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2FX9
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Crystal structure of hiv-1 neutralizing human fab 4e10 in complex with a thioether-linked peptide encompassing the 4e10 epitope on gp41
分子名称: Fab 4E10, Fragment of HIV glycoprotein gp41
著者Cardoso, R.M.F, Brunel, F.M, Ferguson, S, Burton, D.R, Dawson, P.E, Wilson, I.A.
登録日2006-02-03
公開日2006-12-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis of enhanced binding of extended and helically constrained peptide epitopes of the broadly neutralizing HIV-1 antibody 4E10.
J.Mol.Biol., 365, 2007
2FXA
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Structure of the Protease Production Regulatory Protein hpr from Bacillus subtilis.
分子名称: 1,2-ETHANEDIOL, HEXAETHYLENE GLYCOL, PENTAETHYLENE GLYCOL, ...
著者Cuff, M.E, Skarina, T, Edwards, A, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2006-02-03
公開日2006-03-14
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of the Protease Production Regulatory Protein hpr from Bacillus subtilis.
TO BE PUBLISHED
2FXD
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X-ray crystal structure of HIV-1 protease IRM mutant complexed with atazanavir (BMS-232632)
分子名称: (3S,8S,9S,12S)-3,12-BIS(1,1-DIMETHYLETHYL)-8-HYDROXY-4,11-DIOXO-9-(PHENYLMETHYL)-6-[[4-(2-PYRIDINYL)PHENYL]METHYL]-2,5, 6,10,13-PENTAAZATETRADECANEDIOIC ACID DIMETHYL ESTER, ACETATE ION, ...
著者Klei, H.E, Sheriff, S.
登録日2006-02-04
公開日2007-02-20
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献X-ray crystal structures of human immunodeficiency virus type 1 protease mutants complexed with atazanavir.
J.Virol., 81, 2007
2FXE
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X-ray crystal structure of HIV-1 protease CRM mutant complexed with atazanavir (BMS-232632)
分子名称: (3S,8S,9S,12S)-3,12-BIS(1,1-DIMETHYLETHYL)-8-HYDROXY-4,11-DIOXO-9-(PHENYLMETHYL)-6-[[4-(2-PYRIDINYL)PHENYL]METHYL]-2,5, 6,10,13-PENTAAZATETRADECANEDIOIC ACID DIMETHYL ESTER, ACETATE ION, ...
著者Sheriff, S, Klei, H.E.
登録日2006-02-05
公開日2007-02-20
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献X-ray crystal structures of human immunodeficiency virus type 1 protease mutants complexed with atazanavir.
J.Virol., 81, 2007
2FXF
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Human spermidine/spermine N1-acetyltransferase
分子名称: ACETATE ION, ACETYL COENZYME *A, CALCIUM ION, ...
著者Min, J.R, Wu, H, Zeng, H, Loppnau, P, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
登録日2006-02-05
公開日2006-02-14
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Crystal Structure of Human spermidine/spermine N1-acetyltransferase
To be Published
2FXI
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Arsenate reductase (ArsC from pI258) C10S/C15A double mutant with sulfate in its active site
分子名称: POTASSIUM ION, Protein arsC, SULFATE ION
著者Loris, R, Buts, L, Messens, J.
登録日2006-02-06
公開日2006-08-08
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Interplay Between Ion Binding and Catalysis in the Thioredoxin-coupled Arsenate Reductase Family.
J.Mol.Biol., 360, 2006
2FXK
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Crystal structure of the macro-domain of human core histone variant macroH2A1.1 (form A)
分子名称: H2A histone family, member Y isoform 1
著者Kustatscher, G, Hothorn, M, Pugieux, C, Scheffzek, K, Ladurner, A.G.
登録日2006-02-06
公開日2006-02-14
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献Splicing regulates NAD metabolite binding to histone macroH2A.
Nat.Struct.Mol.Biol., 12, 2005
2FXL
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Urate oxidase from aspergillus flavus complexed with allantoin
分子名称: 1-(2,5-DIOXO-2,5-DIHYDRO-1H-IMIDAZOL-4-YL)UREA, Uricase
著者Gabison, L, Chiadmi, M, Colloc'h, N, Prange, T.
