PDB: 1376 件ウェブページステータス検索Chemie searchBIRD

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1U13	Crystal structure analysis of the C37L/C151T/C442A-triple mutant of CYP51 from Mycobacterium tuberculosis 分子名称: Cytochrome P450 51, PROTOPORPHYRIN IX CONTAINING FE 著者 Podust, L.M, Yermalitskaya, L.V, Kim, Y, Waterman, M.R. 登録日 2004-07-14 公開日 2004-07-27 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Crystal structure analysis of the C37L/C151T/C442A-triple mutant of CYP51 from Mycobacterium tuberculosis To be published
1S1F	Crystal Structure of Streptomyces Coelicolor A3(2) CYP158A2 from antibiotic biosynthetic pathways 分子名称: 4-PHENYL-1H-IMIDAZOLE, GLYCEROL, MALONIC ACID, ... 著者 Zhao, B, Lamb, D.C, Lei, L, Sundaramoorthy, M, Podust, L.M, Waterman, M.R. 登録日 2004-01-06 公開日 2005-01-11 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Binding of Two Flaviolin Substrate Molecules, Oxidative Coupling, and Crystal Structure of Streptomyces coelicolor A3(2) Cytochrome P450 158A2 J.Biol.Chem., 280, 2005
4RSN	Crystal structure of the E267V mutant of cytochrome P450 BM3 分子名称: Bifunctional P-450/NADPH-P450 reductase, PROTOPORPHYRIN IX CONTAINING FE 著者 Zhou, W.H, Zhang, A.L, Zhang, T, Ren, X.K, Yorke, J.A, Taylor, A, Wong, L.-L. 登録日 2014-11-09 公開日 2015-12-02 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.701 Å) 主引用文献 Expanding the drug metabolism function of P450BM3 To be Published
4RUI	Crystal structure of a cytochrome P450 2A6 in complex with a monoterpene - sabinene. 分子名称: Cytochrome P450 2A6, PROTOPORPHYRIN IX CONTAINING FE, Sabinene 著者 Shah, M.B, Stout, C.D, Halpert, J.R. 登録日 2014-11-19 公開日 2015-01-28 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.61 Å) 主引用文献 Structural and Biophysical Characterization of Human Cytochromes P450 2B6 and 2A6 Bound to Volatile Hydrocarbons: Analysis and Comparison. Mol.Pharmacol., 87, 2015
4RM4	The crystal structure of the versatile cytochrome P450 enzyme CYP109B1 from Bacillus subtilis 分子名称: Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE 著者 Zhouw, W.H, Zhang, A.L, Zhang, T, Hall, E.A, Hutchinson, S, Cryle, M.J, Wong, L.-L, Bell, S.G. 登録日 2014-10-18 公開日 2015-02-04 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.771 Å) 主引用文献 The crystal structure of the versatile cytochrome P450 enzyme CYP109B1 from Bacillus subtilis. Mol Biosyst, 11, 2015
4TPN	High-resolution structure of TxtE in the absence of substrate 分子名称: GLYCEROL, LITHIUM ION, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Cahn, J.K.B, Dodani, S.C, Brinkmann-Chen, S, Heinsich, T, McIntosh, J.A, Arnold, F.H. 登録日 2014-06-08 公開日 2014-09-10 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.18 Å) 主引用文献 Structural, Functional, and Spectroscopic Characterization of the Substrate Scope of the Novel Nitrating Cytochrome P450 TxtE. Chembiochem, 15, 2014
4UAX	X-ray crystal structure of ligand free CYP142A2 from Mycobacterium smegmatis 分子名称: P450 heme-thiolate protein, PROTOPORPHYRIN IX CONTAINING FE 著者 Madrona, Y. 登録日 2014-08-11 公開日 2014-09-17 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Cholesterol ester oxidation by mycobacterial cytochrome p450. J.Biol.Chem., 289, 2014
1ROM	CRYSTAL STRUCTURE OF NITRIC REDUCTASE FROM DENITRIFYING FUNGUS FUSARIUM OXYSPORUM 分子名称: CYTOCHROME P450, PROTOPORPHYRIN IX CONTAINING FE 著者 Park, S.-Y, Nakagawa, A. 登録日 1997-03-24 公開日 1997-10-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of nitric oxide reductase from denitrifying fungus Fusarium oxysporum. Nat.Struct.Biol., 4, 1997
4TUV	X-ray crystal structure of CYP119 from Sulfolobus acidocaldarius, complexed with 4-(4-chlorophenyl)imidazole 分子名称: 4-(4-CHLOROPHENYL)IMIDAZOLE, Cytochrome P450 119, PROTOPORPHYRIN IX CONTAINING FE 著者 Madrona, Y. 登録日 2014-06-24 公開日 2015-02-18 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.501 Å) 主引用文献 NMR and X-ray Analysis of CYP119 Ligand Dependent Conformational Changes. To Be Published
