PDB: 45853 件ウェブページステータス検索Chemie searchBIRD

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8RFZ	Structure of E166A BlaC from Mycobacterium tuberculosis at pH 4.5 分子名称: Beta-lactamase, SULFATE ION 著者 Sun, J, Bruenle, S, Ubbink, M. 登録日 2023-12-13 公開日 2024-08-28 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 A low-barrier proton shared between two aspartates acts as a conformational switch that changes the substrate specificity of the beta-lactamase BlaC. Int.J.Biol.Macromol., 278, 2024
6OVX	Crystal structure of mithramycin 3-side chain keto-reductase MtmW in complex with NAD+, P422 form 分子名称: GLYCEROL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Putative side chain reductase 著者 Hou, C, Yu, X, Rohr, J, Tsodikov, O.V. 登録日 2019-05-08 公開日 2019-11-27 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Discovery of a Cryptic Intermediate in Late Steps of Mithramycin Biosynthesis. Angew.Chem.Int.Ed.Engl., 59, 2020
6WKL	Fab Fragment of Anti-human LAG3 antibody (BAP050) 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BAP050 Fab Heavy Chain, BAP050 Fab Light Chain 著者 Agnihotri, P, Mishra, A.K, Mariuzza, R.A. 登録日 2020-04-16 公開日 2021-04-21 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Fab Fragment of Anti-human LAG3 antibody To Be Published
6OR0	Crystal structure of Insulin from Non-merohedrally twinned crystals 分子名称: Insulin chain A, Insulin chain B 著者 Sevvana, M, Ruf, M, Uson, I, Sheldrick, G.M, Herbst-Irmer, R. 登録日 2019-04-29 公開日 2019-12-11 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Non-merohedral twinning: from minerals to proteins. Acta Crystallogr D Struct Biol, 75, 2019
6WEO	IL-22 Signaling Complex with IL-22R1 and IL-10Rbeta 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Saxton, R.A, Jude, K.M, Henneberg, L.T, Garcia, K.C. 登録日 2020-04-02 公開日 2021-04-28 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 The tissue protective functions of interleukin-22 can be decoupled from pro-inflammatory actions through structure-based design. Immunity, 54, 2021
6M0E	Beijerinckia indica beta-fructosyltransferase complexed with fructose 分子名称: Levansucrase, MAGNESIUM ION, beta-D-fructofuranose, ... 著者 Tonozuka, T. 登録日 2020-02-21 公開日 2020-08-12 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Crystal structure of a glycoside hydrolase family 68 beta-fructosyltransferase from Beijerinckia indica subsp. indica in complex with fructose. Biosci.Biotechnol.Biochem., 84, 2020
7QGJ	Apo structure of BIR2 Domain of BIRC2 分子名称: 1,2-ETHANEDIOL, Baculoviral IAP repeat-containing protein 2, ZINC ION 著者 Kraemer, A, Farges, F, Schwalm, M.P, Saxena, K, Preuss, F, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2021-12-08 公開日 2022-02-09 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Apo structure BIR2 Domain of BIRC2 To Be Published
6O6S	Crystal structure of Apo Csm6 分子名称: Csm6 著者 Jia, N, Patel, D.J. 登録日 2019-03-07 公開日 2019-07-31 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 CRISPR-Cas III-A Csm6 CARF Domain Is a Ring Nuclease Triggering Stepwise cA4Cleavage with ApA>p Formation Terminating RNase Activity. Mol.Cell, 75, 2019
6ZZH	Structure of soluble SmhB crystal form 2 of the tripartite alpha-pore forming toxin, Smh, from Serratia marcescens. 分子名称: SmhB 著者 Churchill-Angus, A.M, Baker, P.J. 登録日 2020-08-04 公開日 2021-03-31 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Characterisation of a tripartite alpha-pore forming toxin from Serratia marcescens Sci Rep, 11, 2021
