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8D3O
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Crystal structure of human Apoptosis-Inducing Factor (AIF) complexed with 8-methoxyquinolin-4-amine
分子名称: 1,2-ETHANEDIOL, 8-methoxyquinolin-4-amine, Apoptosis-inducing factor (AIF), ...
著者Brosey, C.A, Tainer, J.A.
登録日2022-06-01
公開日2023-11-08
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Chemical screening by time-resolved X-ray scattering to discover allosteric probes.
Nat.Chem.Biol., 2024
8D3J
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Crystal structure of human Apoptosis-Inducing Factor (AIF) complexed with 6-fluoro-2-methylquinolin-4-amine
分子名称: 1,2-ETHANEDIOL, 6-fluoro-2-methylquinolin-4-amine, Apoptosis-inducing factor 1, ...
著者Brosey, C.A, Tainer, J.A.
登録日2022-06-01
公開日2023-11-08
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Chemical screening by time-resolved X-ray scattering to discover allosteric probes.
Nat.Chem.Biol., 2024
8D3H
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Crystal structure of human Apoptosis-Inducing Factor (AIF) W196A mutant complexed with 7-chloroquinolin-4-amine
分子名称: 1,2-ETHANEDIOL, 7-chloroquinolin-4-amine, Apoptosis-inducing factor 1, ...
著者Brosey, C.A, Tainer, J.A.
登録日2022-06-01
公開日2023-11-08
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Chemical screening by time-resolved X-ray scattering to discover allosteric probes.
Nat.Chem.Biol., 2024
8D3E
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BU of 8d3e by Molmil
Crystal structure of human Apoptosis-Inducing Factor (AIF) W196A mutant complexed with 6-fluoroquinolin-4-amine
分子名称: 1,2-ETHANEDIOL, 6-fluoroquinolin-4-amine, Apoptosis-inducing factor 1, ...
著者Brosey, C.A, Tainer, J.A.
登録日2022-06-01
公開日2023-11-08
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Chemical screening by time-resolved X-ray scattering to discover allosteric probes.
Nat.Chem.Biol., 2024
8D3I
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Crystal structure of human Apoptosis-Inducing Factor (AIF) W196A mutant complexed with quinolin-4-amine
分子名称: 1,2-ETHANEDIOL, Apoptosis-inducing factor 1, mitochondrial, ...
著者Brosey, C.A, Tainer, J.A.
登録日2022-06-01
公開日2023-11-08
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Chemical screening by time-resolved X-ray scattering to discover allosteric probes.
Nat.Chem.Biol., 2024
8D3N
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BU of 8d3n by Molmil
Crystal structure of human Apoptosis-Inducing Factor (AIF) complexed with 7-chloroquinolin-4-amine
分子名称: 1,2-ETHANEDIOL, 7-chloroquinolin-4-amine, Apoptosis-inducing factor 1, ...
著者Brosey, C.A, Tainer, J.A.
登録日2022-06-01
公開日2023-11-08
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Chemical screening by time-resolved X-ray scattering to discover allosteric probes.
Nat.Chem.Biol., 2024
8D3K
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BU of 8d3k by Molmil
Crystal structure of human Apoptosis-Inducing Factor (AIF) complexed with 8-fluoro-2-methylquinolin-4-amine
分子名称: 1,2-ETHANEDIOL, 8-fluoro-2-methylquinolin-4-amine, Apoptosis-inducing factor 1, ...
著者Brosey, C.A, Tainer, J.A.
登録日2022-06-01
公開日2023-11-08
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Chemical screening by time-resolved X-ray scattering to discover allosteric probes.
Nat.Chem.Biol., 2024
7XY7
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Adenosine receptor bound to a non-selective agonist in complex with a G protein obtained by cryo-EM
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ...
著者Zhang, J.Y, Chen, Y, Hua, T, Song, G.J.
登録日2022-05-31
公開日2023-05-03
実験手法ELECTRON MICROSCOPY (3.26 Å)
主引用文献Cryo-EM structure of the human adenosine A 2B receptor-G s signaling complex.
