PDB: 225946 件ウェブページステータス検索Chemie searchBIRD

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2H4G	Crystal structure of PTP1B with monocyclic thiophene inhibitor 分子名称: 4-BROMO-3-(CARBOXYMETHOXY)-5-(4-HYDROXYPHENYL)THIOPHENE-2-CARBOXYLIC ACID, Tyrosine-protein phosphatase non-receptor type 1 著者 Xu, W, Wan, Z.-K. 登録日 2006-05-24 公開日 2006-08-29 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Monocyclic thiophenes as protein tyrosine phosphatase 1B inhibitors: Capturing interactions with Asp48. Bioorg.Med.Chem.Lett., 16, 2006
2H4H	Sir2 H116Y mutant-p53 peptide-NAD 分子名称: Cellular tumor antigen p53, NAD-dependent deacetylase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... 著者 Hoff, K.G, Avalos, J.L, Sens, K, Wolberger, C. 登録日 2006-05-24 公開日 2006-09-05 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Insights into the Sirtuin Mechanism from Ternary Complexes Containing NAD(+) and Acetylated Peptide. Structure, 14, 2006
2H4I	Crystal structure of the complex of proteolytically produced C-terminal half of bovine lactoferrin with lactose at 2.55 A resolution 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, FE (III) ION, ... 著者 Mir, R, Prem kumar, R, Sinha, M, Singh, N, Kaur, P, Sharma, S, Singh, T.P. 登録日 2006-05-24 公開日 2006-06-13 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Crystal structure of the complex of proteolytically produced C-terminal half of bovine lactoferrin with lactose at 2.55 A resolution To be Published
2H4J	Sir2-deacetylated peptide (from enzymatic turnover in crystal) 分子名称: 2'-O-ACETYL ADENOSINE-5-DIPHOSPHORIBOSE, Cellular tumor antigen p53, NAD-dependent deacetylase, ... 著者 Hoff, K.G, Avalos, J.L, Sens, K, Wolberger, C. 登録日 2006-05-24 公開日 2006-09-05 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Insights into the Sirtuin Mechanism from Ternary Complexes Containing NAD(+) and Acetylated Peptide. Structure, 14, 2006
2H4K	Crystal structure of PTP1B with a monocyclic thiophene inhibitor 分子名称: 4-BROMO-3-(CARBOXYMETHOXY)-5-PHENYLTHIOPHENE-2-CARBOXYLIC ACID, Tyrosine-protein phosphatase non-receptor type 1 著者 Xu, W, Wan, Z.-K. 登録日 2006-05-24 公開日 2006-08-29 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Monocyclic thiophenes as protein tyrosine phosphatase 1B inhibitors: Capturing interactions with Asp48. Bioorg.Med.Chem.Lett., 16, 2006
2H4L	Complex of PMM/PGM with ribose 1-phosphate 分子名称: 1-O-phosphono-alpha-D-ribofuranose, Phosphomannomutase/phosphoglucomutase, ZINC ION 著者 Beamer, L.J. 登録日 2006-05-24 公開日 2006-08-08 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Complexes of the enzyme phosphomannomutase/phosphoglucomutase with a slow substrate and an inhibitor. Acta Crystallogr.,Sect.F, 62, 2006
2H4M	Karyopherin Beta2/Transportin-M9NLS 分子名称: Heterogeneous nuclear ribonucleoprotein A1, Transportin-1 著者 Chook, Y.M, Cansizoglu, A.E. 登録日 2006-05-24 公開日 2006-10-24 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (3.05 Å) 主引用文献 Rules for nuclear localization sequence recognition by karyopherin beta 2. Cell(Cambridge,Mass.), 126, 2006
2H4N	H94N CARBONIC ANHYDRASE II COMPLEXED WITH ACETAZOLAMIDE 分子名称: 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, CARBONIC ANHYDRASE II, ZINC ION 著者 Lesburg, C.A, Christianson, D.W. 登録日 1997-05-29 公開日 1997-09-17 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Histidine --> carboxamide ligand substitutions in the zinc binding site of carbonic anhydrase II alter metal coordination geometry but retain catalytic activity. Biochemistry, 36, 1997
