PDB: 42250 件ウェブページステータス検索Chemie searchBIRD

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7ZO6	L1 metallo-beta-lactamase in complex with hydrolysed cefoxitin 分子名称: (2~{R},5~{S})-5-(aminocarbonyloxymethyl)-2-[(1~{S})-1-methoxy-2-oxidanyl-2-oxidanylidene-1-(2-thiophen-2-ylethanoylamino)ethyl]-5,6-dihydro-2~{H}-1,3-thiazine-4-carboxylic acid, Metallo-beta-lactamase L1, SULFATE ION, ... 著者 Hinchliffe, P, Spencer, J. 登録日 2022-04-24 公開日 2023-03-08 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (1.61 Å) 主引用文献 Interactions of hydrolyzed beta-lactams with the L1 metallo-beta-lactamase: Crystallography supports stereoselective binding of cephem/carbapenem products. J.Biol.Chem., 299, 2023
8OIP	28S mammalian mitochondrial small ribosomal subunit with mtRF1 and P-site tRNA 分子名称: 12S rRNA, 28S ribosomal protein S15, mitochondrial, ... 著者 Saurer, M, Leibundgut, M, Scaiola, A, Schoenhut, T, Ban, N. 登録日 2023-03-23 公開日 2023-05-24 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Molecular basis of translation termination at noncanonical stop codons in human mitochondria. Science, 380, 2023
8OIS	28S human mitochondrial small ribosomal subunit with mtRF1 and P-site tRNA 分子名称: 12S rRNA, 28S ribosomal protein S10, mitochondrial, ... 著者 Saurer, M, Leibundgut, M, Scaiola, A, Schoenhut, T, Ban, N. 登録日 2023-03-23 公開日 2023-06-14 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Molecular basis of translation termination at noncanonical stop codons in human mitochondria. Science, 380, 2023
8OIT	39S human mitochondrial large ribosomal subunit with mtRF1 and P-site tRNA 分子名称: 16S rRNA, 39S ribosomal protein L1, mitochondrial, ... 著者 Saurer, M, Leibundgut, M, Scaiola, A, Schoenhut, T, Ban, N. 登録日 2023-03-23 公開日 2023-06-14 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Molecular basis of translation termination at noncanonical stop codons in human mitochondria. Science, 380, 2023
7E24	Crystal structure of SDR family NAD(P)-dependent oxidoreductase from Exiguobacterium 分子名称: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Oxidoreductase 著者 Chen, L, Tang, J, Yuan, S. 登録日 2021-02-04 公開日 2021-09-29 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.7203 Å) 主引用文献 Structure-guided evolution of a ketoreductase forefficient and stereoselective bioreduction of bulkyalpha-aminobeta-keto esters Catalysis Science And Technology, 2021
7E3X	Crystal structure of SDR family NAD(P)-dependent oxidoreductase from exiguobacterium 分子名称: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Oxidoreductase 著者 Chen, L, Tang, J, Yuan, S, Zhang, F, Chen, S. 登録日 2021-02-09 公開日 2021-09-29 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.58 Å) 主引用文献 Structure-guided evolution of a ketoreductase forefficient and stereoselective bioreduction of bulkyalpha-aminobeta-keto esters Catalysis Science And Technology, 2021
8XBD	GH18 family chitinase from cold seep metagenome 分子名称: GH18 chitinase-like superfamily protein 著者 Yang, J. 登録日 2023-12-06 公開日 2023-12-27 最終更新日 2025-04-30 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Exploring the role of organotrophic microbes in geochemical cycling of cold seep sediments. Innov Geosci, 3, 2025
7ZPM	Influenza A/H7N9 polymerase apo-protein dimer complex 分子名称: Polymerase acidic protein, Polymerase basic protein 2, RNA-directed RNA polymerase catalytic subunit 著者 Cusack, S, Kouba, T. 登録日 2022-04-27 公開日 2022-12-28 最終更新日 2025-07-02 実験手法 ELECTRON MICROSCOPY (2.81 Å) 主引用文献 Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106. Cell Rep, 42, 2023
7ZPL	Symmetric dimer of influenza A/H7N9 polymerase bound to 5' vRNA hook 分子名称: 5' vRNA, MAGNESIUM ION, Polymerase acidic protein, ... 著者 Cusack, S, Kouba, T. 登録日 2022-04-27 公開日 2022-12-28 最終更新日 2025-07-02 実験手法 ELECTRON MICROSCOPY (3.12 Å) 主引用文献 Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106. Cell Rep, 42, 2023
