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6SKZ
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BU of 6skz by Molmil
Structure of the closed conformation of CtTel1
分子名称: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase Tel1
著者Jansma, M, Eustermann, S.E, Kostrewa, D, Lammens, K, Hopfner, K.P.
登録日2019-08-16
公開日2019-10-30
最終更新日2020-01-15
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Near-Complete Structure and Model of Tel1ATM from Chaetomium thermophilum Reveals a Robust Autoinhibited ATP State.
Structure, 28, 2020
6T9K
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BU of 6t9k by Molmil
SAGA Core module
分子名称: Protein SPT3, SAGA-associated factor 73, Transcription factor SPT20, ...
著者Wang, H, Cheung, A, Cramer, P.
登録日2019-10-28
公開日2020-01-29
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structure of the transcription coactivator SAGA.
Nature, 577, 2020
6T59
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BU of 6t59 by Molmil
Structure of rabbit 80S ribosome translating beta-tubulin in complex with tetratricopeptide protein 5 and nascent chain-associated complex
分子名称: 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
著者Lin, Z, Gasic, I, Chandrasekaran, V, Peters, N, Shao, S, Ramakrishnan, V, Mitchison, T.J, Hegde, R.S.
登録日2019-10-15
公開日2019-11-27
最終更新日2020-01-15
実験手法ELECTRON MICROSCOPY (3.11 Å)
主引用文献TTC5 mediates autoregulation of tubulin via mRNA degradation.
Science, 367, 2020
2LEF
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BU of 2lef by Molmil
LEF1 HMG DOMAIN (FROM MOUSE), COMPLEXED WITH DNA (15BP), NMR, 12 STRUCTURES
分子名称: DNA (5'-D(*CP*AP*CP*CP*CP*TP*TP*TP*GP*AP*AP*GP*CP*TP*C)-3'), DNA (5'-D(*GP*AP*GP*CP*TP*TP*CP*AP*AP*AP*GP*GP*GP*TP*G)-3'), PROTEIN (LYMPHOID ENHANCER-BINDING FACTOR)
著者Li, X, Love, J.J, Case, D.A, Wright, P.E.
登録日1998-10-13
公開日1998-10-21
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Structural basis for DNA bending by the architectural transcription factor LEF-1.
Nature, 376, 1995
2LJ9
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BU of 2lj9 by Molmil
Partial 3d structure of the c-terminal part of the free arabidopsis thaliana cp12-2 in its oxidized form
分子名称: CP12 domain-containing protein 2
著者Trivelli, X, Sparla, F, Marri, L, Trost, P.
登録日2011-09-09
公開日2012-04-25
最終更新日2012-06-27
実験手法SOLUTION NMR
主引用文献Conformational Selection and Folding-upon-binding of Intrinsically Disordered Protein CP12 Regulate Photosynthetic Enzymes Assembly.
J.Biol.Chem., 287, 2012
2L9Q
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BU of 2l9q by Molmil
Structural Characterization of small heat shock protein (Hsp12)
分子名称: 12 kDa heat shock protein
著者Singarapu, K.K, Tonelli, M, Westler, W.M, Markley, J.L, Center for Eukaryotic Structural Genomics (CESG)
登録日2011-02-22
公開日2011-06-15
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural Characterization of small heat shock protein (Hsp12)
To be Published
2LJL
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BU of 2ljl by Molmil
NMR structure of Hsp12 in the presence of DPC
分子名称: 12 kDa heat shock protein
著者Singarapu, K, Markley, J, Center for Eukaryotic Structural Genomics (CESG)
登録日2011-09-20
公開日2011-10-12
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural characterization of Hsp12, the heat shock protein from Saccharomyces cerevisiae, in aqueous solution where it is intrinsically disordered and in detergent micelles where it is locally alpha-helical.
J.Biol.Chem., 286, 2011
2LY4
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BU of 2ly4 by Molmil
HMGB1-facilitated p53 DNA binding occurs via HMG-box/p53 transactivation domain interaction and is regulated by the acidic tail
分子名称: Cellular tumor antigen p53, High mobility group protein B1
著者Rowell, J.P, Simpson, K.L, Stott, K, Watson, M, Thomas, J.O.
