PDB: 45459 件ウェブページステータス検索Chemie searchBIRD

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6BZF	Structure of S. cerevisiae Zip2:Spo16 complex, C2 form 分子名称: Protein ZIP2, Sporulation-specific protein 16 著者 Arora, K, Corbett, K.D. 登録日 2017-12-23 公開日 2018-02-14 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.286 Å) 主引用文献 The conserved XPF:ERCC1-like Zip2:Spo16 complex controls meiotic crossover formation through structure-specific DNA binding. Nucleic Acids Res., 47, 2019
5JN3	Carbonic Anhydrase IX-mimic IN Complex WITH U-F 分子名称: 4-{[(4-fluorophenyl)carbamoyl]amino}benzenesulfonamide, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... 著者 McKenna, R, Mboge, M.Y, Mahon, B.P. 登録日 2016-04-29 公開日 2017-05-03 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Carbonic Anhydrase IX-mimic IN Complex WITH U-F To Be Published
6GYF	Crystal structure of NadR protein in complex with NR 分子名称: BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, MAGNESIUM ION, Nicotinamide-nucleotide adenylyltransferase NadR family / Ribosylnicotinamide kinase, ... 著者 Singh, R, Stetsenko, A, Jaehme, M, Guskov, A, Slotboom, D.J. 登録日 2018-06-29 公開日 2019-07-10 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural and Functional Characterization of NadR fromLactococcus lactis. Molecules, 25, 2020
6BXU	Crystal Structure of Mouse Protocadherin-15 EC5-7 I582T 分子名称: CALCIUM ION, Protocadherin-15 著者 Neel, B.L, Sotomayor, M. 登録日 2017-12-19 公開日 2018-12-26 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.79 Å) 主引用文献 Structural determinants of protocadherin-15 mechanics and function in hearing and balance perception. Proc.Natl.Acad.Sci.USA, 2020
6GR7	Crystal Structure Of Human Transthyretin in complex with 2,4,5-trichlorophenoxyacetic acid (2,4,5-T) 分子名称: 2-[2,4,5-tris(chloranyl)phenoxy]ethanoic acid, Transthyretin 著者 Grundstrom, C, Zhang, J, Olofsson, A, Andersson, P.L, Sauer-Eriksson, A.E. 登録日 2018-06-09 公開日 2018-07-11 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Interspecies Variation between Fish and Human Transthyretins in Their Binding of Thyroid-Disrupting Chemicals. Environ. Sci. Technol., 52, 2018
5JJE	Structure of the SRII/HtrII Complex in I212121 space group ("U" shape) 分子名称: EICOSANE, RETINAL, Sensory rhodopsin II transducer, ... 著者 Ishchenko, A, Round, E, Borshchevskiy, V, Grudinin, S, Gushchin, I, Klare, J, Remeeva, A, Polovinkin, V, Utrobin, P, Balandin, T, Engelhard, M, Bueldt, G, Gordeliy, V. 登録日 2016-04-23 公開日 2017-02-15 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 New Insights on Signal Propagation by Sensory Rhodopsin II/Transducer Complex. Sci Rep, 7, 2017
6C4Z	Cross-alpha Amyloid-like Structure alphaAmG - low resolution 分子名称: Cross-alpha Amyloid-like Structure alphaAmG - low resolution 著者 Liu, L, Zhang, S.Q. 登録日 2018-01-13 公開日 2018-08-15 最終更新日 2019-12-18 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Designed peptides that assemble into cross-alpha amyloid-like structures. Nat. Chem. Biol., 14, 2018
6GZH	Crystal Structure of Human CDK9/cyclinT1 with A86 分子名称: Cyclin-T1, Cyclin-dependent kinase 9, GLYCEROL, ... 著者 Ben-neriah, Y, Venkatachalam, A, Minzel, W, Fink, A, Snir-Alkalay, I, Vacca, J. 登録日 2018-07-04 公開日 2018-08-29 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.17 Å) 主引用文献 Small Molecules Co-targeting CKI alpha and the Transcriptional Kinases CDK7/9 Control AML in Preclinical Models. Cell, 175, 2018
6ORP	Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch antibody Ab897NHP 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab897NHP antibody Fab heavy chain, ... 著者 Abernathy, M.E, Gristick, H.B, Bjorkman, P.J. 登録日 2019-04-30 公開日 2019-06-12 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques. Nature, 570, 2019