2H4O	X-ray Crystal Structure of Protein yonK from Bacillus subtilis. Northeast Structural Genomics Consortium Target SR415 分子名称: YonK protein 著者 Seetharaman, J, Sue, M, Forouhar, F, Ken, C, Bonnie, C, Ma, L, Xiao, R, Acton, T.B, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) 登録日 2006-05-24 公開日 2006-07-25 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structure of the hypothetical protein from bacillus subtilis (yonk). To be Published
2H4P	Crystal structure of wildtype MENT in the cleaved conformation 分子名称: Heterochromatin-associated protein MENT 著者 Buckle, A.M, McGowan, S, Irving, J.A, Whisstock, J.C. 登録日 2006-05-24 公開日 2006-07-18 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 X-ray crystal structure of MENT: evidence for functional loop-sheet polymers in chromatin condensation. Embo J., 25, 2006
2H4Q	Crystal structure of a M-loop deletion variant of MENT in the cleaved conformation 分子名称: Heterochromatin-associated protein MENT 著者 Whisstock, J.C, Buckle, A.M, McGowan, S, Irving, J.A. 登録日 2006-05-25 公開日 2006-07-18 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 X-ray crystal structure of MENT: evidence for functional loop-sheet polymers in chromatin condensation. Embo J., 25, 2006
2H4R	Crystal structure of wildtype MENT in the native conformation 分子名称: Heterochromatin-associated protein MENT 著者 Irving, J.A, Whisstock, J.C, Buckle, A.M, McGowan, S. 登録日 2006-05-25 公開日 2006-07-18 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 X-ray crystal structure of MENT: evidence for functional loop-sheet polymers in chromatin condensation. Embo J., 25, 2006
2H4T	Crystal structure of rat carnitine palmitoyltransferase II 分子名称: Carnitine O-palmitoyltransferase II, mitochondrial, DODECANE 著者 Hsiao, Y.S, Jogl, G, Esser, V, Tong, L. 登録日 2006-05-25 公開日 2006-07-25 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of rat carnitine palmitoyltransferase II (CPT-II). Biochem.Biophys.Res.Commun., 346, 2006
2H4U	Crystal Structure of Human Thioesterase Superfamily Member 2 分子名称: Thioesterase superfamily member 2 著者 Ogg, D.J, Uppenberg, J, Arrowsmith, C, Berglund, H, Edwards, A, Ehn, M, Grasslund, S, Flodin, S, Hammerstrom, M, Hogbom, M, Holmberg-Schiavone, L, Kotenyova, T, Nilsson-Ehle, P, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Sundstrom, M, Thorsell, A.-G, Weigelt, J, Hallberg, M, Structural Genomics Consortium (SGC) 登録日 2006-05-25 公開日 2006-06-20 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The crystal structure of human thioesterase superfamily member 2 To be Published
2H4V	Crystal Structure of the Human Tyrosine Receptor Phosphatase Gamma 分子名称: 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ... 著者 Ugochukwu, E, Barr, A, Das, S, Eswaran, J, Savitsky, P, Sundstrom, M, Edwards, A, Arrowsmith, C, Weigelt, J, Debreczeni, J, von Delft, F, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2006-05-25 公開日 2006-07-11 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Large-scale structural analysis of the classical human protein tyrosine phosphatome. Cell(Cambridge,Mass.), 136, 2009
2H4W	Crystal structure of human caspase-1 (Glu390->Asp) in complex with 3-[2-(2-benzyloxycarbonylamino-3-methyl-butyrylamino)-propionylamino]-4-oxo-pentanoic acid (z-VAD-FMK) 分子名称: Caspase-1, N-[(benzyloxy)carbonyl]-L-valyl-N-[(2S)-1-carboxy-4-fluoro-3-oxobutan-2-yl]-L-alaninamide 著者 Scheer, J.M, Wells, J.A, Romanowski, M.J. 登録日 2006-05-25 公開日 2008-03-11 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 An allosteric circuit in caspase-1. J.Mol.Biol., 381, 2008
2H4X	Human bisphosphoglycerate mutase complex with 3-phosphoglycerate with crystal growth 90 days 分子名称: 3-PHOSPHOGLYCERIC ACID, Bisphosphoglycerate mutase 著者 Wang, Y, Gong, W. 登録日 2006-05-25 公開日 2006-10-24 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Seeing the process of histidine phosphorylation in human bisphosphoglycerate mutase. J.Biol.Chem., 281, 2006
