7NJ7
| 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8200 core | 分子名称: | Nb8200 core, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ... | 著者 | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | 登録日 | 2021-02-16 | 公開日 | 2021-12-01 | 最終更新日 | 2022-02-09 | 実験手法 | ELECTRON MICROSCOPY (4.82 Å) | 主引用文献 | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
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7NKA
| 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8206 | 分子名称: | NB8206, Polymerase acidic protein, Polymerase basic protein 2,Polymerase basic protein 2, ... | 著者 | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | 登録日 | 2021-02-17 | 公開日 | 2021-12-01 | 最終更新日 | 2022-02-09 | 実験手法 | ELECTRON MICROSCOPY (4.07 Å) | 主引用文献 | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
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7NK4
| 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8203 core | 分子名称: | Nanobody 8203, Polymerase acidic protein, Polymerase basic protein 2,Polymerase basic protein 2, ... | 著者 | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | 登録日 | 2021-02-17 | 公開日 | 2021-12-01 | 最終更新日 | 2024-10-16 | 実験手法 | ELECTRON MICROSCOPY (5.32 Å) | 主引用文献 | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
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7NJ3
| 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8196 core | 分子名称: | Nanobody8196 core, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ... | 著者 | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | 登録日 | 2021-02-15 | 公開日 | 2021-12-01 | 最終更新日 | 2024-10-09 | 実験手法 | ELECTRON MICROSCOPY (4.48 Å) | 主引用文献 | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
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7NIR
| 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8191 core | 分子名称: | Nanobody8191 core, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ... | 著者 | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | 登録日 | 2021-02-13 | 公開日 | 2021-12-01 | 最終更新日 | 2022-02-09 | 実験手法 | ELECTRON MICROSCOPY (6.7 Å) | 主引用文献 | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
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7NK8
| 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8205 core | 分子名称: | Nb8205, Polymerase acidic protein, Polymerase basic protein 2,Polymerase basic protein 2, ... | 著者 | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | 登録日 | 2021-02-17 | 公開日 | 2021-12-01 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (5.34 Å) | 主引用文献 | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
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7NK2
| 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8202 core | 分子名称: | Nanobody8202, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ... | 著者 | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | 登録日 | 2021-02-17 | 公開日 | 2021-12-01 | 最終更新日 | 2022-02-09 | 実験手法 | ELECTRON MICROSCOPY (4.84 Å) | 主引用文献 | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
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4Q5S
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1Y14
| Crystal structure of yeast subcomplex of Rpb4 and Rpb7 | 分子名称: | DNA-directed RNA polymerase II 19 kDa polypeptide, DNA-directed RNA polymerase II 32 kDa polypeptide | 著者 | Armache, K.-J, Mitterweger, S, Meinhart, A, Cramer, P. | 登録日 | 2004-11-17 | 公開日 | 2004-12-14 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structures of Complete RNA Polymerase II and Its Subcomplex, Rpb4/7 J.Biol.Chem., 280, 2005
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7CUN
| The structure of human Integrator-PP2A complex | 分子名称: | Integrator complex subunit 1, Integrator complex subunit 11, Integrator complex subunit 2, ... | 著者 | Zheng, H, Qi, Y, Liu, W, Li, J, Wang, J, Xu, Y. | 登録日 | 2020-08-23 | 公開日 | 2020-11-25 | 最終更新日 | 2020-12-09 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Identification of Integrator-PP2A complex (INTAC), an RNA polymerase II phosphatase. Science, 370, 2020
