6YF8
 
 | | DYRK1A with PST001 | | 分子名称: | Dual specificity tyrosine-phosphorylation-regulated kinase 1A, ~{N}-[5-(5-methoxy-1,3-benzothiazol-2-yl)pyridin-3-yl]ethanamide | | 著者 | Rothweiler, U. | | 登録日 | 2020-03-26 | | 公開日 | 2021-04-07 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (3.198 Å) | | 主引用文献 | DYRK1A with PST001
To Be Published
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8T0S
 | | Crystal structure of UBE2G2 adduct with phenethyl isothiocyanate (PEITC) at the Cys48 position | | 分子名称: | 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase AMFR, Ubiquitin-conjugating enzyme E2 G2 | | 著者 | Wang, C, Shaw, G.X, Shi, G, Ji, X. | | 登録日 | 2023-06-01 | | 公開日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Crystal structure of UBE2G2 adduct with phenethyl isothiocyanate (PEITC) at the Cys48 position
To be published
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6YGU
 | | Crystal structure of the minimal Mtr4-Red1 complex (single chain) from Chaetomium thermophilum | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, ATP dependent RNA helicase (Dob1)-like protein, ... | | 著者 | Dobrev, N, Ahmed, Y.L, Sinning, I. | | 登録日 | 2020-03-27 | | 公開日 | 2021-05-05 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | The zinc-finger protein Red1 orchestrates MTREC submodules and binds the Mtl1 helicase arch domain.
Nat Commun, 12, 2021
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8TCK
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8Z56
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6OCD
 | | Ricin A chain bound to VHH antibody V6D4 | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, IMIDAZOLE, ... | | 著者 | Rudolph, M.J. | | 登録日 | 2019-03-22 | | 公開日 | 2020-04-01 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (2.103 Å) | | 主引用文献 | Intracellular Neutralization of Ricin Toxin by Single-domain Antibodies Targeting the Active Site.
J.Mol.Biol., 432, 2020
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5NSA
 | | Beta domain of human transcobalamin bound to Co-beta-[2-(2,4-difluorophenyl)ethinyl]cobalamin | | 分子名称: | 1-ethynyl-2,4-difluorobenzene, CALCIUM ION, COBALAMIN, ... | | 著者 | Bloch, J.S, Ruetz, M, Krautler, B, Locher, K.P. | | 登録日 | 2017-04-25 | | 公開日 | 2017-09-27 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.273 Å) | | 主引用文献 | Structure of the human transcobalamin beta domain in four distinct states.
PLoS ONE, 12, 2017
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8RHO
 | | [2Fe:2S] ferredoxin FeSII from Azotobacter vinelandii, reduced form | | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, FE2/S2 (INORGANIC) CLUSTER, ... | | 著者 | Franke, P, Zhang, L, Einsle, O. | | 登録日 | 2023-12-15 | | 公開日 | 2025-01-01 | | 最終更新日 | 2025-02-05 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Conformational protection of molybdenum nitrogenase by Shethna protein II.
Nature, 637, 2025
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8DKO
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6QNC
 | | Liquid Application Method for time-resolved Analyses (LAMA) by serial synchrotron crystallography, Xylose Isomerase 0.1 s timepoint | | 分子名称: | COBALT (II) ION, MAGNESIUM ION, Xylose isomerase, ... | | 著者 | Mehrabi, P, Schulz, E.C, Miller, R.J.D. | | 登録日 | 2019-02-10 | | 公開日 | 2019-10-02 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (1.897 Å) | | 主引用文献 | Liquid application method for time-resolved analyses by serial synchrotron crystallography.
Nat.Methods, 16, 2019
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6VRF
 | | ADP bound TTBK2 kinase domain | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | | 著者 | Chodaparambil, J.V, Marcotte, D.J. | | 登録日 | 2020-02-07 | | 公開日 | 2020-06-03 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Mechanisms of Regulation and Diverse Activities of Tau-Tubulin Kinase (TTBK) Isoforms.
Cell Mol Neurobiol, 41, 2021
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8DLB
 | | Room temperature X-ray structure of SARS-CoV-2 main protease in complex with compound Z2799209083 | | 分子名称: | 1-[(5S)-5-(3,4-dimethoxyphenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl]ethan-1-one, 3C-like proteinase | | 著者 | Kovalevsky, A.Y, Coates, L, Kneller, D.W. | | 登録日 | 2022-07-07 | | 公開日 | 2023-05-17 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | AI-Accelerated Design of Targeted Covalent Inhibitors for SARS-CoV-2.
J.Chem.Inf.Model., 63, 2023
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8TZD
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8DMD
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7RTI
 | | X-ray structure of RBPJ-L3MBTL3(dT62)-DNA complex | | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(*AP*AP*TP*CP*TP*TP*TP*CP*CP*CP*AP*CP*GP*GP*T)-3'), DNA (5'-D(*TP*TP*AP*CP*CP*GP*TP*GP*GP*GP*AP*AP*AP*GP*A)-3'), ... | | 著者 | Hall, D.P, Kovall, R.A, Yuan, Z. | | 登録日 | 2021-08-13 | | 公開日 | 2022-08-24 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | The structure, binding and function of a Notch transcription complex involving RBPJ and the epigenetic reader protein L3MBTL3.
Nucleic Acids Res., 50, 2022
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8TZ7
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8G4J
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8TZ8
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7BWQ
 | | Structure of nonstructural protein Nsp9 from SARS-CoV-2 | | 分子名称: | Nsp9, SULFATE ION | | 著者 | Zhang, C, Chen, Y, Li, L, Su, D. | | 登録日 | 2020-04-15 | | 公開日 | 2021-07-21 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.954 Å) | | 主引用文献 | Structural basis for the multimerization of nonstructural protein nsp9 from SARS-CoV-2.
Mol Biomed, 1, 2020
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6OIP
 | | Crystal structure of MYST acetyltransferase domain in complex with inhibitor 34 | | 分子名称: | 2-fluoro-3-methyl-N'-[(naphthalen-2-yl)sulfonyl]benzohydrazide, GLYCEROL, Histone acetyltransferase KAT8, ... | | 著者 | Hermans, S.J, Chung, M.C, Parker, M.W, Thomas, T, Baell, J.B. | | 登録日 | 2019-04-09 | | 公開日 | 2019-07-03 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Discovery of Benzoylsulfonohydrazides as Potent Inhibitors of the Histone Acetyltransferase KAT6A.
J.Med.Chem., 62, 2019
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4XME
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8ECG
 | | Complex of HMG1 with pitavastatin | | 分子名称: | 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1, GLYCEROL, Pitavastatin | | 著者 | Haywood, J, Bond, C.S. | | 登録日 | 2022-09-01 | | 公開日 | 2022-09-14 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | | 主引用文献 | A fungal tolerance trait and selective inhibitors proffer HMG-CoA reductase as a herbicide mode-of-action.
Nat Commun, 13, 2022
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8UB5
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7S1N
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4XMH
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