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6QD2
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BU of 6qd2 by Molmil
MloK1 model from single particle analysis of 2D crystals, class 6 (intermediate compact conformation)
分子名称: Cyclic nucleotide-gated potassium channel mll3241, POTASSIUM ION
著者Righetto, R, Biyani, N, Kowal, J, Chami, M, Stahlberg, H.
登録日2018-12-31
公開日2019-04-24
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献Retrieving high-resolution information from disordered 2D crystals by single-particle cryo-EM.
Nat Commun, 10, 2019
8EP0
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BU of 8ep0 by Molmil
Eag Kv channel with voltage sensor in the intermediate conformation
分子名称: Calmodulin-1, Potassium voltage-gated channel subfamily H member 1
著者Mandala, V.S, MacKinnon, R.
登録日2022-10-04
公開日2022-11-16
実験手法ELECTRON MICROSCOPY (4.9 Å)
主引用文献Voltage-sensor movements in the Eag Kv channel under an applied electric field.
Proc.Natl.Acad.Sci.USA, 119, 2022
6QD3
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BU of 6qd3 by Molmil
MloK1 model from single particle analysis of 2D crystals, class 7 (intermediate conformation)
分子名称: Cyclic nucleotide-gated potassium channel mll3241, POTASSIUM ION
著者Righetto, R, Biyani, N, Kowal, J, Chami, M, Stahlberg, H.
登録日2018-12-31
公開日2019-04-24
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (5 Å)
主引用文献Retrieving high-resolution information from disordered 2D crystals by single-particle cryo-EM.
Nat Commun, 10, 2019
5CIZ
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BU of 5ciz by Molmil
E. coli RNA polymerase alpha subunit CTD in complex with CAP and DNA: A(5)-tract binding site for alpha CTD
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, DNA (5'-D(*CP*TP*AP*GP*AP*TP*CP*AP*CP*AP*TP*TP*TP*TP*AP*GP*GP*CP*AP*AP*AP*AP*AP*G)-3'), DNA (5'-D(*CP*TP*TP*TP*TP*TP*GP*CP*CP*TP*AP*AP*AP*AP*TP*GP*TP*GP*AP*T)-3'), ...
著者Napoli, A.A, Lawson, C.L.
登録日2015-07-13
公開日2016-06-29
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (5.0098 Å)
主引用文献The RNA Polymerase alpha Subunit Recognizes the DNA Shape of the Upstream Promoter Element
Biochemistry, 2020
6IAX
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BU of 6iax by Molmil
MloK1 model from single particle analysis of 2D crystals, class 1 (extended conformation)
分子名称: Cyclic nucleotide-gated potassium channel mll3241, POTASSIUM ION
著者Righetto, R, Biyani, N, Kowal, J, Chami, M, Stahlberg, H.
登録日2018-11-27
公開日2019-04-24
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (5.2 Å)
主引用文献Retrieving high-resolution information from disordered 2D crystals by single-particle cryo-EM.
Nat Commun, 10, 2019
6QD1
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BU of 6qd1 by Molmil
MloK1 model from single particle analysis of 2D crystals, class 5 (intermediate compact conformation)
分子名称: Cyclic nucleotide-gated potassium channel mll3241, POTASSIUM ION
著者Righetto, R, Biyani, N, Kowal, J, Chami, M, Stahlberg, H.
登録日2018-12-31
公開日2019-04-24
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (5.4 Å)
主引用文献Retrieving high-resolution information from disordered 2D crystals by single-particle cryo-EM.
Nat Commun, 10, 2019
8EP1
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BU of 8ep1 by Molmil
Eag Kv channel with voltage sensor in the down conformation
分子名称: Calmodulin-1, Potassium voltage-gated channel subfamily H member 1
著者Mandala, V.S, MacKinnon, R.
登録日2022-10-04
公開日2022-11-16
実験手法ELECTRON MICROSCOPY (5.4 Å)
主引用文献Voltage-sensor movements in the Eag Kv channel under an applied electric field.
Proc.Natl.Acad.Sci.USA, 119, 2022
6QD4
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BU of 6qd4 by Molmil
MloK1 model from single particle analysis of 2D crystals, class 8 (intermediate conformation)
分子名称: Cyclic nucleotide-gated potassium channel mll3241, POTASSIUM ION
著者Righetto, R, Biyani, N, Kowal, J, Chami, M, Stahlberg, H.
登録日2018-12-31
公開日2019-04-24
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (5.6 Å)
主引用文献Retrieving high-resolution information from disordered 2D crystals by single-particle cryo-EM.