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2L0I
| Solution structure of Rtt103 CTD-interacting domain bound to a Ser2 phosphorylated CTD peptide | 分子名称: | DNA-directed RNA polymerase, Regulator of Ty1 transposition protein 103 | 著者 | Lunde, B.M, Reichow, S.L, Kim, M, Suh, H, Leeper, T.C, Yang, F, Mutschler, H, Buratowski, S, Meinhart, A, Varani, G. | 登録日 | 2010-07-06 | 公開日 | 2010-09-08 | 最終更新日 | 2011-07-13 | 実験手法 | SOLUTION NMR | 主引用文献 | Cooperative interaction of transcription termination factors with the RNA polymerase II C-terminal domain. Nat.Struct.Mol.Biol., 17, 2010
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4FQG
| Crystal structure of the TCERG1 FF4-6 tandem repeat domain | 分子名称: | CHLORIDE ION, NICKEL (II) ION, Transcription elongation regulator 1 | 著者 | Liu, J, Fan, S, Lee, C.J, Greenleaf, A.L, Zhou, P. | 登録日 | 2012-06-25 | 公開日 | 2013-02-27 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Specific Interaction of the Transcription Elongation Regulator TCERG1 with RNA Polymerase II Requires Simultaneous Phosphorylation at Ser2, Ser5, and Ser7 within the Carboxyl-terminal Domain Repeat. J.Biol.Chem., 288, 2013
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7AOD
| Schizosaccharomyces pombe RNA polymerase I (dimer) | 分子名称: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit rpa1, DNA-directed RNA polymerase I subunit rpa14, ... | 著者 | Heiss, F, Daiss, J, Becker, P, Engel, C. | 登録日 | 2020-10-14 | 公開日 | 2021-02-24 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Conserved strategies of RNA polymerase I hibernation and activation. Nat Commun, 12, 2021
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7AOE
| Schizosaccharomyces pombe RNA polymerase I (elongation complex) | 分子名称: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit rpa1, DNA-directed RNA polymerase I subunit rpa14, ... | 著者 | Heiss, F, Daiss, J, Becker, P, Engel, C. | 登録日 | 2020-10-14 | 公開日 | 2021-02-24 | 最終更新日 | 2024-10-09 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Conserved strategies of RNA polymerase I hibernation and activation. Nat Commun, 12, 2021
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7AOC
| Schizosaccharomyces pombe RNA polymerase I (monomer) | 分子名称: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit rpa1, DNA-directed RNA polymerase I subunit rpa14, ... | 著者 | Heiss, F, Daiss, J, Becker, P, Engel, C. | 登録日 | 2020-10-14 | 公開日 | 2021-02-24 | 最終更新日 | 2024-10-16 | 実験手法 | ELECTRON MICROSCOPY (3.84 Å) | 主引用文献 | Conserved strategies of RNA polymerase I hibernation and activation. Nat Commun, 12, 2021
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8R65
| 1918 H1N1 Viral polymerase heterotrimer in complex with 4 repeat serine-5 phosphorylated PolII peptide with ordered PB2 C-terminal domains | 分子名称: | Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*CP*C)-3'), ... | 著者 | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | 登録日 | 2023-11-20 | 公開日 | 2024-03-27 | 最終更新日 | 2024-10-09 | 実験手法 | ELECTRON MICROSCOPY (4.23 Å) | 主引用文献 | Structural and functional characterization of the interaction between the influenza A virus RNA polymerase and the CTD of host RNA polymerase II. J.Virol., 98, 2024
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7NKY
| RNA Polymerase II-Spt4/5-nucleosome-FACT structure | 分子名称: | Chromatin elongation factor SPT4, DNA (138-MER), DNA (148-MER), ... | 著者 | Farnung, L, Ochmann, M, Engeholm, M, Cramer, P. | 登録日 | 2021-02-19 | 公開日 | 2021-07-07 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural basis of nucleosome transcription mediated by Chd1 and FACT. Nat.Struct.Mol.Biol., 28, 2021
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5N61
