1BON
 
 | | THREE-DIMENSIONAL STRUCTURE OF BOMBYXIN-II, AN INSULIN-RELATED BRAIN-SECRETORY PEPTIDE OF THE SILKMOTH BOMBYX MORI: COMPARISON WITH INSULIN AND RELAXIN | | 分子名称: | BOMBYXIN-II,BOMBYXIN A-2, BOMBYXIN-II,BOMBYXIN A-6 | | 著者 | Nagata, K, Hatanaka, H, Kohda, D, Inagaki, F, Structural Proteomics in Europe (SPINE) | | 登録日 | 1994-07-21 | | 公開日 | 1995-01-26 | | 最終更新日 | 2019-12-25 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Three-dimensional solution structure of bombyxin-II an insulin-like peptide of the silkmoth Bombyx mori: structural comparison with insulin and relaxin.
J.Mol.Biol., 253, 1995
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1B18
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1B9E
 | | HUMAN INSULIN MUTANT SERB9GLU | | 分子名称: | PROTEIN (INSULIN) | | 著者 | Wang, D.C, Zeng, Z.H, Yao, Z.P, Li, H.M. | | 登録日 | 1998-11-12 | | 公開日 | 1999-11-17 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure of an insulin dimer in an orthorhombic crystal: the structure analysis of a human insulin mutant (B9 Ser-->Glu).
Acta Crystallogr.,Sect.D, 55, 1999
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1DPH
 | | CONFORMATIONAL CHANGES IN CUBIC INSULIN CRYSTALS IN THE PH RANGE 7-11 | | 分子名称: | 1,2-DICHLOROETHANE, INSULIN A CHAIN (PH 11), INSULIN B CHAIN (PH 11), ... | | 著者 | Gursky, O, Badger, J, Li, Y, Caspar, D.L.D. | | 登録日 | 1992-10-30 | | 公開日 | 1993-01-15 | | 最終更新日 | 2017-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Conformational changes in cubic insulin crystals in the pH range 7-11.
Biophys.J., 63, 1992
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1B2D
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1B9G
 | | INSULIN-LIKE-GROWTH-FACTOR-1 | | 分子名称: | PROTEIN (GROWTH FACTOR IGF-1) | | 著者 | De Wolf, E, Gill, R, Geddes, S, Pitts, J, Wollmer, A, Grotzinger, J. | | 登録日 | 1999-02-11 | | 公開日 | 1999-02-23 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of a mini IGF-1.
Protein Sci., 5, 1996
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1BOM
 | | THREE-DIMENSIONAL STRUCTURE OF BOMBYXIN-II, AN INSULIN-RELATED BRAIN-SECRETORY PEPTIDE OF THE SILKMOTH BOMBYX MORI: COMPARISON WITH INSULIN AND RELAXIN | | 分子名称: | BOMBYXIN-II,BOMBYXIN A-2, BOMBYXIN-II,BOMBYXIN A-6 | | 著者 | Nagata, K, Hatanaka, H, Kohda, D, Inagaki, F. | | 登録日 | 1994-07-21 | | 公開日 | 1994-11-01 | | 最終更新日 | 2019-12-25 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Three-dimensional solution structure of bombyxin-II an insulin-like peptide of the silkmoth Bombyx mori: structural comparison with insulin and relaxin.
J.Mol.Biol., 253, 1995
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1BEN
 | | INSULIN COMPLEXED WITH 4-HYDROXYBENZAMIDE | | 分子名称: | 4-HYDROXYBENZAMIDE, CHLORIDE ION, HUMAN INSULIN, ... | | 著者 | Smith, G.D, Ciszak, E, Pangborn, W. | | 登録日 | 1996-02-15 | | 公開日 | 1996-07-11 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | A novel complex of a phenolic derivative with insulin: structural features related to the T-->R transition.
Protein Sci., 5, 1996
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1EV3
 | | Structure of the rhombohedral form of the M-cresol/insulin R6 hexamer | | 分子名称: | CHLORIDE ION, INSULIN, M-CRESOL, ... | | 著者 | Smith, G.D, Ciszak, E, Magrum, L.A, Pangborn, W.A, Blessing, R.H. | | 登録日 | 2000-04-19 | | 公開日 | 2000-12-04 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | R6 hexameric insulin complexed with m-cresol or resorcinol.
Acta Crystallogr.,Sect.D, 56, 2000
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1BQT
 | | THREE-DIMENSIONAL STRUCTURE OF HUMAN INSULIN-LIKE GROWTH FACTOR-I (IGF-I) DETERMINED BY 1H-NMR AND DISTANCE GEOMETRY, 6 STRUCTURES | | 分子名称: | INSULIN-LIKE GROWTH FACTOR-I | | 著者 | Sato, A, Nishimura, S, Ohkubo, T, Kyogoku, Y, Koyama, S, Kobayashi, M, Yasuda, T, Kobayashi, Y. | | 登録日 | 1998-08-18 | | 公開日 | 1999-05-18 | | 最終更新日 | 2022-02-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Three-dimensional structure of human insulin-like growth factor-I (IGF-I) determined by 1H-NMR and distance geometry.
