5DO6

Crystal structure of Dendroaspis polylepis venom mambalgin-1 T23A mutant

Summary for 5DO6

Entry DOI	10.2210/pdb5do6/pdb
Related	2MFA 2MJY
Descriptor	Mambalgin-1, IODIDE ION, 1,2-ETHANEDIOL, ... (5 entities in total)
Functional Keywords	toxin, acid sensing ion channels, pain suppression drug, elapid venom polypeptide
Biological source	Dendroaspis polylepis polylepis (Black mamba)
Cellular location	Secreted : P0DKR6
Total number of polymer chains	2
Total formula weight	13861.92
Authors	Stura, E.A.,Tepshi, L.,Kessler, P.,Gilles, M.,Servent, D. (deposition date: 2015-09-10, release date: 2015-12-30, Last modification date: 2017-01-25)
Primary citation	Mourier, G.,Salinas, M.,Kessler, P.,Stura, E.A.,Leblanc, M.,Tepshi, L.,Besson, T.,Diochot, S.,Baron, A.,Douguet, D.,Lingueglia, E.,Servent, D. Mambalgin-1 Pain-relieving Peptide, Stepwise Solid-phase Synthesis, Crystal Structure, and Functional Domain for Acid-sensing Ion Channel 1a Inhibition. J.Biol.Chem., 291:2616-2629, 2016 Cited by PubMed: 26680001 DOI: 10.1074/jbc.M115.702373 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.697 Å)

Structure validation