PDB: 45459 件ウェブページステータス検索Chemie searchBIRD

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7QZ2	Crystal structure of GacS D1 domain in complex with BeF3- 分子名称: BERYLLIUM TRIFLUORIDE ION, CADMIUM ION, Histidine kinase, ... 著者 Fadel, F, Bassim, V, Botzanowski, T, Francis, V.I, Legrand, P, Porter, S.L, Bourne, Y, Cianferani, S, Vincent, F. 登録日 2022-01-30 公開日 2022-07-06 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Insights into the atypical autokinase activity of the Pseudomonas aeruginosa GacS histidine kinase and its interaction with RetS. Structure, 30, 2022
5DRY	Crystal structure of Dot1L in complex with inhibitor CPD3 [N-(1-(2-chlorophenyl)-1H-indol-6-yl)-2-(2-(5-(2-chlorophenyl)-1H-tetrazol-1-yl)acetyl)hydrazinecarboxamide] 分子名称: Histone-lysine N-methyltransferase, H3 lysine-79 specific, N-[1-(2-chlorophenyl)-1H-indol-6-yl]-2-{[5-(2-chlorophenyl)-1H-tetrazol-1-yl]acetyl}hydrazinecarboxamide, ... 著者 Scheufler, C, Gaul, C, Be, C, Moebitz, H. 登録日 2015-09-16 公開日 2016-06-15 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.41 Å) 主引用文献 Discovery of Novel Dot1L Inhibitors through a Structure-Based Fragmentation Approach. Acs Med.Chem.Lett., 7, 2016
6NV2	14-3-3 sigma with RelA/p65 binding site pS45 in complex with DP005 分子名称: (4R,5R,6R,6aS,9S,9aE,10aR)-5-hydroxy-9-(methoxymethyl)-6,10a-dimethyl-3-(propan-2-yl)-1,2,4,5,6,6a,7,8,9,10a-decahydrodicyclopenta[a,d][8]annulen-4-yl alpha-D-glucopyranoside, 14-3-3 protein sigma, CHLORIDE ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2019-02-04 公開日 2020-05-13 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.13 Å) 主引用文献 Selectivity via Cooperativity: Preferential Stabilization of the p65/14-3-3 Interaction with Semisynthetic Natural Products. J.Am.Chem.Soc., 142, 2020
5DTM	Crystal structure of Dot1L in complex with inhibitor CPD1 [4-(2,6-dichlorobenzoyl)-N-methyl-1H-pyrrole-2-carboxamide] 分子名称: 4-(2,6-dichlorobenzoyl)-N-methyl-1H-pyrrole-2-carboxamide, Histone-lysine N-methyltransferase, H3 lysine-79 specific 著者 Scheufler, C, Be, C, Moebitz, H, Stauffer, F. 登録日 2015-09-18 公開日 2016-06-15 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Optimization of a Fragment-Based Screening Hit toward Potent DOT1L Inhibitors Interacting in an Induced Binding Pocket. Acs Med.Chem.Lett., 7, 2016
6NCS	Crystal structure of N-acetylneuraminic acid (Sialic acid) synthetase from Leptospira borgpetersenii serovar Hardjo-bovis in complex with citrate 分子名称: ACETATE ION, CITRIC ACID, D(-)-TARTARIC ACID, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2018-12-12 公開日 2018-12-26 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of N-acetylneuraminic acid (Sialic acid) synthetase from Leptospira borgpetersenii serovar Hardjo-bovis in complex with citrate to be published
7R57	Escherichia coli type II Asparaginase N24S mutant in its apo form 分子名称: L-asparaginase 2 著者 Maggi, M, Scotti, C. 登録日 2022-02-10 公開日 2022-09-14 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Structural Aspects of E. coli Type II Asparaginase in Complex with Its Secondary Product L-Glutamate. Int J Mol Sci, 23, 2022
5DY1	Crystal of Selenomethionine substituted AmtR from Corynebacterium glutamicum 分子名称: CALCIUM ION, TetR family transcriptional regulator 著者 Palanca, C, Rubio, V. 登録日 2015-09-24 公開日 2016-01-13 最終更新日 2016-03-30 実験手法 X-RAY DIFFRACTION (2.651 Å) 主引用文献 Structure of AmtR, the global nitrogen regulator of Corynebacterium glutamicum, in free and DNA-bound forms. Febs J., 283, 2016
5E0K	X-ray crystal structure of tryptophan synthase complex from Pyrococcus furiosus at 2.76 A 分子名称: PHOSPHATE ION, Tryptophan synthase alpha chain, Tryptophan synthase beta chain 1 著者 Buller, A.R, Murciano-Calles, J, Arnold, F.H. 登録日 2015-09-29 公開日 2015-11-11 最終更新日 2019-12-25 実験手法 X-RAY DIFFRACTION (2.76 Å) 主引用文献 Directed evolution of the tryptophan synthase beta-subunit for stand-alone function recapitulates allosteric activation. Proc.Natl.Acad.Sci.USA, 112, 2015