2H4Y	Crystal structure of human caspase-1 (Arg286->Lys) in complex with 3-[2-(2-benzyloxycarbonylamino-3-methyl-butyrylamino)-propionylamino]-4-oxo-pentanoic acid (z-VAD-FMK) 分子名称: Caspase-1, N-[(benzyloxy)carbonyl]-L-valyl-N-[(2S)-1-carboxy-4-fluoro-3-oxobutan-2-yl]-L-alaninamide 著者 Scheer, J.M, Wells, J.A, Romanowski, M.J. 登録日 2006-05-25 公開日 2008-03-11 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 An allosteric circuit in caspase-1. J.Mol.Biol., 381, 2008
2H4Z	Human bisphosphoglycerate mutase complexed with 2,3-bisphosphoglycerate 分子名称: (2R)-2,3-diphosphoglyceric acid, Bisphosphoglycerate mutase 著者 Wang, Y, Gong, W. 登録日 2006-05-25 公開日 2006-10-24 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Seeing the process of histidine phosphorylation in human bisphosphoglycerate mutase. J.Biol.Chem., 281, 2006
2H50	Multiple distinct assemblies reveal conformational flexibility in the small heat shock protein Hsp26 分子名称: small heat shock protein Hsp26 著者 White, H.E, Orlova, E.V, Chen, S, Wang, L, Ignatiou, A, Gowen, B, Stromer, T, Franzmann, T.M, Haslbeck, M, Buchner, J, Saibil, H.R. 登録日 2006-05-25 公開日 2006-08-01 最終更新日 2024-02-14 実験手法 ELECTRON MICROSCOPY (10.8 Å) 主引用文献 Multiple distinct assemblies reveal conformational flexibility in the small heat shock protein hsp26 Structure, 14, 2006
2H51	Crystal structure of human caspase-1 (Glu390->Asp and Arg286->Lys) in complex with 3-[2-(2-benzyloxycarbonylamino-3-methyl-butyrylamino)-propionylamino]-4-oxo-pentanoic acid (z-VAD-FMK) 分子名称: Caspase-1, N-[(benzyloxy)carbonyl]-L-valyl-N-[(2S)-1-carboxy-4-fluoro-3-oxobutan-2-yl]-L-alaninamide 著者 Scheer, J.M, Wells, J.A, Romanowski, M.J. 登録日 2006-05-25 公開日 2008-03-11 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 An allosteric circuit in caspase-1. J.Mol.Biol., 381, 2008
2H52	Crystal structure of human bisphosphoglycerate mutase complex with 3-phosphoglycerate (18 days) 分子名称: 3-PHOSPHOGLYCERIC ACID, Bisphosphoglycerate mutase, CYCLOHEXYLAMMONIUM ION 著者 Wang, Y, Gong, W. 登録日 2006-05-25 公開日 2006-10-24 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Seeing the process of histidine phosphorylation in human bisphosphoglycerate mutase To be Published
2H53	Multiple distinct assemblies reveal conformational flexibility in the small heat shock protein Hsp26 分子名称: small heat shock protein Hsp26 著者 White, H.E, Orlova, E.V, Chen, S, Wang, L, Ignatiou, A, Gowen, B, Stromer, T, Franzmann, T.M, Haslbeck, M, Buchner, J, Saibil, H.R. 登録日 2006-05-25 公開日 2006-08-01 最終更新日 2024-02-14 実験手法 ELECTRON MICROSCOPY (11.5 Å) 主引用文献 Multiple distinct assemblies reveal conformational flexibility in the small heat shock protein hsp26 Structure, 14, 2006
2H54	Crystal structure of human caspase-1 (Thr388->Ala) in complex with 3-[2-(2-benzyloxycarbonylamino-3-methyl-butyrylamino)-propionylamino]-4-oxo-pentanoic acid (z-VAD-FMK) 分子名称: Caspase-1, N-[(benzyloxy)carbonyl]-L-valyl-N-[(2S)-1-carboxy-4-fluoro-3-oxobutan-2-yl]-L-alaninamide 著者 Scheer, J.M, Wells, J.A, Romanowski, M.J. 登録日 2006-05-25 公開日 2008-03-11 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 An allosteric circuit in caspase-1. J.Mol.Biol., 381, 2008
2H55	Structure of human Hsp90-alpha bound to the potent water soluble inhibitor PU-DZ8 分子名称: 2-FLUORO-8-[(6-IODO-1,3-BENZODIOXOL-5-YL)METHYL]-9-[3-(ISOPROPYLAMINO)PROPYL]-9H-PURIN-6-AMINE, Heat shock protein HSP 90-alpha 4 著者 Immormino, R.M, Gewirth, D.T. 登録日 2006-05-25 公開日 2006-10-03 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural and quantum chemical studies of 8-aryl-sulfanyl adenine class Hsp90 inhibitors. J.Med.Chem., 49, 2006

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