PDB: 45118 件ウェブページステータス検索Chemie searchBIRD

---

7L0N	Circulating SARS-CoV-2 spike N439K variants maintain fitness while evading antibody-mediated immunity 分子名称: 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... 著者 Snell, G, Czudnochowski, N, Dillen, J, Nix, J.C, Croll, T.I, Corti, D. 登録日 2020-12-11 公開日 2021-02-17 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.78 Å) 主引用文献 Circulating SARS-CoV-2 spike N439K variants maintain fitness while evading antibody-mediated immunity. Cell, 184, 2021
3USI	Crystal structure of LeuT bound to L-leucine in space group P2 from lipid bicelles 分子名称: LEUCINE, SODIUM ION, Transporter 著者 Wang, H, Elferich, J, Gouaux, E. 登録日 2011-11-23 公開日 2012-01-11 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.106 Å) 主引用文献 Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context. Nat.Struct.Mol.Biol., 19, 2012
4A3U	X-structure of the old yellow enzyme homologue from zymomonas mobilis (NCR) 分子名称: ACETATE ION, FLAVIN MONONUCLEOTIDE, NADH:FLAVIN OXIDOREDUCTASE/NADH OXIDASE, ... 著者 Hoeffken, H.W. 登録日 2011-10-04 公開日 2012-10-17 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal Structure Determination and Mutagenesis Analysis of the Ene Reductase Ncr. Chembiochem, 13, 2012
4RT2	Ternary complex crystal structure of DNA polymerase Beta with (alpha,beta)-CH2-(beta,gamma)-NH-dTTP 分子名称: 2'-deoxy-5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonoamino)phosphoryl]methyl}phosphoryl]-3,4-dihydrothymidine, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... 著者 Batra, V.K, Wilson, S.H. 登録日 2014-11-12 公開日 2015-07-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Two Scaffolds from Two Flips: (alpha, beta)/(beta, gamma) CH2/NH "Met-Im" Analogues of dTTP. Org.Lett., 17, 2015
4RZM	Crystal structure of the Lsd19-lasalocid A complex 分子名称: CHLORIDE ION, Epoxide hydrolase LasB, FORMIC ACID, ... 著者 Mathews, I.I, Hotta, K, Chen, X, Kim, C.-Y. 登録日 2014-12-22 公開日 2015-01-21 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.33 Å) 主引用文献 Epoxide hydrolase-lasalocid a structure provides mechanistic insight into polyether natural product biosynthesis. J.Am.Chem.Soc., 137, 2015
7LQY	Structure of squirrel TRPV1 in apo state 分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoinositol, CHLORIDE ION, ... 著者 Nadezhdin, K.D, Neuberger, A, Sobolevsky, A.I. 登録日 2021-02-15 公開日 2021-04-21 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.19 Å) 主引用文献 Extracellular cap domain is an essential component of the TRPV1 gating mechanism. Nat Commun, 12, 2021
7LGT	HLA-B*07:02 in complex with 229E-derived coronavirus nucleocapsid peptide N75-83 分子名称: BROMIDE ION, Beta-2-microglobulin, CHLORIDE ION, ... 著者 Gras, S, Szeto, C, Chatzileontiadou, D.S.M. 登録日 2021-01-21 公開日 2021-04-21 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 CD8 + T cells specific for an immunodominant SARS-CoV-2 nucleocapsid epitope cross-react with selective seasonal coronaviruses. Immunity, 54, 2021
7LQZ	Structure of squirrel TRPV1 in complex with RTX 分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Osm-9-like TRP channel 1, SODIUM ION, ... 著者 Neuberger, A, Nadezhdin, K.D, Sobolevsky, A.I. 登録日 2021-02-15 公開日 2021-04-21 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.41 Å) 主引用文献 Extracellular cap domain is an essential component of the TRPV1 gating mechanism. Nat Commun, 12, 2021
5TYE	DNA Polymerase Mu Product Complex, 10 mM Mg2+ (60 min) 分子名称: 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... 著者 Jamsen, J.A, Wilson, S.H. 登録日 2016-11-19 公開日 2017-08-30 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.047 Å) 主引用文献 Time-lapse crystallography snapshots of a double-strand break repair polymerase in action. Nat Commun, 8, 2017