5E2R	The crystal structure of the human carbonic anhydrase II in complex with a 1,1'-biphenyl-4-sulfonamide inhibitor 分子名称: 4'-(4-aminobenzoyl)biphenyl-4-sulfonamide, Carbonic anhydrase 2, GLYCEROL, ... 著者 Alterio, V, De Simone, G. 登録日 2015-10-01 公開日 2015-11-04 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Discovery of 1,1'-Biphenyl-4-sulfonamides as a New Class of Potent and Selective Carbonic Anhydrase XIV Inhibitors. J.Med.Chem., 58, 2015
6NTC	Crystal Structure of G12V HRas-GppNHp bound in complex with the engineered RBD variant 1 of CRAF Kinase protein 分子名称: GLYCEROL, GTPase HRas, MAGNESIUM ION, ... 著者 Maisonneuve, P, Kurinov, I, Wiechmann, S, Ernst, A, Sicheri, F. 登録日 2019-01-28 公開日 2020-03-04 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Conformation-specific inhibitors of activated Ras GTPases reveal limited Ras dependency of patient-derived cancer organoids. J.Biol.Chem., 295, 2020
5EC1	KcsA with V76ester mutation 分子名称: Antibody Fab Fragment Light Chain, DIACYL GLYCEROL, NONAN-1-OL, ... 著者 Matulef, K, Valiyaveetil, F.I. 登録日 2015-10-20 公開日 2016-04-20 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Individual Ion Binding Sites in the K(+) Channel Play Distinct Roles in C-type Inactivation and in Recovery from Inactivation. Structure, 24, 2016
5DWC	Crystal structure of restriction endonuclease AgeI 分子名称: Type-2 restriction enzyme AgeI 著者 Tamulaitiene, G, Ramonaite, I, Grazulis, S, Siksnys, V. 登録日 2015-09-22 公開日 2016-09-28 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Restriction endonuclease AgeI is a monomer which dimerizes to cleave DNA. Nucleic Acids Res., 45, 2017
5EBL	KcsA T75G in the Conductive State 分子名称: Antibody Fab Fragment Light Chain, DIACYL GLYCEROL, NONAN-1-OL, ... 著者 Matulef, K, Valiyaveetil, F.I. 登録日 2015-10-19 公開日 2016-04-20 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Individual Ion Binding Sites in the K(+) Channel Play Distinct Roles in C-type Inactivation and in Recovery from Inactivation. Structure, 24, 2016
6NPH	Structure of NKCC1 TM domain 分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CHLORIDE ION, POTASSIUM ION, ... 著者 Feng, L, Liao, M.F, Orlando, B, Zhang, J.R. 登録日 2019-01-17 公開日 2019-07-31 最終更新日 2020-01-29 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structure and mechanism of the cation-chloride cotransporter NKCC1. Nature, 572, 2019
5E26	Crystal structure of human PANK2: the catalytic core domain in complex with pantothenate and adenosine diphosphate 分子名称: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, GLYCEROL, ... 著者 DONG, A, LOPPNAU, P, RAVICHANDRAN, M, CHENG, C, TEMPEL, W, SEITOVA, A, HUTCHINSON, A, HONG, B.S, Bountra, C, Arrowsmith, C.H, Edwards, A.M, BROWN, P.J, Structural Genomics Consortium (SGC) 登録日 2015-09-30 公開日 2015-10-21 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Crystal structure of human PANK2: the catalytic core domain in complex with pantothenate and adenosine diphosphate to be published
5E2W	Anti-TAU AT8 FAB with triply phosphorylated TAU peptide 分子名称: AT8 HEAVY CHAIN, AT8 LIGHT CHAIN, TAU-PHOSPHOPEPTIDE 著者 Malia, T, Teplyakov, A. 登録日 2015-10-01 公開日 2016-02-24 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Epitope mapping and structural basis for the recognition of phosphorylated tau by the anti-tau antibody AT8. Proteins, 84, 2016
6NTV	SFTSV L endonuclease domain 分子名称: RNA polymerase 著者 Wang, W, Amarasinghe, G.K. 登録日 2019-01-30 公開日 2020-01-08 最終更新日 2020-07-22 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 The Cap-Snatching SFTSV Endonuclease Domain Is an Antiviral Target. Cell Rep, 30, 2020