| RNA polymerase I initially transcribing complex | 分子名称: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | 著者 | Engel, C, Gubbey, T, Neyer, S, Sainsbury, S, Oberthuer, C, Baejen, C, Bernecky, C, Cramer, P. | 登録日 | 2017-02-14 | 公開日 | 2017-04-05 | 最終更新日 | 2024-10-16 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural Basis of RNA Polymerase I Transcription Initiation. Cell, 169, 2017
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7OB9
| Cryo-EM structure of human RNA Polymerase I in elongation state | 分子名称: | DNA non-template strand, DNA template strand, DNA-directed RNA polymerase I subunit RPA1, ... | 著者 | Misiaszek, A.D, Girbig, M, Mueller, C.W. | 登録日 | 2021-04-21 | 公開日 | 2021-12-08 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Cryo-EM structures of human RNA polymerase I. Nat.Struct.Mol.Biol., 28, 2021
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7OBB
| Cryo-EM structure of human RNA Polymerase I Open Complex | 分子名称: | DNA non-template strand, DNA template strand, DNA-directed RNA polymerase I subunit RPA1, ... | 著者 | Misiaszek, A.D, Girbig, M, Mueller, C.W. | 登録日 | 2021-04-21 | 公開日 | 2021-12-08 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Cryo-EM structures of human RNA polymerase I. Nat.Struct.Mol.Biol., 28, 2021
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7OBA
| Cryo-EM structure of human RNA Polymerase I in complex with RRN3 | 分子名称: | DNA-directed RNA polymerase I subunit RPA1, DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA2, ... | 著者 | Misiaszek, A.D, Girbig, M, Mueller, C.W. | 登録日 | 2021-04-21 | 公開日 | 2021-12-08 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Cryo-EM structures of human RNA polymerase I. Nat.Struct.Mol.Biol., 28, 2021
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5OA1
| RNA polymerase I pre-initiation complex | 分子名称: | ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA, ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA, ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA-ALA, ... | 著者 | Sadian, Y, Tafur, L, Kosinski, J, Jakobi, A.J, Muller, C.W. | 登録日 | 2017-06-20 | 公開日 | 2017-07-26 | 最終更新日 | 2018-10-24 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Structural insights into transcription initiation by yeast RNA polymerase I. EMBO J., 36, 2017
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7OQ4
| Cryo-EM structure of the ATV RNAP Inhibitory Protein (RIP) bound to the DNA-binding channel of the host's RNA polymerase | 分子名称: | Conserved protein, DNA-directed RNA polymerase subunit A', DNA-directed RNA polymerase subunit A'', ... | 著者 | Pilotto, S, Fouqueau, T, Lukoyanova, N, Sheppard, C, Lucas-Staat, S, Diaz-Santin, L.M, Matelska, D, Prangishvili, D, Cheung, A.C.M, Werner, F. | 登録日 | 2021-06-02 | 公開日 | 2021-08-25 | 最終更新日 | 2021-10-13 | 実験手法 | ELECTRON MICROSCOPY (3.27 Å) | 主引用文献 | Structural basis of RNA polymerase inhibition by viral and host factors. Nat Commun, 12, 2021
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6HKO
| Yeast RNA polymerase I elongation complex bound to nucleotide analog GMPCPP | 分子名称: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | 著者 | Tafur, L, Sadian, Y, Weis, F, Muller, C.W. | 登録日 | 2018-09-07 | 公開日 | 2019-04-03 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.42 Å) | 主引用文献 | The cryo-EM structure of a 12-subunit variant of RNA polymerase I reveals dissociation of the A49-A34.5 heterodimer and rearrangement of subunit A12.2. Elife, 8, 2019
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6HLS
| Yeast apo RNA polymerase I* | 分子名称: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | 著者 | Tafur, L, Sadian, Y, Weis, F, Muller, C.W. | 登録日 | 2018-09-11 | 公開日 | 2019-04-03 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.21 Å) | 主引用文献 | The cryo-EM structure of a 12-subunit variant of RNA polymerase I reveals dissociation of the A49-A34.5 heterodimer and rearrangement of subunit A12.2. Elife, 8, 2019
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