Nat Commun, 10, 2019
6WJG
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BU of 6wjg by Molmil
PKA RIIbeta holoenzyme with DnaJB1-PKAc fusion in fibrolamellar hepatoceullar carcinoma
分子名称: DnaJ homolog subfamily B member 1, cAMP-dependent protein kinase catalytic subunit alpha fusion, cAMP-dependent protein kinase type II-beta regulatory subunit
著者Lu, T.-W, Aoto, P.C, Weng, J.-H, Nielsen, C, Cash, J.N, Hall, J, Zhang, P, Simon, S.M, Cianfrocco, M.A, Taylor, S.S.
登録日2020-04-13
公開日2020-12-02
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (6.2 Å)
主引用文献Structural analyses of the PKA RII beta holoenzyme containing the oncogenic DnaJB1-PKAc fusion protein reveal protomer asymmetry and fusion-induced allosteric perturbations in fibrolamellar hepatocellular carcinoma.
Plos Biol., 18, 2020
6VY0
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BU of 6vy0 by Molmil
SthK P300A cyclic nucleotide-gated potassium channel in a putative active state, in complex with cAMP
分子名称: SthK
著者Schmidpeter, P.A.M, Rheinberger, J, Nimigean, C.M.
登録日2020-02-25
公開日2020-11-11
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (6.68 Å)
主引用文献Prolyl isomerization controls activation kinetics of a cyclic nucleotide-gated ion channel.
Nat Commun, 11, 2020
4CHW
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BU of 4chw by Molmil
The electron crystallography structure of the cAMP-free potassium channel MloK1
分子名称: CYCLIC NUCLEOTIDE-GATED POTASSIUM CHANNEL MLL3241, POTASSIUM ION
著者Kowal, J, Chami, M, Baumgartner, P, Arheit, M, Chiu, P.L, Rangl, M, Scheuring, S, Schroeder, G.F, Nimigean, C.M, Stahlberg, H.
登録日2013-12-04
公開日2014-01-15
最終更新日2024-05-08
実験手法ELECTRON CRYSTALLOGRAPHY (7 Å)
主引用文献Ligand-induced structural changes in the cyclic nucleotide-modulated potassium channel MloK1.
Nat Commun, 5, 2014
4CHV
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BU of 4chv by Molmil
The electron crystallography structure of the cAMP-bound potassium channel MloK1
分子名称: CYCLIC NUCLEOTIDE-GATED POTASSIUM CHANNEL MLL3241, POTASSIUM ION
著者Kowal, J, Chami, M, Baumgartner, P, Arheit, M, Chiu, P.L, Rangl, M, Scheuring, S, Schroeder, G.F, Nimigean, C.M, Stahlberg, H.
登録日2013-12-04
公開日2014-01-15
最終更新日2024-05-08
実験手法ELECTRON CRYSTALLOGRAPHY (7 Å)
主引用文献Ligand-Induced Structural Changes in the Cyclic Nucleotide-Modulated Potassium Channel Mlok1
Nat.Commun., 5, 2014
6WJF
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BU of 6wjf by Molmil
PKA RIIbeta holoenzyme with DnaJB1-PKAc fusion in fibrolamellar hepatoceullar carcinoma
分子名称: DnaJ homolog subfamily B member 1,cAMP-dependent protein kinase catalytic subunit alpha fusion, cAMP-dependent protein kinase type II-beta regulatory subunit
著者Lu, T.-W, Aoto, P.C, Weng, J.-H, Nielsen, C, Cash, J.N, Hall, J, Zhang, P, Simon, S.M, Cianfrocco, M.A, Taylor, S.S.
登録日2020-04-13
公開日2020-12-02
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (7.5 Å)
主引用文献Structural analyses of the PKA RII beta holoenzyme containing the oncogenic DnaJB1-PKAc fusion protein reveal protomer asymmetry and fusion-induced allosteric perturbations in fibrolamellar hepatocellular carcinoma.
Plos Biol., 18, 2020
3IYD
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BU of 3iyd by Molmil
Three-dimensional EM structure of an intact activator-dependent transcription initiation complex
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Catabolite gene activator, DNA (98-MER), ...
著者Hudson, B.P, Quispe, J, Lara, S, Kim, Y, Berman, H, Arnold, E, Ebright, R.H, Lawson, C.L.
登録日2009-08-01
公開日2009-11-10
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (19.799999 Å)
主引用文献Three-dimensional EM structure of an intact activator-dependent transcription initiation complex
Proc.Natl.Acad.Sci.USA, 106, 2009
3J4Q
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BU of 3j4q by Molmil
Pseudo-atomic model of the AKAP18-PKA complex in a bent conformation derived from electron microscopy
分子名称: A-kinase anchor protein 18, cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase type II-alpha regulatory subunit
著者Reichow, S.L, Gonen, T.
