PDB: 8880 件ウェブページステータス検索Chemie searchBIRD

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2ERM	Solution structure of a biologically active human FGF-1 monomer, complexed to a hexasaccharide heparin-analogue 分子名称: 2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-acetamido-2-deoxy-6-O-sulfo-alpha-D-glucopyranose-(1-4)-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, Heparin-binding growth factor 1, ISOPROPYL ALCOHOL 著者 Canales, A, Lozano, R, Nieto, P.M, Martin-Lomas, M, Gimenez-Gallego, G, Jimenez-Barbero, J. 登録日 2005-10-25 公開日 2006-10-03 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Solution NMR structure of a human FGF-1 monomer, activated by a hexasaccharide heparin-analogue. Febs J., 273, 2006
2L3Y	Solution structure of mouse IL-6 分子名称: Interleukin-6 著者 Veverka, V, Redpath, N.T, Carrington, B, Muskett, F.W, Taylor, R.J, Henry, A.J, Carr, M.D. 登録日 2010-09-25 公開日 2011-09-28 最終更新日 2013-01-02 実験手法 SOLUTION NMR 主引用文献 Conservation of functional sites on interleukin-6 and implications for evolution of signaling complex assembly and therapeutic intervention. J.Biol.Chem., 287, 2012
1PVH	Crystal structure of leukemia inhibitory factor in complex with gp130 分子名称: IODIDE ION, Interleukin-6 receptor beta chain, Leukemia inhibitory factor 著者 Boulanger, M.J, Bankovich, A.J, Kortemme, T, Baker, D, Garcia, K.C. 登録日 2003-06-27 公開日 2003-10-14 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Convergent mechanisms for recognition of divergent cytokines by the shared signaling receptor gp130. Mol.Cell, 12, 2003
6HG9	Crystal Structure of the human IL-17RC ECD in complex with human IL-17F, Crystal form II 分子名称: Interleukin-17 receptor C, Interleukin-17F 著者 Rondeau, J.M, Goepfert, A. 登録日 2018-08-23 公開日 2020-03-18 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.62 Å) 主引用文献 Structural Analysis Reveals that the Cytokine IL-17F Forms a Homodimeric Complex with Receptor IL-17RC to Drive IL-17RA-Independent Signaling. Immunity, 52, 2020
1RO4	RDC-derived models of the zinc ribbon domain of human general transcription factor TFIIB (zinc free structures) 分子名称: Transcription initiation factor IIB 著者 Ghosh, M, Ikura, M. 登録日 2003-12-01 公開日 2004-05-25 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Probing Zn2+-binding effects on the zinc-ribbon domain of human general transcription factor TFIIB. Biochem.J., 378, 2004
1RLY	RDC-derived models of the zinc ribbon domain of human general transcription TFIIB (zinc bound structures) 分子名称: Transcription initiation factor IIB, ZINC ION 著者 Ghosh, M, Ikura, M. 登録日 2003-11-26 公開日 2004-05-25 最終更新日 2022-03-02 実験手法 SOLUTION NMR 主引用文献 Probing Zn2+-binding effects on the zinc-ribbon domain of human general transcription factor TFIIB. Biochem.J., 378, 2004
8P81	Crystal structure of human Cdk12/Cyclin K in complex with inhibitor SR-4835 分子名称: Cyclin-K, Cyclin-dependent kinase 12, ~{N}-[[5,6-bis(chloranyl)-1~{H}-benzimidazol-2-yl]methyl]-9-(1-methylpyrazol-4-yl)-2-morpholin-4-yl-purin-6-amine 著者 Anand, K, Schmitz, M, Geyer, M. 登録日 2023-05-31 公開日 2023-11-22 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.68 Å) 主引用文献 The reversible inhibitor SR-4835 binds Cdk12/cyclin K in a noncanonical G-loop conformation. J.Biol.Chem., 300, 2023
3ZG1	NI-BOUND FORM OF M123A MUTANT OF CUPRIAVIDUS METALLIDURANS CH34 CNRXS 分子名称: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Girard, E, Coves, J. 登録日 2012-12-13 公開日 2013-10-23 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Metal Sensing and Signal Transduction by Cnrx from Cupriavidus Metallidurans Ch34: Role of the Only Methionine Assessed by a Functional, Spectroscopic, and Theoretical Study Metallomics, 6, 2014
