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8GTK
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BU of 8gtk by Molmil
Crystal structure of IpaH7.8-LRR and GSDMB isoform-1 complex
分子名称: GSDMB isoform-1, Probable E3 ubiquitin-protein ligase ipaH7.8
著者Zhong, X, Hou, Y.J, Ding, J.
登録日2022-09-08
公開日2023-04-12
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural mechanisms for regulation of GSDMB pore-forming activity.
Nature, 616, 2023
8GV8
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BU of 8gv8 by Molmil
The cryo-EM structure of hAE2 with DIDS
分子名称: 2,2'-ethane-1,2-diylbis{5-[(sulfanylmethyl)amino]benzenesulfonic acid}, Anion exchange protein 2
著者Zhang, Q, Jian, L, Yao, D, Rao, B, Hu, K, Xia, Y, Cao, Y.
登録日2022-09-14
公開日2023-04-12
実験手法ELECTRON MICROSCOPY (3.08 Å)
主引用文献The structural basis of the pH-homeostasis mediated by the Cl - /HCO 3 - exchanger, AE2.
Nat Commun, 14, 2023
8GTN
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BU of 8gtn by Molmil
Cryo-EM structure of the gasdermin B pore
分子名称: Isoform 4 of Gasdermin-B
著者Hou, Y.J, Cheng, H, Ding, J.
登録日2022-09-08
公開日2023-04-12
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.17 Å)
主引用文献Structural mechanisms for regulation of GSDMB pore-forming activity.
Nature, 616, 2023
8H02
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BU of 8h02 by Molmil
Crystal structure of Synechococcus elongatus PCC 7942 RNA polymerase SI3-tail
分子名称: DNA-directed RNA polymerase subunit beta'
著者Shen, L.Q, Zhang, Y.
登録日2022-09-27
公開日2023-04-19
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.552 Å)
主引用文献An SI3-sigma arch stabilizes cyanobacteria transcription initiation complex.
Proc.Natl.Acad.Sci.USA, 120, 2023
8GTJ
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BU of 8gtj by Molmil
Crystal structure of IpaH7.8-LRR and GSDMB isoform-4 complex
分子名称: Isoform 4 of Gasdermin-B, Probable E3 ubiquitin-protein ligase ipaH7.8
著者Zhong, X, Hou, Y.J, Ding, J.
登録日2022-09-08
公開日2023-04-12
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural mechanisms for regulation of GSDMB pore-forming activity.
Nature, 616, 2023
8GF1
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BU of 8gf1 by Molmil
Crystal structure of soluble lytic transglycosylase Cj0843 of Campylobacter jejuni in complex with LV8060 inhibitor
分子名称: CITRIC ACID, DIMETHYL SULFOXIDE, Lytic transglycosylase domain-containing protein, ...
著者van den Akker, F, Kumar, V.
登録日2023-03-07
公開日2023-05-24
最終更新日2023-07-05
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Exploring the inhibition of the soluble lytic transglycosylase Cj0843c of Campylobacter jejuni via targeting different sites with different scaffolds.
Protein Sci., 32, 2023
8GFG
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BU of 8gfg by Molmil
Crystal structure of soluble lytic transglycosylase Cj0843 of Campylobacter jejuni in complex with Z7912 inhibitor
分子名称: (3S,3aR,5S,6S,6aS)-2-oxohexahydro-2H-3,5-methanocyclopenta[b]furan-6-yl 2-acetamido-2-deoxy-beta-D-glucopyranoside, CITRIC ACID, DIMETHYL SULFOXIDE, ...
著者van den Akker, F, Kumar, V.
登録日2023-03-08
公開日2023-05-24
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Exploring the inhibition of the soluble lytic transglycosylase Cj0843c of Campylobacter jejuni via targeting different sites with different scaffolds.
Protein Sci., 32, 2023
8GFC
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BU of 8gfc by Molmil
Crystal structure of soluble lytic transglycosylase Cj0843 of Campylobacter jejuni in complex with Fv17b inhibitor
分子名称: CITRIC ACID, DIMETHYL SULFOXIDE, Lytic transglycosylase domain-containing protein, ...
著者van den Akker, F, Kumar, V.
登録日2023-03-08
公開日2023-05-24
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Exploring the inhibition of the soluble lytic transglycosylase Cj0843c of Campylobacter jejuni via targeting different sites with different scaffolds.
Protein Sci., 32, 2023
8GFH
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BU of 8gfh by Molmil
Crystal structure of soluble lytic transglycosylase Cj0843 of Campylobacter jejuni in complex with Z7285 inhibitor soaked at 10 mM concentration
分子名称: CITRIC ACID, Lytic transglycosylase domain-containing protein, [(2R)-5-oxopyrrolidin-2-yl]methyl 2-acetamido-2-deoxy-beta-D-glucopyranoside
著者van den Akker, F, Kumar, V.
