PDB: 4050 件ウェブページステータス検索Chemie searchBIRD

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5LAC	SeMet Labeled Derivative of Cavally Virus 3CL Protease 分子名称: 3Cl Protease, GLYCEROL 著者 Kanitz, M, Heine, A, Diederich, W.E. 登録日 2016-06-14 公開日 2017-07-12 最終更新日 2019-05-22 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Structural basis for catalysis and substrate specificity of a 3C-like cysteine protease from a mosquito mesonivirus. Virology, 533, 2019
5LAK	Ligand-bound structure of Cavally Virus 3CL Protease 分子名称: 3Cl Protease, BEZ-TYR-TYR-ASN-ECC Peptide inhibitor, PENTAETHYLENE GLYCOL, ... 著者 Kanitz, M, Heine, A, Diederich, W.E. 登録日 2016-06-14 公開日 2017-07-12 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.299 Å) 主引用文献 Structural basis for catalysis and substrate specificity of a 3C-like cysteine protease from a mosquito mesonivirus. Virology, 533, 2019
7RC0	X-ray Structure of SARS-CoV-2 main protease covalently modified by compound GRL-091-20 分子名称: 3C-like proteinase, 5-chloro-4-methylpyridin-3-yl 1H-indole-4-carboxylate, SODIUM ION 著者 Mesecar, A.D, Anson, B.A, Ghosh, A.K, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2021-07-06 公開日 2021-09-29 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Indole Chloropyridinyl Ester-Derived SARS-CoV-2 3CLpro Inhibitors: Enzyme Inhibition, Antiviral Efficacy, Structure-Activity Relationship, and X-ray Structural Studies. J.Med.Chem., 64, 2021
7RC1	X-ray Structure of SARS-CoV main protease covalently modified by compound GRL-0686 分子名称: 3C-like proteinase, 5-chloropyridin-3-yl 1-(3-nitrobenzene-1-sulfonyl)-1H-indole-5-carboxylate, DIMETHYL SULFOXIDE 著者 Mesecar, A.D, Anson, B.A, Ghosh, A.K, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2021-07-07 公開日 2021-09-29 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 Indole Chloropyridinyl Ester-Derived SARS-CoV-2 3CLpro Inhibitors: Enzyme Inhibition, Antiviral Efficacy, Structure-Activity Relationship, and X-ray Structural Studies. J.Med.Chem., 64, 2021
5JD5	Crystal structure of MGS-MilE3, an alpha/beta hydrolase enzyme from the metagenome of pyrene-phenanthrene enrichment culture with sediment sample of Milazzo Harbor, Italy 分子名称: CHLORIDE ION, MGS-MilE3 著者 Stogios, P.J, Xu, X, Cui, H, Martinez-Martinez, M, Chernikova, T.N, Golyshin, P.N, Yakimov, M.M, Ferrer, M, Savchenko, A. 登録日 2016-04-15 公開日 2016-05-04 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal structure of MGS-MilE3, an alpha/beta hydrolase enzyme from the metagenome of pyrene-phenanthrene enrichment culture with sediment sample of Milazzo Harbor, Italy To Be Published
7RBZ	X-ray Structure of SARS-CoV-2 main protease covalently modified by compound GRL-017-20 分子名称: 3C-like proteinase, 5-chloropyridin-3-yl 2,3-dihydro-1H-indole-4-carboxylate 著者 Mesecar, A.D, Anson, B.A, Ghosh, A.K, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2021-07-06 公開日 2021-09-29 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Indole Chloropyridinyl Ester-Derived SARS-CoV-2 3CLpro Inhibitors: Enzyme Inhibition, Antiviral Efficacy, Structure-Activity Relationship, and X-ray Structural Studies. J.Med.Chem., 64, 2021
5H23	Crystal structure of Chikungunya virus capsid protein 分子名称: 1,2-ETHANEDIOL, Capsid Protein, DI(HYDROXYETHYL)ETHER, ... 著者 Sharma, R, Kesari, P, Tomar, S, Kumar, P. 登録日 2016-10-14 公開日 2018-03-14 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure-function insights into chikungunya virus capsid protein: Small molecules targeting capsid hydrophobic pocket. Virology, 515, 2018
5IEG	Murine endoplasmic reticulum alpha-glucosidase II with N-9'-methoxynonyl-1-deoxynojirimycin. 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, DIMETHYL SULFOXIDE, ... 著者 Caputo, A.T, Roversi, P, Alonzi, D.S, Kiappes, J.L, Zitzmann, N. 登録日 2016-02-25 公開日 2016-07-27 最終更新日 2024-04-24 実験手法 X-RAY DIFFRACTION (1.822 Å) 主引用文献 Structures of mammalian ER alpha-glucosidase II capture the binding modes of broad-spectrum iminosugar antivirals. Proc.Natl.Acad.Sci.USA, 113, 2016