登録日2013-09-25
公開日2013-11-13
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (35 Å)
主引用文献Intrinsic disorder within an AKAP-protein kinase A complex guides local substrate phosphorylation.
Elife, 2, 2013
3J4R
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BU of 3j4r by Molmil
Pseudo-atomic model of the AKAP18-PKA Complex in a linear conformation derived from electron microscopy
分子名称: A-kinase anchor protein 18, cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase type II-alpha regulatory subunit
著者Reichow, S.L, Gonen, T.
登録日2013-09-25
公開日2013-11-13
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (35 Å)
主引用文献Intrinsic disorder within an AKAP-protein kinase A complex guides local substrate phosphorylation.
Elife, 2, 2013
2D93
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BU of 2d93 by Molmil
Solution structure of the cNMP_binding domain of human Rap guanine nucleotide exchange factor 6
分子名称: Rap guanine nucleotide exchange factor 6
著者Inoue, K, Muto, Y, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-12-08
公開日2006-06-08
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the cNMP_binding domain of human Rap guanine nucleotide exchange factor 6
to be published
2MHF
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BU of 2mhf by Molmil
Solution structure of the cyclic-nucleotide binding homology domain of a KCNH channel
分子名称: Uncharacterized protein
著者Li, Q, Ng, H.
登録日2013-11-21
公開日2014-04-02
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution structure of the cyclic-nucleotide binding homology domain of a KCNH channel.
J.Struct.Biol., 186, 2014
2WC2
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BU of 2wc2 by Molmil
Nmr structure of catabolite activator protein in the unliganded state
分子名称: CATABOLITE GENE ACTIVATOR
著者Popovych, N, Tzeng, S.R, Kalodimos, C.G.
登録日2009-03-06
公開日2009-04-21
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural Basis for Camp-Mediated Allosteric Control of the Catabolite Activator Protein.
Proc.Natl.Acad.Sci.USA, 106, 2009
2K0G
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BU of 2k0g by Molmil
Solution Structure of a Bacterial Cyclic Nucleotide-Activated K+ Channel Binding Domain in Complex with cAMP
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Mll3241 protein
著者Schunke, S, Stoldt, M, Willbold, D.
登録日2008-02-02
公開日2009-02-10
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the Mesorhizobium loti K1 channel cyclic nucleotide-binding domain in complex with cAMP.
Embo Rep., 10, 2009
4BH9
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BU of 4bh9 by Molmil
A structural model of CAP mutant (T127L and S128I) in the apo state
分子名称: cAMP-activated global transcriptional regulator CRP
著者Tzeng, S.R, Kalodimos, C.G.
登録日2013-03-30
公開日2013-05-08
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Allosteric inhibition through suppression of transient conformational states.
Nat. Chem. Biol., 9, 2013
4BHP
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BU of 4bhp by Molmil
A structural model of CAP mutant (T127L and S128I) in cGMP-bound state
分子名称: CAMP RECEPTOR PROTEIN
著者Tzeng, S.R, Kalodimos, C.G.
登録日2013-04-04
公開日2013-05-08
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Allosteric Inhibition Through Suppression of Transient Conformational States.
Nat.Chem.Biol., 9, 2013
2N7G
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BU of 2n7g by Molmil
Structure of the cyclic nucleotide-binding homology domain of the hERG channel
分子名称: Potassium voltage-gated channel subfamily H member 2
著者Li, Y, Ng, H, Li, Q, Kang, C.
登録日2015-09-10
公開日2016-05-18
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure of the Cyclic Nucleotide-Binding Homology Domain of the hERG Channel and Its Insight into Type 2 Long QT Syndrome
Sci Rep, 6, 2016
2KXL
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BU of 2kxl by Molmil
Solution structure of a bacterial cyclic nucleotide-activated K+ channel binding domain in the unliganded state
分子名称: Cyclic nucleotide-gated potassium channel mll3241
著者Schunke, S, Stoldt, M, Willbold, D.
登録日2010-05-10
公開日2011-04-20
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural insights into conformational changes of a cyclic nucleotide-binding domain in solution from Mesorhizobium loti K1 channel.
Proc.Natl.Acad.Sci.USA, 108, 2011
2MPF
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BU of 2mpf by Molmil
Solution structure human HCN2 CNBD in the cAMP-unbound state
分子名称: Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
著者Saponaro, A, Pauleta, S.R, Cantini, F, Matzapetakis, M, Hammann, C, Banci, L, Thiel, G, Santoro, B, Moroni, A.
登録日2014-05-16
公開日2014-09-03
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural basis for the mutual antagonism of cAMP and TRIP8b in regulating HCN channel function.
Proc.Natl.Acad.Sci.USA, 111, 2014

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