登録日2012-09-12
公開日2012-10-31
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献HMGB1-Facilitated p53 DNA Binding Occurs via HMG-Box/p53 Transactivation Domain Interaction, Regulated by the Acidic Tail.
Structure, 20, 2012
2MU8
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BU of 2mu8 by Molmil
Residues belonging the n-terminal region derived of merozoite surface protein-2 of plasmodium falciparum
分子名称: MSP-2 peptide
著者Cifuentes, G, Patarroyo, M.E, Urquiza, M, Ramirez, L.E, Reyes, C, Rodriguez, R.
登録日2014-09-04
公開日2014-11-12
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Distorting malaria peptide backbone structure to enable fitting into MHC class II molecules renders modified peptides immunogenic and protective.
J.Med.Chem., 46, 2003
2O8A
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BU of 2o8a by Molmil
rat PP1cgamma complexed with mouse inhibitor-2
分子名称: Protein phosphatase inhibitor 2, Serine/threonine-protein phosphatase PP1-gamma catalytic subunit
著者Hurley, T.D.
登録日2006-12-12
公開日2007-07-17
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Structural basis for regulation of protein phosphatase 1 by inhibitor-2.
J.Biol.Chem., 282, 2007
2O8G
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BU of 2o8g by Molmil
Rat pp1c gamma complexed with mouse inhibitor-2
分子名称: MANGANESE (II) ION, Protein phosphatase inhibitor 2, Serine/threonine-protein phosphatase PP1-gamma catalytic subunit
著者Hurley, T.D.
登録日2006-12-12
公開日2007-07-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for regulation of protein phosphatase 1 by inhibitor-2.
J.Biol.Chem., 282, 2007
2PLB
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BU of 2plb by Molmil
D(GTATACC) under hydrostatic pressure of 1.39 GPa
分子名称: 5'-D(*DGP*DGP*DTP*DAP*DTP*DAP*DCP*DC)-3', SPERMINE
著者Prange, T, Girard, E, Kahn, R, Fourme, R.
登録日2007-04-19
公開日2007-07-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Adaptation of the base-paired double-helix molecular architecture to extreme pressure.
Nucleic Acids Res., 35, 2007
2PKV
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BU of 2pkv by Molmil
D-(GGTATACC) ambient pressure
分子名称: 5'-D(*GP*GP*TP*AP*TP*AP*CP*C)-3'
著者Girard, E, Prange, T, Kahn, R, Fourme, R.
登録日2007-04-18
公開日2007-07-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Adaptation of the base-paired double-helix molecular architecture to extreme pressure.
Nucleic Acids Res., 35, 2007
2PL4
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BU of 2pl4 by Molmil
D-(GGTATACC) under 0.55 GPa hydrostatic pressure
分子名称: Synthetic DNA octamer
著者Prange, T, Girard, E, Kahn, R, Fourme, R.
登録日2007-04-19
公開日2007-07-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Adaptation of the base-paired double-helix molecular architecture to extreme pressure.
Nucleic Acids Res., 35, 2007
2MWY
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BU of 2mwy by Molmil
Mdmx-p53
分子名称: Cellular tumor antigen p53, Protein Mdm4
著者Grace, C.R.
登録日2014-12-03
公開日2016-01-27
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Monitoring Ligand-Induced Protein Ordering in Drug Discovery.
J.Mol.Biol., 428, 2016
2PL8
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BU of 2pl8 by Molmil
D(GTATACC) under hydrostatic pressure of 1.04 GPa
分子名称: 5'-D(*DGP*DGP*DTP*DAP*DTP*DAP*DCP*DC)-3', SPERMINE
著者Prange, T, Girard, E, Fourme, R, Kahn, R.
登録日2007-04-19
公開日2007-07-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Adaptation of the base-paired double-helix molecular architecture to extreme pressure.
Nucleic Acids Res., 35, 2007
3L82
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BU of 3l82 by Molmil
X-ray Crystal structure of TRF1 and Fbx4 complex
分子名称: F-box only protein 4, Telomeric repeat-binding factor 1
著者Zeng, Z.X, Wang, W, Yang, Y.T, Chen, Y, Yang, X.M, Diehl, J.A, Liu, X.D, Lei, M.