8CB1	Crystal structure of human lysosomal acid-alpha-glucosidase, GAA, in complex with N-PNT-DNM 15 分子名称: (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[5-(phenanthren-9-ylmethoxy)pentyl]piperidine-3,4,5-triol, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Sulzenbacher, G, Roig-Zamboni, V, Overkleeft, H, Artola, M. 登録日 2023-01-25 公開日 2023-09-13 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Fluorescence polarisation activity-based protein profiling for the identification of deoxynojirimycin-type inhibitors selective for lysosomal retaining alpha- and beta-glucosidases. Chem Sci, 14, 2023
8CB6	Crystal structure of human lysosomal acid-alpha-glucosidase, GAA, in covalent complex with TAMRA tagged 1,6-Epi-cylcophellitol aziridine activity based probe 分子名称: (1S,2R,3R,4R,5R)-5-[8-[4-(4-azanylbutyl)-1,2,3-triazol-1-yl]octylamino]-4-(hydroxymethyl)cyclohexane-1,2,3-triol, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Sulzenbacher, G, Roig-Zamboni, V, Overkleeft, H, Artola, M. 登録日 2023-01-25 公開日 2023-09-13 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Fluorescence polarisation activity-based protein profiling for the identification of deoxynojirimycin-type inhibitors selective for lysosomal retaining alpha- and beta-glucosidases. Chem Sci, 14, 2023
1P3E	Structure of Glu endopeptidase in complex with MPD 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, glutamyl-endopeptidase 著者 Meijers, R, Blagova, E.V, Levdikov, V.M, Rudenskaya, G.N, Chestukhina, G.G, Akimkina, T.V, Kostrov, S.V, Lamzin, V.S, Kuranova, I.P. 登録日 2003-04-17 公開日 2004-04-27 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 The crystal structure of glutamyl endopeptidase from Bacillus intermedius reveals a structural link between zymogen activation and charge compensation. Biochemistry, 43, 2004
4R67	Human constitutive 20S proteasome in complex with carfilzomib 分子名称: N-{(2S)-2-[(morpholin-4-ylacetyl)amino]-4-phenylbutanoyl}-L-leucyl-N-[(2R,3S,4S)-1,3-dihydroxy-2,6-dimethylheptan-4-yl]-L-phenylalaninamide, Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, ... 著者 Sacchettini, J.C, Harshbarger, W.H. 登録日 2014-08-22 公開日 2015-02-11 最終更新日 2015-02-18 実験手法 X-RAY DIFFRACTION (2.89 Å) 主引用文献 Crystal Structure of the Human 20S Proteasome in Complex with Carfilzomib. Structure, 23, 2015
4R3O	Human Constitutive 20S Proteasome 分子名称: Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, ... 著者 Sacchettini, J.C, Harshbarger, W.H. 登録日 2014-08-16 公開日 2015-01-28 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal Structure of the Human 20S Proteasome in Complex with Carfilzomib. Structure, 23, 2015
6LF5	The solution structure of ShSPI 分子名称: ShSPI 著者 Luan, N, Rong, M.Q, Liu, J.X, Lai, R. 登録日 2019-11-29 公開日 2020-12-02 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Identification and Characterization of ShSPI, a Kazal-Type Elastase Inhibitor from the Venom of Scolopendra Hainanum . Toxins, 11, 2019
7DKD	Stenotrophomonas maltophilia DPP7 in complex with Asn-Tyr 分子名称: ASPARAGINE, Dipeptidyl-peptidase, GLYCEROL, ... 著者 Sakamoto, Y, Nakamura, A, Suzuki, Y, Honma, N, Roppongi, S, Kushibiki, C, Yonezawa, N, Takahashi, M, Shida, Y, Gouda, H, Nonaka, T, Ogasawara, W, Tanaka, N. 登録日 2020-11-23 公開日 2021-11-03 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Structural basis for an exceptionally strong preference for asparagine residue at the S2 subsite of Stenotrophomonas maltophilia dipeptidyl peptidase 7. Sci Rep, 11, 2021
7DKC	Stenotrophomonas maltophilia DPP7 in complex with Tyr-Tyr 分子名称: Dipeptidyl-peptidase, GLYCEROL, TYROSINE 著者 Sakamoto, Y, Nakamura, A, Suzuki, Y, Honma, N, Roppongi, S, Kushibiki, C, Yonezawa, N, Takahashi, M, Shida, Y, Gouda, H, Nonaka, T, Ogasawara, W, Tanaka, N. 登録日 2020-11-23 公開日 2021-11-03 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Structural basis for an exceptionally strong preference for asparagine residue at the S2 subsite of Stenotrophomonas maltophilia dipeptidyl peptidase 7. Sci Rep, 11, 2021