1JVP	Crystal structure of human CDK2 (unphosphorylated) in complex with PKF049-365 分子名称: 3-pyridin-4-yl-2,4-dihydroindeno[1,2-c]pyrazole, Cell division protein kinase 2 著者 Rondeau, J.M. 登録日 2001-08-31 公開日 2001-12-21 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Structure-based design and protein X-ray analysis of a protein kinase inhibitor. Bioorg.Med.Chem.Lett., 12, 2002
1C20	SOLUTION STRUCTURE OF THE DNA-BINDING DOMAIN FROM THE DEAD RINGER PROTEIN 分子名称: DEAD RINGER PROTEIN 著者 Iwahara, J, Clubb, R.T. 登録日 1999-07-22 公開日 1999-11-10 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Solution structure of the DNA binding domain from Dead ringer, a sequence-specific AT-rich interaction domain (ARID). EMBO J., 18, 1999
1TIV	STRUCTURAL STUDIES OF HIV-1 TAT PROTEIN 分子名称: HIV-1 TRANSACTIVATOR PROTEIN 著者 Bayer, P, Kraft, M, Frank, R, Roesch, P. 登録日 1995-02-14 公開日 1995-07-31 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Structural studies of HIV-1 Tat protein. J.Mol.Biol., 247, 1995
4DTJ	RB69 DNA Polymerase Ternary Complex with dTTP Opposite an Abasic Site and ddT/dA as the Penultimate Base-pair 分子名称: CALCIUM ION, DNA polymerase, DNA primer, ... 著者 Xia, S, Wang, J, Konigsberg, W.H. 登録日 2012-02-21 公開日 2012-06-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Contribution of Partial Charge Interactions and Base Stacking to the Efficiency of Primer Extension at and beyond Abasic Sites in DNA. Biochemistry, 51, 2012
4DTO	RB69 DNA Polymerase Ternary Complex with dCTP Opposite an Abasic Site and ddA/dT as the Penultimate Base-pair 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... 著者 Xia, S, Wang, J, Konigsberg, W.H. 登録日 2012-02-21 公開日 2012-06-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Contribution of Partial Charge Interactions and Base Stacking to the Efficiency of Primer Extension at and beyond Abasic Sites in DNA. Biochemistry, 51, 2012
4DTR	RB69 DNA Polymerase Ternary Complex with dATP Opposite an Abasic Site and ddC/dG as the Penultimate Base-pair 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... 著者 Xia, S, Wang, J, Konigsberg, W.H. 登録日 2012-02-21 公開日 2012-06-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Contribution of Partial Charge Interactions and Base Stacking to the Efficiency of Primer Extension at and beyond Abasic Sites in DNA. Biochemistry, 51, 2012
4DTM	RB69 DNA Polymerase Ternary Complex with dCTP Opposite an Abasic Site and ddG/dC as the Penultimate Base-pair 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... 著者 Xia, S, Wang, J, Konigsberg, W.H. 登録日 2012-02-21 公開日 2012-06-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Contribution of Partial Charge Interactions and Base Stacking to the Efficiency of Primer Extension at and beyond Abasic Sites in DNA. Biochemistry, 51, 2012
4DTP	RB69 DNA Polymerase Ternary Complex with dGTP Opposite an Abasic Site and ddA/dT as the Penultimate Base-pair 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... 著者 Xia, S, Wang, J, Konigsberg, W.H. 登録日 2012-02-21 公開日 2012-06-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Contribution of Partial Charge Interactions and Base Stacking to the Efficiency of Primer Extension at and beyond Abasic Sites in DNA. Biochemistry, 51, 2012