登録日2006-02-06
公開日2006-05-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Recapture of [S]-allantoin, the product of the two-step degradation of uric acid, by urate oxidase.
Febs Lett., 580, 2006
2FXM
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Structure of the human beta-myosin S2 fragment
分子名称: MERCURY (II) ION, Myosin heavy chain, cardiac muscle beta isoform
著者Blankenfeldt, W, Thoma, N.H, Wray, J.S, Gautel, M, Schlichting, I.
登録日2006-02-06
公開日2006-11-21
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structures of human cardiac {beta}-myosin II S2-{Delta} provide insight into the functional role of the S2 subfragment
Proc.Natl.Acad.Sci.Usa, 103, 2006
2FXO
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Structure of the human beta-myosin S2 fragment
分子名称: Myosin heavy chain, cardiac muscle beta isoform
著者Blankenfeldt, W, Thoma, N.H, Wray, J.S, Gautel, M, Schlichting, I.
登録日2006-02-06
公開日2006-11-21
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structures of human cardiac {beta}-myosin II S2-{Delta} provide insight into the functional role of the S2 subfragment
Proc.Natl.Acad.Sci.Usa, 103, 2006
2FXP
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Solution Structure of the SARS-Coronavirus HR2 Domain
分子名称: Spike glycoprotein
著者Caffrey, M, Hakansson-McReynolds, S, Jiang, S.
登録日2006-02-06
公開日2006-03-07
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the severe acute respiratory syndrome-coronavirus heptad repeat 2 domain in the prefusion state
J.Biol.Chem., 281, 2006
2FXQ
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Single-stranded DNA-binding protein from Thermus aquaticus
分子名称: Single-strand binding protein
著者Dauter, Z, Jedrzejczak, R, Dauter, M.
登録日2006-02-06
公開日2006-02-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structure of the single-stranded DNA-binding protein SSB from Thermus aquaticus.
Acta Crystallogr.,Sect.D, 62, 2006
2FXR
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human beta tryptase II complexed with activated ketone inhibitor CRA-29382
分子名称: ALLYL {(1S)-1-[(5-{4-[(2,3-DIHYDRO-1H-INDEN-2-YLAMINO)CARBONYL]BENZYL}-1,2,4-OXADIAZOL-3-YL)CARBONYL]-3-PYRROLIDIN-3-YLPROPYL}CARBAMATE, Tryptase beta-2
著者Katz, B.A.
登録日2006-02-06
公開日2006-02-09
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure-guided design of Peptide-based tryptase inhibitors.
Biochemistry, 45, 2006
2FXS
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Yeast HSP82 in complex with the novel HSP90 Inhibitor Radamide
分子名称: ATP-dependent molecular chaperone HSP82, GLYCEROL, METHYL 3-CHLORO-2-{3-[(2,5-DIHYDROXY-4-METHOXYPHENYL)AMINO]-3-OXOPROPYL}-4,6-DIHYDROXYBENZOATE
著者Immormino, R.M, Gewirth, D.T.
登録日2006-02-06
公開日2007-02-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Different poses for ligand and chaperone in inhibitor-bound Hsp90 and GRP94: implications for paralog-specific drug design.
J.Mol.Biol., 388, 2009
2FXT
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Crystal Structure of Yeast Tim44
分子名称: Import inner membrane translocase subunit TIM44
著者Josyula, R, Sha, B.
登録日2006-02-06
公開日2007-02-06
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal Structure of Yeast Mitochondrial Peripheral Membrane Protein Tim44p C-terminal Domain.
J.Mol.Biol., 359, 2006
2FXU
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X-ray Structure of Bistramide A- Actin Complex at 1.35 A resolution.
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ...
著者Rizvi, S.A, Tereshko, V, Kossiakoff, A.A, Kozmin, S.A.
登録日2006-02-06
公開日2006-03-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Structure of bistramide a-actin complex at a 1.35 A resolution
J.Am.Chem.Soc., 128, 2006
2FXV
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Bacillus subtilis Xanthine Phosphoribosyltransferase in Complex with Guanosine 5'-monophosphate (GMP)
分子名称: GLYCEROL, GUANOSINE-5'-MONOPHOSPHATE, Xanthine phosphoribosyltransferase
著者Arent, S, Kadziola, A, Larsen, S, Neuhard, J, Jensen, K.F.