Sci Adv, 8, 2022
7XY6
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Adenosine receptor bound to an agonist in complex with G protein obtained by cryo-EM
分子名称: 2-[6-azanyl-3,5-dicyano-4-[4-(cyclopropylmethoxy)phenyl]pyridin-2-yl]sulfanylethanamide, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Zhang, J.Y, Chen, Y, Hua, T, Song, G.J.
登録日2022-05-31
公開日2023-05-03
最終更新日2023-05-31
実験手法ELECTRON MICROSCOPY (2.99 Å)
主引用文献Cryo-EM structure of the human adenosine A 2B receptor-G s signaling complex.
Sci Adv, 8, 2022
8A12
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Plasmodium falciparum Myosin A full-length, post-rigor state complexed to Mg.ATP-gamma-S
分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Moussaoui, D, Robblee, J.P, Auguin, D, Fisher, F, Fagnant, P.M, MacFarlane, J.E, Mueller-Dieckmann, C, Baum, J, Robert-Paganin, J, Trybus, K.M, Houdusse, A.
登録日2022-05-31
公開日2023-06-21
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Mechanism of small molecule inhibition of Plasmodium falciparum myosin A informs antimalarial drug design.
Nat Commun, 14, 2023
8A16
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Human PTPRM domains FN3-4, in spacegroup P212121
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor-type tyrosine-protein phosphatase mu, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose
著者Caroe, E, Graham, S.C, Sharpe, H.J, Deane, J.E.
登録日2022-05-31
公開日2023-03-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献Determinants of receptor tyrosine phosphatase homophilic adhesion: Structural comparison of PTPRK and PTPRM extracellular domains.
J.Biol.Chem., 299, 2023
8A17
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Human PTPRM domains FN3-4, in spacegroup P3221
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor-type tyrosine-protein phosphatase mu, ...
著者Shamin, M, Graham, S.C, Sharpe, H.J, Deane, J.E.
登録日2022-05-31
公開日2023-03-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3.09 Å)
主引用文献Determinants of receptor tyrosine phosphatase homophilic adhesion: Structural comparison of PTPRK and PTPRM extracellular domains.
J.Biol.Chem., 299, 2023
7XXH
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BU of 7xxh by Molmil
Cryo-EM structure of the purinergic receptor P2Y1R in complex with 2MeSADP and G11
分子名称: 2-(methylsulfanyl)adenosine 5'-(trihydrogen diphosphate), Guanine nucleotide-binding protein G(11) subunit alpha, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Tan, Q, Li, B, Han, S, Zhao, Q, Wu, B.
登録日2022-05-30
公開日2023-06-07
最終更新日2023-09-20
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural insights into signal transduction of the purinergic receptors P2Y1R and P2Y12R.
Protein Cell, 14, 2023
7XXJ
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Echo 18 incubated with FcRn at pH5.5
分子名称: PALMITIC ACID, VP1, VP2, ...
著者Liu, C.C, Qu, X.
登録日2022-05-30
公開日2022-06-29
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.33 Å)
主引用文献Human FcRn Is a Two-in-One Attachment-Uncoating Receptor for Echovirus 18.
Mbio, 13, 2022
7XXG
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Echo 18 at pH5.5
分子名称: PALMITIC ACID, VP1, VP2, ...
著者Liu, C.C, Qu, X.
登録日2022-05-30
公開日2022-06-29
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.37 Å)
主引用文献Human FcRn Is a Two-in-One Attachment-Uncoating Receptor for Echovirus 18.
Mbio, 13, 2022
7XXI
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BU of 7xxi by Molmil
Cryo-EM structure of the purinergic receptor P2Y12R in complex with 2MeSADP and Gi
分子名称: 2-(methylsulfanyl)adenosine 5'-(trihydrogen diphosphate), Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Tan, Q, Li, B, Han, S, Zhao, Q, Wu, B.
登録日2022-05-30
公開日2023-06-07
最終更新日2023-09-20
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural insights into signal transduction of the purinergic receptors P2Y1R and P2Y12R.
Protein Cell, 14, 2023
8A0R
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BU of 8a0r by Molmil
Crystal structure of poplar glutathione transferase U20 in complex with pinocembrin
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, Glutathione transferase, ...
著者Didierjean, C, Favier, F.
登録日2022-05-30
公開日2022-07-20
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Biochemical and Structural Insights on the Poplar Tau Glutathione Transferase GSTU19 and 20 Paralogs Binding Flavonoids.