登録日2009-12-29
公開日2010-03-09
最終更新日2013-09-25
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural Basis of Selective Ubiquitination of TRF1 by SCF(Fbx4)
Dev.Cell, 18, 2010
3MQS
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BU of 3mqs by Molmil
Crystal Structure of the USP7:Hdm2(PSTS) complex
分子名称: Hdm2 peptide, Ubiquitin carboxyl-terminal hydrolase 7
著者Saridakis, V.
登録日2010-04-28
公開日2010-08-25
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structure of USP7
To be Published
3ORD
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BU of 3ord by Molmil
Structural Evidence for Stabilization of Inhibitor Binding by a Protein Cavity in the Dehaloperoxidase-Hemoglobin from Amphitrite ornata
分子名称: Dehaloperoxidase A, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, ...
著者de Serrano, V.S, Franzen, S.
登録日2010-09-06
公開日2011-09-07
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Structural evidence for stabilization of inhibitor binding by a protein cavity in the dehaloperoxidase-hemoglobin from Amphitrite ornata.
Biopolymers, 98, 2012
6LXE
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BU of 6lxe by Molmil
DROSHA-DGCR8 complex
分子名称: Microprocessor complex subunit DGCR8, Ribonuclease 3, ZINC ION
著者Jin, W, Wang, J, Liu, C.P, Wang, H.W, Xu, R.M.
登録日2020-02-10
公開日2020-04-15
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structural Basis for pri-miRNA Recognition by Drosha.
Mol.Cell, 78, 2020
6MI3
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BU of 6mi3 by Molmil
Structure of NEMO(51-112) with N- and C-terminal coiled-coil adaptors.
分子名称: NF-kB ESSENTIAL MODULATOR,NF-kappa-B essential modulator,NF-kB ESSENTIAL MODULATOR
著者Pellegrini, M, Barczewski, A.H, Mierke, D.F, Ragusa, M.J.
登録日2018-09-19
公開日2019-07-31
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.783 Å)
主引用文献The IKK-binding domain of NEMO is an irregular coiled coil with a dynamic binding interface.
Sci Rep, 9, 2019
6MI4
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BU of 6mi4 by Molmil
Structure of the I65M mutant of NEMO(51-112) with N- and C-terminal coiled-coil adaptors.
分子名称: NF-kB ESSENTIAL MODULATOR
著者Pellegrini, M, Barczewski, A.H, Mierke, D.F, Ragusa, M.J.
登録日2018-09-19
公開日2019-08-07
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.50009418 Å)
主引用文献The IKK-binding domain of NEMO is an irregular coiled coil with a dynamic binding interface.
Sci Rep, 9, 2019
3UNM
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BU of 3unm by Molmil
Crystal Structure of The Human MDC1 FHA Domain
分子名称: Mediator of DNA damage checkpoint protein 1
著者Luo, S, Ye, K.
登録日2011-11-16
公開日2012-01-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural mechanism of the phosphorylation-dependent dimerization of the MDC1 forkhead-associated domain
Nucleic Acids Res., 40, 2012
3WGW
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BU of 3wgw by Molmil
Structure of PCNA bound to a small molecule inhibitor
分子名称: 4-{4-[(2S)-2-amino-3-hydroxypropyl]-2,6-diiodophenoxy}phenol, Proliferating cell nuclear antigen, SULFATE ION
著者Hashimoto, H.
登録日2013-08-12
公開日2014-02-05
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A small molecule inhibitor of monoubiquitinated Proliferating Cell Nuclear Antigen (PCNA) inhibits repair of interstrand DNA cross-link, enhances DNA double strand break, and sensitizes cancer cells to cisplatin.
J.Biol.Chem., 289, 2014
3VA4
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BU of 3va4 by Molmil
Crystal structure of the mammalian MDC1 FHA domain complexed with CHK2 pThr68 peptide
分子名称: Mediator of DNA damage checkpoint protein 1, Serine/threonine-protein kinase Chk2
著者Wu, H.H, Wu, P.Y, Huang, K.F, Kao, Y.Y, Tsai, M.D.
登録日2011-12-28
公開日2012-02-01
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献Structural Delineation of MDC1-FHA Domain Binding with CHK2-pThr68.
Biochemistry, 2012

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