6OPQ	CD4- and 17-bound HIV-1 Env B41 SOSIP frozen with LMNG 分子名称: 17b Fab heavy chain, 17b Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Ozorowski, G, Torres, J.L, Ward, A.B. 登録日 2019-04-25 公開日 2020-10-21 最終更新日 2020-12-09 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 A Strain-Specific Inhibitor of Receptor-Bound HIV-1 Targets a Pocket near the Fusion Peptide. Cell Rep, 33, 2020
6O8S	Syn-safencin 56 分子名称: Circular bacteriocin, circularin A/uberolysin family 著者 Fields, F.R, Lee, S.W. 登録日 2019-03-11 公開日 2020-05-13 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Synthetic Antimicrobial Peptide Tuning Permits Membrane Disruption and Interpeptide Synergy. Acs Pharmacol Transl Sci, 3, 2020
6OS6	Crystal structure of CymD prenyltransferase complexed with L-tryptophan and DMSPP 分子名称: BENZOIC ACID, CHLORIDE ION, CymD prenyltransferase, ... 著者 Roose, B.W, Christianson, D.W. 登録日 2019-05-01 公開日 2019-07-17 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.33 Å) 主引用文献 Structural Basis of Tryptophan Reverse N-Prenylation Catalyzed by CymD. Biochemistry, 58, 2019
5DO6	Crystal structure of Dendroaspis polylepis venom mambalgin-1 T23A mutant 分子名称: 1,2-ETHANEDIOL, IODIDE ION, Mambalgin-1, ... 著者 Stura, E.A, Tepshi, L, Kessler, P, Gilles, M, Servent, D. 登録日 2015-09-10 公開日 2015-12-30 最終更新日 2017-01-25 実験手法 X-RAY DIFFRACTION (1.697 Å) 主引用文献 Mambalgin-1 Pain-relieving Peptide, Stepwise Solid-phase Synthesis, Crystal Structure, and Functional Domain for Acid-sensing Ion Channel 1a Inhibition. J.Biol.Chem., 291, 2016
5DUX	Crystal structure of the human galectin-4 N-terminal carbohydrate recognition domain in complex with 2'-fucosyllactose 分子名称: FORMIC ACID, GLYCEROL, Galectin-4, ... 著者 Bum-Erdene, K, Blanchard, H. 登録日 2015-09-21 公開日 2016-02-17 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structural characterisation of human galectin-4 N-terminal carbohydrate recognition domain in complex with glycerol, lactose, 3'-sulfo-lactose, and 2'-fucosyllactose. Sci Rep, 6, 2016
8OOX	Glutamine synthetase from Methermicoccus shengliensis at a resolution of 3.09 A 分子名称: CITRIC ACID, GLYCEROL, Glutamine synthetase, ... 著者 Mueller, M.-C, Lemaire, O.N, Wagner, T. 登録日 2023-04-06 公開日 2024-01-24 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.09 Å) 主引用文献 Differences in regulation mechanisms of glutamine synthetases from methanogenic archaea unveiled by structural investigations. Commun Biol, 7, 2024
8OXN	CRYSTAL STRUCTURE OF THE COFACTOR-DEVOID 1-H-3-HYDROXY-4- OXOQUINALDINE 2,4-DIOXYGENASE (HOD) S101A VARIANT COMPLEXED WITH 2-METHYL-QUINOLIN-4(1H)-ONE UNDER NORMOXYC CONDITIONS 分子名称: 1H-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase, 2-methyl-quinolin-4(1H)-one, GLYCEROL, ... 著者 Bui, S, Steiner, R.A. 登録日 2023-05-02 公開日 2024-01-17 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Evolutionary adaptation from hydrolytic to oxygenolytic catalysis at the alpha / beta-hydrolase fold. Chem Sci, 14, 2023
8OXT	CRYSTAL STRUCTURE OF THE COFACTOR-DEVOID 1-H-3-HYDROXY-4- OXOQUINALDINE 2,4-DIOXYGENASE (HOD) H251A VARIANT COMPLEXED WITH N-ACETYLANTHRANILATE AS RESULT OF IN CRYSTALLO TURNOVER OF ITS NATURAL SUBSTRATE 1-H-3-HYDROXY-4- OXOQUINALDINE UNDER HYPEROXIC CONDITIONS 分子名称: 1H-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase, 2-(ACETYLAMINO)BENZOIC ACID, GLYCEROL, ... 著者 Bui, S, Steiner, R.A. 登録日 2023-05-02 公開日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.003 Å) 主引用文献 Evolutionary adaptation from hydrolytic to oxygenolytic catalysis at the alpha / beta-hydrolase fold. Chem Sci, 14, 2023

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