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4UBS

The crystal structure of cytochrome P450 105D7 from Streptomyces avermitilis in complex with Diclofenac

Summary for 4UBS
Entry DOI10.2210/pdb4ubs/pdb
DescriptorPentalenic acid synthase, PROTOPORPHYRIN IX CONTAINING FE, 2-[2,6-DICHLOROPHENYL)AMINO]BENZENEACETIC ACID, ... (7 entities in total)
Functional Keywordscytochrome p450, diclofenac, hydroxylation, oxidoreductase
Biological sourceStreptomyces avermitilis MA-4680 = NBRC 14893
Total number of polymer chains1
Total formula weight46814.57
Authors
Xu, L.H.,Ikeda, H.,Arakawa, T.,Wakagi, T.,Shoun, H.,Fushinobu, S. (deposition date: 2014-08-13, release date: 2014-11-05, Last modification date: 2024-03-20)
Primary citationXu, L.H.,Ikeda, H.,Liu, L.,Arakawa, T.,Wakagi, T.,Shoun, H.,Fushinobu, S.
Structural basis for the 4'-hydroxylation of diclofenac by a microbial cytochrome P450 monooxygenase.
Appl.Microbiol.Biotechnol., 99:3081-3091, 2015
Cited by
PubMed: 25341403
DOI: 10.1007/s00253-014-6148-y
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.2 Å)
Structure validation

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