登録日2023-03-08
公開日2023-05-24
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Exploring the inhibition of the soluble lytic transglycosylase Cj0843c of Campylobacter jejuni via targeting different sites with different scaffolds.
Protein Sci., 32, 2023
8GFF
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BU of 8gff by Molmil
Crystal structure of soluble lytic transglycosylase Cj0843 of Campylobacter jejuni in complex with Z7146 inhibitor
分子名称: CITRIC ACID, DIMETHYL SULFOXIDE, Lytic transglycosylase domain-containing protein, ...
著者van den Akker, F, Kumar, V.
登録日2023-03-08
公開日2023-05-24
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Exploring the inhibition of the soluble lytic transglycosylase Cj0843c of Campylobacter jejuni via targeting different sites with different scaffolds.
Protein Sci., 32, 2023
8GFE
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BU of 8gfe by Molmil
Crystal structure of soluble lytic transglycosylase Cj0843 of Campylobacter jejuni in complex with Z3261 inhibitor
分子名称: CITRIC ACID, DIMETHYL SULFOXIDE, Lytic transglycosylase domain-containing protein, ...
著者van den Akker, F, Kumar, V.
登録日2023-03-08
公開日2023-05-24
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献Exploring the inhibition of the soluble lytic transglycosylase Cj0843c of Campylobacter jejuni via targeting different sites with different scaffolds.
Protein Sci., 32, 2023
8GFJ
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BU of 8gfj by Molmil
Crystal structure of soluble lytic transglycosylase Cj0843 of Campylobacter jejuni dose-response soaking with 1 mM concentration Z7285 inhibitor (no inhibitor binding observed)
分子名称: CITRIC ACID, Lytic transglycosylase domain-containing protein
著者van den Akker, F, Kumar, V.
登録日2023-03-08
公開日2023-05-24
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Exploring the inhibition of the soluble lytic transglycosylase Cj0843c of Campylobacter jejuni via targeting different sites with different scaffolds.
Protein Sci., 32, 2023
6VYC
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BU of 6vyc by Molmil
Crystal structure of WD-repeat domain of human WDR91
分子名称: UNKNOWN ATOM OR ION, WD repeat-containing protein 91
著者Halabelian, L, Hutchinson, A, Li, Y, Seitova, A, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Structural Genomics Consortium (SGC)
登録日2020-02-26
公開日2020-03-25
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Discovery of a First-in-Class Small-Molecule Ligand for WDR91 Using DNA-Encoded Chemical Library Selection Followed by Machine Learning.
J.Med.Chem., 66, 2023
8GFM
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BU of 8gfm by Molmil
Crystal structure of soluble lytic transglycosylase Cj0843 of Campylobacter jejuni in complex with zanamivir amine inhibitor
分子名称: 4-AMINO-2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, CITRIC ACID, Lytic transglycosylase domain-containing protein
著者van den Akker, F, Kumar, V.
登録日2023-03-08
公開日2023-05-24
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Exploring the inhibition of the soluble lytic transglycosylase Cj0843c of Campylobacter jejuni via targeting different sites with different scaffolds.
Protein Sci., 32, 2023
8GFQ
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BU of 8gfq by Molmil
Crystal structure of soluble lytic transglycosylase Cj0843 of Campylobacter jejuni in complex with Fv32r inhibitor
分子名称: 9-AMINO-2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, CITRIC ACID, DIMETHYL SULFOXIDE, ...
著者van den Akker, F, Kumar, V.
登録日2023-03-08
公開日2023-05-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Exploring the inhibition of the soluble lytic transglycosylase Cj0843c of Campylobacter jejuni via targeting different sites with different scaffolds.
Protein Sci., 32, 2023
3K03
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BU of 3k03 by Molmil
Crystal Structure of CNG mimicking NaK mutant, NaK-DTPP, K+ complex
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, POTASSIUM ION, Potassium channel protein NaK
著者Jiang, Y, Derebe, M.G.
登録日2009-09-24
公開日2011-01-12
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Tuning the ion selectivity of tetrameric cation channels by changing the number of ion binding sites.
Proc.Natl.Acad.Sci.USA, 108, 2011
8GEZ
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BU of 8gez by Molmil
Crystal structure of soluble lytic transglycosylase Cj0843 of Campylobacter jejuni in complex with LV8036 inhibitor
分子名称: CITRIC ACID, DIMETHYL SULFOXIDE, Lytic transglycosylase domain-containing protein, ...
著者van den Akker, F, Kumar, V.
登録日2023-03-07
公開日2023-05-24
最終更新日2023-07-05
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Exploring the inhibition of the soluble lytic transglycosylase Cj0843c of Campylobacter jejuni via targeting different sites with different scaffolds.
Protein Sci., 32, 2023
8GF0
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BU of 8gf0 by Molmil
Crystal structure of soluble lytic transglycosylase Cj0843 of Campylobacter jejuni in complex with LV8044 inhibitor
分子名称: 2,2-dimethyl-3-oxobutyl 2-acetamido-2-deoxy-beta-D-glucopyranoside, CITRIC ACID, DIMETHYL SULFOXIDE, ...
