2FXO
Structure of the human beta-myosin S2 fragment
Summary for 2FXO
| Entry DOI | 10.2210/pdb2fxo/pdb |
| Related | 1nkn 2fxm |
| Descriptor | Myosin heavy chain, cardiac muscle beta isoform (1 entity in total) |
| Functional Keywords | coiled coil (dimeric, parallel), familial hypertrophic cardiomyopathy, fhc-associated mutant e924k, thick filament, contractile protein |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm, myofibril : P12883 |
| Total number of polymer chains | 4 |
| Total formula weight | 60424.58 |
| Authors | Blankenfeldt, W.,Thoma, N.H.,Wray, J.S.,Gautel, M.,Schlichting, I. (deposition date: 2006-02-06, release date: 2006-11-21, Last modification date: 2023-10-25) |
| Primary citation | Blankenfeldt, W.,Thoma, N.H.,Wray, J.S.,Gautel, M.,Schlichting, I. Crystal structures of human cardiac {beta}-myosin II S2-{Delta} provide insight into the functional role of the S2 subfragment Proc.Natl.Acad.Sci.Usa, 103:17713-17717, 2006 Cited by PubMed: 17095604DOI: 10.1073/pnas.0606741103 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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