6OSH	Potent and Selective Antitumor Antibody Targeting a Membrane-Proximal Epitope of ROR2 分子名称: Antibody Light chain variable region, Antibody heavy chain variable region, Tyrosine-protein kinase transmembrane receptor ROR2 著者 Park, H, Rader, C. 登録日 2019-05-01 公開日 2020-04-01 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.117 Å) 主引用文献 Affinity maturation, humanization, and co-crystallization of a rabbit anti-human ROR2 monoclonal antibody for therapeutic applications. J.Biol.Chem., 295, 2020
5JMW	Structure of Plasmodium falciparum DXR in complex with a beta-substituted fosmidomycin analogue, LC50 and manganese 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1-deoxy-D-xylulose 5-phosphate reductoisomerase, ... 著者 Sooriyaarachchi, S, Bergfors, T, Jones, T.A, Mowbray, S.L. 登録日 2016-04-29 公開日 2016-08-24 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Targeting an Aromatic Hotspot in Plasmodium falciparum 1-Deoxy-d-xylulose-5-phosphate Reductoisomerase with beta-Arylpropyl Analogues of Fosmidomycin. Chemmedchem, 11, 2016
6Z1H	Ancestral glycosidase (family 1) 分子名称: ANCESTRAL RECONSTRUCTED GLYCOSIDASE, GLYCEROL, ISOPROPYL ALCOHOL, ... 著者 Gavira, J.A, Risso, V.A, Sanchez-Ruiz, J.M, Gamiz-Arco, G, Gutierrez-Rus, L, Ibarra-Molero, B, Hoshino, Y, Petrovic, D, Romero-Rivera, A, Seelig, B, Kamerlin, S.C.L, Gaucher, E.A. 登録日 2020-05-13 公開日 2020-07-22 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Heme-binding enables allosteric modulation in an ancient TIM-barrel glycosidase. Nat Commun, 12, 2021
5JHE	The Crystal Structure of the Saccharomyces cerevisiae Co-Chaperone Cpr7 分子名称: Peptidyl-prolyl cis-trans isomerase CYP7 著者 Yu, Q, Xu, L. 登録日 2016-04-20 公開日 2017-04-26 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The Crystal Structure of the Saccharomyces cerevisiae Co-Chaperone Cpr7 To Be Published
6OSY	Cryo-EM structure of vaccine-elicited antibody 0PV-a.01 in complex with HIV-1 Env BG505 DS-SOSIP and antibodies VRC03 and PGT122 分子名称: 0PV-a.01 Heavy, 0PV-a.01 Light, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Gorman, J, Kwong, P.D. 登録日 2019-05-02 公開日 2019-07-24 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization. Cell, 178, 2019
5JNC	Crystal structure for the complex of human carbonic anhydrase IV and 4-aminomethylbenzene sulfonamide 分子名称: 4-(aminomethyl)benzene-1-sulfonamide, ACETATE ION, Carbonic anhydrase 4, ... 著者 Chen, Z, Waheed, A, Di Cera, E, Sly, W.S. 登録日 2016-04-29 公開日 2017-05-03 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Intrinsic thermodynamics of high affinity inhibitor binding to recombinant human carbonic anhydrase IV. Eur. Biophys. J., 47, 2018
5JI0	PPARgamma-RXRalpha(S427F) heterodimer in complex with SRC-1, rosiglitazone, and 9-cis-retanoic acid 分子名称: (9cis)-retinoic acid, 2,4-THIAZOLIDIINEDIONE, 5-[[4-[2-(METHYL-2-PYRIDINYLAMINO)ETHOXY]PHENYL]METHYL]-(9CL), ... 著者 Bloudoff, K, Larsen, N.A. 登録日 2016-04-21 公開日 2017-04-26 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 PPARgamma-RXRalpha(S427F) heterodimer in complex with SRC-1, rosiglitazone, and 9-cis-retanoic acid To Be Published
6OV0	Crystal structure of Csm6 in complex with A4>p by soaking A4>p into Csm6 分子名称: RNA (5'-R(*AP*AP*AP*(A23))-3'), Uncharacterized protein 著者 Jia, N, Patel, D.J. 登録日 2019-05-06 公開日 2019-07-31 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 CRISPR-Cas III-A Csm6 CARF Domain Is a Ring Nuclease Triggering Stepwise cA4Cleavage with ApA>p Formation Terminating RNase Activity. Mol.Cell, 75, 2019