6M7A	Structure of REV7-R124A complexed with SHLD3(28-73) 分子名称: Mitotic spindle assembly checkpoint protein MAD2B, Shieldin complex subunit 3 著者 Ma, Y.Z, Li, Y, Wu, B.X, Huang, H.D. 登録日 2020-03-18 公開日 2021-01-27 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure of REV7-R124A complexed with SHLD3(28-73) To Be Published
6ZSY	Crystal structure of the Grindelwald extracellular domain complex 分子名称: Protein grindelwald 著者 Palmerini, V, Cecatiello, V, Pasqualato, S, Mapelli, M. 登録日 2020-07-17 公開日 2021-03-31 最終更新日 2021-10-13 実験手法 X-RAY DIFFRACTION (0.926 Å) 主引用文献 Drosophila TNFRs Grindelwald and Wengen bind Eiger with different affinities and promote distinct cellular functions. Nat Commun, 12, 2021
6OEW	Structure of a Cytidylyltransferase from Leptospira borgpetersenii serovar Hardjo-bovis (strain JB197) 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Cytidylyltransferase, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2019-03-27 公開日 2019-04-17 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structure of a Cytidylyltransferase from Leptospira borgpetersenii serovar Hardjo-bovis (strain JB197) to be published
8ROI	Human cohesin SMC3-HD(EQ)/RAD21-N complex - ADP-bound conformation 分子名称: ADENOSINE-5'-DIPHOSPHATE, Double-strand-break repair protein rad21 homolog, Structural maintenance of chromosomes protein 3 著者 Vitoria Gomes, M, Romier, C. 登録日 2024-01-11 公開日 2024-09-11 最終更新日 2024-09-25 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 The cohesin ATPase cycle is mediated by specific conformational dynamics and interface plasticity of SMC1A and SMC3 ATPase domains. Cell Rep, 43, 2024
7A9W	Structure of yeast Rmd9p in complex with 20nt target RNA 分子名称: CHLORIDE ION, Protein RMD9, mitochondrial, ... 著者 Hillen, H.S, Markov, D.A, Ireneusz, W.D, Hofmann, K.B, Cowan, A.T, Jones, J.L, Temiakov, D, Cramer, P, Anikin, M. 登録日 2020-09-02 公開日 2021-04-07 最終更新日 2021-05-05 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 The pentatricopeptide repeat protein Rmd9 recognizes the dodecameric element in the 3'-UTRs of yeast mitochondrial mRNAs. Proc.Natl.Acad.Sci.USA, 118, 2021
6OHY	Chimpanzee SIV Env trimeric ectodomain. 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Pallesen, J, Andrabi, R, de Val, N, Burton, D.R, Ward, A.B. 登録日 2019-04-08 公開日 2019-06-05 最終更新日 2024-10-09 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 The Chimpanzee SIV Envelope Trimer: Structure and Deployment as an HIV Vaccine Template. Cell Rep, 27, 2019
6ZMD	Crystal structure of HYPE covalently tethered to BiP bound to AMP-PNP 分子名称: Endoplasmic reticulum chaperone BiP, MAGNESIUM ION, PHOSPHATE ION, ... 著者 Fauser, J, Gulen, B, Pett, C, Hedberg, C, Itzen, A, Pogenberg, V. 登録日 2020-07-02 公開日 2021-04-14 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.64 Å) 主引用文献 Specificity of AMPylation of the human chaperone BiP is mediated by TPR motifs of FICD. Nat Commun, 12, 2021
6OIP	Crystal structure of MYST acetyltransferase domain in complex with inhibitor 34 分子名称: 2-fluoro-3-methyl-N'-[(naphthalen-2-yl)sulfonyl]benzohydrazide, GLYCEROL, Histone acetyltransferase KAT8, ... 著者 Hermans, S.J, Chung, M.C, Parker, M.W, Thomas, T, Baell, J.B. 登録日 2019-04-09 公開日 2019-07-03 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Discovery of Benzoylsulfonohydrazides as Potent Inhibitors of the Histone Acetyltransferase KAT6A. J.Med.Chem., 62, 2019
