8EZE
Brain-derived 42-residue amyloid-beta fibril type B
Summary for 8EZE
| Entry DOI | 10.2210/pdb8eze/pdb |
| EMDB information | 28740 28741 |
| Descriptor | Beta-amyloid protein 42 (1 entity in total) |
| Functional Keywords | amyloid-b 42 (ab42) fibril, alzheimer's disease (ad), polymorphism., protein fibril |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 8 |
| Total formula weight | 36160.70 |
| Authors | Tycko, R.,Lee, M.,Yau, Y.-M.,Louis, J.M. (deposition date: 2022-10-31, release date: 2023-03-22, Last modification date: 2024-06-19) |
| Primary citation | Lee, M.,Yau, W.M.,Louis, J.M.,Tycko, R. Structures of brain-derived 42-residue amyloid-beta fibril polymorphs with unusual molecular conformations and intermolecular interactions. Proc.Natl.Acad.Sci.USA, 120:e2218831120-e2218831120, 2023 Cited by PubMed: 36893281DOI: 10.1073/pnas.2218831120 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (2.76 Å) |
Structure validation
Download full validation report