4TRI	X-ray crystal structure of CYP142A2 from Mycobacterium smegmatis, complexed with cholesterol sulfate. 分子名称: CHOLEST-5-EN-3-YL HYDROGEN SULFATE, GLYCEROL, P450 heme-thiolate protein, ... 著者 Madrona, Y, Ortiz de Montellano, P. 登録日 2014-06-17 公開日 2014-09-17 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Cholesterol ester oxidation by mycobacterial cytochrome p450. J.Biol.Chem., 289, 2014
4TPO	High-resolution structure of TxtE with bound tryptophan substrate 分子名称: GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, Putative P450-like protein, ... 著者 Cahn, J.K.B, Dodani, S.C, Brinkmann-Chen, S, Heinsich, T, McIntosh, J.A, Arnold, F.H. 登録日 2014-06-08 公開日 2014-09-10 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.225 Å) 主引用文献 Structural, Functional, and Spectroscopic Characterization of the Substrate Scope of the Novel Nitrating Cytochrome P450 TxtE. Chembiochem, 15, 2014
4TT5	Crystal Structure of CYP119 from Sulfolobus acidocaldarius, complexed with 4-(4-bromophenyl)-1H imidazole 分子名称: 4-(4-bromophenyl)-1H-imidazole, Cytochrome P450 119, GLYCEROL, ... 著者 Madrona, Y. 登録日 2014-06-19 公開日 2015-02-18 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.18 Å) 主引用文献 NMR and X-ray Analysis of CYP119 ligand-dependent conformational changes To Be Published
4TVF	OxyB from Actinoplanes teichomyceticus 分子名称: OxyB, PROTOPORPHYRIN IX CONTAINING FE 著者 Haslinger, K, Cryle, M.J. 登録日 2014-06-26 公開日 2014-11-12 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Cytochrome P450 OxyBtei Catalyzes the First Phenolic Coupling Step in Teicoplanin Biosynthesis. Chembiochem, 15, 2014
1T86	Crystal Structure of the Ferrous Cytochrome P450cam Mutant (L358P/C334A) 分子名称: CAMPHOR, Cytochrome P450-cam, POTASSIUM ION, ... 著者 Nagano, S, Tosha, T, Ishimori, K, Morishima, I, Poulos, T.L. 登録日 2004-05-11 公開日 2004-05-25 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of the cytochrome p450cam mutant that exhibits the same spectral perturbations induced by putidaredoxin binding. J.Biol.Chem., 279, 2004
4RQL	Crystal structure of a human cytochrome P450 2B6 (Y226H/K262R) in complex with a monoterpene - sabinene 分子名称: 1,2-ETHANEDIOL, 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, Cytochrome P450 2B6, ... 著者 Shah, M.B. 登録日 2014-11-03 公開日 2015-01-28 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.105 Å) 主引用文献 Structural and Biophysical Characterization of Human Cytochromes P450 2B6 and 2A6 Bound to Volatile Hydrocarbons: Analysis and Comparison. Mol.Pharmacol., 87, 2015
4RRT	Crystal structure of a human cytochrome P450 2B6 (Y226H/K262R) in complex with (+)-3-carene 分子名称: (+)-3-carene, 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, Cytochrome P450 2B6, ... 著者 Shah, M.B. 登録日 2014-11-06 公開日 2015-01-28 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural and Biophysical Characterization of Human Cytochromes P450 2B6 and 2A6 Bound to Volatile Hydrocarbons: Analysis and Comparison. Mol.Pharmacol., 87, 2015
4UBS	The crystal structure of cytochrome P450 105D7 from Streptomyces avermitilis in complex with Diclofenac 分子名称: 2-[2,6-DICHLOROPHENYL)AMINO]BENZENEACETIC ACID, DI(HYDROXYETHYL)ETHER, PHOSPHATE ION, ... 著者 Xu, L.H, Ikeda, H, Arakawa, T, Wakagi, T, Shoun, H, Fushinobu, S. 登録日 2014-08-13 公開日 2014-11-05 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural basis for the 4'-hydroxylation of diclofenac by a microbial cytochrome P450 monooxygenase. Appl.Microbiol.Biotechnol., 99, 2015
