8D3E

Crystal structure of human Apoptosis-Inducing Factor (AIF) W196A mutant complexed with 6-fluoroquinolin-4-amine

Summary for 8D3E

• Entry DOI: 10.2210/pdb8d3e/pdb
• Descriptor: Apoptosis-inducing factor 1, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE, 6-fluoroquinolin-4-amine, ... (6 entities in total)
• Functional Keywords: oxidoreductase, mitochondrial import, oxidative phosphorylation, saxs
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 120603.72

Authors

Brosey, C.A.,Tainer, J.A. (deposition date: 2022-06-01, release date: 2023-11-08)

• Primary citation: Brosey, C.A.,Link, T.,Shen, R.,Moiani, D.,Burnett, K.,Hura, G.,Jones, D.E.,Tainer, J.A.; Integrating early structural selection into chemical library screening for drug discovery with high-throughput small-angle X-ray scattering (SAXS); To Be Published,

Experimental method

X-RAY DIFFRACTION (2.38 Å)