6QDG	Leishmania major N-myristoyltransferase in complex with quinazoline inhibitor IMP-0000169 分子名称: 3-[[6-bromanyl-2-[3-(dimethylamino)propyl-methyl-amino]quinazolin-4-yl]-methyl-amino]propanenitrile, Glycylpeptide N-tetradecanoyltransferase, MAGNESIUM ION, ... 著者 Brannigan, J.A. 登録日 2019-01-01 公開日 2020-05-06 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Novel Thienopyrimidine Inhibitors of Leishmania N -Myristoyltransferase with On-Target Activity in Intracellular Amastigotes. J.Med.Chem., 63, 2020
2N58	Structure of an N-terminal membrane-anchoring region of the glycosyltransferase WaaG 分子名称: Lipopolysaccharide core biosynthesis protein RfaG 著者 Liebau, J, Pettersson, P, Szpryngiel, S, Maler, L. 登録日 2015-07-13 公開日 2015-08-19 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Membrane Interaction of the Glycosyltransferase WaaG. Biophys.J., 109, 2015
5JJN	Structure of the SRII/HtrII(G83F) Complex in P212121 space group ("V" shape) 分子名称: EICOSANE, RETINAL, Sensory rhodopsin II transducer, ... 著者 Ishchenko, A, Round, E, Borshchevskiy, V, Grudinin, S, Gushchin, I, Klare, J, Remeeva, A, Polovinkin, V, Utrobin, P, Balandin, T, Engelhard, M, Bueldt, G, Gordeliy, V. 登録日 2016-04-24 公開日 2017-02-15 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 New Insights on Signal Propagation by Sensory Rhodopsin II/Transducer Complex. Sci Rep, 7, 2017
5JLT	The crystal structure of the bacteriophage T4 MotA C-terminal domain in complex with dsDNA reveals a novel protein-DNA recognition motif 分子名称: DNA (5'-D(*GP*AP*AP*GP*CP*TP*TP*TP*GP*CP*TP*TP*AP*AP*TP*AP*AP*TP*CP*CP*AP*C)-3'), DNA (5'-D(*GP*TP*GP*GP*AP*TP*TP*AP*TP*TP*AP*AP*GP*CP*AP*AP*AP*GP*CP*TP*TP*C)-3'), Middle transcription regulatory protein motA 著者 Cuypers, M.G, Robertson, R.M, Knipling, L, Hinton, D.M, White, S.W. 登録日 2016-04-27 公開日 2017-05-03 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.955 Å) 主引用文献 The phage T4 MotA transcription factor contains a novel DNA binding motif that specifically recognizes modified DNA. Nucleic Acids Res., 46, 2018
6FEW	DDR1, 2-[8-(1H-indazole-5-carbonyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-3-yl]-N-methylacetamide, 1.440A, P1211, Rfree=24.1% 分子名称: 2-[8-(2~{H}-indazol-5-ylcarbonyl)-4-oxidanylidene-1-phenyl-1,3,8-triazaspiro[4.5]decan-3-yl]-~{N}-methyl-ethanamide, Epithelial discoidin domain-containing receptor 1 著者 Stihle, M, Richter, H, Benz, J, Kuhn, B, Rudolph, M.G. 登録日 2018-01-03 公開日 2018-11-28 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.44 Å) 主引用文献 DNA-Encoded Library-Derived DDR1 Inhibitor Prevents Fibrosis and Renal Function Loss in a Genetic Mouse Model of Alport Syndrome. Acs Chem.Biol., 14, 2019
5JMZ	Carbonic Anhydrase IX-mimic IN Complex WITH U-NO2 分子名称: 4-{[(3-nitrophenyl)carbamoyl]amino}benzenesulfonamide, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... 著者 McKenna, R, Mboge, M.Y, Mahon, B.P. 登録日 2016-04-29 公開日 2017-05-03 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Carbonic Anhydrase IX-mimic IN Complex WITH U-NO2 To Be Published
5JNA	Crystal structure for the complex of human carbonic anhydrase IV and topiramate 分子名称: ACETATE ION, Carbonic anhydrase 4, GLYCEROL, ... 著者 Chen, Z, Waheed, A, Di Cera, E, Sly, W.S. 登録日 2016-04-29 公開日 2017-05-03 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Intrinsic thermodynamics of high affinity inhibitor binding to recombinant human carbonic anhydrase IV. Eur. Biophys. J., 47, 2018
5J4P	DIY G-Quadruplexes: Solution structure of d(GGTTTGGTTTTGGTTTGG) in sodium 分子名称: DNA (5'-D(*GP*GP*TP*TP*TP*GP*GP*TP*TP*TP*TP*GP*GP*TP*TP*TP*GP*G)-3') 著者 Dvorkin, S.A, Webba da Silva, M. 登録日 2016-04-01 公開日 2017-06-14 最終更新日 2024-06-19 実験手法 SOLUTION NMR 主引用文献 Encoding canonical DNA quadruplex structure. Sci Adv, 4, 2018

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