Int.J.Pept.Protein Res., 41, 1993
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1EV6
 | | Structure of the monoclinic form of the M-cresol/insulin R6 hexamer | | 分子名称: | CHLORIDE ION, INSULIN, M-CRESOL, ... | | 著者 | Smith, G.D, Ciszak, E, Magrum, L.A, Pangborn, W.A, Blessing, R.H. | | 登録日 | 2000-04-19 | | 公開日 | 2000-12-04 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | R6 Hexameric Insulin Complexed with m-Cresol or Resorcinol
Biochem.Biophys.Res.Commun., 56, 2000
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1EVR
 | | The structure of the resorcinol/insulin R6 hexamer | | 分子名称: | CHLORIDE ION, INSULIN, RESORCINOL, ... | | 著者 | Smith, G.D, Ciszak, E, Magrum, L.A, Pangborn, W.A, Blessing, R.H. | | 登録日 | 2000-04-20 | | 公開日 | 2000-12-04 | | 最終更新日 | 2017-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | R6 hexameric insulin complexed with m-cresol or resorcinol.
Acta Crystallogr.,Sect.D, 56, 2000
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1EFE
 | | AN ACTIVE MINI-PROINSULIN, M2PI | | 分子名称: | MINI-PROINSULIN | | 著者 | Cho, Y, Chang, S.G, Choi, K.D, Shin, H, Ahn, B, Kim, K.S. | | 登録日 | 2000-02-08 | | 公開日 | 2000-03-17 | | 最終更新日 | 2022-02-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution Structure of an Active Mini-Proinsulin, M2PI: Inter-chain Flexibility is Crucial for Insulin Activity
J.Biochem.Mol.Biol., 33, 2000
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1CPH
 | | CONFORMATIONAL CHANGES IN CUBIC INSULIN CRYSTALS IN THE PH RANGE 7-11 | | 分子名称: | 1,2-DICHLOROETHANE, INSULIN (PH 10), SODIUM ION | | 著者 | Gursky, O, Badger, J, Li, Y, Caspar, D.L.D. | | 登録日 | 1992-10-30 | | 公開日 | 1993-01-15 | | 最終更新日 | 2017-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Conformational changes in cubic insulin crystals in the pH range 7-11.
Biophys.J., 63, 1992
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8CLS
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7WRQ
 | | Structure of Human IGF1/IGFBP3/ALS Ternary Complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin-like growth factor-binding protein 3, Insulin-like growth factor-binding protein complex acid labile subunit, ... | | 著者 | Kim, H, Fu, Y, Kim, H.M. | | 登録日 | 2022-01-27 | | 公開日 | 2022-08-10 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structural basis for assembly and disassembly of the IGF/IGFBP/ALS ternary complex
Nat Commun, 13, 2022
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2G54
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7KD6
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4OGA
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4XSS
 | | Insulin-like growth factor I in complex with site 1 of a hybrid insulin receptor / Type 1 insulin-like growth factor receptor | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin receptor, ... | | 著者 | Lawrence, C, Kong, G.K.-W, Menting, J.G, Lawrence, M.C. | | 登録日 | 2015-01-22 | | 公開日 | 2015-06-10 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural Congruency of Ligand Binding to the Insulin and Insulin/Type 1 Insulin-like Growth Factor Hybrid Receptors.
Structure, 23, 2015
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6VEP
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6FEY
 | | Crystal structure of Drosophila neural ectodermal development factor Imp-L2 with Drosophila DILP5 insulin | | 分子名称: | Neural/ectodermal development factor IMP-L2, Probable insulin-like peptide 5 | | 著者 | Brzozowski, A.M, Kulahin, N, Kristensen, O, Schluckebier, G, Meyts, P.D. | | 登録日 | 2018-01-03 | | 公開日 | 2018-09-26 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.48 Å) | | 主引用文献 | Structures of insect Imp-L2 suggest an alternative strategy for regulating the bioavailability of insulin-like hormones.
Nat Commun, 9, 2018
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6FF3
 | | Crystal structure of Drosophila neural ectodermal development factor Imp-L1 with Human IGF-I | | 分子名称: | Insulin-like growth factor I, Neural/ectodermal development factor IMP-L2 | | 著者 | Brzozowski, A.M, Kulahin, N, Kristensen, O, Schluckebier, G, Meyts, P.D, Viola, C.M. | | 登録日 | 2018-01-03 | | 公開日 | 2018-09-26 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | | 主引用文献 | Structures of insect Imp-L2 suggest an alternative strategy for regulating the bioavailability of insulin-like hormones.
Nat Commun, 9, 2018
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5KQV
 | | Insulin receptor ectodomain construct comprising domains L1,CR,L2, FnIII-1 and alphaCT peptide in complex with bovine insulin and FAB 83-14 (REVISED STRUCTURE) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin, Insulin receptor,Insulin receptor, ... | | 著者 | Lawrence, M.C, Smith, B.J, Croll, T.I. | | 登録日 | 2016-07-06 | | 公開日 | 2017-07-19 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (4.4 Å) | | 主引用文献 | How insulin engages its primary binding site on the insulin receptor.
Nature, 493, 2013
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3E4Z
 | | Crystal structure of human insulin degrading enzyme in complex with insulin-like growth factor II | | 分子名称: | Insulin-degrading enzyme, Insulin-like growth factor II, ZINC ION | | 著者 | Guo, Q, Manolopoulou, M, Tang, W.-J. | | 登録日 | 2008-08-12 | | 公開日 | 2009-08-18 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Molecular Basis for the Recognition and Cleavages of IGF-II, TGF-alpha, and Amylin by Human Insulin-Degrading Enzyme.
J.Mol.Biol., 395, 2010
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