7NIS
1918 H1N1 Viral influenza polymerase heterotrimer with Nb8192 core
Summary for 7NIS
| Entry DOI | 10.2210/pdb7nis/pdb |
| EMDB information | 12364 |
| Descriptor | Nanobody8192 core, Polymerase acidic protein, RNA-directed RNA polymerase catalytic subunit, ... (6 entities in total) |
| Functional Keywords | influenza, rna polymerase, h1n1, 1918, viral protein, nanobody |
| Biological source | Camelidae mixed library More |
| Total number of polymer chains | 6 |
| Total formula weight | 296444.04 |
| Authors | Keown, J.R.,Carrique, L.,Fodor, E.,Grimes, J.M. (deposition date: 2021-02-13, release date: 2021-12-01, Last modification date: 2022-02-09) |
| Primary citation | Keown, J.R.,Zhu, Z.,Carrique, L.,Fan, H.,Walker, A.P.,Serna Martin, I.,Pardon, E.,Steyaert, J.,Fodor, E.,Grimes, J.M. Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13:251-251, 2022 Cited by PubMed: 35017564DOI: 10.1038/s41467-021-27950-w PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (5.96 Å) |
Structure validation
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