7A9X	Structure of yeast Rmd9p in complex with 16nt target RNA 分子名称: CHLORIDE ION, Protein RMD9, mitochondrial, ... 著者 Hillen, H.S, Markov, D.A, Ireneusz, W.D, Hofmann, K.B, Cowan, A.T, Jones, J.L, Temiakov, D, Cramer, P, Anikin, M. 登録日 2020-09-02 公開日 2021-04-07 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 The pentatricopeptide repeat protein Rmd9 recognizes the dodecameric element in the 3'-UTRs of yeast mitochondrial mRNAs. Proc.Natl.Acad.Sci.USA, 118, 2021
7A10	LppS with covalent adduct derived from 1g 分子名称: 4-methoxycyclohexa-2,5-diene-1-thione, L,D-transpeptidase 2 著者 Schnell, R, Steiner, E.M. 登録日 2020-08-11 公開日 2021-04-21 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 N-Thio-beta-lactams targeting L,D-transpeptidase-2, with activity against drug-resistant strains of Mycobacterium tuberculosis. Cell Chem Biol, 28, 2021
6OJM	Crystal structure of 1,4-dihydroxy-2-naphthoyl-CoA synthase Elizabethkingia anophelis NUHP1 分子名称: 1,4-dihydroxy-2-naphthoyl-CoA synthase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2019-04-11 公開日 2019-05-08 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structure of 1,4-dihydroxy-2-naphthoyl-CoA synthase Elizabethkingia anophelis NUHP1 TO BE PUBLISHED
6ZM2	Crystal structure of the DEAH-box ATPase Prp2 in complex with ADP-BeF3 and ssRNA 分子名称: 1,2-ETHANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, ADENOSINE-5'-DIPHOSPHATE, ... 著者 Hamann, F, Ficner, R. 登録日 2020-07-01 公開日 2021-04-21 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The structure of Prp2 bound to RNA and ADP-BeF 3 - reveals structural features important for RNA unwinding by DEAH-box ATPases. Acta Crystallogr D Struct Biol, 77, 2021
8EZD	Brain-derived 42-residue amyloid-beta fibril type A 分子名称: Beta-amyloid protein 42 著者 Tycko, R, Lee, M, Yau, Y.-M, Louis, J.M. 登録日 2022-10-31 公開日 2023-03-22 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (2.83 Å) 主引用文献 Structures of brain-derived 42-residue amyloid-beta fibril polymorphs with unusual molecular conformations and intermolecular interactions. Proc.Natl.Acad.Sci.USA, 120, 2023
8EZE	Brain-derived 42-residue amyloid-beta fibril type B 分子名称: Beta-amyloid protein 42 著者 Tycko, R, Lee, M, Yau, Y.-M, Louis, J.M. 登録日 2022-10-31 公開日 2023-03-22 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (2.76 Å) 主引用文献 Structures of brain-derived 42-residue amyloid-beta fibril polymorphs with unusual molecular conformations and intermolecular interactions. Proc.Natl.Acad.Sci.USA, 120, 2023
7A0Z	LppS with covalent adduct derived from 1b 分子名称: L,D-transpeptidase 2, TRIS(HYDROXYETHYL)AMINOMETHANE, benzenethiol 著者 Schnell, R, Steiner, E.M. 登録日 2020-08-11 公開日 2021-04-21 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 N-Thio-beta-lactams targeting L,D-transpeptidase-2, with activity against drug-resistant strains of Mycobacterium tuberculosis. Cell Chem Biol, 28, 2021
8S4H	Crystal structure of scFv-1B6 in complex with rocuronium bromide 分子名称: ScFv-1B6 VL, rocuronium, scFv-1B6 VH 著者 Saul, F.A, Haouz, A, Bruhns, P. 登録日 2024-02-21 公開日 2024-09-18 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Rocuronium-specific antibodies drive perioperative anaphylaxis but can also function as reversal agents in preclinical models. Sci Transl Med, 16, 2024

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