 2018-03-24 公開日 2019-04-03 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.798 Å) 主引用文献 A unique exonuclease ExoG cleaves between RNA and DNA in mitochondrial DNA replication. Nucleic Acids Res., 47, 2019
6CVT	Human Aprataxin (Aptx) V263G bound to RNA-DNA, AMP and Zn product complex 分子名称: ADENOSINE MONOPHOSPHATE, Aprataxin, DNA (5'-D(*GP*AP*AP*TP*CP*AP*TP*AP*AP*C)-3'), ... 著者 Schellenberg, M.J, Tumbale, P.S, Williams, R.S. 登録日 2018-03-28 公開日 2018-07-04 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.941 Å) 主引用文献 Mechanism of APTX nicked DNA sensing and pleiotropic inactivation in neurodegenerative disease. EMBO J., 37, 2018
8F42	Engineering Crystals with Tunable Symmetries from 14- or 16-Base-Long DNA Strands 分子名称: 2'-(4-ETHOXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE, DNA (5'-D(*CP*GP*CP*TP*TP*AP*AP*GP*GP*AP*AP*TP*TP*CP*GP*C)-3') 著者 Zhang, C, Zhao, J, Lu, B, Sha, R, Seeman, N.C, Noinaj, N, Mao, C. 登録日 2022-11-10 公開日 2023-03-08 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Engineering DNA Crystals toward Studying DNA-Guest Molecule Interactions. J.Am.Chem.Soc., 145, 2023
6CVO	Human Aprataxin (Aptx) bound to nicked RNA-DNA, AMP and Zn product complex 分子名称: ADENOSINE MONOPHOSPHATE, Aprataxin, BETA-MERCAPTOETHANOL, ... 著者 Schellenberg, M.J, Tumbale, P.P, Williams, R.S. 登録日 2018-03-28 公開日 2018-08-29 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Mechanism of APTX nicked DNA sensing and pleiotropic inactivation in neurodegenerative disease. EMBO J., 37, 2018
3RRG	Ternary Structure of the large fragment of Taq DNA polymerase bound to an abasic site and a ddGTP 分子名称: (5'-D(*AP*AP*AP*(3DR)P*CP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DDG))-3'), 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, ... 著者 Marx, A, Diederichs, K, Obeid, S. 登録日 2011-04-29 公開日 2012-02-15 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Amino Acid templating mechanisms in selection of nucleotides opposite abasic sites by a family a DNA polymerase. J.Biol.Chem., 287, 2012
1D39	COVALENT MODIFICATION OF GUANINE BASES IN DOUBLE STRANDED DNA: THE 1.2 ANGSTROMS Z-DNA STRUCTURE OF D(CGCGCG) IN THE PRESENCE OF CUCL2 分子名称: COPPER (II) ION, DNA (5'-D(*CP*(CU)GP*CP*(CU)GP*CP*(CU)G)-3'), SODIUM ION 著者 Kagawa, T.F, Geierstanger, B.H, Wang, A.H.-J, Ho, P.S. 登録日 1991-05-07 公開日 1992-04-15 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Covalent modification of guanine bases in double-stranded DNA. The 1.2-A Z-DNA structure of d(CGCGCG) in the presence of CuCl2. J.Biol.Chem., 266, 1991
7LAS	Cryo-EM structure of PCV2 Replicase bound to ssDNA 分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent helicase Rep, DNA (5'-D(P*GP*AP*TP*CP*GP*AP*TP*CP*GP*A)-3'), ... 著者 Khayat, R. 登録日 2021-01-06 公開日 2021-08-25 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 Mechanism of DNA Interaction and Translocation by the Replicase of a Circular Rep-Encoding Single-Stranded DNA Virus. Mbio, 12, 2021
7LAR	Cryo-EM structure of PCV2 Replicase bound to ssDNA 分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent helicase Rep, DNA (5'-D(P*TP*TP*TP*TP*TP*T)-3'), ... 著者 Khayat, R. 登録日 2021-01-06 公開日 2021-08-25 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Mechanism of DNA Interaction and Translocation by the Replicase of a Circular Rep-Encoding Single-Stranded DNA Virus. Mbio, 12, 2021
8UZT	Mitochondrial single-stranded binding protein bound to DNA 分子名称: GLYCEROL, SODIUM ION, Single-stranded DNA-binding protein, ... 著者 Riccio, A.A, Pedersen, L.C, Bouvette, J, Borgnia, J.M, Copeland, W.C. 登録日 2023-11-16 公開日 2024-08-21 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structures of the mitochondrial single-stranded DNA binding protein with DNA and DNA polymerase gamma. Nucleic Acids Res., 2024
7RCU	Synthetic Max homodimer mimic in complex with DNA 分子名称: 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, 2-(2,5-dioxopyrrolidin-1-yl)acetamide, ACETAMIDE, ... 著者 Speltz, T, Qiao, Z, Shangguan, S, Fanning, S, Greene, J, Moellering, R. 登録日 2021-07-08 公開日 2022-09-14 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.69 Å) 主引用文献 Targeting MYC with modular synthetic transcriptional repressors derived from bHLH DNA-binding domains. Nat.Biotechnol., 41, 2023
