PDB: 42250 件ウェブページステータス検索Chemie searchBIRD

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8CU7	Crystal structure of A2AAR-StaR2-bRIL in complex with a novel A2a antagonist, LJ-4517 分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2R,3R,4R)-2-[(8P)-6-amino-2-(hex-1-yn-1-yl)-8-(thiophen-2-yl)-9H-purin-9-yl]oxolane-3,4-diol, Adenosine receptor A2a,Soluble cytochrome b562, ... 著者 Shiriaeva, A, Park, D.-J, Kim, G, Lee, Y, Hou, X, Jarhad, D.B, Kim, G, Yu, J, Hyun, Y.E, Kim, W, Gao, Z.-G, Jacobson, K.A, Han, G.W, Stevens, R.C, Jeong, L.S, Choi, S, Cherezov, V. 登録日 2022-05-16 公開日 2022-08-31 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 GPCR Agonist-to-Antagonist Conversion: Enabling the Design of Nucleoside Functional Switches for the A 2A Adenosine Receptor. J.Med.Chem., 65, 2022
6DFK	Crystal structure of the 11S subunit of the Plasmodium falciparum proteasome, PA28 分子名称: SULFATE ION, Subunit of proteaseome activator complex,putative 著者 Xie, S.C, Metcalfe, R.D, Gillett, D.L, Tilley, L, Griffin, M.D.W. 登録日 2018-05-15 公開日 2019-08-07 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 The structure of the PA28-20S proteasome complex from Plasmodium falciparum and implications for proteostasis. Nat Microbiol, 4, 2019
6T1B	Crystal structure of YlmD from Geobacillus stearothermophilus in complex with inosine 分子名称: INOSINE, YlmD, ZINC ION 著者 Reikine, S, Modis, Y. 登録日 2019-10-03 公開日 2020-01-29 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 FAMIN Is a Multifunctional Purine Enzyme Enabling the Purine Nucleotide Cycle. Cell, 180, 2020
3IM1	Structure of the C-terminal Sec63 unit of yeast Brr2, P212121 Form 分子名称: Pre-mRNA-splicing helicase BRR2 著者 Pena, V, Hrmann, R.L, Wahl, M.C. 登録日 2009-08-09 公開日 2009-08-25 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Common Design Principles in the Spliceosomal RNA Helicase Brr2 and in the Hel308 DNA Helicase To be Published
6T0Y	Crystal structure of YlmD from Geobacillus stearothermophilus 分子名称: Polyphenol oxidase, ZINC ION 著者 Reikine, S, Modis, Y. 登録日 2019-10-03 公開日 2020-01-29 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 FAMIN Is a Multifunctional Purine Enzyme Enabling the Purine Nucleotide Cycle. Cell, 180, 2020
3MDC	DNA polymerase lambda in complex with dFdCTP 分子名称: 2'-deoxy-2',2'-difluorocytidine 5'-(tetrahydrogen triphosphate), DNA (5'-D(*CP*AP*GP*TP*AP*C)-3'), DNA (5'-D(*CP*GP*GP*CP*GP*GP*TP*AP*CP*TP*G)-3'), ... 著者 Garcia-Diaz, M, Murray, M, Kunkel, T, Chou, K.M. 登録日 2010-03-30 公開日 2010-04-28 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.999 Å) 主引用文献 Interaction between DNA Polymerase lambda and anticancer nucleoside analogs. J.Biol.Chem., 285, 2010
418D	5'-R(*GP*UP*GP*CP*AP*CP*A)-D(P*C)-3' 分子名称: RNA (5'-R(*GP*UP*GP*CP*AP*CP*AP*C)-3') 著者 Mitra, S.N, Biswas, R, Shi, K, Sundaralingam, M. 登録日 1998-08-12 公開日 2003-06-10 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of an RNA duplex [r(gugcaca)dC]2 with 3'-dinucleoside overhangs forming a superhelix. J.Biomol.Struct.Dyn., 11, 2000
5AO0	Crystal structure of human SAMHD1 (amino acid residues 41-583) bound to ddGTP 分子名称: 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1, FE (III) ION, ... 著者 Schwefel, D, Taylor, I.A. 登録日 2015-09-09 公開日 2015-10-14 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (3.731 Å) 主引用文献 Phospho-Dependent Regulation of Samhd1 Oligomerisation Couples Catalysis and Restriction. Plos Pathog., 11, 2015