7DKE	Stenotrophomonas maltophilia DPP7 in complex with Phe-Tyr 分子名称: Dipeptidyl-peptidase, GLYCEROL, PHENYLALANINE, ... 著者 Sakamoto, Y, Nakamura, A, Suzuki, Y, Honma, N, Roppongi, S, Kushibiki, C, Yonezawa, N, Takahashi, M, Shida, Y, Gouda, H, Nonaka, T, Ogasawara, W, Tanaka, N. 登録日 2020-11-23 公開日 2021-11-03 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Structural basis for an exceptionally strong preference for asparagine residue at the S2 subsite of Stenotrophomonas maltophilia dipeptidyl peptidase 7. Sci Rep, 11, 2021
7DKB	Stenotrophomonas maltophilia DPP7 in complex with Val-Tyr 分子名称: Dipeptidyl-peptidase, TYROSINE, VALINE 著者 Sakamoto, Y, Nakamura, A, Suzuki, Y, Honma, N, Roppongi, S, Kushibiki, C, Yonezawa, N, Takahashi, M, Shida, Y, Gouda, H, Nonaka, T, Ogasawara, W, Tanaka, N. 登録日 2020-11-23 公開日 2021-11-03 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Structural basis for an exceptionally strong preference for asparagine residue at the S2 subsite of Stenotrophomonas maltophilia dipeptidyl peptidase 7. Sci Rep, 11, 2021
7O85	Anthrax toxin prepore in complex with the neutralizing Fab cAb29 分子名称: CALCIUM ION, Fab, Protective antigen PA-63 著者 Hoelzgen, F, Zalk, R, Alcalay, R, Cohen-Schwartz, S, Garau, G, Shahar, A, Mazor, O, Frank, G.A. 登録日 2021-04-14 公開日 2021-04-28 最終更新日 2021-09-29 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Neutralization of the anthrax toxin by antibody-mediated stapling of its membrane-penetrating loop. Acta Crystallogr D Struct Biol, 77, 2021
7N1N	Prx in complex with ComR DNA-binding domain 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ComR, Prx 著者 Rutbeek, N.R, Prehna, G. 登録日 2021-05-27 公開日 2021-07-28 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Molecular mechanism of quorum sensing inhibition in Streptococcus by the phage protein paratox. J.Biol.Chem., 297, 2021
3LKU	Crystal structure of S. cerevisiae Get4 in complex with an N-terminal fragment of Get5 分子名称: PROLINE, UPF0363 protein YOR164C, Ubiquitin-like protein MDY2 著者 Chartron, J.W, Clemons Jr, W.M. 登録日 2010-01-27 公開日 2010-06-23 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural characterization of the Get4/Get5 complex and its interaction with Get3. Proc.Natl.Acad.Sci.USA, 107, 2010
4MVT	Crystal structure of SUMO E3 Ligase PIAS3 分子名称: CHLORIDE ION, E3 SUMO-protein ligase PIAS3, UNKNOWN ATOM OR ION, ... 著者 Dong, A, Hu, J, Li, Y, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC) 登録日 2013-09-24 公開日 2013-10-16 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of SUMO E3 Ligase PIAS3 to be published
4NAM	1.7A structure of 5-Fluoro Tryptophan Labeled Protective Antigen (W206Y) 分子名称: CALCIUM ION, Protective antigen 著者 Lovell, S, Battaile, K.P, Chadegani, F, Mulangi, V, Miyagi, M, Bann, J.G. 登録日 2013-10-22 公開日 2014-01-22 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 (19)F nuclear magnetic resonance and crystallographic studies of 5-fluorotryptophan-labeled anthrax protective antigen and effects of the receptor on stability. Biochemistry, 53, 2014
8T3J	Crystal structure of native exfoliative toxin C (ExhC) from Mammaliicoccus sciuri 分子名称: Exfoliative toxin C 著者 Calil, F.A, Gismene, C, Hernandez Gonzalez, J.E, Ziem Nascimento, A.F, Santisteban, A.R.N, Arni, R.K, Barros Mariutti, R. 登録日 2023-06-07 公開日 2023-11-08 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.705 Å) 主引用文献 Necrotic activity of ExhC from Mammaliicoccus sciuri is mediated by specific amino acid residues. Int.J.Biol.Macromol., 254, 2024
8T3I	Crystal structure of mutant exfoliative toxin C (ExhC) from Mammaliicoccus sciuri 分子名称: Exfoliative toxin C 著者 Gismene, C, Calil, F.A, Hernandez Gonzalez, J.E, Ziem Nascimento, A.F, Santisteban, A.R.N, Arni, R.K, Barros Mariutti, R. 登録日 2023-06-07 公開日 2023-11-08 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 Necrotic activity of ExhC from Mammaliicoccus sciuri is mediated by specific amino acid residues. Int.J.Biol.Macromol., 254, 2024

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