著者van den Akker, F, Kumar, V.
登録日2023-03-07
公開日2023-05-24
最終更新日2023-07-05
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Exploring the inhibition of the soluble lytic transglycosylase Cj0843c of Campylobacter jejuni via targeting different sites with different scaffolds.
Protein Sci., 32, 2023
8GFP
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BU of 8gfp by Molmil
Crystal structure of soluble lytic transglycosylase Cj0843 of Campylobacter jejuni in complex with N-acetyl-2,3-dehydro-2-deoxyneuraminic acid inhibitor
分子名称: 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, CITRIC ACID, Lytic transglycosylase domain-containing protein, ...
著者van den Akker, F, Kumar, V.
登録日2023-03-08
公開日2023-05-24
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Exploring the inhibition of the soluble lytic transglycosylase Cj0843c of Campylobacter jejuni via targeting different sites with different scaffolds.
Protein Sci., 32, 2023
8GFS
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BU of 8gfs by Molmil
Crystal structure of soluble lytic transglycosylase Cj0843 of Campylobacter jejuni in complex with siastatin B inhibitor
分子名称: (2S,3R,4S,5S)-2-(acetylamino)-5-carboxy-3,4-dihydroxypiperidinium, CITRIC ACID, Lytic transglycosylase domain-containing protein
著者van den Akker, F, Kumar, V.
登録日2023-03-08
公開日2023-05-24
最終更新日2023-07-05
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Exploring the inhibition of the soluble lytic transglycosylase Cj0843c of Campylobacter jejuni via targeting different sites with different scaffolds.
Protein Sci., 32, 2023
8GFD
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BU of 8gfd by Molmil
Crystal structure of soluble lytic transglycosylase Cj0843 of Campylobacter jejuni in complex with Z3252 inhibitor
分子名称: 2-(1-benzofuran-5-yl)ethyl 2-acetamido-2-deoxy-beta-D-glucopyranoside, CITRIC ACID, DIMETHYL SULFOXIDE, ...
著者van den Akker, F, Kumar, V.
登録日2023-03-08
公開日2023-05-24
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Exploring the inhibition of the soluble lytic transglycosylase Cj0843c of Campylobacter jejuni via targeting different sites with different scaffolds.
Protein Sci., 32, 2023
8GFI
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BU of 8gfi by Molmil
Crystal structure of soluble lytic transglycosylase Cj0843 of Campylobacter jejuni in complex with Z7285 inhibitor soaked at 3 mM concentration
分子名称: CITRIC ACID, Lytic transglycosylase domain-containing protein, [(2R)-5-oxopyrrolidin-2-yl]methyl 2-acetamido-2-deoxy-beta-D-glucopyranoside
著者van den Akker, F, Kumar, V.
登録日2023-03-08
公開日2023-05-24
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Exploring the inhibition of the soluble lytic transglycosylase Cj0843c of Campylobacter jejuni via targeting different sites with different scaffolds.
Protein Sci., 32, 2023
8GFB
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BU of 8gfb by Molmil
Crystal structure of soluble lytic transglycosylase Cj0843 of Campylobacter jejuni in complex with Fv16b inhibitor
分子名称: CITRIC ACID, DIMETHYL SULFOXIDE, Lytic transglycosylase domain-containing protein, ...
著者van den Akker, F, Kumar, V.
登録日2023-03-08
公開日2023-05-24
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Exploring the inhibition of the soluble lytic transglycosylase Cj0843c of Campylobacter jejuni via targeting different sites with different scaffolds.
Protein Sci., 32, 2023
3K45
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BU of 3k45 by Molmil
Alternate Binding Modes Observed for the E- and Z-isomers of 2,4-Diaminofuro[2,3d]pyrimidines as Ternary Complexes with NADPH and Mouse Dihydrofolate Reductase
分子名称: 5-[(1Z)-2-(2-methoxyphenyl)prop-1-en-1-yl]furo[2,3-d]pyrimidine-2,4-diamine, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Cody, V.
登録日2009-10-05
公開日2009-10-13
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Design, synthesis, and X-ray crystal structures of 2,4-diaminofuro[2,3-d]pyrimidines as multireceptor tyrosine kinase and dihydrofolate reductase inhibitors.
Bioorg.Med.Chem., 17, 2009
3JQZ
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BU of 3jqz by Molmil
Crystal Structure of Human serum albumin complexed with Lidocaine
分子名称: 2-(diethylamino)-N-(2,6-dimethylphenyl)ethanamide, Serum albumin
著者Hein, K.L, Kragh-Hansen, U, Morth, J.P, Nissen, P.
登録日2009-09-08
公開日2010-04-21
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Crystallographic analysis reveals a unique lidocaine binding site on human serum albumin.
J.Struct.Biol., 2010

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件を2024-07-10に公開中

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