5CSO	Structure of the complex of type 1 ribosome inactivating protein from Momordica balsamina with a nucleoside, cytidine at 1.78 A resolution 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-AMINO-1-BETA-D-RIBOFURANOSYL-2(1H)-PYRIMIDINONE, GLYCEROL, ... 著者 Yamin, S, Pandey, S, Kaur, P, Sharma, S, Singh, T.P. 登録日 2015-07-23 公開日 2015-08-12 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Binding and structural studies of the complexes of type 1 ribosome inactivating protein fromMomordica balsaminawith cytosine, cytidine, and cytidine diphosphate. Biochem Biophys Rep, 4, 2015
1TUM	MUTT PYROPHOSPHOHYDROLASE-METAL-NUCLEOTIDE-METAL COMPLEX, NMR, 16 STRUCTURES 分子名称: COBALT TETRAAMMINE ION, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, MAGNESIUM ION, ... 著者 Lin, J, Abeygunawardana, C, Frick, D.N, Bessman, M.J, Mildvan, A.S. 登録日 1996-12-05 公開日 1997-05-15 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Solution structure of the quaternary MutT-M2+-AMPCPP-M2+ complex and mechanism of its pyrophosphohydrolase action. Biochemistry, 36, 1997
4DAA	CRYSTALLOGRAPHIC STRUCTURE OF D-AMINO ACID AMINOTRANSFERASE IN PYRIDOXAL-5'-PHOSPHATE (PLP) FORM 分子名称: D-AMINO ACID AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE, SULFATE ION 著者 Peisach, D, Chipman, D.M, Ringe, D. 登録日 1998-01-26 公開日 1998-04-29 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystallographic study of steps along the reaction pathway of D-amino acid aminotransferase. Biochemistry, 37, 1998
9EIL	SIRT6 bound to an H3K27Ac nucleosome 分子名称: DNA (185-MER), Histone H2A type 1, Histone H2B, ... 著者 Markert, J, Wang, Z, Cole, P, Farnung, L. 登録日 2024-11-26 公開日 2025-07-09 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structural and enzymatic plasticity of SIRT6 deacylase activity. J.Biol.Chem., 301, 2025
5BJT	Crystal structure of human FcRn with a peptide inhibitor at multiple sites 分子名称: Beta-2-microglobulin, IgG receptor FcRn large subunit p51, peptide inhibitor 著者 Nienaber, V, Badger, J. 登録日 2016-10-23 公開日 2017-03-22 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Hepatic FcRn regulates albumin homeostasis and susceptibility to liver injury. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
1SPG	CARBONMONOXY HEMOGLOBIN FROM THE TELEOST FISH LEIOSTOMUS XANTHURUS 分子名称: CARBON MONOXIDE, HEMOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE 著者 Mylvaganam, S.E, Getzoff, E.D. 登録日 1996-02-05 公開日 1997-03-12 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural basis for the root effect in haemoglobin. Nat.Struct.Biol., 3, 1996
4L6C	Crystal structure of human mitochondrial deoxyribonucleotidase in complex with the inhibitor pib-t 分子名称: 1,2-ETHANEDIOL, 1-{2-deoxy-3,5-O-[(4-iodophenyl)(phosphono)methylidene]-beta-D-threo-pentofuranosyl}-5-methylpyrimidine-2,4(1H,3H)-dione, 5'(3')-deoxyribonucleotidase, ... 著者 Pachl, P, Brynda, J, Rezacova, P. 登録日 2013-06-12 公開日 2014-09-10 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Conformationally constrained nucleoside phosphonic acids - potent inhibitors of human mitochondrial and cytosolic 5'(3')-nucleotidases. Org.Biomol.Chem., 12, 2014
2B6A	Crystal structure of HIV-1 reverse transcriptase (RT) in complex with THR-50 分子名称: 1-(2,6-DIFLUOROBENZYL)-2-(2,6-DIFLUOROPHENYL)-4-METHYL-1H-BENZIMIDAZOLE, Reverse transcriptase p51 subunit, Reverse transcriptase p66 subunit 著者 Morningstar, M.L, Roth, T, Smith, M.K, Zajac, M, Watson, K, Buckheit, R.W, Das, K, Zhang, W, Arnold, E, Michejda, C.J. 登録日 2005-09-30 公開日 2005-11-01 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Crystal structure of HIV-1 reverse transcriptase (RT) in complex with THR-50 TO BE PUBLISHED