3QEP	RB69 DNA Polymerase (L561A/S565G/Y567A) Ternary Complex with dTTP Opposite Difluorotoluene Nucleoside 分子名称: CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), DNA (5'-D(*TP*CP*GP*(DFT)P*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3'), ... 著者 Xia, S, Konigsberg, W.H, Wang, J. 登録日 2011-01-20 公開日 2011-08-31 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Hydrogen-bonding capability of a templating difluorotoluene nucleotide residue in an RB69 DNA polymerase ternary complex. J.Am.Chem.Soc., 133, 2011
3RRH	Ternary Structure of the large fragment of Taq DNA polymerase bound to an abasic site and a ddTTP 分子名称: (5'-D(*AP*AP*AP*(3DR)P*AP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(2DT))-3'), ACETATE ION, ... 著者 Marx, A, Diederichs, K, Obeid, S. 登録日 2011-04-29 公開日 2012-02-15 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Amino Acid templating mechanisms in selection of nucleotides opposite abasic sites by a family a DNA polymerase. J.Biol.Chem., 287, 2012
8XVB	Cryo-EM structure of ATP-DNA-MuB filaments 分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent target DNA activator B, DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), ... 著者 Zhao, X, Zhang, K, Li, S. 登録日 2024-01-14 公開日 2024-08-14 最終更新日 2024-08-21 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Elucidating the Architectural dynamics of MuB filaments in bacteriophage Mu DNA transposition Nat Commun, 15, 2024
6C1V	MBD2 in complex with double-stranded DNA 分子名称: 12-mer DNA, Methyl-CpG-binding domain protein 2, UNKNOWN ATOM OR ION 著者 Lei, M, Tempel, W, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) 登録日 2018-01-05 公開日 2018-02-14 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis for the ability of MBD domains to bind methyl-CG and TG sites in DNA. J. Biol. Chem., 293, 2018
5ZKI	Human EXOG-H140A in complex with duplex DNA 分子名称: CHLORIDE ION, DNA (5'-D(*CP*GP*GP*GP*AP*TP*AP*TP*CP*CP*CP*G)-3'), MAGNESIUM ION, ... 著者 Wu, C.C, Lin, J.L.J, Yuan, H.S. 登録日 2018-03-24 公開日 2019-04-03 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.321 Å) 主引用文献 A unique exonuclease ExoG cleaves between RNA and DNA in mitochondrial DNA replication. Nucleic Acids Res., 47, 2019
3RR7	Binary Structure of the large fragment of Taq DNA polymerase bound to an abasic site 分子名称: (5'-D(*AP*AP*AP*(3DR)P*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3'), DNA polymerase I, ... 著者 Marx, A, Diederichs, K, Obeid, S. 登録日 2011-04-29 公開日 2012-02-15 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Amino Acid templating mechanisms in selection of nucleotides opposite abasic sites by a family a DNA polymerase. J.Biol.Chem., 287, 2012
3GV8	Human DNA polymerase iota in complex with T template DNA and incoming dGTP 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(*AP*GP*GP*AP*CP*CP*C)-3', 5'-D(*AP*TP*GP*GP*GP*TP*CP*CP*T)-3', ... 著者 Kirouac, K.N, Ling, H. 登録日 2009-03-30 公開日 2009-06-02 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis of error-prone replication and stalling at a thymine base by human DNA polymerase iota Embo J., 28, 2009
3QNN	RB69 DNA Polymerase (Y567A) Ternary Complex with dGT Opposite 3tCo 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA Primer, ... 著者 Xia, S, Wang, M, Wang, J, Konigsberg, W.H. 登録日 2011-02-08 公開日 2012-02-08 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Using a Fluorescent Cytosine Analogue tC(o) To Probe the Effect of the Y567 to Ala Substitution on the Preinsertion Steps of dNMP Incorporation by RB69 DNA Polymerase. Biochemistry, 51, 2012
5INN	Mouse Tdp2 D358N protein, apo state with increased disorder amongst variable DNA-binding grasp conformations 分子名称: CHLORIDE ION, GLYCEROL, SULFATE ION, ... 著者 Schellenberg, M.J, Appel, C.D, Williams, R.S. 登録日 2016-03-07 公開日 2016-04-27 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Reversal of DNA damage induced Topoisomerase 2 DNA-protein crosslinks by Tdp2. Nucleic Acids Res., 44, 2016

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