7BHY	DNA-binding domain of DeoR in complex with the DNA operator 分子名称: DNA operator - strand 1, DNA operator - strand 2, Deoxyribonucleoside regulator, ... 著者 Novakova, M, Rezacova, P, Skerlova, J, Brynda, J. 登録日 2021-01-11 公開日 2021-11-10 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural insight into DNA recognition by bacterial transcriptional regulators of the SorC/DeoR family. Acta Crystallogr D Struct Biol, 77, 2021
7F3P	Crystal structure of a nadp-dependent alcohol dehydrogenase mutant in apo form 分子名称: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NADP-dependent isopropanol dehydrogenase, ZINC ION 著者 Han, X, Bi, Y, Wei, H.L, Gao, J, Li, Q, Qu, G, Sun, Z.T, Liu, W.D. 登録日 2021-06-16 公開日 2021-10-27 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Unlocking the Stereoselectivity and Substrate Acceptance of Enzymes: Proline-Induced Loop Engineering Test. Angew.Chem.Int.Ed.Engl., 61, 2022
7VP9	Crystal structure of human ClpP in complex with ZG111 分子名称: (6S,9aS)-N-[(4-bromophenyl)methyl]-6-[(2S)-butan-2-yl]-8-(naphthalen-1-ylmethyl)-4,7-bis(oxidanylidene)-3,6,9,9a-tetrahydro-2H-pyrazino[1,2-a]pyrimidine-1-carboxamide, ATP-dependent Clp protease proteolytic subunit, mitochondrial, ... 著者 Wang, P.Y, Gan, J.H, Yang, C.-G. 登録日 2021-10-15 公開日 2022-06-08 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.552 Å) 主引用文献 Aberrant human ClpP activation disturbs mitochondrial proteome homeostasis to suppress pancreatic ductal adenocarcinoma. Cell Chem Biol, 29, 2022
7MER	Structure of ALDH4A1 complexed with trans-4-Hydroxy-L-proline 分子名称: 4-HYDROXYPROLINE, DI(HYDROXYETHYL)ETHER, Delta-1-pyrroline-5-carboxylate dehydrogenase, ... 著者 Bogner, A.N, Stiers, K.M, Tanner, J.J. 登録日 2021-04-07 公開日 2021-06-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Structural basis for the stereospecific inhibition of the dual proline/hydroxyproline catabolic enzyme ALDH4A1 by trans-4-hydroxy-L-proline. Protein Sci., 30, 2021
7MES	Structure of ALDH4A1 complexed with trans-4-Hydroxy-D-proline 分子名称: (4S)-4-hydroxy-D-proline, DI(HYDROXYETHYL)ETHER, Delta-1-pyrroline-5-carboxylate dehydrogenase, ... 著者 Bogner, A.N, Stiers, K.M, Tanner, J.J. 登録日 2021-04-07 公開日 2021-06-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.37 Å) 主引用文献 Structural basis for the stereospecific inhibition of the dual proline/hydroxyproline catabolic enzyme ALDH4A1 by trans-4-hydroxy-L-proline. Protein Sci., 30, 2021
7KCS	The crystal structure of 4-vinylbenzoate-bound wild-type CYP199A4 分子名称: 4-ethenylbenzoic acid, CHLORIDE ION, Cytochrome P450, ... 著者 Coleman, T, Bruning, J.B, Bell, S.G. 登録日 2020-10-07 公開日 2021-05-19 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.773 Å) 主引用文献 Understanding the Mechanistic Requirements for Efficient and Stereoselective Alkene Epoxidation by a Cytochrome P450 Enzyme Acs Catalysis, 11, 2021
7XDQ	Crystal structure of a glucosylglycerol phosphorylase mutant from Marinobacter adhaerens 分子名称: Glucosylglycerol phosphorylase, LITHIUM ION, beta-D-glucopyranose 著者 Wei, H.L, Li, Q, Yang, J.G, Liu, W.D, Sun, Y.X. 登録日 2022-03-28 公開日 2023-02-08 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.83 Å) 主引用文献 Protein Engineering of Glucosylglycerol Phosphorylase Facilitating Efficient and Highly Regio- and Stereoselective Glycosylation of Polyols in a Synthetic System. Acs Catalysis, 2022
7XDR	Crystal structure of a glucosylglycerol phosphorylase from Marinobacter adhaerens 分子名称: Glucosylglycerol phosphorylase 著者 Wei, H.L, Li, Q, Yang, J.G, Liu, W.D, Sun, Y.X. 登録日 2022-03-28 公開日 2023-02-08 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Protein Engineering of Glucosylglycerol Phosphorylase Facilitating Efficient and Highly Regio- and Stereoselective Glycosylation of Polyols in a Synthetic System. Acs Catalysis, 2022
8S90	Cryo-EM structure of octameric human CALHM1 (I109W) in complex with ruthenium red (C1) 分子名称: Calcium homeostasis modulator protein 1, ruthenium(6+) azanide pentaamino(oxido)ruthenium (1/4/2) 著者 Syrjanen, J.L, Furukawa, H. 登録日 2023-03-27 公開日 2023-07-26 最終更新日 2024-11-13 実験手法 ELECTRON MICROSCOPY (4.73 Å) 主引用文献 Structure of human CALHM1 reveals key locations for channel regulation and blockade by ruthenium red. Nat Commun, 14, 2023
