2FY4

Structures of ligand bound human choline acetyltransferase provide insight into regulation of acetylcholine synthesis

Summary for 2FY4

Entry DOI	10.2210/pdb2fy4/pdb
Related	2fy2 2fy3 2fy5
Descriptor	Choline O-acetyltransferase, COENZYME A (3 entities in total)
Functional Keywords	two domain, alpha-beta protein, transferase, coenzyme a
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	68880.89
Authors	Kim, A.R.,Rylett, R.J.,Shilton, B.H. (deposition date: 2006-02-07, release date: 2006-12-12, Last modification date: 2023-08-30)
Primary citation	Kim, A.R.,Rylett, R.J.,Shilton, B.H. Substrate binding and catalytic mechanism of human choline acetyltransferase. Biochemistry, 45:14621-14631, 2006 Cited by PubMed: 17144655 DOI: 10.1021/bi061536l PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation