6GR7

Crystal Structure Of Human Transthyretin in complex with 2,4,5-trichlorophenoxyacetic acid (2,4,5-T)

Summary for 6GR7

Entry DOI	10.2210/pdb6gr7/pdb
Descriptor	Transthyretin, 2-[2,4,5-tris(chloranyl)phenoxy]ethanoic acid (3 entities in total)
Functional Keywords	transthyretin, transport protein, thyroxine disrupting chemicals, tdcs, 2, 4, 5-trichlorophenoxyacetic acid, 5-t
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	28065.68
Authors	Grundstrom, C.,Zhang, J.,Olofsson, A.,Andersson, P.L.,Sauer-Eriksson, A.E. (deposition date: 2018-06-09, release date: 2018-07-11, Last modification date: 2024-01-17)
Primary citation	Zhang, J.,Grundstrom, C.,Brannstrom, K.,Iakovleva, I.,Lindberg, M.,Olofsson, A.,Andersson, P.L.,Sauer-Eriksson, A.E. Interspecies Variation between Fish and Human Transthyretins in Their Binding of Thyroid-Disrupting Chemicals. Environ. Sci. Technol., 52:11865-11874, 2018 Cited by PubMed: 30226982 DOI: 10.1021/acs.est.8b03581 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.4 Å)

Structure validation