8S8Z	Cryo-EM structure of octameric human CALHM1 (I109W) in complex with ruthenium red 分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Calcium homeostasis modulator protein 1, ruthenium(6+) azanide pentaamino(oxido)ruthenium (1/4/2) 著者 Syrjanen, J.L, Furukawa, H. 登録日 2023-03-27 公開日 2023-07-26 最終更新日 2024-11-06 実験手法 ELECTRON MICROSCOPY (3.91 Å) 主引用文献 Structure of human CALHM1 reveals key locations for channel regulation and blockade by ruthenium red. Nat Commun, 14, 2023
9CIQ	Crystal structure of human polymerase eta with incoming threofuranosyl thymine nucleoside triphosphate opposite template dA 分子名称: CALCIUM ION, DI(HYDROXYETHYL)ETHER, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... 著者 Patra, A, Tomar, R, Stone, M.P, Egli, M. 登録日 2024-07-04 公開日 2024-09-18 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 DNA Replication across alpha-l-(3'-2')-Threofuranosyl Nucleotides Mediated by Human DNA Polymerase eta. Biochemistry, 63, 2024
9CP7	Crystal structure of DHPS-3-dehydrogenase, HpsN from Cupriavidus pinatubonensis in complex with product analogue (L-cysteate) and NADH 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, CYSTEINESULFONIC ACID, Sulfopropanediol 3-dehydrogenase, ... 著者 Lee, M. 登録日 2024-07-18 公開日 2024-09-25 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (1.751 Å) 主引用文献 Structural and kinetic insights into the stereospecific oxidation of R -2,3-dihydroxypropanesulfonate by DHPS-3-dehydrogenase from Cupriavidus pinatubonensis. Chem Sci, 15, 2024
9CP8	Crystal structure of DHPS-3-dehydrogenase, HpsN from Cupriavidus pinatubonensis in complex with product (R-sulfolactate) and NADH 分子名称: (2R)-3-SULFOLACTIC ACID, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Sulfopropanediol 3-dehydrogenase, ... 著者 Lee, M. 登録日 2024-07-18 公開日 2024-09-25 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 Structural and kinetic insights into the stereospecific oxidation of R -2,3-dihydroxypropanesulfonate by DHPS-3-dehydrogenase from Cupriavidus pinatubonensis. Chem Sci, 15, 2024
9CP9	Crystal structure of DHPS-3-dehydrogenase, HpsN H319A variant from Cupriavidus pinatubonensis in complex with substrate (R-DHPS) and NADH 分子名称: (2R)-2,3-dihydroxypropane-1-sulfonic acid, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, SULFATE ION, ... 著者 Lee, M. 登録日 2024-07-18 公開日 2024-09-25 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.013 Å) 主引用文献 Structural and kinetic insights into the stereospecific oxidation of R -2,3-dihydroxypropanesulfonate by DHPS-3-dehydrogenase from Cupriavidus pinatubonensis. Chem Sci, 15, 2024
5EOS	Crystallizing Strained DNA: Self-Assembly of 3D Crystals Containing a Torsionally-Stressed Component 分子名称: DNA (5'-D(*TP*CP*TP*GP*AP*TP*GP*TP*GP*CP*TP*GP*C)-3'), DNA (5'-D(P*AP*CP*GP*GP*AP*CP*AP*TP*CP*A)-3'), DNA (5'-D(P*CP*AP*CP*AP*CP*CP*GP*T)-3'), ... 著者 Hernandez, C, Birktoft, J.J, Seeman, N.C. 登録日 2015-11-10 公開日 2017-08-09 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (4.7 Å) 主引用文献 Self-Assembly of 3D DNA Crystals Containing a Torsionally Stressed Component. Cell Chem Biol, 2017
3EOS	tRNA-guanine transglycosylase in complex with 6-amino-4-{2-[(cyclohexylmethyl)amino]ethyl}-2-(methylamino)-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one 分子名称: 6-amino-4-{2-[(cyclohexylmethyl)amino]ethyl}-2-(methylamino)-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one, GLYCEROL, Queuine tRNA-ribosyltransferase, ... 著者 Ritschel, T, Heine, A, Klebe, G. 登録日 2008-09-29 公開日 2009-09-15 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 How to Replace the Residual Solvation Shell of Polar Active Site Residues to Achieve Nanomolar Inhibition of tRNA-Guanine Transglycosylase Chemmedchem, 4, 2009

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