Front Mol Biosci, 9, 2022
8A0Q
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Crystal structure of poplar glutathione transferase U20 in complex with baicalein
分子名称: 5,6,7-trihydroxy-2-phenyl-4H-chromen-4-one, CHLORIDE ION, Glutathione transferase
著者Didierjean, C, Favier, F.
登録日2022-05-30
公開日2022-07-20
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.048 Å)
主引用文献Biochemical and Structural Insights on the Poplar Tau Glutathione Transferase GSTU19 and 20 Paralogs Binding Flavonoids.
Front Mol Biosci, 9, 2022
8A0P
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BU of 8a0p by Molmil
Crystal structure of poplar glutathione transferase U20 in complex with morin
分子名称: 2-[2,4-bis(oxidanyl)phenyl]-3,5,7-tris(oxidanyl)chromen-4-one, CHLORIDE ION, Glutathione transferase
著者Didierjean, C, Favier, F.
登録日2022-05-30
公開日2022-07-20
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.686 Å)
主引用文献Biochemical and Structural Insights on the Poplar Tau Glutathione Transferase GSTU19 and 20 Paralogs Binding Flavonoids.
Front Mol Biosci, 9, 2022
7XXA
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Complex of Echo 18 and FcRn at pH7.4
分子名称: IgG receptor FcRn large subunit p51, VP1, VP2, ...
著者Liu, C.C, Qu, X.
登録日2022-05-29
公開日2022-06-29
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.09 Å)
主引用文献Human FcRn Is a Two-in-One Attachment-Uncoating Receptor for Echovirus 18.
Mbio, 13, 2022
7XX9
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BU of 7xx9 by Molmil
Solution structure of RRM2 of Human SART3
分子名称: Squamous cell carcinoma antigen recognized by T-cells 3
著者Kim, I, Bang, K.M, Park, C, Kim, N.K, Suh, J.Y.
登録日2022-05-29
公開日2023-08-30
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution structure of RRM1 of Human SART3
To Be Published
7XX8
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Solution structure of RRM1 of Human SART3
分子名称: Squamous cell carcinoma antigen recognized by T-cells 3
著者Kim, I, Bang, K.M, Park, C, Kim, N.K, Suh, J.Y.
登録日2022-05-29
公開日2023-08-30
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution structure of RRM1 of Human SART3
To Be Published
8A0O
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Crystal structure of poplar glutathione transferase U20 in complex with galangin
分子名称: CHLORIDE ION, Glutathione transferase, galangin
著者Didierjean, C, Favier, F.
登録日2022-05-29
公開日2022-07-20
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.837 Å)
主引用文献Biochemical and Structural Insights on the Poplar Tau Glutathione Transferase GSTU19 and 20 Paralogs Binding Flavonoids.
Front Mol Biosci, 9, 2022
8A0L
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Tubulin-CW1-complex
分子名称: (3~{S},4~{R},8~{S},10~{S},12~{S},14~{S})-14-[(~{Z},4~{R})-4-(hydroxymethyl)hex-2-en-2-yl]-4,12-dimethoxy-9,9-dimethyl-3,8,10-tris(oxidanyl)-1-oxacyclotetradecan-2-one, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ...
著者Prota, A.E, Diaz, J.F, Steinmetz, M.O, Oliva, M.A.
登録日2022-05-28
公開日2022-12-14
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.9981 Å)
主引用文献Chemical modulation of microtubule structure through the laulimalide/peloruside site.
Structure, 31, 2023
7XX3
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Crystal structure of human Superoxide Dismutase (SOD1) in complex with a fungal metabolite molecule, Phialomustin B (PB)
分子名称: (2~{E},4~{E},6~{S})-4,6-dimethyldeca-2,4-dienoic acid, DIMETHYL SULFOXIDE, GLYCEROL, ...
著者Padmanabhan, B, Unni, S.
登録日2022-05-28
公開日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Phialomustin-B a fungal metabolite isolated from Phialophora mustea modulates Superoxide Dismutase 1 (SOD1) aggregation: Therapeutic potential in Amyotrophic lateral sclerosis (ALS)
To Be Published

222415

件を2024-07-10に公開中

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