4DTN	RB69 DNA Polymerase Ternary Complex with dATP Opposite an Abasic Site and ddA/dT as the Penultimate Base-pair 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... 著者 Xia, S, Wang, J, Konigsberg, W.H. 登録日 2012-02-21 公開日 2012-06-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Contribution of Partial Charge Interactions and Base Stacking to the Efficiency of Primer Extension at and beyond Abasic Sites in DNA. Biochemistry, 51, 2012
4DTS	RB69 DNA Polymerase Ternary Complex with dCTP Opposite an Abasic Site and ddC/dG as the Penultimate Base-pair 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... 著者 Xia, S, Wang, J, Konigsberg, W.H. 登録日 2012-02-21 公開日 2012-06-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Contribution of Partial Charge Interactions and Base Stacking to the Efficiency of Primer Extension at and beyond Abasic Sites in DNA. Biochemistry, 51, 2012
4DTU	RB69 DNA Polymerase Ternary Complex with dGTP Opposite an Abasic Site and ddC/dG as the Penultimate Base-pair 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... 著者 Xia, S, Wang, J, Konigsberg, W.H. 登録日 2012-02-21 公開日 2012-06-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Contribution of Partial Charge Interactions and Base Stacking to the Efficiency of Primer Extension at and beyond Abasic Sites in DNA. Biochemistry, 51, 2012
4O19	The crystal structure of a mutant NAMPT (G217V) 分子名称: 1,2-ETHANEDIOL, Nicotinamide phosphoribosyltransferase, PHOSPHATE ION 著者 Oh, A, Coons, M, Brillantes, B, Wang, W. 登録日 2013-12-15 公開日 2014-10-22 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structural Basis for Resistance to Diverse Classes of NAMPT Inhibitors. Plos One, 9, 2014
4O13	The crystal structure of NAMPT in complex with GNE-618 分子名称: 1,2-ETHANEDIOL, N-(4-{[3-(trifluoromethyl)phenyl]sulfonyl}benzyl)-2H-pyrazolo[3,4-b]pyridine-5-carboxamide, Nicotinamide phosphoribosyltransferase, ... 著者 Oh, A, Coons, M, Brillantes, B, Wang, W. 登録日 2013-12-15 公開日 2014-10-22 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structural Basis for Resistance to Diverse Classes of NAMPT Inhibitors. Plos One, 9, 2014
8K6Z	NMR structure of human leptin 分子名称: Leptin 著者 Fan, X, Qin, R, Yuan, W, Fan, J, Huang, W, Lin, Z. 登録日 2023-07-26 公開日 2024-02-07 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 The solution structure of human leptin reveals a conformational plasticity important for receptor recognition. Structure, 32, 2024
3A03	Crystal structure of Hox11L1 homeodomain 分子名称: SODIUM ION, SULFATE ION, T-cell leukemia homeobox protein 2 著者 Miyazono, K, Nagata, K, Saigo, K, Kojima, T, Tanokura, M. 登録日 2009-02-28 公開日 2010-03-09 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 Cooperative DNA-binding and sequence-recognition mechanism of aristaless and clawless Embo J., 29, 2010
3A02	Crystal structure of Aristaless homeodomain 分子名称: CADMIUM ION, CHLORIDE ION, Homeobox protein aristaless 著者 Miyazono, K, Nagata, K, Saigo, K, Kojima, T, Tanokura, M. 登録日 2009-02-28 公開日 2010-03-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1 Å) 主引用文献 Cooperative DNA-binding and sequence-recognition mechanism of aristaless and clawless Embo J., 29, 2010
3A01	Crystal structure of Aristaless and Clawless homeodomains bound to DNA 分子名称: 5'-D(*CP*CP*GP*CP*AP*AP*TP*TP*AP*AP*TP*TP*AP*AP*GP*CP*C)-3', 5'-D(*GP*GP*CP*TP*TP*AP*AP*TP*TP*AP*AP*TP*TP*GP*CP*GP*G)-3', Homeobox protein aristaless, ... 著者 Miyazono, K, Nagata, K, Saigo, K, Kojima, T, Tanokura, M. 登録日 2009-02-28 公開日 2010-03-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Cooperative DNA-binding and sequence-recognition mechanism of aristaless and clawless Embo J., 29, 2010

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