5U1Z	X-ray structure of the WlarG aminotransferase, apo form, from Campylobacter jejune 分子名称: CHLORIDE ION, Putative aminotransferase, SODIUM ION 著者 Holden, H.M, Thoden, J.B, Dow, G.T, Gilbert, M. 登録日 2016-11-29 公開日 2017-01-11 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural investigation on WlaRG from Campylobacter jejuni: A sugar aminotransferase. Protein Sci., 26, 2017
5U9J	Crystal structure of the FKBP domain of human aryl hydrocarbon receptor-interacting protein-like 1 (AIPL1) complexed with geranyl geranyl pyrophoshate 分子名称: Aryl hydrocarbon receptor-interacting protein-like 1 (AIPL1), GERAN-8-YL GERAN, ISOPROPYL ALCOHOL, ... 著者 Yadav, R.P, Gakhar, L, Liping, Y, Artemyev, N.O. 登録日 2016-12-16 公開日 2017-07-26 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Unique structural features of the AIPL1-FKBP domain that support prenyl lipid binding and underlie protein malfunction in blindness. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5UC6	Structural insights into IL-1 alpha recognition by a naphthyl-modified aptamer that mimics IL-1RI Domain III 分子名称: DNA (5'-D(*CP*G)-R(P*(85Y))-D(P*GP*AP*G)-R(P*(85Y)P*(85Y))-D(P*A)-R(P*(85Y))-D(P*GP*GP*G)-R(P*(85Y)P*(85Y))-D(P*AP*GP*AP*G)-R(P*(85Y))-D(P*CP*GP*(ATD))-3'), Interleukin-1 alpha, MAGNESIUM ION, ... 著者 Ren, X, Pyle, A. 登録日 2016-12-21 公開日 2017-10-11 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural basis for IL-1 alpha recognition by a modified DNA aptamer that specifically inhibits IL-1 alpha signaling. Nat Commun, 8, 2017
5UD2	Class II fructose-1,6-bisphosphate aldolase H180Q variant of Helicobacter pylori with DHAP 分子名称: 1,3-DIHYDROXYACETONEPHOSPHATE, Fructose-bisphosphate aldolase, SODIUM ION, ... 著者 Jacques, B, Sygusch, J. 登録日 2016-12-23 公開日 2018-04-11 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.775 Å) 主引用文献 Active site remodeling during the catalytic cycle in metal-dependent fructose-1,6-bisphosphate aldolases. J. Biol. Chem., 293, 2018
5UCZ	Class II fructose-1,6-bisphosphate aldolase E149A variant of Helicobacter pylori with DHAP 分子名称: 1,3-DIHYDROXYACETONEPHOSPHATE, Fructose-bisphosphate aldolase, SODIUM ION, ... 著者 Jacques, B, Sygusch, J. 登録日 2016-12-23 公開日 2018-04-11 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Active site remodeling during the catalytic cycle in metal-dependent fructose-1,6-bisphosphate aldolases. J. Biol. Chem., 293, 2018
5U20	X-ray structure of the WlaRG aminotransferase from Campylobacter jejuni, internal PLP-aldimine 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Putative aminotransferase, ... 著者 Thoden, J.B, Holden, H.M, Dow, G.T, Gilbert, M. 登録日 2016-11-29 公開日 2017-01-11 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural investigation on WlaRG from Campylobacter jejuni: A sugar aminotransferase. Protein Sci., 26, 2017
5U2R	PRECATALYTIC TERNARY COMPLEX OF HUMAN DNA POLYMERASE BETA WITH GAPPED DNA SUBSTARTE, INCOMING L-DCTP AND CA2+ 分子名称: 10- MER PRIMER, 16- MER TEMPLATE, 4-amino-1-{2-deoxy-5-O-[(R)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-beta-L-erythro-pentofuranosyl}pyrimidin-2(1H)-one, ... 著者 Vyas, R, Suo, Z. 登録日 2016-11-30 公開日 2017-05-24 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural basis for the D-stereoselectivity of human DNA polymerase beta. Nucleic Acids Res., 45, 2017
4S2L	Crystal Structure of OXA-163 beta-lactamase 分子名称: Beta-lactamase, SODIUM ION 著者 Stojanoski, V, Liya, H, Palzkill, T.G, Prasad, B, Sankaran, B. 登録日 2015-01-21 公開日 2015-07-22 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Structural Basis for Different Substrate Profiles of Two Closely Related Class D beta-Lactamases and Their Inhibition by Halogens. Biochemistry, 54, 2015