1ULW	Crystal structure of P450nor Ser73Gly/Ser75Gly mutant 分子名称: Cytochrome P450 55A1, PROTOPORPHYRIN IX CONTAINING FE 著者 Oshima, R, Fushinobu, S, Su, F, Li, Z, Takaya, N, Shoun, H. 登録日 2003-09-16 公開日 2004-10-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural evidence for direct hydride transfer from NADH to cytochrome P450nor J.Mol.Biol., 342, 2004
4R21	Zebra fish cytochrome P450 17A2 with Progesterone 分子名称: Cytochrome P450 family 17 polypeptide 2, PROGESTERONE, PROTOPORPHYRIN IX CONTAINING FE 著者 Pallan, P.S, Egli, M. 登録日 2014-08-08 公開日 2014-12-31 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural and Kinetic Basis of Steroid 17 alpha, 20-Lyase Activity in Teleost Fish Cytochrome P450 17A1 and Its Absence in Cytochrome P450 17A2. J.Biol.Chem., 290, 2015
1TQN	Crystal Structure of Human Microsomal P450 3A4 分子名称: PROTOPORPHYRIN IX CONTAINING FE, cytochrome P450 3A4 著者 Yano, J.K, Wester, M.R, Schoch, G.A, Griffin, K.J, Stout, C.D, Johnson, E.F. 登録日 2004-06-17 公開日 2004-07-27 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 The Structure of Human Microsomal Cytochrome P450 3A4 Determined by X-ray Crystallography to 2.05-A Resolution J.Biol.Chem., 279, 2004
4UMZ	PikC D50N mutant in complex with the engineered substrate mimic bearing a 2-dimethylaminomethylbenzoate group 分子名称: (3R,4S,5S,7R,9E,11R,12R)-12-ethyl-3,5,7,11-tetramethyl-2,8-dioxooxacyclododec-9-en-4-yl 2-[(dimethylamino)methyl]benzoate, CYTOCHROME P450 HYDROXYLASE PIKC, PROTOPORPHYRIN IX CONTAINING FE 著者 Podust, L.M, Vieira, D.F. 登録日 2014-05-22 公開日 2015-06-17 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.32 Å) 主引用文献 Recognition of Synthetic Substrates by P450 Pikc To be Published
4UHI	HUMAN STEROL 14-ALPHA DEMETHYLASE (CYP51) IN COMPLEX WITH VFV IN C121 SPACE GROUP 分子名称: N-[(1R)-1-(3,4'-difluorobiphenyl-4-yl)-2-(1H-imidazol-1-yl)ethyl]-4-(5-phenyl-1,3,4-oxadiazol-2-yl)benzamide, PROTOPORPHYRIN IX CONTAINING FE, STEROL 14-ALPHA DEMETHYLASE 著者 Hargrove, T.Y, Wawrzak, Z, I Lepesheva, G. 登録日 2015-03-24 公開日 2016-06-08 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Human Sterol 14Alpha-Demethylase (Cyp51) as a Target for Anticancer Chemotherapy: Towards Structure-Aided Drug Design. J.Lipid Res., 57, 2016
4UHL	HUMAN STEROL 14-ALPHA DEMETHYLASE (CYP51) IN COMPLEX WITH VFV IN P1 SPACE GROUP 分子名称: N-[(1R)-1-(3,4'-difluorobiphenyl-4-yl)-2-(1H-imidazol-1-yl)ethyl]-4-(5-phenyl-1,3,4-oxadiazol-2-yl)benzamide, PROTOPORPHYRIN IX CONTAINING FE, STEROL 14-ALPHA DEMETHYLASE 著者 Hargrove, T.Y, Wawrzak, Z, I Lepesheva, G. 登録日 2015-03-24 公開日 2016-06-15 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Human Sterol 14Alpha-Demethylase (Cyp51) as a Target for Anticancer Chemotherapy: Towards Structure-Aided Drug Design. J.Lipid Res., 57, 2016
1SE6	Crystal Structure of Streptomyces Coelicolor A3(2) CYP158A2 from antibiotic biosynthetic pathways 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, PROTOPORPHYRIN IX CONTAINING FE, SPERMINE (FULLY PROTONATED FORM), ... 著者 Zhao, B, Lamb, D.C, Lei, L, Sundaramoorthy, M, Podust, L.M, Waterman, M.R. 登録日 2004-02-16 公開日 2005-01-25 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Binding of Two Flaviolin Substrate Molecules, Oxidative Coupling, and Crystal Structure of Streptomyces coelicolor A3(2) Cytochrome P450 158A2. J.Biol.Chem., 280, 2005
1SMI	A single mutation of P450 BM3 induces the conformational rearrangement seen upon substrate-binding in wild-type enzyme 分子名称: Bifunctional P-450:NADPH-P450 reductase, PROTOPORPHYRIN IX CONTAINING FE 著者 Joyce, M.G, Girvan, H.M, Munro, A.W, Leys, D. 登録日 2004-03-09 公開日 2004-06-08 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A Single Mutation in Cytochrome P450 BM3 Induces the Conformational Rearrangement Seen upon Substrate Binding in the Wild-type Enzyme J.Biol.Chem., 279, 2004

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