6X59	The mouse cGAS catalytic domain binding to human assembled nucleosome 分子名称: Cyclic GMP-AMP synthase, DNA, Histone H2A type 1, ... 著者 Pengbiao, X, Pingwei, L, Baoyu, Z. 登録日 2020-05-25 公開日 2020-09-16 最終更新日 2025-05-28 実験手法 ELECTRON MICROSCOPY (2.98 Å) 主引用文献 The molecular basis of tight nuclear tethering and inactivation of cGAS. Nature, 587, 2020
8PP7	human RYBP-PRC1 bound to mononucleosome 分子名称: DNA (215-mer), E3 ubiquitin-protein ligase RING2, Histone H2A, ... 著者 Ciapponi, M, Benda, C, Mueller, J. 登録日 2023-07-06 公開日 2024-03-27 最終更新日 2025-07-09 実験手法 ELECTRON MICROSCOPY (2.91 Å) 主引用文献 Structural basis of the histone ubiquitination read-write mechanism of RYBP-PRC1. Nat.Struct.Mol.Biol., 31, 2024
481D	CRYSTAL STRUCTURE OF A HEXITOL NUCLEIC ACID (HNA) DUPLEX AT 1.6A RESOLUTION 分子名称: 5'-H(*(6HG)P*(6HT)P*(6HG)P*(6HT)P*(6HA)P*(6HC)P*(6HA)P*(6HC))-3' 著者 Declercq, R, Van Meervelt, L. 登録日 1999-07-23 公開日 2002-04-27 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structure of double helical hexitol nucleic acids. J.Am.Chem.Soc., 124, 2002
6XJD	Two mouse cGAS catalytic domain binding to human assembled nucleosome 分子名称: Cyclic GMP-AMP synthase, DNA (145-MER), Histone H2A type 1, ... 著者 Xu, P, Li, P, Zhao, B. 登録日 2020-06-23 公開日 2020-09-16 最終更新日 2025-05-28 実験手法 ELECTRON MICROSCOPY (6.8 Å) 主引用文献 The molecular basis of tight nuclear tethering and inactivation of cGAS. Nature, 587, 2020
6X5A	The mouse cGAS catalytic domain binding to human nucleosome that purified from HEK293T cells 分子名称: Cyclic GMP-AMP synthase, DNA (natural), Histone H2A type 1, ... 著者 Pengbiao, X, Pingwei, L, Baoyu, Z. 登録日 2020-05-25 公開日 2020-09-16 最終更新日 2025-05-28 実験手法 ELECTRON MICROSCOPY (4.36 Å) 主引用文献 The molecular basis of tight nuclear tethering and inactivation of cGAS. Nature, 587, 2020
7R1F	Early transcription elongation state of influenza B polymerase backtracked due to double incoproation of nucleotide analogue T1106 分子名称: 3' vRNA, 5' vRNA, MAGNESIUM ION, ... 著者 Cusack, S, Kouba, T. 登録日 2022-02-02 公開日 2022-12-28 最終更新日 2025-07-09 実験手法 ELECTRON MICROSCOPY (2.58 Å) 主引用文献 Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106. Cell Rep, 42, 2023
7R0E	Early transcription elongation state of influenza A/H7N9 polymerase backtracked due to double incoproation of nucleotide analogue T1106 and with singly incoporated T1106 at the +1 position 分子名称: 3' vRNA, 5' vRNA, MAGNESIUM ION, ... 著者 Cusack, S, Kouba, T. 登録日 2022-02-01 公開日 2022-12-28 最終更新日 2025-07-09 実験手法 ELECTRON MICROSCOPY (2.51 Å) 主引用文献 Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106. Cell Rep, 42, 2023
5AO1	Crystal structure of human SAMHD1 (amino acid residues 115-583) bound to ddGTP 分子名称: 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1, FE (III) ION, ... 著者 Schwefel, D, Taylor, I.A. 登録日 2015-09-09 公開日 2015-10-14 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.545 Å) 主引用文献 Phospho-Dependent Regulation of Samhd1 Oligomerisation Couples Catalysis and Restriction. Plos Pathog., 11, 2015
5AO2	Crystal structure of human SAMHD1 (amino acid residues 115-583) R164A variant bound to dGTP 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1, FE (III) ION 著者 Schwefel, D, Taylor, I.A. 登録日 2015-09-09 公開日 2015-10-14 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.966 Å) 主引用文献 Phospho-Dependent Regulation of Samhd1 Oligomerisation Couples Catalysis and Restriction. Plos Pathog., 11, 2015

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