4ADB	Structural and functional study of succinyl-ornithine transaminase from E. coli 分子名称: MAGNESIUM ION, PYRIDOXAL-5'-PHOSPHATE, SODIUM ION, ... 著者 Newman, J, Peat, T.S. 登録日 2011-12-23 公開日 2013-01-16 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Determination of the Structure of the Catabolic N-Succinylornithine Transaminase (Astc) from Escherichia Coli. Plos One, 8, 2013
5UL5	Crystal structure of RPE65 in complex with MB-004 and palmitate 分子名称: (1R)-3-amino-1-{3-[(2-propylpentyl)oxy]phenyl}propan-1-ol, 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, FE (II) ION, ... 著者 Kiser, P.D, Palczewski, K. 登録日 2017-01-24 公開日 2017-05-17 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Rational Tuning of Visual Cycle Modulator Pharmacodynamics. J. Pharmacol. Exp. Ther., 362, 2017
5UJ6	Crystal Structure of Bacteroides Uniformis beta-glucuronidase 分子名称: CALCIUM ION, GLYCEROL, Glycosyl hydrolases family 2, ... 著者 Walton, W.G, Redinbo, M.R. 登録日 2017-01-17 公開日 2017-06-28 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 An Atlas of beta-Glucuronidases in the Human Intestinal Microbiome. Structure, 25, 2017
5ULN	Synthesis of novel seleno ureido containing compounds as SLC-0111 analogs. Investigations on carbonic anhydrases activity, glutathione peroxidase and X-ray crystallography 分子名称: 4-{[(4-fluorophenyl)carbamothioyl]amino}benzene-1-sulfonamide, Carbonic anhydrase 2, GLYCEROL, ... 著者 Peat, T.S, Angeli, A, Tanini, D, Bartolucci, G, Capperucci, A, Supuran, C.T, Carta, F. 登録日 2017-01-25 公開日 2017-10-11 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Discovery of New Selenoureido Analogues of 4-(4-Fluorophenylureido)benzenesulfonamide as Carbonic Anhydrase Inhibitors. ACS Med Chem Lett, 8, 2017
7LP9	Cryo-EM structure of full-length TRPV1 at 4 degrees Celsius 分子名称: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol, Phosphatidylinositol, ... 著者 Kwon, D.H, Zhang, F, Suo, Y, Lee, S.-Y. 登録日 2021-02-11 公開日 2021-07-28 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (2.63 Å) 主引用文献 Heat-dependent opening of TRPV1 in the presence of capsaicin. Nat.Struct.Mol.Biol., 28, 2021
4PRI	Crystal structure of TK3 TCR-HLA-B*35:08-HPVG complex 分子名称: Beta-2-microglobulin, CHLORIDE ION, Epstein-Barr nuclear antigen 1, ... 著者 Yu Chih, L, Rossjohn, J, Gras, S. 登録日 2014-03-05 公開日 2014-04-16 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 A Molecular Basis for the Interplay between T Cells, Viral Mutants, and Human Leukocyte Antigen Micropolymorphism. J.Biol.Chem., 289, 2014
5ULP	Structure of the NS5 methyltransferase from Zika bound to MS2042 分子名称: 5'-{[(3S)-3-amino-3-carboxypropyl][(4-fluorophenyl)methyl]amino}-5'-deoxyadenosine, CHLORIDE ION, ISOPROPYL ALCOHOL, ... 著者 Jain, R, Aggarwal, A.K. 登録日 2017-01-25 公開日 2017-05-17 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Development of a S-adenosylmethionine analog that intrudes the RNA-cap binding site of Zika methyltransferase. Sci Rep, 7, 2017
5UPZ	HIV-1 wild Type protease with GRL-0518A , an isophthalamide-derived P2-P3 ligand with the para-hydoxymethyl sulfonamide isostere as the P2' group 分子名称: CHLORIDE ION, GLYCEROL, N~3~-{(2S,3R)-3-hydroxy-4-[{[4-(hydroxymethyl)phenyl]sulfonyl}(2-methylpropyl)amino]-1-phenylbutan-2-yl}-N~1~-methyl-N~1~-[(4-methyl-1,3-oxazol-2-yl)methyl]benzene-1,3-dicarboxamide, ... 著者 Wang, Y.-F, Agniswamy, J, Weber, I.T. 登録日 2017-02-05 公開日 2017-05-10 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.27 Å) 主引用文献 Design of novel HIV-1 protease inhibitors incorporating isophthalamide-derived P2-P3 ligands: Synthesis, biological evaluation and X-ray structural studies of inhibitor-HIV-1 protease complex. Bioorg. Med. Chem., 25, 2017

<150151152153154155156157158159160161162163164165>