登録日2006-02-06
公開日2006-06-20
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献The Extraordinary Specificity of Xanthine Phosphoribosyltransferase from Bacillus subtilis Elucidated by Reaction Kinetics, Ligand Binding, and Crystallography
Biochemistry, 45, 2006
2FXY
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Solution structure of 55-72 segment of staphylococcal nuclease
分子名称: 18-mer peptide from Thermonuclease
著者Wang, M, Shan, L, Wang, J.F.
登録日2006-02-07
公開日2006-12-19
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Two peptide fragments G55-I72 and K97-A109 from staphylococcal nuclease exhibit different behaviors in conformational preferences for helix formation
Biopolymers, 83, 2006
2FXZ
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Solution structure of 97-109 segment of staphylococcal nuclease
分子名称: 13-mer peptide from Thermonuclease
著者Wang, M, Shan, L, Wang, J.F.
登録日2006-02-07
公開日2006-12-19
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Two peptide fragments G55-I72 and K97-A109 from staphylococcal nuclease exhibit different behaviors in conformational preferences for helix formation
Biopolymers, 83, 2006
2FY1
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A dual mode of RNA recognition by the RBMY protein
分子名称: RNA-binding motif protein, Y chromosome, family 1 member A1, ...
著者Skrisovska, L, Bourgois, C, Stefl, R, Kister, L, Wenter, P, Elliot, D, Stevenin, J, Allain, F.H.T.
登録日2006-02-07
公開日2007-02-06
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献The testis-specific human protein RBMY recognizes RNA through a novel mode of interaction.
EMBO Rep., 8, 2007
2FY2
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Structures of ligand bound human choline acetyltransferase provide insight into regulation of acetylcholine synthesis
分子名称: Choline O-acetyltransferase
著者Kim, A.R, Rylett, R.J, Shilton, B.H.
登録日2006-02-07
公開日2006-12-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Substrate binding and catalytic mechanism of human choline acetyltransferase.
Biochemistry, 45, 2006
2FY3
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Structures of ligand bound human choline acetyltransferase provides insight into regulation of acetylcholine synthesis
分子名称: CHOLINE ION, Choline O-acetyltransferase, GLYCEROL
著者Kim, A.R, Rylett, R.J, Shilton, B.H.
登録日2006-02-07
公開日2006-12-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Substrate binding and catalytic mechanism of human choline acetyltransferase.
Biochemistry, 45, 2006
2FY4
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Structures of ligand bound human choline acetyltransferase provide insight into regulation of acetylcholine synthesis
分子名称: COENZYME A, Choline O-acetyltransferase
著者Kim, A.R, Rylett, R.J, Shilton, B.H.
登録日2006-02-07
公開日2006-12-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Substrate binding and catalytic mechanism of human choline acetyltransferase.
Biochemistry, 45, 2006
2FY5
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Structures of ligand bound human choline acetyltransferase provide insight into regulation of acetylcholine synthesis
分子名称: Choline O-acetyltransferase, [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-4-HYDROXY-3-(PHOSPHONOOXY)TETRAHYDROFURAN-2-YL]METHYL (3R)-3-HYDROXY-2,2-DIMETHYL-4-OXO-4-{[3-OXO-3-({2-[(2-OXOPROPYL)THIO]ETHYL}AMINO)PROPYL]AMINO}BUTYL DIHYDROGEN DIPHOSPHATE
著者Kim, A.R, Rylett, R.J, Shilton, B.H.
登録日2006-02-07
公開日2006-12-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Substrate binding and catalytic mechanism of human choline acetyltransferase.
Biochemistry, 45, 2006
2FY6
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Structure of the N-terminal domain of Neisseria meningitidis PilB
分子名称: CHLORIDE ION, Peptide methionine sulfoxide reductase msrA/msrB, SULFATE ION
著者Ranaivoson, F.M, Kauffmann, B, Neiers, F, Boschi-Muller, S, Branlant, G, Favier, F.
登録日2006-02-07
公開日2006-04-04
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The X-ray Structure of the N-terminal Domain of PILB from Neisseria meningitidis Reveals a Thioredoxin-fold
J.Mol.Biol., 358, 2006

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